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Biography
My research career started as a research assistant in IPMB and learned basic molecular biology techniques (1986). My PhD work is focused on regulatory sequences for two classes of potato sucrose synthase genes finding the important regulatory roles of their long leader introns (1995). I started to work on plant ubiquitin proteasome field as a postdoc and started to functionally annotate all proteasome subunits and identified the first binding site on RPN10 for the ubiquitinated proteasome substrates (1998). After joining IPMB, I continued to work on and complete the functional annotation of all proteasome subunits. I then started to map subunit interactions of the 26S proteasome and to characterize major ubiquitin receptors biochemically and functionally and extend my studies to the recently identified OTU deubiquitinases focusing on OTU5 and a K11 linkage-specific E2 UBC22.