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Scopus Author ID: 6603854624

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University of California: San Francisco, CA, US

2008-07 to present | Professional Researcher (Pathology)
Employment
Source: Self-asserted source
Philippe Gascard

Works (50 of 62)

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Loss of PPARγ activity characterizes early protumorigenic stromal reprogramming and dictates the therapeutic window of opportunity

Proceedings of the National Academy of Sciences
2023-10-17 | Journal article
DOI: 10.1073/pnas.2303774120
Contributors: Joseph A. Caruso; Xianhong Wang; Lyndsay M. Murrow; Carlos Ivan Rodriguez; Chira Chen-Tanyolac; Lisa Vu; Yunn-Yi Chen; Philippe Gascard; Zev J. Gartner; Karla Kerlikowske et al.
Source: check_circle
Crossref

Stromal directives can control cancer

Science
2019 | Journal article
DOI: 10.1126/science.aaw2368
EID:

2-s2.0-85068979523
Contributors: Tlsty, T.D.; Gascard, P.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Carcinoma-associated fibroblasts: Orchestrating the composition of malignancy

Genes and Development
2016 | Journal article
DOI: 10.1101/gad.279737.116
EID:

2-s2.0-84965082206
Contributors: Gascard, P.; Tlsty, T.D.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

SOX2, OCT3/4 and NANOG expression and cellular plasticity in rare human somatic cells requires CD73

Cellular Signalling
2016 | Journal article
DOI: 10.1016/j.cellsig.2016.09.008
EID:

2-s2.0-84991500799
Contributors: Pan, D.; Roy, S.; Gascard, P.; Zhao, J.; Chen-Tanyolac, C.; Tlsty, T.D.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Epigenetic and transcriptional determinants of the human breast

Nature Communications
2015 | Journal article
DOI: 10.1038/ncomms7351
EID:

2-s2.0-84923348351
Contributors: Gascard, P.; Bilenky, M.; Sigaroudinia, M.; Zhao, J.; Li, L.; Carles, A.; Delaney, A.; Tam, A.; Kamoh, B.; Cho, S. et al.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Integrative analysis of 111 reference human epigenomes

Nature
2015 | Journal article
DOI: 10.1038/nature14248
EID:

2-s2.0-84923362619
Contributors: Roadmap Epigenomics Consortium; Kundaje, A.; Meuleman, W.; Ernst, J.; Bilenky, M.; Yen, A.; Heravi-Moussavi, A.; Kheradpour, P.; Zhang, Z.; Wang, J. et al.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Intermediate DNA methylation is a conserved signature of genome regulation

Nature Communications
2015 | Journal article
DOI: 10.1038/ncomms7363
EID:

2-s2.0-84923345958
Contributors: Elliott, G.; Hong, C.; Xing, X.; Zhou, X.; Li, D.; Coarfa, C.; Bell, R.J.A.; Maire, C.L.; Ligon, K.L.; Sigaroudinia, M. et al.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Novel insights from 3D models: The pivotal role of physical symmetry in epithelial organization

Scientific Reports
2015 | Journal article
DOI: 10.1038/srep15153
EID:

2-s2.0-84944345247
Contributors: Kurup, A.; Ravindranath, S.; Tran, T.; Keating, M.; Gascard, P.; Valdevit, L.; Tlsty, T.D.; Botvinick, E.L.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Towards aspirin-inspired self-immolating molecules which target the cyclooxygenases

Organic and Biomolecular Chemistry
2015 | Journal article
DOI: 10.1039/c5ob01805f
EID:

2-s2.0-84947465913
Contributors: Drake, C.R.; Estévez-Salmerón, L.; Gascard, P.; Shen, Y.; Tlsty, T.D.; Jones, E.F.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Phosphatidylinositol-4,5 bisphosphate (PIP<inf>2</inf>) inhibits apo-calmodulin binding to protein 4.1

Biochemical and Biophysical Research Communications
2014 | Journal article
DOI: 10.1016/j.bbrc.2014.02.121
EID:

2-s2.0-84897992446
Contributors: Nunomura, W.; Gascard, P.; Wakui, H.; Takakuwa, Y.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Regulatory network decoded from epigenomes of surface ectoderm-derived cell types

