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Genetics, Type 2 Diabetes, Obesity, Insulin Resistance
United Kingdom

Activities

Employment (3)

University of Exeter: Exeter, Devon, GB

2020-01-01 to present | Professor (Exeter Centre of Excellence for Diabetes Research)
Employment
Source: Self-asserted source
Ines Barroso

MRC Epidemiology Unit : Cambridge, Cambridgeshire, GB

2019-02-01 to 2019-12-31
Employment
Source: Self-asserted source
Ines Barroso

Wellcome Sanger Institute: Cambridge, GB

2002-10 to 2019-01-31 | Senior Group Leader Metabolic Disease (Human Genetics)
Employment
Source: Self-asserted source
Ines Barroso

Education and qualifications (3)

University of Pavia: Pavia, IT

2003-12 | MSc Genetic Epidemiology (Epidemiology)
Qualification
Source: Self-asserted source
Ines Barroso

University of Cambridge: Cambridge, Cambridgeshire, GB

1996-06 | PhD Human Molecular Genetics (Pathology)
Qualification
Source: Self-asserted source
Ines Barroso

University of Lisbon: Lisbon, Lisboa, PT

1992-07 | BSc. Biology (Faculty of Science)
Education
Source: Self-asserted source
Ines Barroso

Professional activities (10)

Genetics Society: London, GB

Membership
Source: Self-asserted source
Ines Barroso

European Association for the Study of Diabetes: Dusseldorf, Nordrhein-Westfalen, DE

Membership
Source: Self-asserted source
Ines Barroso

Diabetes UK: London, GB

Membership
Source: Self-asserted source
Ines Barroso

American Society of Human Genetics: Bethesda, Maryland, US

Membership
Source: Self-asserted source
Ines Barroso

American Diabetes Association: Alexandria, VA, US

Membership
Source: Self-asserted source
Ines Barroso

Wellcome Trust: London, London, GB

2021-01-01 to present | Henry Dale Interview Panel member
Invited position
Source: Self-asserted source
Ines Barroso

Novo Nordisk Foundation: Copenhagen, DK

2020-06 to present | SAB Member
Invited position
Source: Self-asserted source
Ines Barroso

Diabetes UK: London, GB

2019-05 to present | Member (IDia Faculty (Innovators in Diabetes))
Invited position
Source: Self-asserted source
Ines Barroso

Diabetes UK: London, GB

2019-03 to present | Research Committee Member
Invited position
Source: Self-asserted source
Ines Barroso

Faculty of 1000 Ltd: London, London, GB

2017-01 to present | Faculty member (Computational Genomics & Genetic Analyses)
Invited position
Source: Self-asserted source
Ines Barroso

Funding (3)

Wellcome Trust Sanger Institute

2016-10 to 2021-09 | Grant
Wellcome Trust Sanger Institute (London, GB)
GRANT_NUMBER:

206194

Source: Self-asserted source
Ines Barroso
grade
Preferred source (of 2)‎

Wellcome Trust Sanger Institute

2011-10 to 2016-09 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

98051

Source: Self-asserted source
Ines Barroso

10,000 UK Genomes Sequences

2010-04 to 2013-04 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

091310/Z/10/Z

Source: Self-asserted source
Ines Barroso

Works (50 of 229)

Items per page:
Page 1 of 5

Combining functional annotation and multi-trait fine-mapping methods improves fine-mapping resolution at glycaemic trait loci

2024-11-15 | Preprint
Contributors: Jana Soenksen; Ji Chen; Arushi Varshney; Susan Martin; Stephen C. J. Parker; Andrew P. Morris; Jennifer L. Asimit; Inês Barroso
Source: check_circle
Crossref

Immunometabolic Blood Biomarkers of Developmental Trajectories of Depressive Symptoms: Findings From the ALSPAC Birth Cohort

2024-07-12 | Preprint
Contributors: Ruby S. M. Tsang; Daniel Stow; Alex S. F. Kwong; Nicholas A. Donnelly; Holly Fraser; Inês A. Barroso; Peter A. Holmans; Michael J. Owen; Megan L. Wood; Marianne B. M. van den Bree et al.
Source: check_circle
Crossref

Leveraging information between multiple population groups and traits improves fine-mapping resolution

Nature Communications
2023-11-10 | Journal article
Contributors: Feng Zhou; Opeyemi Soremekun; Tinashe Chikowore; Segun Fatumo; Inês Barroso; Andrew P. Morris; Jennifer L. Asimit
Source: check_circle
Crossref

Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization [version 1; peer review: 2 approved]

2023-10-20 | Journal article
Part of ISSN: 2398-502X
Funded by GRANT_NUMBER:

095101

Funded by GRANT_NUMBER:

200837

Contributors: Sara M. Willems; Natasha H. J. Ng; Juan Fernandez; Rebecca S. Fine; Eleanor Wheeler; Jennifer Wessel; Hidetoshi Kitajima; Gaelle Marenne; Xueling Sim; Hanieh Yaghootkar et al.
Source: check_circle
Wellcome Open Research

Correction to: The impact of population-level HbA1c screening on reducing diabetes diagnostic delay in middle-aged adults: a UK Biobank analysis

Diabetologia
2023-08 | Journal article
Contributors: Katherine G. Young; Andrew P. McGovern; Inês Barroso; Andrew T. Hattersley; Angus G. Jones; Beverley M. Shields; Nicholas J. Thomas; John M. Dennis
Source: check_circle
Crossref

HbA1c screening for the diagnosis of diabetes. Reply to Brož J, Brabec M, Krollová P et al [letter]

Diabetologia
2023-08 | Journal article
Contributors: Katherine G. Young; Andrew P. McGovern; Inês Barroso; Andrew T. Hattersley; Angus G. Jones; Beverley M. Shields; Nicholas J. Thomas; John M. Dennis
Source: check_circle
Crossref

Leveraging information between multiple population groups and traits improves fine-mapping resolution

2023-06-01 | Preprint
Contributors: Feng Zhou; Opeyemi Soremekun; Tinashe Chikowore; Segun Fatumo; Inês Barroso; Andrew P Morris; Jennifer L Asimit
Source: check_circle
Crossref

The impact of population-level HbA1c screening on reducing diabetes diagnostic delay in middle-aged adults: a UK Biobank analysis

Diabetologia
2023-02 | Journal article
Contributors: Katherine G. Young; Andrew P. McGovern; Inês Barroso; Andrew T. Hattersley; Angus G. Jones; Beverley M. Shields; Nicholas J. Thomas; John M. Dennis
Source: check_circle
Crossref

Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis

JNCI: Journal of the National Cancer Institute
2022-05-09 | Journal article
Contributors: Neil Murphy; Mingyang Song; Nikos Papadimitriou; Robert Carreras-Torres; Claudia Langenberg; Richard M Martin; Konstantinos K Tsilidis; Inês Barroso; Ji Chen; Timothy M Frayling et al.
Source: check_circle
Crossref

An Expanded Genome-Wide Association Study of Fructosamine Levels Identifies RCN3 as a Replicating Locus and Implicates FCGRT as the Effector Transcript

Diabetes
2022-02-01 | Journal article
Contributors: Fernando Riveros-Mckay; David Roberts; Emanuele Di Angelantonio; Bing Yu; Nicole Soranzo; John Danesh; Elizabeth Selvin; Adam S. Butterworth; Inês Barroso
Source: check_circle
Crossref

The importance of increasing population diversity in genetic studies of type 2 diabetes and related glycaemic traits

Diabetologia
2021-12-30 | Journal article
Contributors: Inês Barroso
Source: check_circle
Crossref

Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila

PLOS Biology
2021-11-08 | Journal article
Contributors: Neha Agrawal; Nicolas Tapon; Katherine Lawler; Catherine M. Davidson; Julia M. Keogh; Robert Legg; Inês Barroso; I. Sadaf Farooqi; Andrea H. Brand
Source: check_circle
Crossref

The flashfm approach for fine-mapping multiple quantitative traits

Nature Communications
2021-10-22 | Journal article
Contributors: N. Hernández; J. Soenksen; P. Newcombe; M. Sandhu; I. Barroso; C. Wallace; J. L. Asimit
Source: check_circle
Crossref

Flashfm: A Flexible and Shared Information Fine-mapping Approach for Multiple Quantitative Traits

2021-04-11 | Preprint
Contributors: N Hernández; J Soenksen; P Newcombe; M Sandhu; I Barroso; C Wallace; J Asimit
Source: check_circle
Crossref

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.

Nature communications
2021-01-05 | Journal article
Source: Self-asserted source
Ines Barroso

Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study.

Scientific data
2020-11-13 | Journal article
Source: Self-asserted source
Ines Barroso

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits.

