Personal information

Countries

Germany, Netherlands, United States

Activities

Collapse all

Employment (2)

Weill Cornell Medicine: New York, NY, US

2021 to present | Post-doctoral Associate (BMRI)
Employment
Source: Self-asserted source
Till S. Zimmer

Academic Medical Center: Amsterdam, Noord-Holland, NL

2017-01-01 to 2021-05 | PhD (Neuropathology)
Employment
Source: Self-asserted source
Till S. Zimmer

Education and qualifications (2)

Rheinische Friedrich-Wilhelms-Universität Bonn: Bonn, DE

2014 to 2016 | Master of Science (Medicine)
Education
Source: Self-asserted source
Till S. Zimmer

Hochschule Bonn-Rhein-Sieg - Campus Rheinbach: Rheinbach, Nordrhein-Westfalen, DE

2010 to 2013
Qualification
Source: Self-asserted source
Till S. Zimmer

Professional activities (5)

New York Academy of Sciences: New York, US

Membership
Source: Self-asserted source
Till S. Zimmer

National Postdoctoral Association: Washington, US

Membership
Source: Self-asserted source
Till S. Zimmer

Marie Curie Alumni Association: Brussels, BE

Membership
Source: Self-asserted source
Till S. Zimmer

Appel Postdoc Initiative: New York, NY, US

2022 to 2024 | Organizing committee (Helen & Robert Appel Alzheimer's Disease Research Institute)
Service
Source: Self-asserted source
Till S. Zimmer

ONWAR: Amsterdam, NL

2017 to 2021
Membership
Source: Self-asserted source
Till S. Zimmer

Funding (2)

Molecular mechanisms and effects of Alzheimer’s-related lipid dysregulation in astrocytes

2023-07-01 to 2025-07-01 | Grant
BrightFocus Foundation (Clarksburg, US)
GRANT_NUMBER:

A2023008F
Source: check_circle
BrightFocus Foundation - ProposalCentral

Molecular mechanisms and effects of Alzheimer’s-related lipid dysregulation

2023-03 to 2026-02 | Award
Alzheimer's Association (Chicago, US)
URL: https://www.alz.org/research/for_researchers/grants/types-of-grants/alzheimer_s_association_research_fellowship_(aarf)
GRANT_NUMBER:

23AARF-1029892
Source: Self-asserted source
Till S. Zimmer

Works (24)

Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology

2024-08-20 | Preprint
DOI: 10.1101/2024.08.19.608708
Contributors: Daniel Barnett; Till S. Zimmer; Caroline Booraem; Fernando Palaguachi; Samantha M. Meadows; Haopeng Xiao; Edward T. Chouchani; Anna G. Orr; Adam L. Orr
Source: check_circle
Crossref

Hippocampal astrocytes induce sex-dimorphic effects on memory

Cell Reports
2024-06 | Journal article
DOI: 10.1016/j.celrep.2024.114278
Part of ISSN: 2211-1247
Contributors: Samantha M. Meadows; Fernando Palaguachi; Minwoo Wendy Jang; Avital Licht-Murava; Daniel Barnett; Till S. Zimmer; Constance Zhou; Samantha R. McDonough; Adam L. Orr; Anna Orr
Source: Self-asserted source
Till S. Zimmer

Astrocytes in selective vulnerability to neurodegenerative disease

Trends in Neurosciences
2024-04 | Journal article
DOI: 10.1016/j.tins.2024.02.008
Part of ISSN: 0166-2236
Contributors: Till S. Zimmer; Adam L. Orr; Anna Orr
Source: Self-asserted source
Till S. Zimmer

Loss of maturity and homeostatic functions in Tuberous Sclerosis Complex-derived astrocytes

Frontiers in Cellular Neuroscience
2023-11-28 | Journal article
DOI: 10.3389/fncel.2023.1284394
Part of ISSN: 1662-5102
Contributors: Mark J. Luinenburg; Mirte Scheper; Frederik N. F. Sørensen; Jasper J. Anink; Wim Van Hecke; Irina Korshunova; Floor E. Jansen; Kate Riney; Pieter van Eijsden; Peter Gosselaar et al.
Source: Self-asserted source
Till S. Zimmer

Down-regulation of the brain-specific cell-adhesion molecule contactin-3 in tuberous sclerosis complex during the early postnatal period

