Personal information
Verified email addresses
Biography
We focus our interest on two important groups of proteins: molecular chaperones and flavoenzymes. We search for structure-function relationships as well as their metabolic insertion in the cell. These proteins are widely distributed among living organisms and they have relevant roles in cells in normal or stressful conditions.
We are particularly interested in the structural backgrounds that allow these proteins to fulfill their roles efficiently. We study the rules that govern substrate recognition, the activity regulation by the cell environment and the interaction with other cell proteins.
Our experimental strategies involve studies with wild type and mutant recombinant enzymes, natural and artificial substrates and isolated organelles. We use as models enzymes those from rice, pea, Arabidopsis thaliana and Leptospira interrogans as well as from other bacteria.