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Works (29)

Autoantibodies to joint-related peptides as predictive markers in early rheumatoid arthritis

Rheumatology
2024-07-30 | Journal article
DOI: 10.1093/rheumatology/keae382
Part of ISSN: 1462-0332
Contributors: Monica Leu Agelii; Outi Sareila; Erik Lönnblom; Lei Cheng; Kristina Forslind; Ingiäld Hafström; Maria Andersson; Alf Kastbom; Christopher Sjöwall; Lennart T H Jacobsson et al.
Source: Self-asserted source
Outi Sareila via Crossref Metadata Search

Human MHC Class II and Invariant Chain Knock‐in Mice Mimic Rheumatoid Arthritis with Allele Restriction in Immune Response and Arthritis Association

Advanced Science
2024-04-11 | Journal article
DOI: 10.1002/advs.202401513
Part of ISSN: 2198-3844
Contributors: Laura Romero-Castillo; Taotao Li; Nhu‐Nguyen Do; Outi Sareila; Bingze Xu; Viktoria Hennings; Zhongwei Xu; Carolin Svensson; Ana Oliveira‐Coelho; Zeynep Sener et al.
Source: Self-asserted source
Outi Sareila via Crossref Metadata Search

Autoantibodies to Disease‐Related Proteins in Joints as Novel Biomarkers for the Diagnosis of Rheumatoid Arthritis

Arthritis & Rheumatology
2023-07 | Journal article
DOI: 10.1002/art.42463
Contributors: Erik Lönnblom; Monica Leu Agelii; Outi Sareila; Lei Cheng; Bingze Xu; Johan Viljanen; Ingiäld Hafström; Maria L. E. Andersson; Göran Bergström; Anna‐Karin Hultgård Ekwall et al.
Source: check_circle
Crossref

Pathogenic antibody response to glucose-6-phosphate isomerase targets a modified epitope uniquely exposed on joint cartilage

Annals of the Rheumatic Diseases
2023-06 | Journal article
DOI: 10.1136/ard-2022-223633
Contributors: Taotao Li; Changrong Ge; Alexander Krämer; Outi Sareila; Monica Leu Agelii; Linda Johansson; Kristina Forslind; Erik Lönnblom; Min Yang; Bingze Xu et al.
Source: check_circle
Crossref

Early increase of circulating transitional B cells and autoantibodies to joint-related proteins in patients with metastatic melanoma developing checkpoint inhibitor-induced inflammatory arthritis.

Arthritis & rheumatology (Hoboken, N.J.)
2022-11 | Journal article
DOI: 10.1002/art.42406
PMID: 36409578
Contributors: Gatto M; Bjursten S; Jonsson CA; Leu Agelii M; Jonell C; McGrath S; Lönnblom E; Sareila O; Holmdahl R; Rudin A et al.
Source: Self-asserted source
Outi Sareila via Europe PubMed Central
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Variants of beta-glucan polysaccharides downregulate autoimmune inflammation.

Communications biology
2022-05 | Journal article
DOI: 10.1038/s42003-022-03376-y
PMID: 35551269
PMC: PMC9098905
Contributors: Fahlquist-Hagert C; Sareila O; Rosendahl S; Holmdahl R
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Chronic Active Arthritis Driven by Macrophages Without Involvement of T Cells: A Novel Experimental Model of Rheumatoid Arthritis.

Arthritis & rheumatology (Hoboken, N.J.)
2018-06 | Journal article
DOI: 10.1002/art.40482
PMID: 29513929
Contributors: Hagert C; Sareila O; Kelkka T; Nandakumar KS; Collin M; Xu B; Guérard S; Bäcklund J; Jalkanen S; Holmdahl R
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

The Macrophage Mannose Receptor Regulate Mannan-Induced Psoriasis, Psoriatic Arthritis, and Rheumatoid Arthritis-Like Disease Models.