Journal of Neurodevelopmental Disorders
2022-12 | Journal article
DOI: 10.1186/s11689-022-09416-2
Part of ISSN: 1866-1947
Part of ISSN: 1866-1955
Contributors: Anatoly Korotkov; Mark J. Luinenburg; Alessia Romagnolo; Till S. Zimmer; Jackelien van Scheppingen; Anika Bongaarts; Diede W. M. Broekaart; Jasper J. Anink; Caroline Mijnsbergen; Floor E. Jansen et al.
Source: Self-asserted source
Till S. Zimmer

Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia

Molecular Neurodegeneration
2022-12 | Journal article
DOI: 10.1186/s13024-022-00547-7
Part of ISSN: 1750-1326
Contributors: Dan Xia; Steve Lianoglou; Thomas Sandmann; Meredith Calvert; Jung H. Suh; Elliot Thomsen; Jason Dugas; Michelle E. Pizzo; Sarah L. DeVos; Timothy K. Earr et al.
Source: Self-asserted source
Till S. Zimmer

Cholesterol 24-hydroxylase is a novel pharmacological target for anti-ictogenic and disease modification effects in epilepsy

Neurobiology of Disease
2022-10 | Journal article
DOI: 10.1016/j.nbd.2022.105835
Part of ISSN: 0969-9961
Contributors: Alessia Salamone; Gaetano Terrone; Rossella Di Sapia; Silvia Balosso; Teresa Ravizza; Luca Beltrame; Ilaria Craparotta; Laura Mannarino; Sara Raimondi Cominesi; Massimo Rizzi et al.
Source: Self-asserted source
Till S. Zimmer

The Gelatinase Inhibitor ACT-03 Reduces Gliosis in the Rapid Kindling Rat Model of Epilepsy, and Attenuates Inflammation and Loss of Barrier Integrity In Vitro

Biomedicines
2022-08-29 | Journal article
DOI: 10.3390/biomedicines10092117
Part of ISSN: 2227-9059
Contributors: Diede W. M. Broekaart; Till S. Zimmer; Sophie Cohen; Rianne Tessers; Jasper J. Anink; Helga E. de Vries; Jan A. Gorter; Roger Prades; Eleonora Aronica; Erwin van Vliet
Source: Self-asserted source
Till S. Zimmer

Increased expression of complement components in tuberous sclerosis complex and focal cortical dysplasia type 2B brain lesions

Epilepsia
2022-02 | Journal article
DOI: 10.1111/epi.17139
Part of ISSN: 0013-9580
Part of ISSN: 1528-1167
Contributors: Victoria‐Elisabeth Gruber; Mark J. Luinenburg; Katrin Colleselli; Verena Endmayr; Jasper J. Anink; Till S. Zimmer; Floor Jansen; Peter Gosselaar; Roland Coras; Theresa Scholl et al.
Source: Self-asserted source
Till S. Zimmer

Balloon cells promote immune system activation in focal cortical dysplasia type 2b

Neuropathology and Applied Neurobiology
2021-10 | Journal article
DOI: 10.1111/nan.12736
Contributors: Till S. Zimmer; Diede W. M. Broekaart; Mark Luinenburg; Caroline Mijnsbergen; Jasper J. Anink; Nam Suk Sim; Iliana Michailidou; Floor E. Jansen; Peter C. van Rijen; Jeong Ho Lee et al.
Source: check_circle
Crossref

CXCL1-CXCR1/2 signaling is induced in human temporal lobe epilepsy and contributes to seizures in a murine model of acquired epilepsy

Neurobiology of Disease
2021-10 | Journal article
DOI: 10.1016/j.nbd.2021.105468
Part of ISSN: 0969-9961
Source: Self-asserted source
Till S. Zimmer

MicroRNA‐34a activation in tuberous sclerosis complex during early brain development may lead to impaired corticogenesis

Neuropathology and Applied Neurobiology
2021-10 | Journal article
DOI: 10.1111/nan.12717
Contributors: Anatoly Korotkov; Nam Suk Sim; Mark J. Luinenburg; Jasper J. Anink; Jackelien van Scheppingen; Till S. Zimmer; Anika Bongaarts; Diede W. M. Broekaart; Caroline Mijnsbergen; Floor E. Jansen et al.
Source: check_circle
Crossref

