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Works (28)

Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes

Proceedings of the National Academy of Sciences
2023-09-05 | Journal article
DOI: 10.1073/pnas.2302720120
Contributors: Yann Le Guen; Guo Luo; Aditya Ambati; Vincent Damotte; Iris Jansen; Eric Yu; Aude Nicolas; Itziar de Rojas; Thiago Peixoto Leal; Akinori Miyashita et al.
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Crossref

Challenges at the APOE locus: A robust quality control approach for accurate APOE genotyping

2021-10-26 | Other
DOI: 10.1101/2021.10.19.21265022
Contributors: Michael E. Belloy; Sarah J. Eger; Yann Le Guen; Vincent Damotte; Shahzad Ahmad; M. Arfan Ikram; Alfredo Ramirez; Anthoula C. Tsolaki; Giacomina Rossi; Iris E. Jansen et al.
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Crossref

New insights on the genetic etiology of Alzheimer’s and related dementia

2020-10 | Preprint
DOI: 10.1101/2020.10.01.20200659
OTHER-ID:

PPR221611
Contributors: Bellenguez C; Küçükali F; Jansen I; Andrade V; Moreno-Grau S; Amin N; Naj AC; Grenier-Boley B; Campos-Martin R; Holmans PA et al.
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

A splice acceptor variant in HLA-DRA affects the conformation and cellular localization of the class II DR alpha-chain.

Immunology
2020-09 | Journal article
DOI: 10.1111/imm.13273
PMID: 32986852
Contributors: Didonna A; Damotte V; Shams H; Matsunaga A; Caillier SJ; Dandekar R; Misra MK; Mofrad MRK; Oksenberg JR; Hollenbach JA
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility.

Science (New York, N.Y.)
2019-09 | Journal article
DOI: 10.1126/science.aav7188
PMID: 31604244
PMC: PMC7241648
Contributors: International Multiple Sclerosis Genetics Consortium
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

Multiple Measures Reveal The Value of Both Race And Geographic Ancestry For Self-Identification

2019-07-13 | Other
DOI: 10.1101/701698
Contributors: Vincent Damotte; Chao Zhao; Chris Lin; Eric Williams; Yoram Louzoun; Abeer Madbouly; Rochelle Kotlarz; Marisa McDaniel; Paul J. Norman; Antoine Lizee et al.
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Crossref

Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk.

Cell
2019-06 | Journal article
DOI: 10.1016/j.cell.2019.06.016
PMID: 31251915
PMC: PMC6602362
Contributors: International Multiple Sclerosis Genetics Consortium. Electronic address: chris.cotsapas@yale.edu; International Multiple Sclerosis Genetics Consortium
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson’s disease

Proceedings of the National Academy of Sciences
2019-04-09 | Journal article
DOI: 10.1073/pnas.1821778116
Contributors: Jill A. Hollenbach; Paul J. Norman; Lisa E. Creary; Vincent Damotte; Gonzalo Montero-Martin; Stacy Caillier; Kirsten M. Anderson; Maneesh K. Misra; Neda Nemat-Gorgani; Kazutoyo Osoegawa et al.
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Crossref

Harnessing electronic medical records to advance research on multiple sclerosis

Multiple Sclerosis Journal
2019-03 | Journal article
DOI: 10.1177/1352458517747407
Contributors: Vincent Damotte; Antoine Lizée; Matthew Tremblay; Alisha Agrawal; Pouya Khankhanian; Adam Santaniello; Refujia Gomez; Robin Lincoln; Wendy Tang; Tiffany Chen et al.
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Crossref

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Nature genetics
2019-02 | Journal article
DOI: 10.1038/s41588-019-0358-2
PMID: 30820047
PMC: PMC6463297
Contributors: Kunkle BW; Grenier-Boley B; Sims R; Bis JC; Damotte V; Naj AC; Boland A; Vronskaya M; van der Lee SJ; Amlie-Wolf A et al.
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

pRNFL as a marker of disability worsening in the medium/long term in patients with MS.

Neurology(R) neuroimmunology & neuroinflammation
2018-12 | Journal article
DOI: 10.1212/nxi.0000000000000533
PMID: 30697584
PMC: PMC6340330
Contributors: Cordano C; Nourbakhsh B; Devereux M; Damotte V; Bennett D; Hauser SL; Cree BAC; Gelfand JM; Green AJ
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk.

Cell
2018-10 | Journal article
DOI: 10.1016/j.cell.2018.09.049
PMID: 30343897
PMC: PMC6269166
Contributors: International Multiple Sclerosis Genetics Consortium. Electronic address: chris.cotsapas@yale.edu; International Multiple Sclerosis Genetics Consortium
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

Rituximab before and during pregnancy: A systematic review, and a case series in MS and NMOSD.

Neurology(R) neuroimmunology & neuroinflammation
2018-03 | Journal article
DOI: 10.1212/nxi.0000000000000453
PMID: 29564373
PMC: PMC5858951
Contributors: Das G; Damotte V; Gelfand JM; Bevan C; Cree BAC; Do L; Green AJ; Hauser SL; Bove R
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

Electronic medical records in multiple sclerosis research

Clinical and Experimental Neuroimmunology
2018-02 | Journal article
DOI: 10.1111/cen3.12441
Contributors: Vincent Damotte; Pierre‐Antoine Gourraud
Source: check_circle
Crossref

Structure-based selection of human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis.

