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Employment (1)

Cornell University: Ithaca, US

2020-08-01 to present | Postdoctoral associate (Department of Physics)
Employment
Source: Self-asserted source
Matthew McLeod

Education and qualifications (3)

University of Waterloo: Waterloo, Ontario, CA

2016-09-01 to 2020-08-01 | Ph.D. (Department of Biology)
Education
Source: Self-asserted source
Matthew McLeod

University of Waterloo: Waterloo, Ontario, CA

2014-09-01 to 2016-08-01 | M.Sc. (Department of Biology)
Education
Source: Self-asserted source
Matthew McLeod

University of Waterloo: Waterloo, Ontario, CA

2010-09-01 to 2014-06-01 | B.Sc - Biomedical Sciences (Department of Biology)
Education
Source: Self-asserted source
Matthew McLeod

Works (12)

A structural perspective on the temperature-dependent activity of enzymes

2024-08-23 | Preprint
Contributors: Matthew J. McLeod; Sarah A. E. Barwell; Todd Holyoak; Robert Edward Thorne
Source: check_circle
Crossref

Ice formation and its elimination in cryopreservation of bovine oocytes

2023-11-17 | Preprint
Contributors: Abdallah W. Abdelhady; David W. Mittan-Moreau; Patrick L. Crane; Matthew J. McLeod; Soon Hon Cheong; Robert E. Thorne
Source: check_circle
Crossref

Biochemical, structural, and kinetic characterization of PPi‐dependent phosphoenolpyruvate carboxykinase from Propionibacterium freudenreichii

Proteins: Structure, Function, and Bioinformatics
2023-09 | Journal article
Part of ISSN: 0887-3585
Part of ISSN: 1097-0134
Contributors: Matthew J. McLeod; Todd Holyoak
Source: Self-asserted source
Matthew McLeod

The H163A mutation unravels an oxidized conformation of the SARS-CoV-2 main protease

Nature Communications
2023-09-12 | Journal article
Contributors: Norman Tran; Sathish Dasari; Sarah A. E. Barwell; Matthew J. McLeod; Subha Kalyaanamoorthy; Todd Holyoak; Aravindhan Ganesan
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Crossref

Identifying structural and dynamic changes during the Biliverdin Reductase B catalytic cycle

Frontiers in Molecular Biosciences
2023-08-14 | Journal article
Part of ISSN: 2296-889X
Contributors: Eunjeong Lee; Matthew J. McLeod; Jasmina S. Redzic; Barbara Marcolin; Robert E. Thorne; Pratul Agarwal; Elan Zohar Eisenmesser
Source: Self-asserted source
Matthew McLeod

A metal‐dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine‐5′‐triphosphate

Protein Science
2023-06 | Journal article
Part of ISSN: 0961-8368
Part of ISSN: 1469-896X
Contributors: Matthew J. McLeod; Norman Tran; Gregory D. McCluskey; Tom D. Gillis; Stephen L. Bearne; Todd Holyoak
Source: Self-asserted source
Matthew McLeod

Enzymes | Phosphoenolpyruvate Carboxykinases

Encyclopedia of Biological Chemistry III
2021 | Book chapter
Part of ISBN: 9780128220405
Contributors: Matthew J. McLeod; Todd Holyoak
Source: Self-asserted source
Matthew McLeod

Millisecond mix-and-quench crystallography (MMQX) enables time-resolved studies of PEPCK with remote data collection

IUCrJ
2021-09-01 | Journal article
Contributors: Jonathan A. Clinger; David W. Moreau; Matthew J. McLeod; Todd Holyoak; Robert E. Thorne
Source: check_circle
Crossref

Characterization of 3-[(Carboxymethyl)thio]picolinic Acid: A Novel Inhibitor of Phosphoenolpyruvate Carboxykinase

Biochemistry
2019-09-17 | Journal article
Part of ISSN: 0006-2960
Part of ISSN: 1520-4995
Contributors: Matthew J. Mcleod; Anthony P. Krismanich; Abdeljalil Assoud; Gary I. Dmitrienko; Todd Holyoak
Source: Self-asserted source
Matthew McLeod

Asymmetric Anchoring Is Required for Efficient Ω-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase

Biochemistry
2017-04-18 | Journal article
Part of ISSN: 0006-2960
Part of ISSN: 1520-4995
Contributors: Danica S. Cui; Aron Broom; Matthew J. Mcleod; Elizabeth M. Meiering; Todd Holyoak
Source: Self-asserted source
Matthew McLeod

Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase

Biochemistry
2016-01-26 | Journal article
Part of ISSN: 0006-2960
Part of ISSN: 1520-4995
Contributors: Troy A. Johnson; Matthew J. Mcleod; Todd Holyoak
Source: Self-asserted source
Matthew McLeod

Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid

Biochemistry
2015-09-29 | Journal article
Part of ISSN: 0006-2960
Part of ISSN: 1520-4995
Contributors: Marc D. Balan; Matthew J. Mcleod; William R. Lotosky; Mark Ghaly; Todd Holyoak
Source: Self-asserted source
Matthew McLeod