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Keywords

organic synthesis, phytochemistry, medicinal chemistry, purines

Countries

Czech Republic

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Employment (3)

Palacký University, Olomouc: Olomouc, CZ

2021-01-01 to present | Researcher (Department of Experimental Biology)
Employment
Source: Self-asserted source
Václav Mik

Univerzita Palackého v Olomouci: Olomouc, Olomoucký, CZ

2020 to 2020-12-31 | Researcher (Laboratory of Growth Regulators)
Employment
Source: Self-asserted source
Václav Mik

Centrum Regionu Haná pro Biotechnologický a Zemědělský Výzkum: Olomouc, CZ

2014 to 2019 | Junior Researcher (Oddělení Chemické Biologie a Genetiky)
Employment
Source: Self-asserted source
Václav Mik

Works (19)

A monomer-dimer switch modulates the activity of plant adenosine kinase

2025-03-07 | Other
DOI: 10.1093/jxb/eraf094
Contributors: David Kopecny; David Jaroslav Kopecny; Armelle Vigouroux; Jakub Belicek; Martina Kopecna; Radka Koncitikova; Jaroslava Friedecka; Vaclav Mik; Klara Supikova; Jan Frantisek Humplik et al.
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Crossref

Amide conjugates of the jasmonate precursor cis-(+)-12-oxo-phytodienoic acid regulate its homeostasis during plant stress responses

Plant Physiology
2024-12-23 | Journal article
DOI: 10.1093/plphys/kiae636
Contributors: Jitka Široká; Anita Ament; Václav Mik; Tomáš Pospíšil; Michaela Kralová; Chao Zhang; Markéta Pernisová; Michal Karady; Vladimira Nožková; Yuho Nishizato et al.
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Crossref

The monomer/dimer switch modulates the activity of plant adenosine kinase

2024-12-09 | Preprint
DOI: 10.1101/2024.12.05.626941
Contributors: David Jaroslav Kopecny; Armelle Vigouroux; Jakub Belicek; Martina Kopecna; Radka Koncitikova; Jaroslava Friedecka; Vaclav Mik; Jan Frantisek Humplik; Marine Le Berre; Stephane Plancqueel et al.
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Synthetic and analytical routes to the L-amino acid conjugates of cis-OPDA and their identification and quantification in plants

Phytochemistry
2023-11 | Journal article
DOI: 10.1016/j.phytochem.2023.113855
Contributors: Václav Mik; Tomáš Pospíšil; Federica Brunoni; Jiří Grúz; Vladimíra Nožková; Claus Wasternack; Otto Miersch; Miroslav Strnad; Kristýna Floková; Ondřej Novák et al.
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A patent review of cyclin-dependent kinase 7 (CDK7) inhibitors (2018-2022)

Expert Opinion on Therapeutic Patents
2023-02 | Journal article
DOI: 10.1080/13543776.2023.2195547
Contributors: Markéta Kovalová; Joseph Peter Baraka; Václav Mik; Radek Jorda; Lei Luo; Hao Shao; Vladimír Kryštof
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Cytoprotective activities of kinetin purine isosteres

Bioorganic & Medicinal Chemistry
2021-03 | Journal article
DOI: 10.1016/j.bmc.2021.115993
Contributors: Barbara Maková; Václav Mik; Barbora Lišková; Gabriel Gonzalez; Dominik Vítek; Martina Medvedíková; Beata Monfort; Veronika Ručilová; Alena Kadlecová; Prashant Khirsariya et al.
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Crossref

Improvement of Tillering and Grain Yield by Application of Cytokinin Derivatives in Wheat and Barley

Agronomy
2020-12-30 | Journal article
DOI: 10.3390/agronomy11010067
Contributors: Radoslav Koprna; Jan F. Humplík; Zdeněk Špíšek; Magdaléna Bryksová; Marek Zatloukal; Václav Mik; Ondřej Novák; Jaroslav Nisler; Karel Doležal
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Crossref
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Cell-surface receptors enable perception of extracellular cytokinins