Nature Communications
2014 | Journal article
DOI: 10.1038/ncomms6442
EID:

2-s2.0-84923292574
Contributors: Lowdon, R.F.; Zhang, B.; Bilenky, M.; Mauro, T.; Li, D.; Gascard, P.; Sigaroudinia, M.; Farnham, P.J.; Bastian, B.C.; Tlsty, T.D. et al.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

A physical sciences network characterization of non-tumorigenic and metastatic cells

Scientific Reports
2013 | Journal article
DOI: 10.1038/srep01449
EID:

2-s2.0-84878282427
Contributors: Agus, D.B.; Alexander, J.F.; Arap, W.; Ashili, S.; Aslan, J.E.; Austin, R.H.; Backman, V.; Bethel, K.J.; Bonneau, R.; Chen, W.-C. et al.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Coordinate Transcriptional and Translational Repression of p53 by TGF-β1 Impairs the Stress Response

Molecular Cell
2013 | Journal article
DOI: 10.1016/j.molcel.2013.04.029
EID:

2-s2.0-84878177599
Contributors: López-Díaz, F.; Gascard, P.; Balakrishnan, S.; Zhao, J.; delRincon, S.; Spruck, C.; Tlsty, T.; Emerson, B.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape

Nature Genetics
2013 | Journal article
DOI: 10.1038/ng.2649
EID:

2-s2.0-84879611157
Contributors: Xie, M.; Hong, C.; Zhang, B.; Lowdon, R.F.; Xing, X.; Li, D.; Zhou, X.; Lee, H.J.; Maire, C.L.; Ligon, K.L. et al.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&amp;M algorithm

Genome Research
2013 | Journal article
DOI: 10.1101/gr.156539.113
EID:

2-s2.0-84883668746
Contributors: Zhang, B.; Zhou, Y.; Lin, N.; Lowdon, R.F.; Hong, C.; Nagarajan, R.P.; Cheng, J.B.; Li, D.; Stevens, M.; Lee, H.J. et al.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Proteins: Ion transporters in check

Journal of Proteomics and Bioinformatics
2013 | Journal article
DOI: 10.4172/jpb.S4-004
EID:

2-s2.0-84887283983
Contributors: Nunomura, W.; Wakui, H.; Takakuwa, Y.; Gascard, P.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Rare somatic cells from human breast tissue exhibit extensive lineage plasticity

Proceedings of the National Academy of Sciences of the United States of America
2013 | Journal article
DOI: 10.1073/pnas.1218682110
EID:

2-s2.0-84875268294
Contributors: Roy, S.; Gascard, P.; Dumont, N.; Zhao, J.; Pan, D.; Petrie, S.; Margeta, M.; Tlsty, T.D.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Characterization of cytoskeletal protein 4.1R interaction with NHE1 (Na<sup>+</sup> /H<sup>+</sup> exchanger isoform 1)

Biochemical Journal
2012 | Journal article
DOI: 10.1042/BJ20120535
EID:

2-s2.0-84865588105
Contributors: Nunomura, W.; Denker, S.P.; Barber, D.L.; Takakuwa, Y.; Gascard, P.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Isoforms of protein 4.1 are differentially distributed in heart muscle cells: Relation of 4.1R and 4.1G to components of the Ca<sup>2+</sup> homeostasis system

Experimental Cell Research
2012 | Journal article
DOI: 10.1016/j.yexcr.2012.03.003
EID:

2-s2.0-84862023004
Contributors: Pinder, J.C.; Taylor-Harris, P.M.; Bennett, P.M.; Carter, E.; Hayes, N.V.L.; King, M.D.A.; Holt, M.R.; Maggs, A.M.; Gascard, P.; Baines, A.J.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

Nature
2012 | Journal article
DOI: 10.1038/nature10933
EID:

2-s2.0-84862526929
Contributors: Shah, S.P.; Roth, A.; Goya, R.; Oloumi, A.; Ha, G.; Zhao, Y.; Turashvili, G.; Ding, J.; Tse, K.; Haffari, G. et al.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Insights into the function of the unstructured N-terminal domain of proteins 4.1R and 4.1G in erythropoiesis

