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Scopus Author ID: 35227887600

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Funding (4)

Od modelu molekularnego in silico do odpowiedzi komórkowej in vitro. Modyfikowane nukleozydy jako radio- bądź/i fotosensybilizatory uszkodzeń DNA (From a molecular in silico model celluar response in vitro. Modified nucleosides as photo and/or radiosensitizers of DNA damage).

2015-04-23 to 2020-04-22 | Grant
National Science Center (Krakow, PL)
URL: https://app.dimensions.ai/details/grant/grant.4705895
GRANT_NUMBER:

2014/14/A/ST4/00405
Source: Self-asserted source
Janusz Rak via DimensionsWizard

Wpływ sekwencji nukleotydowych na wydajność radio- i fotouszkodzeń dwuniciowych fragmentów DNA znakowanych halogenopochodnymi zasad nukleinowych (Influence of nucleotide sequence on the yield of radio- and photodamage to double stranded DNA fragments labelled with the halogen derivatives of nucleobases).

2013-03-05 to 2016-03-04 | Grant
National Science Center (Krakow, PL)
URL: https://app.dimensions.ai/details/grant/grant.4712606
GRANT_NUMBER:

2012/05/B/ST5/00368
Source: Self-asserted source
Janusz Rak via DimensionsWizard

Foto- i radiouczulanie DNA przy użyciu bromopochodnych zasad nukleinowych

2011-04-13 to 2014-04-12 | Grant
Ministry of Science and Higher Education (Warsaw, PL)
URL: https://app.dimensions.ai/details/grant/grant.4706658
GRANT_NUMBER:

N N204 156040
Source: Self-asserted source
Janusz Rak via DimensionsWizard

Aniony walencyjne par zasad nukleinowych oddziałujących z łańcuchem bocznym aminokwasu. Modelowanie pierwszych etapów uszkadzania kompleksów DNA-białko niskoenergetycznymi elektronami.

2009-09-30 to 2010-10-08 | Grant
Ministry of Science and Higher Education (Warsaw, PL)
URL: https://app.dimensions.ai/details/grant/grant.4705731
GRANT_NUMBER:

N N204 125537
Source: Self-asserted source
Janusz Rak via DimensionsWizard

Works (50 of 164)

Items per page:
Page 1 of 4

Radiosensitization of PC3 Prostate Cancer Cells by 5-Thiocyanato-2′-deoxyuridine

Cancers
2022-04 | Journal article | Author
DOI: 10.3390/cancers14082035
Contributors: Magdalena Zdrowowicz; Magdalena Datta; Michał Rychłowski; Janusz Rak
Source: check_circle
Multidisciplinary Digital Publishing Institute

2,6-diaminopurine promotes repair of DNA lesions under prebiotic conditions

Nature Communications
2021-12 | Journal article
DOI: 10.1038/s41467-021-23300-y
Part of ISSN: 2041-1723
Source: Self-asserted source
Janusz Rak

Photoelectron Spectroscopy and Theoretical Investigations of Gaseous Doubly Deprotonated 2′-Deoxynucleoside 5′-Monophosphate Dianions

The Journal of Physical Chemistry Letters
2021-10-07 | Journal article
DOI: 10.1021/acs.jpclett.1c02678
Part of ISSN: 1948-7185
Part of ISSN: 1948-7185
Source: Self-asserted source
Janusz Rak

Electrophilic Properties of 2′-Deoxyadenosine···Thymine Dimer: Photoelectron Spectroscopy and DFT Studies

The Journal of Physical Chemistry A
2021-08-05 | Journal article
DOI: 10.1021/acs.jpca.1c03803
Part of ISSN: 1089-5639
Part of ISSN: 1520-5215
Source: Self-asserted source
Janusz Rak

Electron-Induced Decomposition of Uracil-5-yl <i>O-</i>(<i>N</i>,<i>N</i>-dimethylsulfamate): Role of Methylation in Molecular Stability

International Journal of Molecular Sciences
2021-02 | Journal article | Author
DOI: 10.3390/ijms22052344
Contributors: Eugene Arthur-Baidoo; Karina Falkiewicz; Lidia Chomicz-Mańka; Anna Czaja; Sebastian Demkowicz; Karol Biernacki; Witold Kozak; Janusz Rak; Stephan Denifl
Source: check_circle
Multidisciplinary Digital Publishing Institute

