Personal information

Emails & domains

Verified email addresses

Websites & social links

ELIXIR

Other IDs

Scopus Author ID: 7202389339
Loop profile: 32631

Keywords

bioinformatics, molecular evolution, repetitive sequences, phenotype, ontologies, e-infrastructure

Countries

United Kingdom

Biography

During my career my interests evolved from biochemistry to bioinformatics and evolutionary biology. My interest in bioinformatics took off when I was first exposed to readily available software in the mid 1980s. A lot of my career has focussed on the evolutionary dynamics of repetitive sequences, starting with ribosomal RNAs then moving on to genomic sequences and proteins. Highlights include the discovery of compensatory slippage in RNA evolution and the association of amino acid repeats with unstructured regions of proteins. When I moved to MRC Harwell in 2002 I became interested in the relationship between genotype and phenotype with an emphasis on semantic encoding of phenotype using ontologies. Since leaving Harwell I have been engaged with science policy (at BBSRC) and bioinformatics infrastructure (in ELIXIR-UK and ELIXIR).

Activities

Collapse all

Employment (11)

University of Ljubljana: Ljubljana, SI

2020-12 to present | Visiting Professor
Employment
Source: Self-asserted source
John M. Hancock

ELIXIR: Hinxton, Cambridgeshire, GB

2017-10-30 to 2020-10-29 | Communities and Services Coordinator
Employment
Source: Self-asserted source
John M. Hancock

The Earlham Institute: Norwich, Norfolk, GB

2015-02-01 to 2017-08-31 | ELIXIR-UK Node Coordinator (Bioinformatics)
Employment
Source: Self-asserted source
John M. Hancock

BBSRC: Swindon, Wiltshire, GB

2013-05 to 2014-12-31 | Head of Strategy: Genomics, Data and Technologies
Employment
Source: Self-asserted source
John M. Hancock

MRC Mammalian Genetics Unit: Harwell, Oxfordshire, GB

2002-06 to 2012-09 | Head (Bioinformatics Group)
Employment
Source: Self-asserted source
John M. Hancock

Royal Holloway University of London: Egham, Surrey, GB

2000-03 to 2002-06 | Reader in Computational Biology (Computer Science)
Employment
Source: Self-asserted source
John M. Hancock

MRC Clinical Sciences Centre: London, London, GB

1994-09 to 2000-02 | Head (Gene & Genome Evolution)
Employment
Source: Self-asserted source
John M. Hancock

Australian National University: Canberra, ACT, AU

1991-10 to 1994-07 | Research Fellow (Research School of Biological Sciences)
Employment
Source: Self-asserted source
John M. Hancock

University of Cambridge: Cambridge, Cambridgeshire, GB

1985-12 to 1991-10 | Postdoctoral Research Associate (Genetics)
Employment
Source: Self-asserted source
John M. Hancock

Imperial College London: London, London, GB

1982-06 to 1985-09 | Postdoctoral Research Assistant (Biophysics)
Employment
Source: Self-asserted source
John M. Hancock

Max-Planck-Institut für molekulare Genetik: Berlin, Berlin, DE

1978-11 to 1982-05 | Postdoctoral Research Assistant (Wittmann)
Employment
Source: Self-asserted source
John M. Hancock

Education and qualifications (2)

University of Edinburgh: Edinburgh, Edinburgh, GB

1975-10-01 to 1980-06-01 | PhD (Genetics)
Education
Source: Self-asserted source
John M. Hancock

King's College London: London, London, GB

1972-10-01 to 1975-06-01 | BSc (Hons) Cell & Molecular Biology (Biophysics)
Education
Source: Self-asserted source
John M. Hancock

Works (50 of 127)

Items per page:
Page 1 of 3

standard-GEM: standardization of open-source genome-scale metabolic models

2023-03-23 | Preprint
DOI: 10.1101/2023.03.21.512712
Contributors: Mihail Anton; Eivind Almaas; Rui Benfeitas; Sara Benito-Vaquerizo; Lars M. Blank; Andreas Dräger; John M. Hancock; Cheewin Kittikunapong; Matthias König; Feiran Li et al.
Source: check_circle
Crossref

Systems Biology in ELIXIR: modelling in the spotlight [version 1; peer review: 1 approved, 2 approved with reservations]

2022-11-07 | Journal article
DOI: 10.12688/f1000research.126734.1
Part of ISSN: 2046-1402
Funded by GRANT_NUMBER:

MIS 5002780
Contributors: Vitor Martins dos Santos; Mihail Anton; Barbara Szomolay; Marek Ostaszewski; Ilja Arts; Rui Benfeitas; Victoria Dominguez Del Angel; Polonca Ferk; Dirk Fey; Carole Goble et al.
Source: check_circle
F1000

Matching mouse models to specific human liver disease states by comparative functional genomics of mouse and human datasets

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
2022-01 | Journal article
DOI: 10.1016/j.bbagrm.2021.194785
Part of ISSN: 1874-9399
Source: Self-asserted source
John M. Hancock

ELIXIR and Toxicology: a community in development

F1000Research
2021-11-08 | Journal article
DOI: 10.12688/f1000research.74502.1
Part of ISSN: 2046-1402
Source: Self-asserted source
John M. Hancock

ELIXIR‐EXCELERATE: establishing Europe's data infrastructure for the life science research of the future

The EMBO Journal
2021-03-15 | Journal article
DOI: 10.15252/embj.2020107409
Contributors: Jennifer Harrow; John Hancock; Niklas Blomberg; Niklas Blomberg; Søren Brunak; Salvador Capella‐Gutierrez; Christine Durinx; Chris T. Evelo; Carole Goble; Ivo Gut et al.
Source: check_circle
Crossref

The ELIXIR Human Copy Number Variations Community: building bioinformatics infrastructure for research [version 1; peer review: awaiting peer review]

2020-10-13 | Journal article
DOI: 10.12688/f1000research.24887.1
Part of ISSN: 2046-1402
Contributors: David Salgado; Irina M. Armean; Michael Baudis; Sergi Beltran; Salvador Capella-Gutierrez; Denise Carvalho-Silva; Victoria Dominguez Del Angel; Joaquin Dopazo; Laura I. Furlong; Bo Gao et al.
Source: check_circle
F1000

PlaToLoCo: the first web meta-server for visualization and annotation of low complexity regions in proteins

Nucleic Acids Research
2020-07-02 | Journal article
DOI: 10.1093/nar/gkaa339
Contributors: Patryk Jarnot; Joanna Ziemska-Legiecka; Laszlo Dobson; Matthew Merski; Pablo Mier; Miguel A Andrade-Navarro; John M Hancock; Zsuzsanna Dosztányi; Lisanna Paladin; Marco Necci et al.
Source: check_circle
Crossref

A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community) [version 1; peer review: awaiting peer review]

2020-04-22 | Journal article
DOI: 10.12688/f1000research.20559.1
Part of ISSN: 2046-1402
Contributors: Christine Orengo; Sameer Velankar; Shoshana Wodak; Vincent Zoete; Alexandre M.J.J. Bonvin; Arne Elofsson; K. Anton Feenstra; Dietland L. Gerloff; Thomas Hamelryck; John M. Hancock et al.
Source: check_circle
F1000
grade
Preferred source (of 2)‎

Studies on the Mechanism of Chromosome Banding

2020-02-24 | Other
DOI: 10.31237/osf.io/qdkte
Contributors: John Hancock
Source: check_circle
Crossref

Community curation of bioinformatics software and data resources

Briefings in Bioinformatics
2019-10-16 | Journal article
DOI: 10.1093/bib/bbz075
Part of ISSN: 1477-4054
Source: Self-asserted source
John M. Hancock

An intrinsically disordered proteins community for ELIXIR

F1000Research
2019-10-15 | Journal article
DOI: 10.12688/f1000research.20136.1
Part of ISSN: 2046-1402
Source: Self-asserted source
John M. Hancock

Disentangling the complexity of low complexity proteins.

Briefings in bioinformatics
2019-01 | Journal article
DOI: 10.1093/bib/bbz007
PMID: 30698641
Contributors: Mier P; Paladin L; Tamana S; Petrosian S; Hajdu-Soltész B; Urbanek A; Gruca A; Plewczynski D; Grynberg M; Bernadó P et al.
Source: Self-asserted source
John M. Hancock via Europe PubMed Central

BioCIDER: a Contextualisation InDEx for biological Resources discovery

Bioinformatics
2017-08-15 | Journal article
DOI: 10.1093/bioinformatics/btx213
Source: Self-asserted source
John M. Hancock

PIsCO: A Performance indicators framework for collection of bioinformatics resource metrics

PeerJ Preprints
2017-07-27 | Journal article
DOI: 10.7287/peerj.preprints.3112v1
Source: Self-asserted source
John M. Hancock
grade
Preferred source (of 2)‎