International Journal of Cell Biology
2011 | Journal article
DOI: 10.1155/2011/943272
EID:

2-s2.0-81555220907
Contributors: Nunomura, W.; Gascard, P.; Takakuwa, Y.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Similarities and differences in the structure and function of 4.1G and 4.1R<sup>135</sup>, two protein 4.1 paralogues expressed in erythroid cells

Biochemical Journal
2010 | Journal article
DOI: 10.1042/BJ20100041
EID:

2-s2.0-78649579937
Contributors: Nunomura, W.; Kinoshita, K.; Parra, M.; Gascard, P.; An, X.; Mohandas, N.; Takakuwa, Y.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition

Cancer Research
2009 | Journal article
DOI: 10.1158/0008-5472.CAN-08-3389
EID:

2-s2.0-58349091262
Contributors: Mirzoeva, O.K.; Das, D.; Heiser, L.M.; Bhattacharya, S.; Siwak, D.; Gendelman, R.; Bayani, N.; Wang, N.J.; Neve, R.M.; Guan, Y. et al.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Ionizing radiation predisposes nonmalignant human mammary epithelial cells to undergo transforming growth factor β-induced epithelial to mesenchymal transition

Cancer Research
2007 | Journal article
DOI: 10.1158/0008-5472.CAN-07-1294
EID:

2-s2.0-34548863660
Contributors: Andarawewa, K.L.; Erickson, A.C.; Chou, W.S.; Costes, S.V.; Gascard, P.; Mott, J.D.; Bissell, M.J.; Barcellos-Hoff, M.H.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Effect of complete protein 4.1R deficiency on ion transport properties of murine erythrocytes

American Journal of Physiology - Cell Physiology
2006 | Journal article
DOI: 10.1152/ajpcell.00436.2005
EID:

2-s2.0-33751120184
Contributors: Rivera, A.; De Franceschi, L.; Peters, L.L.; Gascard, P.; Mohandas, N.; Brugnara, C.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

New insights into potential functions for the protein 4.1 superfamily of proteins in kidney epithelium

Frontiers in Bioscience
2006 | Journal article
EID:

2-s2.0-32844458453
Contributors: Calinisan, V.; Gravem, D.; Chen, R.P.-H.; Brittin, S.; Mohandas, N.; Lecomte, M.-C.; Gascard, P.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Development of a targeted transgenesis strategy in highly differentiated cells: A powerful tool for functional genomic analysis

Journal of Biotechnology
2005 | Journal article
DOI: 10.1016/j.jbiotec.2004.10.014
EID:

2-s2.0-12344337368
Contributors: Puttini, S.; Ouvrard-Pascaud, A.; Palais, G.; Beggah, A.T.; Gascard, P.; Cohen-Tannoudji, M.; Babinet, C.; Blot-Chabaud, M.; Jaisser, F.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Evidence for a protective role of the Gardos channel against hemolysis in murine spherocytosis

Blood
2005 | Journal article
DOI: 10.1182/blood-2005-01-0368
EID:

2-s2.0-23744504966
Contributors: De Franceschi, L.; Rivera, A.; Fleming, M.D.; Honczarenko, M.; Peters, L.L.; Gascard, P.; Mohandas, N.; Brugnara, C.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Differential domain evolution and complex RNA processing in a family of paralogous EPB41 (protein 4.1) genes facilitate expression of diverse tissue-specific isoforms

Genomics
2004 | Journal article
DOI: 10.1016/j.ygeno.2004.06.004
EID:

2-s2.0-4744346667
Contributors: Parra, M.; Gee, S.; Chan, N.; Ryaboy, D.; Dubchak, I.; Mohandas, N.; Gascard, P.D.; Conboy, J.G.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Putative tumor suppressor protein 4.1B is differentially expressed in kidney and brain via alternative promoters and 5′ alternative splicing

Biochimica et Biophysica Acta - Gene Structure and Expression
2004 | Journal article
DOI: 10.1016/j.bbaexp.2004.08.006
EID:

2-s2.0-5444261295
Contributors: Gascard, P.; Parra, M.K.; Zhao, Z.; Calinisan, V.R.; Nunomura, W.; Rivkees, S.A.; Mohandas, N.; Conboy, J.G.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Distinct distribution of specific members of protein 4.1 gene family in the mouse nephron

Kidney International
2003 | Journal article
DOI: 10.1046/j.1523-1755.2003.00870.x
EID:

2-s2.0-0037377642
Contributors: Ramez, M.; Blot-Chabaud, M.; Cluzeaud, F.; Chanan, S.; Patterson, M.; Walensky, L.D.; Marfatia, S.; Baines, A.J.; Chasis, J.A.; Conboy, J.G. et al.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Identification of a third Protein 4.1 tumor suppressor, Protein 4.1R, in meningioma pathogenesis

Neurobiology of Disease
2003 | Journal article
DOI: 10.1016/S0969-9961(03)00071-8
EID:

2-s2.0-0042093562
Contributors: Robb, V.A.; Li, W.; Gascard, P.; Perry, A.; Mohandas, N.; Gutmann, D.H.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Nucleolar localization of RPS19 protein in normal cells and mislocalization due to mutations in the nucleolar localization signals in 2 Diamond-Blackfan anemia patients: Potential insights into pathophysiology

Blood
2003 | Journal article
EID:

2-s2.0-0038383284
Contributors: Da Costa, L.; Tchernia, G.; Gascard, P.; Lo, A.; Meerpohl, J.; Niemeyer, C.; Chasis, J.-A.; Fixler, J.; Mohandas, N.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Erratum: What do mouse gene knockouts tell us about the structure and function of the red cell membrane? (Baillière's Clinical Haematology (1999) vol. 12 (605-620))

Best Practice and Research: Clinical Haematology
2001 | Journal article
DOI: 10.1053/beha.2001.0176
EID:

2-s2.0-14244270514
Contributors: Mohandas, N.; Gascard, P.; Peters, L.; Barker, J.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Structural and functional characterization of protein 4.1R-phosphatidylserine interaction: Potential role in 4.1R sorting within cells

Journal of Biological Chemistry
2001 | Journal article
DOI: 10.1074/jbc.M101364200
EID:

2-s2.0-0035929586
Contributors: An, X.-L.; Takakuwa, Y.; Manno, S.; Han, B.-G.; Gascard, P.; Mohandas, N.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Molecular and functional characterization of protein 4.1B, a novel member of the protein 4.1 family with high level, focal expression in brain

Journal of Biological Chemistry
2000 | Journal article
DOI: 10.1074/jbc.275.5.3247
EID:

2-s2.0-0034603033
Contributors: Parra, M.; Gascard, P.; Walensky, L.D.; Gimm, J.A.; Blackshaw, S.; Chan, N.; Takakuwa, Y.; Berger, T.; Lee, G.; Chasis, J.A. et al.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

New insights into functions of erythroid proteins in nonerythroid cells

Current Opinion in Hematology
2000 | Journal article
DOI: 10.1097/00062752-200003000-00009
EID:

2-s2.0-0033953154
Contributors: Gascard, P.; Mohandas, N.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Deciphering the nuclear import pathway for the cytoskeletal red cell protein 4.1R

Molecular Biology of the Cell
1999 | Journal article
DOI: 10.1091/mbc.10.6.1783
EID:

2-s2.0-0033021961
Contributors: Gascard, P.; Nunomura, W.; Lee, G.; Walensky, L.D.; Krauss, S.W.; Takakuwa, Y.; Chasis, J.A.; Mohandas, N.; Conboy, J.G.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Protein 4.1: The family is getting larger,Proteine 4.1: La famille s'agrandit

Hematologie
1999 | Journal article
EID:

2-s2.0-0033376244
Contributors: Gascard, P.; Choquet, S.; Mohandas, N.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

What do mouse gene knockouts tell us about the structure and function of the red cell membrane?

