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Works (24)

Hypothalamic deep brain stimulation augments walking after spinal cord injury

Nature Medicine
2024-12 | Journal article
DOI: 10.1038/s41591-024-03306-x
Contributors: Newton Cho; Jordan W. Squair; Viviana Aureli; Nicholas D. James; Léa Bole-Feysot; Inssia Dewany; Nicolas Hankov; Laetitia Baud; Anna Leonhartsberger; Kristina Sveistyte et al.
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Single-cell and spatial atlases of spinal cord injury in the Tabulae Paralytica

Nature
2024-07-04 | Journal article
DOI: 10.1038/s41586-024-07504-y
Contributors: Michael A. Skinnider; Matthieu Gautier; Alan Yue Yang Teo; Claudia Kathe; Thomas H. Hutson; Achilleas Laskaratos; Alexandra de Coucy; Nicola Regazzi; Viviana Aureli; Nicholas D. James et al.
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Recovery of walking after paralysis by regenerating characterized neurons to their natural target region

Science
2023-09-22 | Journal article
DOI: 10.1126/science.adi6412
Contributors: Jordan W. Squair; Marco Milano; Alexandra de Coucy; Matthieu Gautier; Michael A. Skinnider; Nicholas D. James; Newton Cho; Anna Lasne; Claudia Kathe; Thomas H. Hutson et al.
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Unbiased Interrogation of Whole Brain Circuits Identifies Neurons That Restore Walking After Spinal Cord Injury

Neurosurgery
2022 | Journal article
WOSUID: WOS:000783218700100
Contributors: Cho, Newton; Squair, Jordan W.; James, Nicholas; Baud, Laetitia; Leonhartsberger, Anna; Sveistyte, Kristina; Galan, Katia; Barraud, Quentin; Goubran, Maged; Batti, Laura et al.
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The neurons that restore walking after paralysis

Nature
2022-11-17 | Journal article
DOI: 10.1038/s41586-022-05385-7
Contributors: Claudia Kathe; Michael A. Skinnider; Thomas H. Hutson; Nicola Regazzi; Matthieu Gautier; Robin Demesmaeker; Salif Komi; Steven Ceto; Nicholas D. James; Newton Cho et al.
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Epidural electrical stimulation of the cervical dorsal roots restores voluntary upper limb control in paralyzed monkeys

Nature Neuroscience
2022-07 | Journal article
DOI: 10.1038/s41593-022-01106-5
Contributors: Beatrice Barra; Sara Conti; Matthew G. Perich; Katie Zhuang; Giuseppe Schiavone; Florian Fallegger; Katia Galan; Nicholas D. James; Quentin Barraud; Maude Delacombaz et al.
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Preclinical upper limb neurorobotic platform to assess, rehabilitate, and develop therapies

Science Robotics
2022-03-30 | Journal article
DOI: 10.1126/scirobotics.abk2378
Contributors: Maria Pasquini; Nicholas D. James; Inssia Dewany; Florent-Valéry Coen; Newton Cho; Stefano Lai; Selin Anil; Jacopo Carpaneto; Quentin Barraud; Stéphanie P. Lacour et al.
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Combined treatment with enteric neural stem cells and chondroitinase ABC reduces spinal cord lesion pathology

Stem Cell Research & Therapy
2021 | Journal article
DOI: 10.1186/S13287-020-02031-9
WOSUID: WOS:000610174700009
Contributors: Jevans, Benjamin; James, Nicholas D.; Burnside, Emily; McCann, Conor J.; Thapar, Nikhil; Bradbury, Elizabeth J.; Burns, Alan J.
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Confronting false discoveries in single-cell differential expression

Nature Communications
2021 | Journal article
DOI: 10.1038/S41467-021-25960-2
WOSUID: WOS:000701980200007
Contributors: Squair, Jordan W.; Gautier, Matthieu; Kathe, Claudia; Anderson, Mark A.; James, Nicholas D.; Hutson, Thomas H.; Hudelle, Remi; Qaiser, Taha; Matson, Kaya J. E.; Barraud, Quentin et al.
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Multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury

Nature Communications
2021 | Journal article
DOI: 10.1038/S41467-021-22137-9
WOSUID: WOS:000635230100029
Contributors: Bonizzato, Marco; James, Nicholas D.; Pidpruzhnykova, Galyna; Pavlova, Natalia; Shkorbatova, Polina; Baud, Laetitia; Martinez-Gonzalez, Cristina; Squair, Jordan W.; DiGiovanna, Jack; Barraud, Quentin et al.
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Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury

Nature
2021 | Journal article
DOI: 10.1038/S41586-020-03180-W
WOSUID: WOS:000612726300013
Contributors: Squair, Jordan W.; Gautier, Matthieu; Mahe, Lois; Soriano, Jan Elaine; Rowald, Andreas; Bichat, Arnaud; Cho, Newton; Anderson, Mark A.; James, Nicholas D.; Gandar, Jerome et al.
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Recruitment of upper-limb motoneurons with epidural electrical stimulation of the cervical spinal cord

Nature Communications
2021 | Journal article
DOI: 10.1038/S41467-020-20703-1
WOSUID: WOS:000613518600003
Contributors: Greiner, Nathan; Barra, Beatrice; Schiavone, Giuseppe; Lorach, Henri; James, Nicholas; Conti, Sara; Kaeser, Melanie; Fallegger, Florian; Borgognon, Simon; Lacour, Stephanie et al.
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Structured nanoscale metallic glass fibres with extreme aspect ratios

