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Scopus Author ID: 55910027000
ResearcherID: L-6013-2016
Loop profile: 467428

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Mexico

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Employment (2)

Nationwide Children's Hospital: Columbus, US

2024-05 to present | Research Scientist (Center for Microbial Pathogenesis)
Employment
Source: Self-asserted source
Frank Robledo-Avila

Nationwide Children's Hospital: Columbus, US

2014-01 to 2024-05 | PostDoctoral Scientist (Center for Microbial Pathogenesis)
Employment
Source: Self-asserted source
Frank Robledo-Avila

Education and qualifications (3)

Instituto Politécnico Nacional: Mexico, Distrito Federal, MX

2009 to 2013 | Ph.D. (Immunology)
Education
Source: Self-asserted source
Frank Robledo-Avila

Instituto Politécnico Nacional: Mexico, Distrito Federal, MX

2006 to 2008 | M.Sc. (Immunology)
Education
Source: Self-asserted source
Frank Robledo-Avila

Instituto Politécnico Nacional: Mexico, Distrito Federal, MX

2001 to 2006 | B.Sc.
Education
Source: Self-asserted source
Frank Robledo-Avila

Professional activities (1)

American Association of Immunologists: Md., Md., US

2016 to present
Membership
Source: Self-asserted source
Frank Robledo-Avila

Works (41)

Noninflammatory 97-amino acid High Mobility Group Box 1 derived polypeptide disrupts and prevents diverse biofilms

eBioMedicine
2024-09 | Journal article
DOI: 10.1016/j.ebiom.2024.105304
Contributors: Jaime D. Rhodes; Aishwarya Devaraj; Frank Robledo-Avila; Sabarathnam Balu; Lauren Mashburn-Warren; John R. Buzzo; Santiago Partida-Sanchez; Lauren O. Bakaletz; Steven D. Goodman
Source: check_circle
Crossref

α-Hemolysin-mediated endothelial injury contributes to the development of Staphylococcus aureus -induced dermonecrosis

Infection and Immunity
2024-08-13 | Journal article
DOI: 10.1128/iai.00133-24
Contributors: Ching Yang; Frank H. Robledo-Avila; Santiago Partida-Sanchez; Christopher P. Montgomery; Victor J. Torres
Source: check_circle
Crossref

NOD2 activation enhances macrophage Fcγ receptor function and may increase the efficacy of antibody therapy

Frontiers in Immunology
2024-06-11 | Journal article
DOI: 10.3389/fimmu.2024.1409333
Part of ISSN: 1664-3224
Contributors: Giovanna Merchand-Reyes; Mikayla F. Bull; Ramasamy Santhanam; Maria L. Valencia-Pena; Rakesh A. Murugesan; Aadesh Chordia; Xiaokui-Molly Mo; Frank H. Robledo-Avila; Juan De Dios Ruiz-Rosado; William Edgar Carson et al.
Source: Self-asserted source
Frank Robledo-Avila

42 Severe Combined Immunodeficiency Due To A Monoallelic ITPR3 Variant Presenting With Lymphohistiocytosis And Bone Marrow Failure Treated With Myeloablative Hematopoietic Cell Transplantation

Clinical Immunology
2024-05 | Conference abstract
DOI: 10.1016/j.clim.2024.109984
Part of ISSN: 1521-6616
Contributors: Megan Zavorka Thomas; Frank Robledo-Avila; Santiago Partida-Sanchez; Margaret Boyden; Samir Kahwash; Esther Knapp; Rajinder Bajwa; Roshini Abraham
Source: Self-asserted source
Frank Robledo-Avila

Cystic fibrosis macrophage function and clinical outcomes after elexacaftor/tezacaftor/ivacaftor.

The European respiratory journal
2022-10-20 | Journal article
DOI: 10.1183/13993003.02861-2021
PMID: 36265882
Contributors: Frank Robledo-Avila; Zhang S; Shrestha CL; Robledo-Avila F; Jaganathan D; Wisniewski BL; Brown N; Pham H; Carey K; Amer AO et al.
Source: Self-asserted source
Frank Robledo-Avila
grade
Preferred source (of 2)‎

Disruption of Nurse-like Cell Differentiation as a Therapeutic Strategy for Chronic Lymphocytic Leukemia.