PLoS genetics
2020-10-12 | Journal article
Source: Self-asserted source
Ines Barroso

Genome-wide association study identifies 48 common genetic variants associated with handedness

Nature Human Behaviour
2020-09-28 | Journal article
Contributors: Gabriel Cuellar-Partida; Joyce Y. Tung; Nicholas Eriksson; Eva Albrecht; Fazil Aliev; Ole A. Andreassen; Inês Barroso; Jacques S. Beckmann; Marco P. Boks; Dorret I. Boomsma et al.
Source: check_circle
Crossref

Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections.

Nature communications
2020-07-31 | Journal article
Source: Self-asserted source
Ines Barroso

Human BDNF/TrkB variants impair hippocampal synaptogenesis and associate with neurobehavioural abnormalities.

Scientific reports
2020-06-03 | Journal article
Source: Self-asserted source
Ines Barroso

Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription.

Cell metabolism
2020-06-01 | Journal article
Source: Self-asserted source
Ines Barroso

The influence of rare variants in circulating metabolic biomarkers.

PLoS genetics
2020-03-09 | Journal article
Source: Self-asserted source
Ines Barroso

Genome-wide scale analyses identify novel BMI genotype-environment interactions using a conditional false discovery rate

2020-01-23 | Preprint
Contributors: R. Moore; L. Georgatou-Politou; J. Liley; O. Stegle; I. Barroso
Source: check_circle
Crossref

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

2019-10-03 | Other
Contributors: Natasha H J Ng; Sara M Willems; Anna L Gloyn; Inês Barroso
Source: check_circle
Crossref

Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa.

Cell
2019-10-01 | Journal article
Source: Self-asserted source
Ines Barroso

Genomics of disease risk in globally diverse populations

Nature Reviews Genetics
2019-09 | Journal article
Contributors: Deepti Gurdasani; Inês Barroso; Eleftheria Zeggini; Manjinder S. Sandhu
Source: check_circle
Crossref

Author Correction: Genomics of disease risk in globally diverse populations

Nature Reviews Genetics
2019-09-03 | Journal article
Contributors: Deepti Gurdasani; Inês Barroso; Eleftheria Zeggini; Manjinder S. Sandhu
Source: check_circle
Crossref

Crucial Role of the SH2B1 PH Domain for the Control of Energy Balance.

Diabetes
2019-08-22 | Journal article
Source: Self-asserted source
Ines Barroso

Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals.

Scientific reports
2019-07-01 | Journal article
Source: Self-asserted source
Ines Barroso

Genome-wide association study of type 2 diabetes in Africa.

Diabetologia
2019-05-02 | Journal article
Source: Self-asserted source
Ines Barroso

A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development.

American journal of human genetics
2019-04-18 | Journal article
Source: Self-asserted source
Ines Barroso

The Genetic Basis of Metabolic Disease.

Cell
2019-03-01 | Journal article
Source: Self-asserted source
Ines Barroso

Disentangling the genetics of lean mass.

The American journal of clinical nutrition
2019-02-01 | Journal article
Source: Self-asserted source
Ines Barroso
grade
Preferred source (of 2)‎

A linear mixed-model approach to study multivariate gene–environment interactions

Nature Genetics
2019-01-26 | Journal article
Contributors: Rachel Moore; Francesco Paolo Casale; Marc Jan Bonder; Danilo Horta; Lude Franke; Inês Barroso; Oliver Stegle
Source: check_circle
Crossref

Mendelian Randomization Analysis of Hemoglobin A<sub>1c</sub> as a Risk Factor for Coronary Artery Disease.

Diabetes care
2019-01-18 | Journal article
Source: Self-asserted source
Ines Barroso

Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance.

Cell
2019-01-17 | Journal article
Source: Self-asserted source
Ines Barroso

Bullying investigations need a code of conduct.

Nature
2019-01-01 | Journal article
Source: Self-asserted source
Ines Barroso

Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits.

Nature communications
2018-11 | Journal article
Contributors: Gilly A; Suveges D; Kuchenbaecker K; Pollard M; Southam L; Hatzikotoulas K; Farmaki AE; Bjornland T; Waples R; Appel EVR et al.
Source: Self-asserted source
Ines Barroso via Europe PubMed Central

DNA Polymerase Epsilon Deficiency Causes IMAGe Syndrome with Variable Immunodeficiency.