Bailliere's Best Practice and Research in Clinical Haematology
1999 | Journal article
DOI: 10.1053/beha.1999.0044
EID:

2-s2.0-0033512096
Contributors: Mohandas, N.; Gascard, P.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Characterization of multiple isoforms of protein 4.1R expressed during erythroid terminal differentiation

Blood
1998 | Journal article
EID:

2-s2.0-0032400833
Contributors: Gascard, P.; Lee, G.; Coulombel, L.; Auffray, I.; Lum, M.; Parra, M.; Conboy, J.G.; Mohandas, N.; Chasis, J.A.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Cloning and characterization of 4.1G (EPB41l2), a new member of the skeletal protein 4.1 (EPB41) gene family

Genomics
1998 | Journal article
DOI: 10.1006/geno.1998.5265
EID:

2-s2.0-0000104067
Contributors: Parra, M.; Gascard, P.; Walensky, L.D.; Snyder, S.H.; Mohandas, N.; Conboy, J.G.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Identification of an interaction between the M-band protein skelemin and β-integrin subunits: Colocalization of a skelemin-like protein with β<inf>1</inf>- and β<inf>3</inf>-integrins in non-muscle cells

Journal of Biological Chemistry
1998 | Journal article
DOI: 10.1074/jbc.273.52.35039
EID:

2-s2.0-0032567345
Contributors: Reddy, K.B.; Gascard, P.; Price, M.G.; Negrescu, E.V.; Fox, J.E.B.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Neurobehavioral deficits in mice lacking the erythrocyte membrane cytoskeletal protein 4.1

Current Biology
1998 | Journal article
EID:

2-s2.0-13144255715
Contributors: Walensky, L.D.; Shi, Z.T.; Blackshaw, S.; DeVries, A.C.; Demas, G.E.; Gascard, P.; Nelson, R.J.; Conboy, J.G.; Rubin, E.M.; Snyder, S.H. et al.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

The 13-kD FK506 binding protein, FKBP13, interacts with a novel homologue of the erythrocyte membrane cytoskeletal protein 4.1

Journal of Cell Biology
1998 | Journal article
DOI: 10.1083/jcb.141.1.143
EID:

2-s2.0-0032489868
Contributors: Walensky, L.D.; Gascard, P.; Fields, M.E.; Blackshaw, S.; Conboy, J.G.; Mohandas, N.; Snyder, S.H.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

The FERM domain: A unique module involved in the linkage of cytoplasmic proteins to the membrane

Trends in Biochemical Sciences
1998 | Journal article
DOI: 10.1016/S0968-0004(98)01237-7
EID:

2-s2.0-0031683065
Contributors: Chishti, A.H.; Kim, A.C.; Marfatia, S.M.; Lutchman, M.; Hanspal, M.; Jindal, H.; Liu, S.-C.; Low, P.S.; Rouleau, G.A.; Mohandas, N. et al.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Structural protein 4.1 in the nucleus of human cells: Dynamic rearrangements during cell division

Journal of Cell Biology
1997 | Journal article
DOI: 10.1083/jcb.137.2.275
EID:

2-s2.0-0030992443
Contributors: Krauss, S.W.; Larabell, C.A.; Lockett, S.; Gascard, P.; Penman, S.; Mohandas, N.; Chasis, J.A.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Specific loss of protein kinase activities in senescent erythrocytes

Blood
1996 | Journal article
EID:

2-s2.0-0029794021
Contributors: Jindal, H.K.; Ai, Z.; Gascard, P.; Horton, C.; Cohen, C.M.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Absence of high-affinity band 4.1 binding sites from membranes of glycophorin C- and D-deficient (Leach phenotype) erythrocytes

Blood
1994 | Journal article
EID:

2-s2.0-0028140427
Contributors: Gascard, P.; Cohen, C.M.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier

Cellular distribution of polyphosphoinositides in rat hepatocytes

Cellular Signalling
1993 | Journal article
DOI: 10.1016/0898-6568(93)90052-N
EID:

2-s2.0-0027435922
Contributors: Tran, D.; Gascard, P.; Berthon, B.; Fukami, K.; Takenawa, T.; Giraud, F.; Claret, M.
Source: Self-asserted source
Philippe Gascard via Scopus - Elsevier
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