Journal of immunology (Baltimore, Md. : 1950)
2022-08-22 | Journal article | Methodology, Conceptualization, Investigation
DOI: 10.4049/jimmunol.2100931
PMID: 35995507
Contributors: Frank Robledo-Avila
Source: Self-asserted source
Frank Robledo-Avila
grade
Preferred source (of 2)‎

Abstract LB050: Targeting cells in the microenvironment as a novel therapeutic strategy for chronic lymphocytic leukemia

Cancer Research
2022-06-15 | Conference abstract
DOI: 10.1158/1538-7445.am2022-lb050
Part of ISSN: 1538-7445
Contributors: Giovanna Merchand Reyes; Ramasamy Santhanam; Frank H. Robledo Avila; Christoph Weigel; Juan D. Ruiz Rosado; Xiaokui Mo; Santiago Partida Sanchez; Jennifer A. Woyach; Christopher C. Oakes; Susheela Tridandapani et al.
Source: Self-asserted source
Frank Robledo-Avila

Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and immunothrombosis.

Proceedings of the National Academy of Sciences of the United States of America
2022-05-19 | Journal article
DOI: 10.1073/pnas.2202012119
PMID: 35588457
Source: Self-asserted source
Frank Robledo-Avila

Contrasting roles for neutrophils and macrophages during experimental pyelonephritis

The Journal of Immunology
2022-05-01 | Conference abstract
DOI: 10.4049/jimmunol.208.supp.163.13
Part of ISSN: 0022-1767
Part of ISSN: 1550-6606
Contributors: Juan de Dios Ruiz Rosado; Hanna Cortado; Frank Robledo-Avila; John David Spencer; Brian Becknell; Santiago Partida-Sanchez
Source: Self-asserted source
Frank Robledo-Avila

CFTR Modulators Restore Acidification of Autophago-Lysosomes and Bacterial Clearance in Cystic Fibrosis Macrophages.

Frontiers in cellular and infection microbiology
2022-02-16 | Journal article
DOI: 10.3389/fcimb.2022.819554
PMID: 35252032
PMC: PMC8890004
Source: Self-asserted source
Frank Robledo-Avila

383: Cystic fibrosis macrophage function after elexacaftor/tezacaftor/ivacaftor initiation

Journal of Cystic Fibrosis
2021-11 | Conference abstract
DOI: 10.1016/s1569-1993(21)01807-5
Part of ISSN: 1569-1993
Contributors: S. Zhang; F. Robledo; C. Shrestha; B. Wisniewski; N. Brown; K. Carey; H. Pham; S. Partida-Sanchez; B. Kopp
Source: Self-asserted source
Frank Robledo-Avila

493: Effects of elexacaftor/tezacaftor/ivacaftor on antimicrobial functions of CF neutrophils

Journal of Cystic Fibrosis
2021-11 | Conference abstract
DOI: 10.1016/s1569-1993(21)01917-2
Part of ISSN: 1569-1993
Contributors: F. Robledo; B. Kopp; S. Partida-Sanchez
Source: Self-asserted source
Frank Robledo-Avila

Z-form extracellular DNA is a structural component of the bacterial biofilm matrix

Cell
2021-11 | Journal article
DOI: 10.1016/j.cell.2021.10.010
Part of ISSN: 0092-8674
Source: Self-asserted source
Frank Robledo-Avila

The extracellular innate-immune effector HMGB1 limits pathogenic bacterial biofilm proliferation

Journal of Clinical Investigation
2021-08-16 | Journal article
DOI: 10.1172/jci140527
Part of ISSN: 1558-8238
Source: Self-asserted source
Frank Robledo-Avila

Functional CFTR channel is essential for effective antimicrobial activities of neutrophils

The Journal of Immunology
2021-05-01 | Conference abstract
DOI: 10.4049/jimmunol.206.supp.112.20
Part of ISSN: 0022-1767
Part of ISSN: 1550-6606
Contributors: Frank Hanz Robledo Avila; Benjamin T Kopp; Santiago Partida-Sanchez
Source: Self-asserted source
Frank Robledo-Avila