Developing a strategy for computational lab skills training through Software and Data Carpentry: Experiences from the ELIXIR Pilot action

F1000Research
2017-07-03 | Journal article
DOI: 10.12688/f1000research.11718.1
Contributors: Aleksandra Pawlik; Celia W.G. van Gelder; Aleksandra Nenadic; Patricia M. Palagi; Eija Korpelainen; Philip Lijnzaad; Diana Marek; Susanna-Assunta Sansone; John Hancock; Carole Goble
Source: check_circle
Crossref

ELIXIR-UK role in bioinformatics training at the national level and across ELIXIR

F1000Research
2017-06-21 | Journal article
DOI: 10.12688/f1000research.11837.1
Contributors: L. Larcombe; R. Hendricusdottir; T.K. Attwood; F. Bacall; N. Beard; L.J. Bellis; W.B. Dunn; J.M. Hancock; A. Nenadic; C. Orengo et al.
Source: check_circle
Crossref

Introducing the Brassica Information Portal: Towards integrating genotypic and phenotypic Brassica crop data

F1000 Research
2017-04-17 | Journal article
DOI: 10.12688/f1000research.11301.2
Source: Self-asserted source
John M. Hancock

Human Variome Project Quality Assessment Criteria for Variation Databases

Mutation Research
2016 | Journal article
PMID: 26919176
Source: Self-asserted source
John M. Hancock

An open and transparent process to select ELIXIR Node Services as implemented by ELIXIR-UK [version 1; referees: awaiting peer review]

2016-12-21 | Journal article
DOI: 10.12688/f1000research.10473.1
Contributors: John M. Hancock; Alf Game; Chris P. Ponting; Carole A. Goble
Source: check_circle
F1000

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.

2015-09 | Journal article
DOI: 10.1038/ng.3360
PMID: 26214591
Contributors: Hrabě de Angelis M; Nicholson G; Selloum M; White JK; Morgan H; Ramirez-Solis R; Sorg T; Wells S; Fuchs H; Fray M et al.
Source: Self-asserted source
John M. Hancock via Europe PubMed Central

Circles within circles: commentary on Ghosal et al. (2013) "Circ2Traits: a comprehensive database for circular RNA potentially associated with disease and traits"

Front. Genet.
2015-01-07 | Journal article
DOI: 10.3389/fgene.2014.00459
Source: Self-asserted source
John M. Hancock
grade
Preferred source (of 3)‎

Biological Ontologies and Semantic Biology

Frontiers Research Topics
2014 | Book
DOI: 10.3389/978-2-88919-277-9
Contributors: John Hancock
Source: Self-asserted source
John M. Hancock via Crossref Metadata Search

Editorial: biological ontologies and semantic biology

Front. Genet.
2014 | Journal article
DOI: 10.3389/fgene.2014.00018
Contributors: John M. Hancock
Source: Self-asserted source
John M. Hancock via Crossref Metadata Search
grade
Preferred source (of 2)‎

Commentary on Shimoyama et al. (2012): three ontologies to define phenotype measurement data

Front. Genet.
2014-04 | Journal article
DOI: 10.3389/fgene.2014.00093
Contributors: John M. Hancock
Source: Self-asserted source
John M. Hancock via Crossref Metadata Search
grade
Preferred source (of 2)‎

Phenomics

2014-01 | Book
DOI: 10.1201/b16437
Contributors: John Hancock
Source: Self-asserted source
John M. Hancock via Crossref Metadata Search

Phenomics of the Laboratory Mouse

Phenomics
2014-01 | Other
DOI: 10.1201/b16437-4
Contributors: John Hancock; Michael Dobbie
Source: Self-asserted source
John M. Hancock via Crossref Metadata Search

A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains.

2013 | Journal article
DOI: 10.1186/gb-2013-14-7-r82
PMID: 23902802
PMC: PMC4053787
Contributors: Simon MM; Greenaway S; White JK; Fuchs H; Gailus-Durner V; Wells S; Sorg T; Wong K; Bedu E; Cartwright EJ et al.
Source: Self-asserted source
John M. Hancock via Europe PubMed Central

A tale of two drug targets: the evolutionary history of BACE1 and BACE2

Front. Genet.
2013 | Journal article
DOI: 10.3389/fgene.2013.00293
Contributors: Christopher Southan; John M. Hancock
Source: Self-asserted source
John M. Hancock via Crossref Metadata Search
grade
Preferred source (of 2)‎