Frontiers in immunology
2018-02 | Journal article
DOI: 10.3389/fimmu.2018.00114
PMID: 29467756
PMC: PMC5808283
Contributors: Hagert C; Sareila O; Kelkka T; Jalkanen S; Holmdahl R
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Reactive oxygen species regulate both priming and established arthritis, but with different mechanisms.

2017-05 | Journal article
DOI: 10.1089/ars.2016.6981
PMID: 28467721
Contributors: Sareila O; Hagert C; Kelkka T; Linja M; Xu B; Kihlberg J; Holmdahl R
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

(18)F-Labeling of Mannan for Inflammation Research with Positron Emission Tomography.

2016-09 | Journal article
DOI: 10.1021/acsmedchemlett.6b00160
PMID: 27660685
Contributors: Li XG; Hagert C; Siitonen R; Virtanen H; Sareila O; Liljenbäck H; Tuisku J; Knuuti J; Bergman J; Holmdahl R et al.
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Ncf1 polymorphism reveals oxidative regulation of autoimmune chronic inflammation.

2016-01 | Journal article
DOI: 10.1111/imr.12378
PMID: 26683156
Contributors: Holmdahl R; Sareila O; Olsson LM; Bäckdahl L; Wing K
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.

2015 | Journal article
DOI: 10.1371/journal.pone.0141974
PMID: 26528554
PMC: PMC4631371
Contributors: Sareila O; Hagert C; Rantakari P; Poutanen M; Holmdahl R
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Reactive oxygen species deficiency induces autoimmunity with type 1 interferon signature.

2014-12 | Journal article
DOI: 10.1089/ars.2013.5828
PMID: 24787605
Contributors: Kelkka T; Kienhöfer D; Hoffmann M; Linja M; Wing K; Sareila O; Hultqvist M; Laajala E; Chen Z; Vasconcelos J et al.
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

In vivo imaging of reactive oxygen and nitrogen species in murine colitis.

2014-08 | Journal article
DOI: 10.1097/MIB.0000000000000118
PMID: 24983980
Contributors: Asghar MN; Emani R; Alam C; Helenius TO; Grönroos TJ; Sareila O; Din MU; Holmdahl R; Hänninen A; Toivola DM
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Hydrogen peroxide as an immunological transmitter regulating autoreactive T cells.

2013-04 | Journal article
DOI: 10.1089/ars.2012.4734
PMID: 22900704
Contributors: Holmdahl R; Sareila O; Pizzolla A; Winter S; Hagert C; Jaakkola N; Kelkka T; Olsson LM; Wing K; Bäckdahl L
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Identification of a region in p47phox/NCF1 crucial for phagocytic NADPH oxidase (NOX2) activation.

2013-03 | Journal article
DOI: 10.1189/jlb.1211588
PMID: 23271700
PMC: PMC3579024
Contributors: Sareila O; Jaakkola N; Olofsson P; Kelkka T; Holmdahl R
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Superoxide dismutase 3 limits collagen-induced arthritis in the absence of phagocyte oxidative burst.

2012 | Journal article
DOI: 10.1155/2012/730469
PMID: 22529530
PMC: PMC3317049
Contributors: Kelkka T; Laurila JP; Sareila O; Olofsson P; Laukkanen MO; Holmdahl R
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Dual specificity phosphatase 1 regulates human inducible nitric oxide synthase expression by p38 MAP kinase.

2011 | Journal article
DOI: 10.1155/2011/127587
PMID: 21547253
PMC: PMC3086212
Contributors: Turpeinen T; Nieminen R; Taimi V; Heittola T; Sareila O; Clark AR; Moilanen E; Korhonen R
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

NOX2 complex-derived ROS as immune regulators.

2011-10 | Journal article
DOI: 10.1089/ars.2010.3635
PMID: 20919938
Contributors: Sareila O; Kelkka T; Pizzolla A; Hultqvist M; Holmdahl R
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Synthesis and anti-inflammatory effects of a series of novel 7-hydroxycoumarin derivatives.