Neutrophil-Macrophage Imbalance Drives the Development of Renal Scarring during Experimental Pyelonephritis

Journal of the American Society of Nephrology
2021-01 | Journal article
DOI: 10.1681/ASN.2020030362
Contributors: Juan de Dios Ruiz-Rosado; Frank Robledo-Avila; Hanna Cortado; Javier Rangel-Moreno; Sheryl S. Justice; Ching Yang; John David Spencer; Brian Becknell; Santiago Partida-Sanchez
Source: check_circle
Crossref

A Bacterial Epigenetic Switch in Non-typeable Haemophilus influenzae Modifies Host Immune Response During Otitis Media

Frontiers in Cellular and Infection Microbiology
2020-10-23 | Journal article
DOI: 10.3389/fcimb.2020.512743
Part of ISSN: 2235-2988
Source: Self-asserted source
Frank Robledo-Avila

Características generales de la respuesta inmunológica

Inmunología molecular, celular y traslacional
2020-09-23 | Book chapter | Writing - original draft
Contributors: Frank Robledo-Avila
Source: Self-asserted source
Frank Robledo-Avila

Antibody-mediated protection against Staphylococcus aureus dermonecrosis: synergy of toxin neutralization and neutrophil recruitment.

The Journal of investigative dermatology
2020-09-15 | Journal article
DOI: 10.1016/j.jid.2020.09.001
PMID: 32946878
Source: Self-asserted source
Frank Robledo-Avila
grade
Preferred source (of 2)‎

The emerging roles of neutrophils and macrophages during experimental acute pyelonephritis

The Journal of Immunology
2020-05-01 | Conference abstract
DOI: 10.4049/jimmunol.204.supp.148.12
Part of ISSN: 0022-1767
Part of ISSN: 1550-6606
Contributors: Juan de Dios Ruiz Rosado; Frank Robledo-Avila; Brian Becknell; Santiago Partida-Sanchez
Source: Self-asserted source
Frank Robledo-Avila

The TRPM2 ion channel regulates the inflammatory response of neutrophils during <i>Listeria monocytogenes</i> infection

The Journal of Immunology
2020-05-01 | Conference abstract
DOI: 10.4049/jimmunol.204.supp.148.23
Part of ISSN: 0022-1767
Part of ISSN: 1550-6606
Contributors: Frank Hanz Robledo-Avila; Juan de Dios Ruiz Rosado; Kenneth L Brockman; Santiago Partida-Sanchez
Source: Self-asserted source
Frank Robledo-Avila

The TRPM2 Ion Channel Regulates Inflammatory Functions of Neutrophils During Listeria monocytogenes Infection.

Frontiers in immunology
2020-02-04 | Journal article
DOI: 10.3389/fimmu.2020.00097
PMID: 32117251
PMC: PMC7010865
Source: Self-asserted source
Frank Robledo-Avila

CD31 Acts as a Checkpoint Molecule and Is Modulated by FcγR-Mediated Signaling in Monocytes

The Journal of Immunology
2019-12-15 | Journal article
DOI: 10.4049/jimmunol.1900059
Contributors: Giovanna Merchand-Reyes; Frank H Robledo-Avila; Nathaniel J Buteyn; Shalini Gautam; Ramasamy Santhanam; Kavin Fatehchand; Xiaokui Mo; Santiago Partida-Sanchez; Jonathan P Butchar; Susheela Tridandapani
Source: check_circle
Crossref

Caspase-11 Mediates Neutrophil Chemotaxis and Extracellular Trap Formation During Acute Gouty Arthritis Through Alteration of Cofilin Phosphorylation

Frontiers in Immunology
2019-11-15 | Journal article
DOI: 10.3389/fimmu.2019.02519
Part of ISSN: 1664-3224
Source: Self-asserted source
Frank Robledo-Avila

Whole-blood transcriptomic responses to lumacaftor/ivacaftor therapy in cystic fibrosis.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
2019-08-29 | Journal article
DOI: 10.1016/j.jcf.2019.08.021
PMID: 31474496
Source: Self-asserted source
Frank Robledo-Avila

