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Emails & domains

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Keywords

Liver fibrosis, Fibroblasts, Dairy cow, Metabolism diseases, Ketosis, Fatty liver, Portal fibroblasts

Countries

China

Activities

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Employment (2)

Jilin University: Changchun, CN

2023-12-29 to present | Associate professor (College of Veterinary Medicine)
Employment
Source: Self-asserted source
LIN LEI

Jilin University: Changchun, CN

2021-04-29 to 2023-12-28 | Postdoc (College of Veterinary Medicine)
Employment
Source: Self-asserted source
LIN LEI

Education and qualifications (1)

Sorbonne Université: Paris, FR

2016-10-02 to 2020-09-24 | PhD (PHYSIOLOGIE, PHYSIOPATHOLOGIE ET THÉRAPEUTIOUE)
Education
Source: Self-asserted source
LIN LEI

Works (19)

Caveolin 1 ameliorates nonesterified fatty acid–induced oxidative stress via the autophagy regulator beclin 1 in bovine mammary gland epithelial cells

Journal of Dairy Science
2025-01 | Journal article
DOI: 10.3168/jds.2024-25245
Contributors: Kai Liu; Yifei Dong; Liguang Cao; Guojin Li; Zifeng Yang; Jianchun Luo; Lin Lei; Xiliang Du; Yuxiang Song; Muhammad Usman et al.
Source: check_circle
Crossref

Expression of hepatic genes involved in bile acid metabolism in dairy cows with fatty liver

Journal of Dairy Science
2024-10 | Journal article
DOI: 10.3168/jds.2023-24485
Contributors: Xiliang Du; Mingchao Liu; Erminio Trevisi; Lingxue Ju; Yuting Yang; Wenwen Gao; Yuxiang Song; Lin Lei; Majigsuren Zolzaya; Xinwei Li et al.
Source: check_circle
Crossref

Targeting PHB2-mediated mitophagy alleviates nonesterified fatty acid-induced mitochondrial dysfunction in bovine mammary epithelial cells

Journal of Dairy Science
2024-10 | Journal article
DOI: 10.3168/jds.2024-24800
Contributors: Guojin Li; Liguang Cao; Kai Liu; Yifei Dong; Zifeng Yang; Jianchun Luo; Wenrui Gao; Lin Lei; Yuxiang Song; Xiliang Du et al.
Source: check_circle
Crossref

Research Progress on the Role of M6A in Regulating Economic Traits in Livestock

International Journal of Molecular Sciences
2024-07-31 | Journal article
DOI: 10.3390/ijms25158365
Contributors: Tuanhui Ren; Meng Xu; Xinyu Du; Yanxi Wang; Juan J. Loor; Lin Lei; Wenwen Gao; Xiliang Du; Yuxiang Song; Guowen Liu et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Thioredoxin-2 suppresses hydrogen peroxide–activated nuclear factor kappa B signaling via alleviating oxidative stress in bovine adipocytes

Journal of Dairy Science
2024-06 | Journal article
DOI: 10.3168/jds.2023-23465
Contributors: Xue Hao; Mingchao Liu; Xiao Zhang; Hao Yu; Zhiyuan Fang; Xinxing Gao; Meng Chen; Qi Shao; Wenwen Gao; Lin Lei et al.
Source: check_circle
Crossref

Inhibition of cluster antigen 36 protects against fatty acid-induced lipid accumulation, oxidative stress, and inflammation in bovine hepatocytes

Journal of Dairy Science
2023-12 | Journal article
DOI: 10.3168/jds.2023-23282
Contributors: Chenchen Zhao; Jinxia Li; Menglin Liu; Linfang Chen; Yiwei Zhu; Wenwen Gao; Xiliang Du; Yuxiang Song; Guowen Liu; Lin Lei et al.
Source: check_circle
Crossref

Low abundance of insulin-induced gene 1 contributes to SREBP-1c processing and hepatic steatosis in dairy cows with severe fatty liver

Journal of Dairy Science
2023-08 | Journal article
DOI: 10.3168/jds.2022-22895
Contributors: Yiwei Zhu; Lin Lei; Xinghui Wang; Qianming Jiang; Juan J. Loor; Fanrong Kong; Linfang Chen; Jinxia Li; Chenchen Zhao; Menglin Liu et al.
Source: check_circle
Crossref

AdipoRon alleviates fatty acid-induced lipid accumulation and mitochondrial dysfunction in bovine hepatocytes by promoting autophagy.

Journal of dairy science
2023-06-01 | Journal article
DOI: 10.3168/jds.2022-22723
PMID: 37268562
Contributors: Zhao C; Wu B; Li J; Qianming Jiang; Loor JJ; Liu M; Chen L; Zhu Y; Gao W; Du X et al.
Source: Self-asserted source
LIN LEI

The E3 ubiquitin ligase NEDD4-1 protects against acetaminophen-induced liver injury by targeting VDAC1 for degradation

Acta Pharmaceutica Sinica B
2023-04 | Journal article
DOI: 10.1016/j.apsb.2023.01.019
Contributors: Yiwei Zhu; Lin Lei; Xinghui Wang; Linfang Chen; Wei Li; Jinxia Li; Chenchen Zhao; Xiliang Du; Yuxiang Song; Wenwen Gao et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Liver fibrosis is a common pathological change in the liver of dairy cows with fatty liver.