Nature Nanotechnology
2020 | Journal article
DOI: 10.1038/S41565-020-0747-9
WOSUID: WOS:000555383200003
Contributors: Yan, Wei; Richard, Ines; Kurtuldu, Gueven; James, Nicholas D.; Schiavone, Giuseppe; Squair, Jordan W.; Nguyen-Dang, Tung; Das Gupta, Tapajyoti; Qu, Yunpeng; Cao, Jake D. et al.
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ErbB receptor signaling directly controls oligodendrocyte progenitor cell transformation and spontaneous remyelination after spinal cord injury

Glia
2019 | Journal article
DOI: 10.1002/GLIA.23586
WOSUID: WOS:000465353800002
Contributors: Bartus, Katalin; Burnside, Emily R.; Galino, Jorge; James, Nicholas D.; Bennett, David L. H.; Bradbury, Elizabeth J.
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Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury

Brain
2018 | Journal article
DOI: 10.1093/BRAIN/AWY158
WOSUID: WOS:000440991100023
Contributors: Burnside, Emily R.; De Winter, Fred; Didangelos, Athanasios; James, Nicholas D.; Andreica, Elena-Cristina; Layard-Horsfall, Hugo; Muir, Elizabeth M.; Verhaagen, Joost; Bradbury, Elizabeth J.
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Neuromodulation in the restoration of function after spinal cord injury

The Lancet Neurology
2018 | Journal article
DOI: 10.1016/S1474-4422(18)30287-4
WOSUID: WOS:000444862200018
Contributors: James, Nicholas D.; McMahon, Stephen B.; Field-Fote, Edelle C.; Bradbury, Elizabeth J.
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Required growth facilitators propel axon regeneration across complete spinal cord injury

Nature
2018 | Journal article
DOI: 10.1038/S41586-018-0467-6
WOSUID: WOS:000445011500055
Contributors: Anderson, Mark A.; O'Shea, Timothy M.; Burda, Joshua E.; Ao, Yan; Barlatey, Sabry L.; Bernstein, Alexander M.; Kim, Jae H.; James, Nicholas D.; Rogers, Alexandra; Kato, Brian et al.
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Structural and Functional Substitution of Deleted Primary Sensory Neurons by New Growth from Intrinsic Spinal Cord Nerve Cells: An Alternative Concept in Reconstruction of Spinal Cord Circuits

Frontiers in Neurology
2017 | Journal article
DOI: 10.3389/FNEUR.2017.00358
WOSUID: WOS:000406487200001
Contributors: James, Nicholas D.; Angeria, Maria; Bradbury, Elizabeth J.; Damberg, Peter; McMahon, Stephen B.; Risling, Marten; Carlstedt, Thomas
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Surgical reconstruction of spinal cord circuit provides functional return in humans

Neural Regeneration Research
2017 | Journal article
DOI: 10.4103/1673-5374.221145
WOSUID: WOS:000422615700004
Contributors: Carlstedt, Thomas; James, Nicholas; Risling, Marten
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Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury

Brain
2016 | Journal article
DOI: 10.1093/BRAIN/AWW039
WOSUID: WOS:000376107200012
Contributors: Bartus, Katalin; Galino, Jorge; James, Nicholas D.; Hernandez-Miranda, Luis R.; Dawes, John M.; Fricker, Florence R.; Garratt, Alistair N.; McMahon, Stephen B.; Ramer, Matt S.; Birchmeier, Carmen et al.
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Chondroitinase gene therapy improves upper limb function following cervical contusion injury

Experimental Neurology
2015 | Journal article
DOI: 10.1016/J.EXPNEUROL.2015.05.022
WOSUID: WOS:000362627200014
Contributors: James, Nicholas D.; Shea, Jessie; Muir, Elizabeth M.; Verhaagen, Joost; Schneider, Bernard L.; Bradbury, Elizabeth J.
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Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury

The Journal of Neuroscience
2014 | Journal article
DOI: 10.1523/JNEUROSCI.4369-13.2014
WOSUID: WOS:000334076000008
Contributors: Bartus, Katalin; James, Nicholas D.; Didangelos, Athanasios; Bosch, Karen D.; Verhaagen, Joost; Yanez-Munoz, Rafael J.; Rogers, John H.; Schneider, Bernard L.; Muir, Elizabeth M.; Bradbury, Elizabeth J.
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Chondroitin sulphate proteoglycans: Key modulators of spinal cord and brain plasticity

Experimental Neurology
2012 | Journal article
DOI: 10.1016/J.EXPNEUROL.2011.08.008
WOSUID: WOS:000303430400001
Contributors: Bartus, K.; James, N. D.; Bosch, K. D.; Bradbury, E. J.
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Conduction Failure following Spinal Cord Injury: Functional and Anatomical Changes from Acute to Chronic Stages

The Journal of Neuroscience
2011 | Journal article
DOI: 10.1523/JNEUROSCI.4306-11.2011
WOSUID: WOS:000298055600029
Contributors: James, Nicholas D.; Bartus, Katalin; Grist, John; Bennett, David L. H.; McMahon, Stephen B.; Bradbury, Elizabeth J.
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