Functional modelling of planar cell polarity: an approach for identifying molecular function

BMC Developmental Biology
2013 | Journal article
DOI: 10.1186/1471-213x-13-20
Contributors: Lee D Hazelwood; John M Hancock
Source: Self-asserted source
John M. Hancock via Crossref Metadata Search

NucleoFinder: a statistical approach for the detection of nucleosome positions

2013 | Journal article | Author
Contributors: John M. Hancock
Source: Self-asserted source
John M. Hancock

Analyzing gene expression data in mice with the Neuro Behavior Ontology

Mamm Genome
2013-11-01 | Journal article
DOI: 10.1007/s00335-013-9481-z
Contributors: Robert Hoehndorf; John M. Hancock; Nigel W. Hardy; Ann-Marie Mallon; Paul N. Schofield; Georgios V. Gkoutos
Source: Self-asserted source
John M. Hancock via Crossref Metadata Search
grade
Preferred source (of 2)‎

Mouse Genetic and Phenotypic Resources as Tools for Human Genetics

eLS
2013-09 | Other
DOI: 10.1002/9780470015902.a0025011
Contributors: John M Hancock
Source: Self-asserted source
John M. Hancock via Crossref Metadata Search

Integration of global resources for human genetic variation and disease

Human Mutation
2012 | Journal article
DOI: 10.1002/humu.22079
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

Low microsatellite frequencies in neuron and brain expressed microRNAs

Gene
2012 | Journal article
DOI: 10.1016/j.gene.2012.07.039
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

A gene-phenotype network for the laboratory mouse and its implications for systematic phenotyping

PLoS ONE
2011 | Journal article
DOI: 10.1371/journal.pone.0019693
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

Protein coalitions in a core mammalian biochemical network linked by rapidly evolving proteins

BMC Evolutionary Biology
2011 | Journal article
DOI: 10.1186/1471-2148-11-142
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

Towards BioDBcore: A community-defined information specification for biological databases

Nucleic Acids Research
2011 | Journal article
DOI: 10.1093/nar/gkq1173
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

CASIMIR & ENFIN

2011-07-26 | Journal article
DOI: 10.1038/npre.2011.6158
Source: Self-asserted source
John M. Hancock

Finding and sharing: new approaches to registries of databases and services for the biomedical sciences.

Database : the journal of biological databases and curation
2010 | Journal article
EID: 2-s2.0-84855448103
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

Identification of a Z-band associated protein complex involving KY, FLNC and IGFN1

Experimental Cell Research
2010 | Journal article
DOI: 10.1016/j.yexcr.2010.02.027
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

Mouse Resource Browser--a database of mouse databases.

Database : the journal of biological databases and curation
2010 | Journal article
EID: 2-s2.0-84855445936
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

Phenotype ontologies for mouse and man: Bridging the semantic gap

DMM Disease Models and Mechanisms
2010 | Journal article
DOI: 10.1242/dmm.002790
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

Sustaining the data and bioresource commons

Science
2010 | Journal article
DOI: 10.1126/science.1191506
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

XGAP: A uniform and extensible data model and software platform for genotype and phenotype experiments

Genome Biology
2010 | Journal article
DOI: 10.1186/gb-2010-11-3-r27
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

Entity/quality-based logical definitions for the human skeletal phenome using PATO

Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
2009 | Journal article
DOI: 10.1109/IEMBS.2009.5333362
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

Entity/quality-based logical definitions for the human skeletal phenome using PATO.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
2009 | Journal article
EID: 2-s2.0-77951227264
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

EuroPhenome: A repository for high-throughput mouse phenotyping data

Nucleic Acids Research
2009 | Journal article
DOI: 10.1093/nar/gkp1007
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

Mouse, man, and meaning: Bridging the semantics of mouse phenotype and human disease

Mammalian Genome
2009 | Journal article
DOI: 10.1007/s00335-009-9208-3
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

MouseBook: An integrated portal of mouse resources

Nucleic Acids Research
2009 | Journal article
DOI: 10.1093/nar/gkp867
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier

Phylogenetic inference under recombination using Bayesian stochastic topology selection

Bioinformatics
2009 | Journal article
DOI: 10.1093/bioinformatics/btn607
Source: Self-asserted source
John M. Hancock via Scopus - Elsevier
Items per page:
Page 1 of 3

Peer review (16 reviews for 1 publication/grant)

Review activity for Faculty Opinions (16)
How many people are using ORCID?