Journal of dairy science
2023-02-22 | Journal article
DOI: 10.3168/jds.2022-22021
PMID: 36823013
Contributors: Zhang C; Shao Q; Liu M; Wang X; Loor JJ; Jiang Q; Cuan S; Li X; Wang J; Li Y et al.
Source: Self-asserted source
LIN LEI

Nuciferine Ameliorates Nonesterified Fatty Acid-Induced Bovine Mammary Epithelial Cell Lipid Accumulation, Apoptosis, and Impaired Migration via Activating LKB1/AMPK Signaling Pathway.

Journal of agricultural and food chemistry
2022-12-27 | Journal article | Author
DOI: 10.1021/acs.jafc.2c06133
PMID: 36573646
Contributors: Li J; Zhao C; Liu M; Chen L; Yiwei Zhu; Gao W; Xiliang Du; Song Y; Xinwei Li; Liu G et al.
Source: Self-asserted source
LIN LEI

Impaired autophagy aggravates oxidative stress in mammary gland of dairy cows with clinical ketosis

Journal of Dairy Science
2022-07 | Journal article
DOI: 10.3168/jds.2021-21234
Contributors: Kaiming Yue; Xudong Pu; Juan J. Loor; Qianming Jiang; Jihong Dong; Taiyu Shen; Guojin Li; Wenwen Gao; Lin Lei; Xiliang Du et al.
Source: check_circle
Crossref

Targeting IRE1α and PERK in the endoplasmic reticulum stress pathway attenuates fatty acid-induced insulin resistance in bovine hepatocytes.

Journal of dairy science
2022-07-13 | Journal article
DOI: 10.3168/jds.2021-21754
PMID: 35840398
Contributors: Fang Z; Gao W; Qianming Jiang; Loor JJ; Zhao C; Du X; Zhang M; Song Y; Wang Z; Liu G et al.
Source: Self-asserted source
LIN LEI

Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis.

Hepatology (Baltimore, Md.)
2022-03-29 | Journal article
DOI: 10.1002/hep.32456
PMID: 35278227
Contributors: Lei L; Alix Bruneau; El Mourabit H; Guégan J; Folseraas T; Lemoinne S; Karlsen TH; Benedicte Hoareau; Morichon R; Ester Gonzalez-Sanchez et al.
Source: Self-asserted source
LIN LEI

Reducing hepatic endoplasmic reticulum stress ameliorates the impairment in insulin signaling induced by high levels of β-hydroxybutyrate in bovine hepatocytes.

Journal of dairy science
2021-09-16 | Journal article
DOI: 10.3168/jds.2021-20611
PMID: 34538494
Contributors: Lei L; Gao W; Juan Loor; Ahmad A Aboragah; Fang Z; Du X; Zhang M; Song Y; Liu G; Li X
Source: Self-asserted source
LIN LEI

Propionate alleviates palmitic acid-induced endoplasmic reticulum stress by enhancing autophagy in calf hepatic cells.

Journal of dairy science
2021-05-15 | Journal article
DOI: 10.3168/jds.2020-19969
PMID: 34001357
Contributors: Gao W; Fang Z; Lei L; Ju L; Jin B; Juan Loor; Yusheng Liang; Shi Z; Shen T; Yu H et al.
Source: Self-asserted source
LIN LEI

Role of Angiogenesis in the Pathogenesis of NAFLD

Journal of Clinical Medicine
2021-03 | Journal article | Author
DOI: 10.3390/jcm10071338
Contributors: LIN LEI; Haquima El Mourabit-El Mezdioui; Chantal Housset; Axelle Cadoret; Sara Lemoinne
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

NEFA-induced ROS impaired insulin signalling through the JNK and p38MAPK pathways in non-alcoholic steatohepatitis.

Journal of cellular and molecular medicine
2018-03-30 | Journal article
DOI: 10.1111/jcmm.13617
PMID: 29602237
PMC: PMC6010831
Contributors: Gao W; Xiliang Du; Lei L; Wang H; Zhang M; Wang Z; Li X; Guowen Liu; Xinwei Li
Source: Self-asserted source
LIN LEI

Alpha-lipoic acid attenuates endoplasmic reticulum stress-induced insulin resistance by improving mitochondrial function in HepG2 cells.

Cellular signalling
2016-07-01 | Journal article
DOI: 10.1016/j.cellsig.2016.06.024
PMID: 27377964
Contributors: Lei L; Yiwei Zhu; Gao W; Xiliang Du; Zhang M; Peng Z; Fu S; Li X; Zhe W; Li X et al.
Source: Self-asserted source
LIN LEI
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