Upregulation of the pathogenic transcription factor SPI1/PU.1 in tuberous sclerosis complex and focal cortical dysplasia by oxidative stress

Brain Pathology
2021-09 | Journal article
DOI: 10.1111/bpa.12949
Contributors: Till S. Zimmer; Anatoly Korotkov; Susan Zwakenberg; Floor E. Jansen; Fried J. T. Zwartkruis; Nicholas R. Rensing; Michael Wong; Angelika Mühlebner; Erwin A. van Vliet; Eleonora Aronica et al.
Source: check_circle
Crossref

Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy

Acta Neuropathologica
2021-07-22 | Journal article
DOI: 10.1007/s00401-021-02348-6
Part of ISSN: 0001-6322
Part of ISSN: 1432-0533
Source: Self-asserted source
Till S. Zimmer

Seizure activity and brain damage in a model of focal non‐convulsive status epilepticus

Neuropathology and Applied Neurobiology
2021-01-27 | Journal article
DOI: 10.1111/nan.12693
Part of ISSN: 0305-1846
Part of ISSN: 1365-2990
Source: Self-asserted source
Till S. Zimmer
grade
Preferred source (of 2)‎

Chronic activation of anti‐oxidant pathways and iron accumulation in epileptogenic malformations

Neuropathology and Applied Neurobiology
2020-10 | Journal article
DOI: 10.1111/nan.12596
Contributors: T. S. Zimmer; G. Ciriminna; A. Arena; J. J. Anink; A. Korotkov; F. E. Jansen; W. van Hecke; W. G. Spliet; P. C. van Rijen; J. C. Baayen et al.
Source: check_circle
Crossref

Myelin Pathology Beyond White Matter in Tuberous Sclerosis Complex (TSC) Cortical Tubers

Journal of Neuropathology & Experimental Neurology
2020-10-01 | Journal article
DOI: 10.1093/jnen/nlaa090
Part of ISSN: 0022-3069
Part of ISSN: 1554-6578
Source: Self-asserted source
Till S. Zimmer

Tuberous Sclerosis Complex as Disease Model for Investigating mTOR-Related Gliopathy During Epileptogenesis

Frontiers in Neurology
2020-09-17 | Journal article
DOI: 10.3389/fneur.2020.01028
Part of ISSN: 1664-2295
Source: Self-asserted source
Till S. Zimmer

Oxidative stress and inflammation in a spectrum of epileptogenic cortical malformations: molecular insights into their interdependence

Brain Pathology
2018-10-10 | Journal article
DOI: 10.1111/bpa.12661
Contributors: Andrea Arena; Till S. Zimmer; Jackelien van Scheppingen; Anatoly Korotkov; Jasper J. Anink; Angelika Mühlebner; Floor E. Jansen; Wim van Hecke; Wim G. Spliet; Peter C. van Rijen et al.
Source: check_circle
Crossref

Cannabinoid 1 Receptor Signaling on Hippocampal GABAergic Neurons Influences Microglial Activity

Frontiers in Molecular Neuroscience
2018-08-28 | Journal article
DOI: 10.3389/fnmol.2018.00295
Part of ISSN: 1662-5099
Source: Self-asserted source
Till S. Zimmer

Cannabinoid 1 receptor signaling on GABAergic neurons influences astrocytes in the ageing brain

PLOS ONE
2018-08-16 | Journal article
DOI: 10.1371/journal.pone.0202566
Part of ISSN: 1932-6203
Source: Self-asserted source
Till S. Zimmer

miR147b: A novel key regulator of interleukin 1 beta-mediated inflammation in human astrocytes

Glia
2018-05 | Journal article
DOI: 10.1002/glia.23302
Part of ISSN: 0894-1491
Source: Self-asserted source
Till S. Zimmer

Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment

Scientific Reports
2017-12 | Journal article
DOI: 10.1038/s41598-017-06145-8
Part of ISSN: 2045-2322
Source: Self-asserted source
Till S. Zimmer

Expression Analysis of CB2-GFP BAC Transgenic Mice

PLOS ONE
2015-09-25 | Journal article
DOI: 10.1371/journal.pone.0138986
Part of ISSN: 1932-6203
Source: Self-asserted source
Till S. Zimmer
How many people are using ORCID?