2011-09 | Journal article
DOI: 10.1016/j.ejmech.2011.05.052
PMID: 21680063
Contributors: Timonen JM; Nieminen RM; Sareila O; Goulas A; Moilanen LJ; Haukka M; Vainiotalo P; Moilanen E; Aulaskari PH
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Positioning of a polymorphic quantitative trait nucleotide in the Ncf1 gene controlling oxidative burst response and arthritis severity in rats.

2011-06 | Journal article
DOI: 10.1089/ars.2010.3440
PMID: 21275845
Contributors: Hultqvist M; Sareila O; Vilhardt F; Norin U; Olsson LM; Olofsson P; Hellman U; Holmdahl R
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Bacterial DNA delays human eosinophil apoptosis.

2009-06 | Journal article
DOI: 10.1016/j.pupt.2008.11.012
PMID: 19073274
Contributors: Ilmarinen P; Hasala H; Sareila O; Moilanen E; Kankaanranta H
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Effects of levo- and dextrosimendan on NF-kappaB-mediated transcription, iNOS expression and NO production in response to inflammatory stimuli.

2008-11 | Journal article
DOI: 10.1038/bjp.2008.328
PMID: 19002103
PMC: PMC2597247
Contributors: Sareila O; Korhonen R; Auvinen H; Hämäläinen M; Kankaanranta H; Nissinen E; Moilanen E
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Orazipone inhibits activation of inflammatory transcription factors nuclear factor-kappa B and signal transducer and activator of transcription 1 and decreases inducible nitric-oxide synthase expression and nitric oxide production in response to inflammatory stimuli.

2008-02 | Journal article
DOI: 10.1124/jpet.107.129114
PMID: 18039960
Contributors: Sareila O; Hämäläinen M; Nissinen E; Kankaanranta H; Moilanen E
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Janus kinase 3 inhibitor WHI-P154 in macrophages activated by bacterial endotoxin: differential effects on the expression of iNOS, COX-2 and TNF-alpha.

2008-01 | Journal article
DOI: 10.1016/j.intimp.2007.10.016
PMID: 18068105
Contributors: Sareila O; Korhonen R; Kärpänniemi O; Nieminen R; Kankaanranta H; Moilanen E
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

PPARalpha agonists inhibit nitric oxide production by enhancing iNOS degradation in LPS-treated macrophages.

2007-12 | Journal article
DOI: 10.1038/sj.bjp.0707477
PMID: 17891158
PMC: PMC2095111
Contributors: Paukkeri EL; Leppänen T; Sareila O; Vuolteenaho K; Kankaanranta H; Moilanen E
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Inhibition of p38 mitogen-activated protein kinase enhances c-Jun N-terminal kinase activity: implication in inducible nitric oxide synthase expression.

2006 | Journal article
DOI: 10.1186/1471-2210-6-5
PMID: 16504051
PMC: PMC1402273
Contributors: Lahti A; Sareila O; Kankaanranta H; Moilanen E
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

JAK inhibitors AG-490 and WHI-P154 decrease IFN-gamma-induced iNOS expression and NO production in macrophages.

2006 | Journal article
DOI: 10.1155/mi/2006/16161
PMID: 16883061
PMC: PMC1592588
Contributors: Sareila O; Korhonen R; Kärpänniemi O; Nieminen R; Kankaanranta H; Moilanen E
Source: Self-asserted source
Outi Sareila via Europe PubMed Central

Inhibition of classical PKC isoenzymes downregulates STAT1 activation and iNOS expression in LPS-treated murine J774 macrophages.

2006-04 | Journal article
DOI: 10.1038/sj.bjp.0706672
PMID: 16432499
PMC: PMC1751509
Contributors: Salonen T; Sareila O; Jalonen U; Kankaanranta H; Tuominen R; Moilanen E
Source: Self-asserted source
Outi Sareila via Europe PubMed Central
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