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Employment (3)

National Institutes of Health: Bethesda, MD, US

2017 to present | Staff Scientist (NIAID)
Employment
Source: Self-asserted source
Alexandra Ortiz

National Institutes of Health: Bethesda, Maryland, US

2015 to 2017 | Research Fellow
Employment
Source: Self-asserted source
Alexandra Ortiz

National Institutes of Health: Bethesda, Maryland, US

2012 to 2015 | Post-Doctoral Fellow
Employment
Source: Self-asserted source
Alexandra Ortiz

Education and qualifications (2)

University of Pennsylvania: Philadelphia, Pennsylvania, US

2006 to 2012 | PhD
Education
Source: Self-asserted source
Alexandra Ortiz

University of Virginia: Charlottesville, Virginia, US

2000 to 2004 | B.A.
Education
Source: Self-asserted source
Alexandra Ortiz

Works (14)

Untangling the role of the microbiome across the stages of HIV disease.

Current opinion in HIV and AIDS
2024-07-24 | Journal article
DOI: 10.1097/coh.0000000000000870
PMID: 38935047
PMC: PMC11305932
Contributors: Ortiz AM; Brenchley JM
Source: Self-asserted source
Alexandra Ortiz

2-Hydroxypropyl-β-Cyclodextrin Treatment Induces Modest Immune Activation in Healthy Rhesus Macaques.

Journal of virology
2023-06-20 | Journal article | Author
DOI: 10.1128/jvi.00600-23
PMID: 37338342
PMC: PMC10373544
Contributors: Alexandra Ortiz; Castello Casta F; Andrew R. Rahmberg; Markowitz TE; Kelsie Brooks; Simpson J; Brenchley JM
Source: Self-asserted source
Alexandra Ortiz

Experimental bacterial dysbiosis with consequent immune alterations increase intrarectal SIV acquisition susceptibility.

Cell reports
2023-01-23 | Journal article
DOI: 10.1016/j.celrep.2023.112020
PMID: 36848230
PMC: PMC9989505
Contributors: Ortiz AM; Baker PJ; Charlotte Langner; Simpson J; Stacy A; Flynn JK; Starke CE; Vinton CL; Fennessey CM; Belkaid Y et al.
Source: Self-asserted source
Alexandra Ortiz

Butyrate administration is not sufficient to improve immune reconstitution in antiretroviral-treated SIV-infected macaques.

Scientific reports
2022-05-06 | Journal article
DOI: 10.1038/s41598-022-11122-x
PMID: 35523797
PMC: PMC9076870
Contributors: Ortiz AM; Simpson J; Charlotte Langner; Baker PJ; Aguilar C; Kelsie Brooks; Flynn JK; Vinton CL; Andrew R. Rahmberg; Hickman HD et al.
Source: Self-asserted source
Alexandra Ortiz

Microbiome Studies in Non-human Primates.

Current HIV/AIDS reports
2021-11-04 | Journal article
DOI: 10.1007/s11904-021-00584-9
PMID: 34735686
PMC: PMC8567131
Contributors: Jason Brenchley; Ortiz AM
Source: Self-asserted source
Alexandra Ortiz

Luminal microvesicles uniquely influence translocating bacteria after SIV infection.

Mucosal immunology
2021-03-17 | Journal article
DOI: 10.1038/s41385-021-00393-8
PMID: 33731830
PMC: PMC8225551
Contributors: Flynn JK; Charlotte Langner; Karmele EP; Baker PJ; Pei L; Gorfu EG; Bochart RM; Santiana M; Smelkinson MG; Nutman TB et al.
Source: Self-asserted source
Alexandra Ortiz

Antiretroviral Therapy Administration in Healthy Rhesus Macaques Is Associated with Transient Shifts in Intestinal Bacterial Diversity and Modest Immunological Perturbations.

Journal of virology
2019-08-28 | Journal article | Author
DOI: 10.1128/jvi.00472-19
PMID: 31270225
PMC: PMC6714794
Contributors: Alexandra Ortiz; Flynn JK; Sarah DiNapoli; Sortino O; Ivan Vujkovic-Cvijin; Belkaid Y; Sereti I; Jason Brenchley
Source: Self-asserted source
Alexandra Ortiz

Experimental microbial dysbiosis does not promote disease progression in SIV-infected macaques.

Nature medicine
2018-07-30 | Journal article | Author
DOI: 10.1038/s41591-018-0132-5
PMID: 30061696
PMC: PMC6129204
Contributors: Alexandra Ortiz; Flynn JK; Sarah DiNapoli; Ivan Vujkovic-Cvijin; Carly Elizabeth Starke; Lai SH; Long ME; Sortino O; Vinton CL; Mudd JC et al.
Source: Self-asserted source
Alexandra Ortiz

Microbial translocation: translating simian immunodeficiency virus to HIV.

Current opinion in HIV and AIDS
2018-01-01 | Journal article
DOI: 10.1097/coh.0000000000000424
PMID: 29028666
PMC: PMC5937926
Contributors: Ortiz AM; Jason Brenchley
Source: Self-asserted source
Alexandra Ortiz

Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys.

PloS one
2016-05-26 | Journal article
DOI: 10.1371/journal.pone.0156352
PMID: 27227993
PMC: PMC4881966
Contributors: Ortiz AM; Carnathan DG; Yu J; Sheehan KM; Kim P; Arnold Reynaldi; Vanderford TH; Klatt NR; Jason Brenchley; Miles Davenport et al.
Source: Self-asserted source
Alexandra Ortiz

IL-21 and probiotic therapy improve Th17 frequencies, microbial translocation, and microbiome in ARV-treated, SIV-infected macaques.

Mucosal immunology
2015-08-19 | Journal article
DOI: 10.1038/mi.2015.75
PMID: 26286233
PMC: PMC4760912
Contributors: Ortiz AM; Klase ZA; Sarah DiNapoli; Ivan Vujkovic-Cvijin; Carmack K; Perkins MR; Calantone N; Vinton CL; Riddick NE; Gallagher J et al.
Source: Self-asserted source
Alexandra Ortiz

Macrophages Are Phenotypically and Functionally Diverse across Tissues in Simian Immunodeficiency Virus-Infected and Uninfected Asian Macaques.

Journal of virology
2015-03-18 | Journal article
DOI: 10.1128/jvi.00005-15
PMID: 25787286
PMC: PMC4442434
Contributors: Ortiz AM; Sarah DiNapoli; Jason Brenchley
Source: Self-asserted source
Alexandra Ortiz

Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques.

The Journal of clinical investigation
2011-10-17 | Journal article
DOI: 10.1172/jci46023
PMID: 22005304
PMC: PMC3204830
Contributors: Ortiz AM; Klatt NR; Li B; Yi Y; Tabb B; Xingpei Hao; Sternberg L; Lawson B; Carnathan PM; Cramer EM et al.
Source: Self-asserted source
Alexandra Ortiz

Immunopathogenesis of AIDS.

Current infectious disease reports
2009-05-01 | Journal article
DOI: 10.1007/s11908-009-0035-1
PMID: 19366567
Contributors: Ortiz AM; Silvestri G
Source: Self-asserted source
Alexandra Ortiz

Peer review (6 reviews for 3 publications/grants)

Review activity for Journal of obstetrics and gynaecology Canada. (1)
Review activity for PloS one. (1)
Review activity for PLOS pathogens : (4)
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