American journal of human genetics
2018-11 | Journal article
Contributors: Logan CV; Murray JE; Parry DA; Robertson A; Bellelli R; Tarnauskaitė Ž; Challis R; Cleal L; Borel V; Fluteau A et al.
Source: Self-asserted source
Ines Barroso via Europe PubMed Central

The influence of rare variants in circulating metabolic biomarkers

2018-11 | Other
OTHER-ID:

PPR63251

Contributors: Riveros Mckay Aguilera F; Oliver-Williams C; Karthikeyan S; Walter K; Kundu K; Ouwehand WH; Roberts D; Di Angelantonio E; Soranzo N; Danesh J et al.
Source: Self-asserted source
Ines Barroso via Europe PubMed Central

Genome-Wide Sequence Analysis of Kaposi Sarcoma-Associated Herpesvirus Shows Diversification Driven by Recombination

The Journal of Infectious Diseases
2018-10-20 | Journal article
Contributors: Neneh Sallah; Anne L Palser; Simon J Watson; Nazzarena Labo; Gershim Asiki; Vickie Marshall; Robert Newton; Denise Whitby; Paul Kellam; Inês Barroso
Source: check_circle
Crossref

ProxECAT: Proxy External Controls Association Test. A new case-control gene region association test using allele frequencies from public controls

PLOS Genetics
2018-10-16 | Journal article
Contributors: Audrey E. Hendricks; Ingrid Borecki; Stephen C. Billups; Hamish N. C. Pike; I. Sadaf Farooqi; Eleftheria Zeggini; Stephanie A. Santorico; Inês Barroso; Josée Dupuis
Source: check_circle
Crossref

Genome-wide scan and fine-mapping of rare nonsynonymous associations implicates intracellular lipolysis genes in fat distribution and cardio-metabolic risk

2018-07 | Other
OTHER-ID:

PPR45419

Contributors: Lotta LA; Dong L; Li C; Patel S; Stewart ID; Lim K; Day FR; Wheeler E; Glastonbury CA; Van de Streek M et al.
Source: Self-asserted source
Ines Barroso via Europe PubMed Central

Editorial overview: Molecular and genetic basis of [metabolic] disease: Genes, glucose, glycerol and girth: metabolism in our DNA.

Current opinion in genetics & development
2018-06 | Journal article
Contributors: Barroso I; Florez JC
Source: Self-asserted source
Ines Barroso via Europe PubMed Central

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Nature genetics
2018-05 | Journal article
Contributors: Turcot V; Lu Y; Highland HM; Schurmann C; Justice AE; Fine RS; Bradfield JP; Esko T; Giri A; Graff M et al.
Source: Self-asserted source
Ines Barroso via Europe PubMed Central
grade
Preferred source (of 3)‎

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

Nature genetics
2018-04 | Journal article
Contributors: Mahajan A; Wessel J; Willems SM; Zhao W; Robertson NR; Chu AY; Gan W; Kitajima H; Taliun D; Rayner NW et al.
Source: Self-asserted source
Ines Barroso via Europe PubMed Central

Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

2018-03 | Other
OTHER-ID:

PPR17414

Contributors: Gilly A; Suveges D; Kuchenbaecker K; Pollard MO; Southam L; Hatzikotoulas K; Farmaki A; Bjornland T; Waples R; Appel EV et al.
Source: Self-asserted source
Ines Barroso via Europe PubMed Central

ADCY3, neuronal primary cilia and obesity.

Nature genetics
2018-02 | Journal article
Contributors: Barroso I
Source: Self-asserted source
Ines Barroso via Europe PubMed Central

A linear mixed model approach to study multivariate gene-environment interactions

2018-02-25 | Other
Contributors: Rachel Moore; Francesco Paolo Casale; Marc Jan Bonder; Danilo Horta; Lude Franke; Inês Barroso; Oliver Stegle
Source: check_circle
Crossref

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Scientific data
2018-01 | Journal article
Contributors: Flannick J; Fuchsberger C; Mahajan A; Teslovich TM; Agarwala V; Gaulton KJ; Caulkins L; Koesterer R; Ma C; Moutsianas L et al.
Source: Self-asserted source
Ines Barroso via Europe PubMed Central
Items per page:
Page 1 of 5

Peer review (24 reviews for 5 publications/grants)

Review activity for Faculty Opinions (19)
Review activity for Nature communications (1)
Review activity for Nature genetics. (2)
Review activity for Nature metabolism. (1)
Review activity for PLOS genetics. (1)