Nature Communications
2020-08-27 | Journal article
DOI: 10.1038/s41467-020-17700-9
Contributors: Ioanna Antoniadi; Ondřej Novák; Zuzana Gelová; Alexander Johnson; Ondřej Plíhal; Radim Simerský; Václav Mik; Thomas Vain; Eduardo Mateo-Bonmatí; Michal Karady et al.
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Cytokinin fluoroprobe reveals multiple sites of cytokinin perception at plasma membrane and endoplasmic reticulum

Nature Communications
2020-08-27 | Journal article
DOI: 10.1038/s41467-020-17949-0
Contributors: Karolina Kubiasová; Juan Carlos Montesinos; Olga Šamajová; Jaroslav Nisler; Václav Mik; Hana Semerádová; Lucie Plíhalová; Ondřej Novák; Peter Marhavý; Nicola Cavallari et al.
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Crossref

6-Substituted purines as ROCK inhibitors with anti-metastatic activity

Bioorganic Chemistry
2019-09 | Journal article
DOI: 10.1016/j.bioorg.2019.103005
Part of ISSN: 0045-2068
Source: Self-asserted source
Václav Mik

Cytokinin fluoroprobe and receptor CRE1/AHK4 localize to both plasma membrane and endoplasmic reticulum

2019-08-24 | Other
DOI: 10.1101/744177
Contributors: Karolina Kubiasová; Juan Carlos Montesinos; Olga Šamajová; Jaroslav Nisler; Václav Mik; Lucie Plíhalová; Ondřej Novák; Peter Marhavý; David Zalabák; Karel Berka et al.
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Crossref

Cell-surface receptors enable perception of extracellular cytokinins

2019-08-14 | Other
DOI: 10.1101/726125
Contributors: Ioanna Antoniadi; Ondřej Novák; Zuzana Gelová; Alexander Johnson; Ondřej Plíhal; Thomas Vain; Radim Simerský; Václav Mik; Michal Karady; Markéta Pernisová et al.
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Crossref

Design, synthesis and perception of fluorescently labeled isoprenoid cytokinins

Phytochemistry
2018-06 | Journal article
DOI: 10.1016/j.phytochem.2018.02.015
Part of ISSN: 0031-9422
Source: Self-asserted source
Václav Mik

Activity of (+)-Discadenine as a Plant Cytokinin

Journal of Natural Products
2017-07-28 | Journal article
DOI: 10.1021/acs.jnatprod.6b01165
Part of ISSN: 0163-3864
Part of ISSN: 1520-6025
Source: Self-asserted source
Václav Mik

Whole transcriptome analysis of transgenic barley with altered cytokinin homeostasis and increased tolerance to drought stress

New Biotechnology
2016-09 | Journal article
DOI: 10.1016/j.nbt.2016.01.010
Part of ISSN: 1871-6784
Source: Self-asserted source
Václav Mik

A previously undescribed jasmonate compound in flowering Arabidopsis thaliana – The identification of cis-(+)-OPDA-Ile

Phytochemistry
2016-02 | Journal article
DOI: 10.1016/j.phytochem.2015.11.012
Part of ISSN: 0031-9422
Source: Self-asserted source
Václav Mik

N9-Substituted N6-[(3-methylbut-2-en-1-yl)amino]purine derivatives and their biological activity in selected cytokinin bioassays

Bioorganic & Medicinal Chemistry
2011-12 | Journal article
DOI: 10.1016/j.bmc.2011.09.052
Part of ISSN: 0968-0896
Source: Self-asserted source
Václav Mik

N9-substituted derivatives of kinetin: Effective anti-senescence agents

Phytochemistry
2011-06 | Journal article
DOI: 10.1016/j.phytochem.2011.02.002
Part of ISSN: 0031-9422
Source: Self-asserted source
Václav Mik

Biochemical Characterization of Cytokinin Oxidases/Dehydrogenases from Arabidopsis thaliana Expressed in Nicotiana tabacum L.

Journal of Plant Growth Regulation
2007-09-18 | Journal article
DOI: 10.1007/s00344-007-9008-5
Part of ISSN: 0721-7595
Part of ISSN: 1435-8107
Source: Self-asserted source
Václav Mik
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