5-(<i>N</i>-Trifluoromethylcarboxy)aminouracil as a Potential DNA Radiosensitizer and Its Radiochemical Conversion into <i>N</i>-Uracil-5-yloxamic Acid

International Journal of Molecular Sciences
2020-09 | Journal article | Author
DOI: 10.3390/ijms21176352
Contributors: Paulina Spisz; Witold Kozak; Lidia Chomicz-Mańka; Makurat; Karina Falkiewicz; Artur Sikorski; Anna Czaja; Janusz Rak; Magdalena Zdrowowicz
Source: check_circle
Multidisciplinary Digital Publishing Institute

The Product of Matrix Metalloproteinase Cleavage of Doxorubicin Conjugate for Anticancer Drug Delivery: Calorimetric, Spectroscopic, and Molecular Dynamics Studies on Peptide–Doxorubicin Binding to DNA

International Journal of Molecular Sciences
2020-09 | Journal article | Author
DOI: 10.3390/ijms21186923
Contributors: Kamila Butowska; Krzysztof Żamojć; Mateusz Kogut; Witold Kozak; Dariusz Wyrzykowski; Wiesław Wiczk; Jacek Czub; Jacek Piosik; Janusz Rak
Source: check_circle
Multidisciplinary Digital Publishing Institute

Electron-Induced Dissociation of the Potential Radiosensitizer 5-Selenocyanato-2′-deoxyuridine

Journal of Physical Chemistry B
2019 | Journal article
DOI: 10.1021/acs.jpcb.8b11523
EID:

2-s2.0-85061708295
Contributors: Meißner, R.; Makurat, S.; Kozak, W.; Limão-Vieira, P.; Rak, J.; Denifl, S.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Photoinduced electron transfer in 5-bromouracil labeled DNA. A contrathermodynamic mechanism revisited by electron transfer theories

Physical Chemistry Chemical Physics
2019 | Journal article
DOI: 10.1039/c8cp07700b
EID:

2-s2.0-85061858224
Contributors: Cupellini, L.; Wityk, P.; Mennucci, B.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Why Does the Type of Halogen Atom Matter for the Radiosensitizing Properties of 5-Halogen Substituted 4-Thio-2'-Deoxyuridines?

Molecules (Basel, Switzerland)
2019 | Journal article
DOI: 10.3390/molecules24152819
EID:

2-s2.0-85071151314
Contributors: Spisz, P.; Zdrowowicz, M.; Makurat, S.; Kozak, W.; Skotnicki, K.; Bobrowski, K.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

5-Iodo-4-thio-2′-Deoxyuridine as a Sensitizer of X-ray Induced Cancer Cell Killing

International Journal of Molecular Sciences
2019-03 | Journal article | Author
DOI: 10.3390/ijms20061308
Contributors: Makurat; PAULINA SPISZ; Witold Kozak; Janusz Rak; Magdalena Zdrowowicz
Source: check_circle
Multidisciplinary Digital Publishing Institute
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Preferred source (of 2)‎

5-Selenocyanato and 5-trifluoromethanesulfonyl derivatives of 2′-deoxyuridine: Synthesis, radiation and computational chemistry as well as cytotoxicity

RSC Advances
2018 | Journal article
DOI: 10.1039/c8ra03172j
EID:

2-s2.0-85048805809
Contributors: Makurat, S.; Zdrowowicz, M.; Chomicz-Mańka, L.; Kozak, W.; Serdiuk, I.E.; Wityk, P.; Kawecka, A.; Sosnowska, M.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Low-energy electron-induced decomposition of 5-trifluoromethanesulfonyl-uracil: A potential radiosensitizer

Journal of Chemical Physics
2018 | Journal article
DOI: 10.1063/1.5050594
EID:

2-s2.0-85055902567
Contributors: Ameixa, J.; Arthur-Baidoo, E.; Meißner, R.; Makurat, S.; Kozak, W.; Butowska, K.; Ferreira Da Silva, F.; Rak, J.; Denifl, S.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Molecular features of thymidine analogues governing the activity of human thymidine kinase

Structural Chemistry
2018 | Journal article
DOI: 10.1007/s11224-018-1124-2
EID:

2-s2.0-85046706917
Contributors: Jagiello, K.; Makurat, S.; Pereć, S.; Rak, J.; Puzyn, T.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

5-Selenocyanatouracil: A Potential Hypoxic Radiosensitizer. Electron Attachment Induced Formation of Selenium Centered Radical

Journal of Physical Chemistry B
2017 | Journal article
DOI: 10.1021/acs.jpcb.7b03633
EID:

2-s2.0-85022225728
Contributors: Sosnowska, M.; Makurat, S.; Zdrowowicz, M.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

A study of an hypothesis linking aluminum fluoride to alzheimer disease: The affinity of amino acids occurring in Beta-amyloid to [Al(H<inf>2</inf>O)<inf>6</inf>]<sup>3+</sup>

Fluoride
2017 | Journal article
EID:

2-s2.0-85045293115
Contributors: Szyperska, A.; Gutowska, I.; Machoy-Mokrzyńska, A.; Rak, J.; Baranowska-Bosiacka, I.; Machoy, Z.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Chemically–enzymatic synthesis of photosensitive DNA

Journal of Photochemistry and Photobiology B: Biology
2017 | Journal article
DOI: 10.1016/j.jphotobiol.2017.01.005
EID:

2-s2.0-85009097051
Contributors: Westphal, K.; Zdrowowicz, M.; Zylicz-Stachula, A.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Consequences of electron attachment to modified nucleosides incorporated into DNA

Handbook of Computational Chemistry
2017 | Book
Part of DOI: 10.1007/978-3-319-27282-5_48
EID:

2-s2.0-85045961825
Contributors: Chomicz-Mańka, L.; Wityk, P.; Golon, Ł.; Zdrowowicz, M.; Wiczk, J.; Westphal, K.; Żyndul, M.; Makurat, S.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Dominant Pathways of Adenosyl Radical-Induced DNA Damage Revealed by QM/MM Metadynamics

Journal of Chemical Theory and Computation
2017 | Journal article
DOI: 10.1021/acs.jctc.7b00978
EID:

2-s2.0-85038222350
Contributors: Wityk, P.; Wieczór, M.; Makurat, S.; Chomicz-Mańka, L.; Czub, J.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

The sequence dependence of photoinduced single strand break in 5-bromo-2′-deoxyuridine labeled DNA supports that electron transfer is responsible for the damage

Journal of Physical Chemistry B
2017 | Journal article
DOI: 10.1021/acs.jpcb.7b07338
EID:

2-s2.0-85031299610
Contributors: Westphal, K.; Makurat, S.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

UV-induced electron transfer between triethylamine and 5-bromo-2′-deoxyuridine. A puzzle concerning the photochemical debromination of labeled DNA

Journal of Pharmaceutical and Biomedical Analysis
2017 | Journal article
DOI: 10.1016/j.jpba.2017.04.044
EID:

2-s2.0-85019607132
Contributors: Wityk, P.; Zdrowowicz, M.; Wiczk, J.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Visible-Light Photocatalytic Activity of Ionic Liquid TiO <inf>2</inf> Spheres: Effect of the Ionic Liquid's Anion Structure

ChemCatChem
2017 | Journal article
DOI: 10.1002/cctc.201700861
EID:

2-s2.0-85037722354
Contributors: Łuczak, J.; Paszkiewicz-Gawron, M.; Długokęcka, M.; Lisowski, W.; Grabowska, E.; Makurat, S.; Rak, J.; Zaleska-Medynska, A.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

5-Bromo-2′-deoxycytidine - A potential DNA photosensitizer

Organic and Biomolecular Chemistry
2016 | Journal article
DOI: 10.1039/c6ob01446a
EID:

2-s2.0-84990049605
Contributors: Zdrowowicz, M.; Wityk, P.; Michalska, B.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Electrophilic 5-Substituted Uracils as Potential Radiosensitizers: A Density Functional Theory Study

ChemPhysChem
2016 | Journal article
DOI: 10.1002/cphc.201600240
EID:

2-s2.0-84983087515
Contributors: Makurat, S.; Chomicz-Mańka, L.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Excess Electron Attachment to the Nucleoside Pair 2′-Deoxyadenosine (dA)-2′-Deoxythymidine (dT)

Journal of Physical Chemistry B
2016 | Journal article
DOI: 10.1021/acs.jpcb.6b03450
EID:

2-s2.0-84974539659
Contributors: Storoniak, P.; Rak, J.; Ko, Y.J.; Wang, H.; Bowen, K.H.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Quantitative assay of photoinduced DNA strand breaks by real-time PCR

Journal of Pharmaceutical and Biomedical Analysis
2016 | Journal article
DOI: 10.1016/j.jpba.2016.06.023
EID:

2-s2.0-84976574444
Contributors: Wiczk, J.; Westphal, K.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Radiation damage to single stranded oligonucleotide trimers labelled with 5-iodopyrimidines