CD31 acts as a checkpoint molecule and is modulated by FcγR-mediated signaling in monocytes

The Journal of Immunology
2019-05-01 | Conference abstract
DOI: 10.4049/jimmunol.202.supp.59.12
Part of ISSN: 0022-1767
Part of ISSN: 1550-6606
Contributors: Jonathan P Butchar; Giovanna Merchand-Reyes; Frank Robledo-Avila; Nathaniel Buteyn; Shalini Gautam; Ramasamy Santhanam; Kavin Fatehchand; Santiago Partida-Sanchez; Susheela Tridandapani
Source: Self-asserted source
Frank Robledo-Avila

AR-13 reduces antibiotic-resistant bacterial burden in cystic fibrosis phagocytes and improves cystic fibrosis transmembrane conductance regulator function.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
2018-10 | Journal article
DOI: 10.1016/j.jcf.2018.10.010
PMID: 30366849
Contributors: Assani K; Shrestha CL; Rinehardt H; Zhang S; Robledo-Avila F; Wellmerling J; Partida-Sanchez S; Cormet-Boyaka E; Reynolds SD; Schlesinger LS et al.
Source: Self-asserted source
Frank Robledo-Avila via Europe PubMed Central

Dysregulated Calcium Homeostasis in Cystic Fibrosis Neutrophils Leads to Deficient Antimicrobial Responses.

Journal of immunology (Baltimore, Md. : 1950)
2018-08 | Journal article
DOI: 10.4049/jimmunol.1800076
PMID: 30120123
Contributors: Robledo-Avila FH; Ruiz-Rosado JD; Brockman KL; Kopp BT; Amer AO; McCoy K; Bakaletz LO; Partida-Sanchez S
Source: Self-asserted source
Frank Robledo-Avila via Europe PubMed Central

Helminth-induced Ly6<sup>Chi</sup> monocyte-derived alternatively activated macrophages suppress experimental autoimmune encephalomyelitis

Scientific Reports
2017 | Journal article
DOI: 10.1038/srep40814
EID:

2-s2.0-85009858788
Contributors: De Dios Ruiz-Rosado, J.; Diana, M.-S.; Frank, R.-A.; Miriam, R.-S.M.; Guerau-De-Arellano, M.; Santiago, P.-S.; Terrazas, C.; Amici, S.A.; Jablonski, K.A.; Webb, L.M. et al.
Source: Self-asserted source
Frank Robledo-Avila via Scopus - Elsevier

Human cystic fibrosis macrophages have defective calcium-dependent protein kinase c activation of the nadph oxidase, an effect augmented by burkholderia cenocepacia

Journal of Immunology
2017 | Journal article
DOI: 10.4049/jimmunol.1502609
EID:

2-s2.0-85014916134
Contributors: Assani, K.; Shrestha, C.L.; Robledo-Avila, F.; Rajaram, M.V.; Partida-Sanchez, S.; Schlesinger, L.S.; Kopp, B.T.
Source: Self-asserted source
Frank Robledo-Avila via Scopus - Elsevier

The expression of Mirc1/Mir17–92 cluster in sputum samples correlates with pulmonary exacerbations in cystic fibrosis patients

Journal of Cystic Fibrosis
2017 | Journal article
DOI: https://doi.org/10.1016/j.jcf.2017.11.005
Source: Self-asserted source
Frank Robledo-Avila

The ModA2 Phasevarion of nontypeable Haemophilus influenzae Regulates Resistance to Oxidative Stress and Killing by Human Neutrophils

Scientific Reports
2017-06-09 | Journal article
DOI: 10.1038/s41598-017-03552-9
Contributors: Kenneth L. Brockman; M. Taylor Branstool; John M. Atack; Frank Robledo-Avila; Santiago Partida-Sanchez; Michael P. Jennings; Lauren O. Bakaletz
Source: check_circle
Crossref

MIF promotes classical activation and conversion of inflammatory Ly6C<sup>high</sup> monocytes into TipDCs during murine toxoplasmosis

Mediators of Inflammation
2016 | Journal article
DOI: 10.1155/2016/9101762
EID:

2-s2.0-84962217296
Contributors: Ruiz-Rosado, J.D.D.; Olguín, J.E.; Juárez-Avelar, I.; Saavedra, R.; Terrazas, L.I.; Robledo-Avila, F.H.; Vazquez-Mendoza, A.; Fernández, J.; Satoskar, A.R.; Partida-Sánchez, S. et al.
Source: Self-asserted source
Frank Robledo-Avila via Scopus - Elsevier

TGF-β receptor 1 inhibition prevents stenosis of tissue-engineered vascular grafts by reducing host mononuclear phagocyte activation

FASEB Journal
2016 | Journal article
DOI: 10.1096/fj.201500179R
EID:

2-s2.0-84978034194
Contributors: Lee, Y.-U.; De Dios Ruiz-Rosado, J.; Mahler, N.; Best, C.A.; Tara, S.; Yi, T.; Shoji, T.; Sugiura, T.; Lee, A.Y.; Robledo-Avila, F. et al.
Source: Self-asserted source
Frank Robledo-Avila via Scopus - Elsevier

Características generales de la respuesta inmunológica

Inmunología molecular, celular y traslacional
2016-06-01 | Book chapter
Part of ISBN: 9788416004867
Source: Self-asserted source
Frank Robledo-Avila

Dialyzable leukocyte extracts activate TLR-2 on monocytes.

Natural product communications
2014-06 | Journal article
PMID: 25115098
Contributors: García-Hernández U; Robledo-Avila FH; Alvarez-Jiménez VD; Rodríguez-Cortés O; Wong-Baeza I; Serafín-López J; Aguilar-Anguiano LM; Estrada-Parra S; Chacón-Salinas R
Source: Self-asserted source
Frank Robledo-Avila via Europe PubMed Central

Low-dose amphotericin b and murine dialyzable spleen extracts protect against systemic candida infection in mice

Clinical and Developmental Immunology
2013 | Journal article
DOI: 10.1155/2013/194064
EID:

2-s2.0-84885344822
Contributors: Robledo-Ávila, F.; Pérez-Tapia, M.; Limón-Flores, A.; Pavon, L.; Hernández-Pando, R.; Wong-Baeza, I.; González-González, G.; Tovar, C.; Estrada-Parra, S.; Estrada-García, I.
Source: Self-asserted source
Frank Robledo-Avila via Scopus - Elsevier

Aplicaciones terapéuticas de los agonistas de TLRs

Rev Fac Med
2009-07 | Journal article
Source: Self-asserted source
Frank Robledo-Avila

Use of DLE as treatment in murine endotoxic shock (41.54)

The Journal of Immunology
2009-04-01 | Conference abstract
DOI: 10.4049/jimmunol.182.supp.41.54
Part of ISSN: 0022-1767
Part of ISSN: 1550-6606
Contributors: Frank Hanz Robledo Avila; Said Kayum Vazquez Leyba; Estela Valderrabano Ortiz; Marisol De la Fuente Granada; Sonia Mayra Perez Tapia; Iris Estrada Garcia; Sergio Estrada Parra
Source: Self-asserted source
Frank Robledo-Avila

Human dialyzable leukocyte extracts (DLE) have ligands for TLR- 2 but not for TLR-4 (49.34)

The Journal of Immunology
2007-04-01 | Conference abstract
DOI: 10.4049/jimmunol.178.supp.49.34
Part of ISSN: 0022-1767
Part of ISSN: 1550-6606
Contributors: FRANK ROBLEDO-AVILA; ISABEL WONG-BAEZA; JEANET SERAFIN-LOPEZ; ARMANDO ISIBASI-ARAUJO; CONSTANTINO LOPEZ-MACIAS; SONIA MAYRA PEREZ-TAPIA; IRIS CITLALLI ESTRADA-GARCIA; SERGIO ANTONIO ESTRADA-PARRA
Source: Self-asserted source
Frank Robledo-Avila

Angiotensin II receptor I blockade prevents stenosis of tissue engineered vascular grafts

The FASEB Journal
Journal article
DOI: 10.1096/fj.201800458
Source: Self-asserted source
Frank Robledo-Avila

Peer review (1 review for 1 publication/grant)

Review activity for PloS one. (1)
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