Personal information

Other IDs

ResearcherID: G-7578-2015

Keywords

Parasitology, Proteomics, Posttranslational modifications, Malaria, Toxoplasma, Epigenetics, Proteases

Countries

United States

Biography

Natalie Silmon de Monerri MBiol PhD obtained her undergraduate degree at the University of Bath, where she studied towards an integrated Masters of Biology degree in Molecular and Cellular Biology. She went on to study the importance of proteases and perforin-like proteins in malaria parasite egress from infected erythrocytes at the MRC National Institute for Medical Research and was awarded her PhD from University College London in 2010. She conducted her postdoctoral training in the United States at Albert Einstein College of Medicine, where she is currently a 4th year research fellow. There, she studies the function of posttranslational modifications in transcriptional and epigenetic control in the protozoan parasite Toxoplasma gondii, using a combination of proteomics, genome-wide studies and classical molecular genetics techniques.

Dr. Silmon de Monerri is an expert in microbiology and parasitology. She has specific expertise in molecular parasitology of Plasmodium falciparum and Toxoplasma gondii, and other Apicomplexan parasites. She has extensive experience in proteomics of posttranslational modifications including identification of protease substrates and mapping of posttranslational modifications.

Activities

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Employment (4)

Pfizer Global Research and Development: Pearl River, NY, US

2017-02-24 to present | Director (Vaccines R&D)
Employment
Source: Self-asserted source
Natalie Silmon de Monerri

Yeshiva University Albert Einstein College of Medicine: Bronx, NY, US

2011-09 to 2017-02-10 | Research Fellow (Pathology)
Employment
Source: Self-asserted source
Natalie Silmon de Monerri

National Institute for Medical Research: London, London, GB

2010 to 2011 | Postdoctoral Research Assistant (Parasitology)
Employment
Source: Self-asserted source
Natalie Silmon de Monerri

Merck KGaA: Darmstadt, Hessen, DE

2005-08 to 2006-08 | Placement student (R&D)
Employment
Source: Self-asserted source
Natalie Silmon de Monerri

Education and qualifications (2)

National Institute for Medical Research: London, London, GB

2007-09-24 to 2010-11-10 | PhD (Parasitology)
Education
Source: Self-asserted source
Natalie Silmon de Monerri

University of Bath: Bath, Bath and North East Somer, GB

2003-09 to 2007-06 | MBiol Molecular and Cellular Biology (Biology and Biochemistry)
Education
Source: Self-asserted source
Natalie Silmon de Monerri

Works (8)

Structure-based design of an immunogenic, conformationally stabilized FimH antigen for a urinary tract infection vaccine

PLOS Pathogens
2025-02-19 | Journal article
DOI: 10.1371/journal.ppat.1012325
Contributors: Natalie C. Silmon de Monerri; Matthew A Mulvey; Ye Che; Joshua A. Lees; Jayasankar Jasti; Huixian Wu; Matthew C. Griffor; Srinivas Kodali; Julio Cesar Hawkins; Jacqueline Lypowy et al.
Source: check_circle
Crossref

Structure-Based Design of a Highly Immunogenic, Conformationally Stabilized FimH Antigen for a Urinary Tract Infection Vaccine

2024-06-10 | Preprint
DOI: 10.1101/2024.06.10.598184
Contributors: Natalie C. Silmon de Monerri; Ye Che; Joshua A. Lees; Jayasankar Jasti; Huixian Wu; Matthew C. Griffor; Srinivas Kodali; Julio Caesar Hawkins; Jacqueline Lypowy; Christopher Ponce et al.
Source: check_circle
Crossref

Integration of RNA-seq and proteomics data with genomics for improved genome annotation in Apicomplexan Parasites

Proteomics
2015-07 | Journal article
DOI: 10.1002/pmic.201500253
Contributors: Natalie C. Silmon de Monerri; Louis M. Weiss
Source: Self-asserted source
Natalie Silmon de Monerri via Crossref Metadata Search

Pathogens Hijack the Epigenome

The American Journal of Pathology
2014-04 | Journal article
DOI:

10.1016/j.ajpath.2013.12.022
Contributors: Natalie C. Silmon de Monerri; Kami Kim
Source: Self-asserted source
Natalie Silmon de Monerri via Crossref Metadata Search

Plasmodium Subtilisins

Handbook of Proteolytic Enzymes
2013 | Other
DOI:

10.1016/b978-0-12-382219-2.00720-1
Contributors: Natalie C. Silmon de Monerri; Andrea Ruecker; Michael J. Blackman
Source: Self-asserted source
Natalie Silmon de Monerri via Crossref Metadata Search

The Histone Code of Toxoplasma gondii Comprises Conserved and Unique Posttranslational Modifications

mBio
2013-10 | Journal article
DOI:

10.1128/mbio.00922-13
Contributors: S. C. Nardelli; F.-Y. Che; N. C. Silmon de Monerri; H. Xiao; E. Nieves; C. Madrid-Aliste; S. O. Angel; W. J. Sullivan; R. H. Angeletti; K. Kim et al.
Source: Self-asserted source
Natalie Silmon de Monerri via Crossref Metadata Search

A perforin-like protein mediates disruption of the erythrocyte membrane during egress of Plasmodium berghei male gametocytes

Cell Microbiol
2013-03 | Journal article
DOI:

10.1111/cmi.12131
Contributors: Elena Deligianni; Rhiannon N. Morgan; Lucia Bertuccini; Christine C. Wirth; Natalie C. Silmon de Monerri; Lefteris Spanos; Michael J. Blackman; Christos Louis; Gabriele Pradel; Inga Siden-Kiamos
Source: Self-asserted source
Natalie Silmon de Monerri via Crossref Metadata Search

Global Identification of Multiple Substrates for Plasmodium falciparum SUB1, an Essential Malarial Processing Protease

Infection and Immunity
2011-01-10 | Journal article
DOI:

10.1128/iai.00902-10
Contributors: N. C. Silmon de Monerri; H. R. Flynn; M. G. Campos; F. Hackett; K. Koussis; C. Withers-Martinez; J. M. Skehel; M. J. Blackman
Source: Self-asserted source
Natalie Silmon de Monerri via Crossref Metadata Search
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