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Scopus Author ID: 6603754377
ResearcherID: I-7096-2016

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Employment (2)

Charles University in Prague, Faculty of Science: Praha, CZ

1984-06 to present (Biochemistry)
Employment
Source: Self-asserted source
Jiří Hudeček

Institute for Radioecology and Nuclear Research: Košice, SK

1983-09-01 to 1984-04
Employment
Source: Self-asserted source
Jiří Hudeček

Education and qualifications (1)

Charles University in Prague, Faculty of Science: Praha, CZ

1974-09 to 1978-06 | RNDr., CSc. (Physical Chemistry)
Education
Source: Self-asserted source
Jiří Hudeček

Works (50 of 62)

Items per page:
Page 1 of 2

Photo-initiated crosslinking extends mapping of the protein-protein interface to membrane-embedded portions of cytochromes P450 2B4 and b5

Methods
2015 | Journal article
DOI: 10.1016/j.ymeth.2015.07.015
EID:

2-s2.0-84946496797
Contributors: Ječmen, T.; Ptáčková, R.; Černá, V.; Dračínská, H.; Hodek, P.; Stiborová, M.; Hudeček, J.; Šulc, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Preparation and application of anti-peptide antibodies for detection of orphan cytochromes P450

Neuroendocrinology Letters
2015 | Journal article
EID:

2-s2.0-84959420473
Contributors: Hodek, P.; Hrdinova, J.; Macova, I.; Soucek, P.; Mrizova, I.; Burdova, K.; Kizek, R.; Hudecek, J.; Stiborova, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Effect of dihydromyricetin on benzo[a]pyrene activation in rats

Neuroendocrinology Letters
2014 | Journal article
EID:

2-s2.0-84928988722
Contributors: Hodek, P.; Fousova, P.; Brabencova, E.; Moserova, M.; Pavek, P.; Anzenbacherova, E.; Brotanek, J.; Hudecek, J.; Frei, E.; Stiborova, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Quantification of interactions between cytochrome P450 2B4 and cytochrome b<inf>5</inf> in a functional membrane complex

Neuroendocrinology Letters
2014 | Journal article
EID:

2-s2.0-84928995722
Contributors: Ječmen, T.; Ptáčková, R.; Kavan, D.; Cerna, V.; Hodek, P.; Stiborova, M.; Hudeček, J.; Šulc, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Optimized protocol of chicken antibody (IgY) purification providing electrophoretically homogenous preparations

International Journal of Electrochemical Science
2013 | Journal article
EID:

2-s2.0-84873878641
Contributors: Hodek, P.; Trefil, P.; Simunek, J.; Hudecek, J.; Stiborova, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Photo-cytochrome b5 - A new tool to study the cytochrome P450 electron-transport chain

International Journal of Electrochemical Science
2013 | Journal article
EID:

2-s2.0-84873866861
Contributors: Koberova, M.; Jecmen, T.; Sulc, M.; Cerna, V.; Kizek, R.; Hudecek, J.; Stiborova, M.; Hodek, P.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Structures composing protein domains

Biochimie
2013 | Journal article
DOI: 10.1016/j.biochi.2013.04.001
EID:

2-s2.0-84879686418
Contributors: Kubrycht, J.; Sigler, K.; Souček, P.; Hudeček, J.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Mapping of interaction between cytochrome P450 2B4 and cytochrome b5: The first evidence of two mutual orientations

Neuroendocrinology Letters
2012 | Journal article
EID:

2-s2.0-84874798958
Contributors: Šulc, M.; Ječmen, T.; Šnajdrová, R.; Novák, P.; Martínek, V.; Hodek, P.; Stiborová, M.; Hudeček, J.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases

Neuroendocrinology Letters
2011 | Journal article
EID:

2-s2.0-84857387612
Contributors: Martinek, V.; Kubickova, B.; Arlt, V.M.; Frei, E.; Schmeiser, H.H.; Hudecek, J.; Stiborova, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Cytochrome b5 shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy

Biochemical Pharmacology
2011 | Journal article
DOI: 10.1016/j.bcp.2011.06.003
EID:

2-s2.0-80051552143
Contributors: Kotrbová, V.; Mrázová, B.; Moserová, M.; Martínek, V.; Hodek, P.; Hudeček, J.; Frei, E.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Flexibility of human cytochrome P450 enzymes: Molecular dynamics and spectroscopy reveal important function-related variations

Biochimica et Biophysica Acta - Proteins and Proteomics
2011 | Journal article
DOI: 10.1016/j.bbapap.2010.07.017
EID:

2-s2.0-78649444586
Contributors: Hendrychová, T.; Anzenbacherová, E.; Hudeček, J.; Skopalík, J.; Lange, R.; Hildebrandt, P.; Otyepka, M.; Anzenbacher, P.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Binding of proteins to ultra high molecular weight polyethylene wear particles as a possible mechanism of macrophage and lymphocyte activation

Journal of Biomedical Materials Research - Part A
2010 | Journal article
DOI: 10.1002/jbm.a.32924
EID:

2-s2.0-78249264100
Contributors: Zolotarevová, E.; Hudeček, J.; Špundová, M.; Entlicher, G.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

3-Aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone, induces biotransformation enzymes in rat kidney and lung

Mutation Research - Genetic Toxicology and Environmental Mutagenesis
2009 | Journal article
DOI: 10.1016/j.mrgentox.2009.04.013
EID:

2-s2.0-67349090920
Contributors: Stiborová, M.; Dračínská, H.; Martínková, M.; Mizerovská, J.; Hudeček, J.; Hodek, P.; Liberda, J.; Frei, E.; Schmeiser, H.H.; Phillips, D.H. et al.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Chemopreventive compounds-View from the other side

Chemico-Biological Interactions
2009 | Journal article
DOI: 10.1016/j.cbi.2009.01.003
EID:

2-s2.0-67349092476
Contributors: Hodek, P.; Křížková, J.; Burdová, K.; Šulc, M.; Kizek, R.; Hudeček, J.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

A one-electron oxidation of carcinogenic non-aminoazo dye Sudan I by horseradish peroxidase

Neuroendocrinology Letters
2008 | Journal article
EID:

2-s2.0-57149123294
Contributors: Semanská, M.; Dračínský, M.; Martínek, V.; Hudeček, J.; Hodek, P.; Frei, E.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Human cytochromes P450 1A1 and 1A2 participate in detoxication of carcinogenic aristolochic acid

Neuroendocrinology Letters
2008 | Journal article
EID:

2-s2.0-57149122064
Contributors: Šístková, J.; Hudeček, J.; Hodek, P.; Frei, E.; Schmeiser, H.H.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Induction of cytochromes P450 in small intestine by chemopreventive compounds

Neuroendocrinology Letters
2008 | Journal article
EID:

2-s2.0-57149123819
Contributors: Křížková, J.; Burdová, K.; Hudeček, J.; Stiborová, M.; Hodek, P.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Isolation and partial characterization of the adduct formed by 13-hydroxyellipticine with deoxyguanosine in DNA

Neuroendocrinology Letters
2008 | Journal article
EID:

2-s2.0-57149128596
Contributors: Moserová, M.; Kotrbová, V.; Rupertová, M.; Naiman, K.; Hudeček, J.; Hodek, P.; Frei, E.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Macleaya cordata extract and Sangrovit genotoxicity. Assessment in vivo.

Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
2008 | Journal article
EID:

2-s2.0-56149116485
Contributors: Stiborova, M.; Vostalova, J.; Zdarilova, A.; Ulrichova, J.; Hudecek, J.; Tschirner, K.; Simanek, V.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Redox cycling in the metabolism of the environmental pollutant and suspected human carcinogen o-anisidine by rat and rabbit hepatic microsomes

Chemical Research in Toxicology
2008 | Journal article
DOI: 10.1021/tx8001127
EID:

2-s2.0-51449118603
Contributors: Naiman, K.; Dračínská, H.; Martínková, M.; Šulc, M.; Dračínský, M.; Kejíková, L.; Hodek, P.; Hudeček, J.; Liberda, J.; Schmeiser, H.H. et al.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH:Cytochrome P450 reductase null mouse

Toxicology and Applied Pharmacology
2008 | Journal article
DOI: 10.1016/j.taap.2007.09.017
EID:

2-s2.0-38649108546
Contributors: Stiborová, M.; Arlt, V.M.; Henderson, C.J.; Wolf, C.R.; Kotrbová, V.; Moserová, M.; Hudeček, J.; Phillips, D.H.; Frei, E.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Soluble recombinant CD69 receptors optimized to have an exceptional physical and chemical stability display prolonged circulation and remain intact in the blood of mice

FEBS Journal
2008 | Journal article
DOI: 10.1111/j.1742-4658.2008.06683.x
EID:

2-s2.0-54849403312
Contributors: Vaněk, O.; Nálezková, M.; Kavan, D.; Borovičková, I.; Pompach, P.; Novák, P.; Kumar, V.; Vannucci, L.; Hudeček, J.; Hofbauerová, K. et al.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Structural analysis of binding of a diamantoid substrate to cytochrome P450 2B4: Possible role of Arg 133 in modulation of function and activity of this enzyme

Neuroendocrinology Letters
2008 | Journal article
EID:

2-s2.0-57149147978
Contributors: Šulc, M.; Hudeček, J.; Stiborová, M.; Hodek, P.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity

Toxicology
2008 | Journal article
DOI: 10.1016/j.tox.2008.01.018
EID:

2-s2.0-41249085471
Contributors: Stiborová, M.; Dračínská, H.; Mizerovská, J.; Frei, E.; Schmeiser, H.H.; Hudeček, J.; Hodek, P.; Phillips, D.H.; Arlt, V.M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Comparison of the cytotoxicity of and DNA adduct formation by the anticancer drug ellipticine in human breast adenocarcinoma, leukemia and neuroblastoma cells

Chemicke Listy
2007 | Journal article
EID:

2-s2.0-38349138909
Contributors: Poljaková, J.; Frei, E.; Eckschlager, T.; Hraběta, J.; Figová, K.; Kizek, R.; Hudeček, J.; Hodek, P.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Kinetics of 3-aminobenzanthrone oxidation by rat hepatic microsomes

Chemicke Listy
2007 | Journal article
EID:

2-s2.0-38349168386
Contributors: Mizerovská, J.; Dračínská, H.; Martínková, M.; Hudeček, J.; Hodek, P.; Schmeiser, H.H.; Arlt, V.M.; Frei, E.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Kinetics of ellipticine oxidation by cytochromes p450 1a1 and 1a2 reconstituted with NADPH:cytochrome P450 reductase

Chemicke Listy
2007 | Journal article
EID:

2-s2.0-38349121291
Contributors: Mrázová, B.; Kotrbová, V.; Kořínková, M.; Svobodová, L.; Hudeček, J.; Hodek, P.; Kizek, R.; Frei, E.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Mapping of cytochrome P450 2B4 substrate binding sites by photolabile probe 3-azidiamantane: Identification of putative substrate access regions

Archives of Biochemistry and Biophysics
2007 | Journal article
DOI: 10.1016/j.abb.2007.09.017
EID:

2-s2.0-36048953952
Contributors: Hodek, P.; Karabec, M.; Šulc, M.; Sopko, B.; Smrček, S.; Martínek, V.; Hudeček, J.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Oxidation of ellipticine by human and rat cytochromes P450 correlates with its binding to DNA

Chemicke Listy
2007 | Journal article
EID:

2-s2.0-38349135664
Contributors: Martínková, E.; Hodek, P.; Hudeček, J.; Frei, E.; Dontenwill, M.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Physics and biochemistry: How much they can have in common

AIP Conference Proceedings
2007 | Conference paper
DOI: 10.1063/1.2825771
EID:

2-s2.0-71749105077
Contributors: Hudecek, J.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Reductive activation of environmental pollutants 3-nitrobenzanthrone and 2-nitrobenzanthrone

Chemicke Listy
2007 | Journal article
EID:

2-s2.0-38349100993
Contributors: Svobodová, M.; Šístková, J.; Dračínská, H.; Hudeček, J.; Hodek, P.; Schmeiser, H.H.; Arlt, V.M.; Frei, E.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Structural analysis of cytochromes P450 shows differences in flexibility of heme 2- and 4-vinyls

Biochimica et Biophysica Acta - General Subjects
2007 | Journal article
DOI: 10.1016/j.bbagen.2006.10.008
EID:

2-s2.0-33846342401
Contributors: Hudeček, J.; Hodek, P.; Anzenbacherová, E.; Anzenbacher, P.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Study of peroxidase-mediated oxidation of carcinogenic azo dye Sudan I

Chemicke Listy
2007 | Journal article
EID:

2-s2.0-38349108458
Contributors: Semanská, M.; Martínek, V.; Hudeček, J.; Hodek, P.; Dračínský, M.; Frei, E.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

The anticancer drug ellipticine is a potent inducer of rat cytochromes P450 1A1 and 1A2, thereby modulating its own metabolism

Drug Metabolism and Disposition
2007 | Journal article
DOI: 10.1124/dmd.107.016048
EID:

2-s2.0-34748888569
Contributors: Aimová, D.; Svobodová, L.; Kotrbová, V.; Mrázová, B.; Hodek, P.; Hudeček, J.; Václavíková, R.; Frei, E.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

The anticancer drug ellipticine is an inducer of rat NAD(P)H:quinone oxidoreductase

Collection of Czechoslovak Chemical Communications
2007 | Journal article
DOI: 10.1135/cccc20071350
EID:

2-s2.0-38749143636
Contributors: Stiborová, M.; Dračínská, H.; Aimová, D.; Hodek, P.; Hudeček, J.; Ryšlavá, H.; Schmeiser, H.H.; Frei, E.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Use of photoaffinity labeling for study of cytochromes P450, toxicologically important enzymes

Chemicke Listy
2007 | Journal article
EID:

2-s2.0-38349117212
Contributors: Hodek, P.; Krausová, M.; Šulc, M.; Sopko, B.; Turek, M.; Hudeček, J.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Oxidation pattern of the anticancer drug ellipticine by hepatic microsomes - Similarity between human and rat systems

General Physiology and Biophysics
2006 | Journal article
EID:

2-s2.0-33845240192
Contributors: Stiborová, M.; Bořek-Dohalská, L.; Aimová, D.; Kotrbová, V.; Kukačková, K.; Janouchová, K.; Rupertová, M.; Ryšlavá, H.; Hudeček, J.; Frei, E.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

The effect of pH on peroxidase-mediated oxidation of and DNA adduct formation by ellipticine

Collection of Czechoslovak Chemical Communications
2006 | Journal article
DOI: 10.1135/cccc20061169
EID:

2-s2.0-33748927142
Contributors: Poljaková, J.; Dračínský, M.; Frei, E.; Hudeček, J.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Active sites of two orthologous cytochromes P450 2E1: Differences revealed by spectroscopic methods

Biochemical and Biophysical Research Communications
2005 | Journal article
DOI: 10.1016/j.bbrc.2005.08.063
EID:

2-s2.0-27544486738
Contributors: Anzenbacherova, E.; Hudecek, J.; Murgida, D.; Hildebrandt, P.; Marchal, S.; Lange, R.; Anzenbacher, P.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Structural requirements for inhibitors of cytochromes P450 2B: Assessment of the enzyme interaction with diamondoids

Journal of Enzyme Inhibition and Medicinal Chemistry
2005 | Journal article
DOI: 10.1080/14756360400024324
EID:

2-s2.0-17144383651
Contributors: Hodek, P.; Bořek-Dohalská, L.; Sopko, B.; Šulc, M.; Smrček, S.; Hudeček, J.; Janků, J.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

The binding of aristolochic acid I to the active site of human cytochromes P450 1A1 and 1A2 explains their potential to reductively activate this human carcinogen

Cancer Letters
2005 | Journal article
DOI: 10.1016/j.canlet.2005.06.038
EID:

2-s2.0-26444446947
Contributors: Stiborová, M.; Sopko, B.; Hodek, P.; Frei, E.; Schmeiser, H.H.; Hudeček, J.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Chicken egg yolk as an excellent source of highly specific antibodies against cytochromes P450

Collection of Czechoslovak Chemical Communications
2004 | Journal article
DOI: 10.1135/cccc20040659
EID:

2-s2.0-1942454374
Contributors: Hodek, P.; Koblas, T.; Rýdlová, H.; Kubíčková, B.; Šulc, M.; Hudeček, J.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Study of enzymes metabolizing environmental pollutants as a means of modulating their biodegradation | Enzymy metabolizující kontaminanty životního prostředí

Chemicke Listy
2004 | Journal article
EID:

2-s2.0-8844286849
Contributors: Stiborová, M.; Hudeček, J.; Páca Jr., J.; Martínek, V.; Páca, J.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N2-oxide

Cancer Research
2004 | Journal article
DOI: 10.1158/0008-5472.CAN-04-2202
EID:

2-s2.0-8644288137
Contributors: Stiborová, M.; Sejbal, J.; Bořek-Dohalská, L.; Aimová, D.; Poljaková, J.; Forsterová, K.; Rupertová, M.; Wiesner, J.; Hudeček, J.; Wiessler, M. et al.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Hydrophobic/hydrophilic interactions of cytochrome c with functionalized self-assembled monolayers on silicon

Surface Science
2003 | Journal article
DOI: 10.1016/S0039-6028(03)00108-0
EID:

2-s2.0-0038521739
Contributors: Moré, S.D.; Hudecek, J.; Urisu, T.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Coumarin 6, hypericin, resorufins, and flavins: Suitable chromophores for fluorescence correlation spectroscopy of biological molecules

Collection of Czechoslovak Chemical Communications
2001 | Journal article
DOI: 10.1135/cccc20010855
EID:

2-s2.0-0035598507
Contributors: Beneš, M.; Hudeček, J.; Anzenbacher, P.; Hof, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Differences in flexibility of active sites of cytochromes P450 probed by resonance Raman and UV-Vis absorption spectroscopy

Journal of Inorganic Biochemistry
2001 | Journal article
DOI: 10.1016/S0162-0134(01)00389-0
EID:

2-s2.0-0035893819
Contributors: Anzenbacher, P.; Hudeček, J.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

To the mechanism of horseradish peroxidase-mediated degradation of a recalcitrant dye Remazol Brilliant blue R

Collection of Czechoslovak Chemical Communications
2001 | Journal article
DOI: 10.1135/cccc20010663
EID:

2-s2.0-0035537043
Contributors: Mikšanová, M.; Hudeček, J.; Páca, J.; Stiborová, M.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Flexibility and stability of the structure of cytochromes P450 3A4 and BM-3

European Journal of Biochemistry
2000 | Journal article
DOI: 10.1046/j.1432-1327.2000.01305.x
EID:

2-s2.0-0034077708
Contributors: Anzenbacherová, E.; Bec, N.; Anzenbacher, P.; Hudeček, J.; Souček, P.; Jung, C.; Munro, A.W.; Lange, R.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier

Structural changes in cytochrome c oxidase induced by cytochrome c binding. A resonance Raman study

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology
2000 | Journal article
DOI: 10.1016/S0167-4838(00)00103-5
EID:

2-s2.0-0343953096
Contributors: Döpner, S.; Hudecek, J.; Ludwig, B.; Witt, H.; Hildebrandt, P.
Source: Self-asserted source
Jiří Hudeček via Scopus - Elsevier
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