Organic and Biomolecular Chemistry
2016 | Journal article
DOI: 10.1039/c6ob01713d
EID:

2-s2.0-84990188308
Contributors: Westphal, K.; Skotnicki, K.; Bobrowski, K.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

5-Thiocyanato-2′-deoxyuridine as a possible radiosensitizer: electron-induced formation of uracil-C5-thiyl radical and its dimerization

Physical Chemistry Chemical Physics
2015 | Journal article
DOI: 10.1039/c5cp02081f
EID:

2-s2.0-84933074380
Contributors: Zdrowowicz, M.; Chomicz, L.; Zyndul, M.; Wityk, P.; Rak, J.; Wiegand, T.J.; Hanson, C.G.; Adhikary, A.; Sevilla, M.D.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Irreversible electron attachment-a key to DNA damage by solvated electrons in aqueous solution

Organic and Biomolecular Chemistry
2015 | Journal article
DOI: 10.1039/c5ob01542a
EID:

2-s2.0-84944266528
Contributors: Westphal, K.; Wiczk, J.; Miloch, J.; Kciuk, G.; Bobrowski, K.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Mechanisms of Damage to DNA Labeled with Electrophilic Nucleobases Induced by Ionizing or UV Radiation

Journal of Physical Chemistry B
2015 | Journal article
DOI: 10.1021/acs.jpcb.5b03948
EID:

2-s2.0-84944197323
Contributors: Rak, J.; Chomicz, L.; Wiczk, J.; Westphal, K.; Zdrowowicz, M.; Wityk, P.; Zyndul, M.; Makurat, S.; Golon, Ł.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Reactivity pattern of bromonucleosides induced by 2-hydroxypropyl radicals: Photochemical, radiation chemical, and computational studies

Journal of Physical Chemistry B
2015 | Journal article
DOI: 10.1021/acs.jpcb.5b01904
EID:

2-s2.0-84930960275
Contributors: Zdrowowicz, M.; Chomicz, L.; Miloch, J.; Wiczk, J.; Rak, J.; Kciuk, G.; Bobrowski, K.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

A first-principles study of electron attachment to the fully hydrated bromonucleobases

Chemical Physics Letters
2014 | Journal article
DOI: 10.1016/j.cplett.2014.01.052
EID:

2-s2.0-84894698889
Contributors: Wieczór, M.; Wityk, P.; Czub, J.; Chomicz, L.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

An ESR and DFT study of hydration of the 2′-deoxyuridine-5-yl radical: A possible hydroxyl radical intermediate

Chemical Communications
2014 | Journal article
DOI: 10.1039/c4cc07089e
EID:

2-s2.0-84908681078
Contributors: Chomicz, L.; Petrovici, A.; Archbold, I.; Adhikary, A.; Kumar, A.; Sevilla, M.D.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Artificial plasmid labeled with 5-bromo-2′-deoxyuridine: A universal molecular system for strand break detection

ChemBioChem
2014 | Journal article
DOI: 10.1002/cbic.201402082
EID:

2-s2.0-84903697289
Contributors: Zylicz-Stachula, A.; Polska, K.; Skowron, P.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

DHPLC and MS studies of a photoinduced intrastrand cross-link in DNA labeled with 5-bromo-2′-deoxyuridine

Journal of Photochemistry and Photobiology B: Biology
2014 | Journal article
DOI: 10.1016/j.jphotobiol.2013.11.004
EID:

2-s2.0-84889259902
Contributors: Wiczk, J.; Miloch, J.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Electron induced single strand break and cyclization: A DFT study on the radiosensitization mechanism of the nucleotide of 8-bromoguanine

Physical Chemistry Chemical Physics
2014 | Journal article
DOI: 10.1039/c3cp55411b
EID:

2-s2.0-84896369621
Contributors: Chomicz, L.; Furmanchuk, A.; Leszczynski, J.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Electron-induced single strand break in the nucleotide of 5- and 6-bromouridine. A DFT study

Chemical Physics Letters
2014 | Journal article
DOI: 10.1016/j.cplett.2014.08.049
EID:

2-s2.0-84906966578
Contributors: Golon, Ł.; Chomicz, L.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Photoinduced single strand breaks and intrastrand cross-links in an oligonucleotide labeled with 5-bromouracil

Journal of Physical Chemistry B
2014 | Journal article
DOI: 10.1021/jp500192z
EID:

2-s2.0-84900541178
Contributors: Zdrowowicz, M.; Michalska, B.; Zylicz-Stachula, A.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Synthesis, redox properties, and basicity of substituted 1-aminoanthraquinones: Spectroscopic, electrochemical, and computational studies in acetonitrile solutions

Structural Chemistry
2014 | Journal article
DOI: 10.1007/s11224-013-0332-z
EID:

2-s2.0-84962336505
Contributors: Zarzeczańska, D.; Niedziałkowski, P.; Wcisło, A.; Chomicz, L.; Rak, J.; Ossowski, T.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

The radiosensitivity of 5- and 6-bromocytidine derivatives-electron induced DNA degradation

Physical Chemistry Chemical Physics
2014 | Journal article
DOI: 10.1039/c4cp03139c
EID:

2-s2.0-84906545649
Contributors: Chomicz, L.; Golon, Ł.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Electron-induced degradation of 8-bromo-2′-deoxyadenosine 3′,5′-diphosphate, a DNA radiosensitizing nucleotide

Journal of Physical Chemistry B
2013 | Journal article
DOI: 10.1021/jp4022689
EID:

2-s2.0-84961983279
Contributors: Chomicz, L.; Leszczynski, J.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

How to find out whether a 5-substituted uracil could be a potential DNA radiosensitizer

Journal of Physical Chemistry Letters
2013 | Journal article
DOI: 10.1021/jz401358w
EID:

2-s2.0-84962376584
Contributors: Chomicz, L.; Zdrowowicz, M.; Kasprzykowski, F.; Rak, J.; Buonaugurio, A.; Wang, Y.; Bowen, K.H.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Photoelectron spectroscopic and density functional theoretical studies of the 2′-deoxycytidine homodimer radical anion

Journal of Chemical Physics
2013 | Journal article
DOI: 10.1063/1.4817779
EID:

2-s2.0-84903363926
Contributors: Storoniak, P.; Rak, J.; Ko, Y.J.; Wang, H.; Bowen, K.H.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Presolvated low energy electron attachment to peptide methyl esters in aqueous solution: C-O bond cleavage at 77 K

Journal of Physical Chemistry B
2013 | Journal article
DOI: 10.1021/jp400176c
EID:

2-s2.0-84875196328
Contributors: Kheir, J.; Chomicz, L.; Engle, A.; Rak, J.; Sevilla, M.D.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

UV-induced strand breaks in double-stranded DNA labeled with 5-bromouracil: Frank or secondary?

Journal of Physical Chemistry Letters
2013 | Journal article
DOI: 10.1021/jz402208z
EID:

2-s2.0-84888389032
Contributors: Wiczk, J.; Miloch, J.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Electron stimulated desorption of anions from native and brominated single stranded oligonucleotide trimers

Journal of Chemical Physics
2012 | Journal article
DOI: 10.1063/1.3685587
EID:

2-s2.0-84857517987
Contributors: Polska, K.; Rak, J.; Bass, A.D.; Cloutier, P.; Sanche, L.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Electron-induced elimination of the bromide anion from brominated nucleobases. A computational study

Journal of Physical Chemistry B
2012 | Journal article
DOI: 10.1021/jp3008738
EID:

2-s2.0-84862094793
Contributors: Chomicz, L.; Rak, J.; Storoniak, P.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Fundamental mechanisms of DNA radiosensitization: Damage induced by low-energy electrons in brominated oligonucleotide trimers

Journal of Physical Chemistry B
2012 | Journal article
DOI: 10.1021/jp304964r
EID:

2-s2.0-84865124447
Contributors: Park, Y.; Polska, K.; Rak, J.; Wagner, J.R.; Sanche, L.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Photoelectron spectroscopy and computational modeling of thymidine homodimer anions

Journal of Physical Chemistry B
2012 | Journal article
DOI: 10.1021/jp307570p
EID:

2-s2.0-84870778690
Contributors: Storoniak, P.; Rak, J.; Ko, Y.J.; Wang, H.; Bowen, K.H.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier

Photoelectron spectroscopy and density functional theory studies on the uridine homodimer radical anions

Journal of Chemical Physics
2012 | Journal article
DOI: 10.1063/1.4767053
EID:

2-s2.0-84877156507
Contributors: Jae Ko, Y.; Storoniak, P.; Wang, H.; Bowen, K.H.; Rak, J.
Source: Self-asserted source
Janusz Rak via Scopus - Elsevier
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