Genes and immunity
2018-01 | Journal article
DOI: 10.1038/s41435-017-0009-5
PMID: 29362509
PMC: PMC6054566
Contributors: Misra MK; Damotte V; Hollenbach JA
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

The immunogenetics of neurological disease.

Immunology
2017-12 | Journal article
DOI: 10.1111/imm.12869
PMID: 29159928
Contributors: Misra MK; Damotte V; Hollenbach JA
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

Plasma amyloid β levels are driven by genetic variants nearAPOE, BACE1, APP, PSEN2:A genome-wide association study in over 12,000 non-demented participants

2017-09-27 | Preprint
DOI: 10.1101/194266
Contributors: Vincent Damotte; Sven J van der Lee; Vincent Chouraki; Benjamin Grenier-Boley; Jeannette Simino; Hieab Adams; Giuseppe Tosto; Charles White; Natalie Terzikhan; Carlos Cruchaga et al.
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Crossref

Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study.

PLoS medicine
2017-03 | Journal article
DOI: 10.1371/journal.pmed.1002272
PMID: 28350795
PMC: PMC5369701
Contributors: Steele NZ; Carr JS; Bonham LW; Geier EG; Damotte V; Miller ZA; Desikan RS; Boehme KL; Mukherjee S; Crane PK et al.
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

COMT Val158Met Polymorphism Modulates Huntington's Disease Progression.

PloS one
2016-09 | Journal article
DOI: 10.1371/journal.pone.0161106
PMID: 27657697
PMC: PMC5033325
Contributors: de Diego-Balaguer R; Schramm C; Rebeix I; Dupoux E; Durr A; Brice A; Charles P; Cleret de Langavant L; Youssov K; Verny C et al.
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility.

Genes and immunity
2014-01 | Journal article
DOI: 10.1038/gene.2013.70
PMID: 24430173
Contributors: Damotte V; Guillot-Noel L; Patsopoulos NA; Madireddy L; El Behi M; International Multiple Sclerosis Genetics Consortium; Fontaine B
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

Nature genetics
2013-09 | Journal article
DOI: 10.1038/ng.2770
PMID: 24076602
PMC: PMC3832895
Contributors: International Multiple Sclerosis Genetics Consortium (IMSGC); Beecham AH; Patsopoulos NA; Xifara DK; Davis MF; Kemppinen A; Cotsapas C; Shah TS; McCauley JL
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

Genetic burden in multiple sclerosis families.

Genes and immunity
2013-08 | Journal article
DOI: 10.1038/gene.2013.37
PMID: 23903824
PMC: PMC4102601
Contributors: Isobe N; Damotte V; Re VL; Ban M; Pappas D; Guillot-Noel L; Rebeix I; Compston A; Mack T; Cozen W et al.
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis.

Brain : a journal of neurology
2013-06 | Journal article
DOI: 10.1093/brain/awt101
PMID: 23739915
PMC: PMC3673463
Contributors: International Multiple Sclerosis Genetics Consortium; Lill CM; Schjeide BM; Graetz C; Ban M; Alcina A; Ortiz MA; Pérez J; Damotte V; Booth D et al.
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

Network-based multiple sclerosis pathway analysis with GWAS data from 15,000 cases and 30,000 controls.

American journal of human genetics
2013-05 | Journal article
DOI: 10.1016/j.ajhg.2013.04.019
PMID: 23731539
PMC: PMC3958952
Contributors: International Multiple Sclerosis Genetics Consortium
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

ImmunoChip study implicates antigen presentation to T cells in narcolepsy.

PLoS genetics
2013-02 | Journal article
DOI: 10.1371/journal.pgen.1003270
PMID: 23459209
PMC: PMC3573113
Contributors: Faraco J; Lin L; Kornum BR; Kenny EE; Trynka G; Einen M; Rico TJ; Lichtner P; Dauvilliers Y; Arnulf I et al.
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

Genome-wide significant association of ANKRD55 rs6859219 and multiple sclerosis risk.

Journal of medical genetics
2013-01 | Journal article
DOI: 10.1136/jmedgenet-2012-101411
PMID: 23315543
Contributors: Lill CM; Schjeide BM; Graetz C; Liu T; Damotte V; Akkad DA; Blaschke P; Gerdes LA; Kroner A; Luessi F et al.
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

Closing the case of APOE in multiple sclerosis: no association with disease risk in over 29 000 subjects.

Journal of medical genetics
2012-09 | Journal article
DOI: 10.1136/jmedgenet-2012-101175
PMID: 22972946
Contributors: Lill CM; Liu T; Schjeide BM; Roehr JT; Akkad DA; Damotte V; Alcina A; Ortiz MA; Arroyo R; Lopez de Lapuente A et al.
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central

Determination of the real effect of genes identified in GWAS: the example of IL2RA in multiple sclerosis.

European journal of human genetics : EJHG
2011-11 | Journal article
DOI: 10.1038/ejhg.2011.197
PMID: 22085902
PMC: PMC3283173
Contributors: Babron MC; Perdry H; Handel AE; Ramagopalan SV; Damotte V; Fontaine B; Müller-Myhsok B; Ebers GC; Clerget-Darpoux F
Source: Self-asserted source
Vincent Damotte via Europe PubMed Central
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