Personal information

Websites & social links

Brummelkamp group

Keywords

Haploid Genetics

Countries

Netherlands

Activities

Collapse all

Employment (5)

Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis: Amsterdam, Noord-Holland, NL

2017-07 to present | Senior postdoctoral fellow (Dept. of Biochemistry)
Employment
Source: Self-asserted source
Matthijs Raaben

Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis: Amsterdam, Noord-Holland, NL

2013-08 to 2017-07 | Postdoctoral fellow (Dept. of Biochemistry)
Employment
Source: Self-asserted source
Matthijs Raaben

Harvard Medical School: Boston, MA, US

2010-05 to 2013-08 | Postdoctoral fellow (Dept. of Microbiology & Immunobiology)
Employment
Source: Self-asserted source
Matthijs Raaben

Universiteit Utrecht: Utrecht, Utrecht, NL

2009-01 to 2010-04 | Postdoctoral fellow (Dept. of Immunology & infectious Diseases, Virology Division)
Employment
Source: Self-asserted source
Matthijs Raaben

Universiteit Utrecht: Utrecht, Utrecht, NL

2004-11 to 2008-12 | PhD student (Dept. of Immunology & Infectious Diseases, Virology Division)
Employment
Source: Self-asserted source
Matthijs Raaben

Education and qualifications (2)

Universiteit Utrecht: Utrecht, Utrecht, NL

2002-09 to 2004-10 | Master of Science (Immunology & Infectious Diseases, Virology Division)
Education
Source: Self-asserted source
Matthijs Raaben

Universiteit Utrecht: Utrecht, Utrecht, NL

1999-09 to 2002-09 | Bachelor of Science
Education
Source: Self-asserted source
Matthijs Raaben

Funding (1)

BReaking Arenavirus Cell Entry (BRACE)

2015-10 to 2017-10 | Grant
H2020 Marie Skłodowska-Curie Actions (Brussel, BE)
GRANT_NUMBER:

660417
Source: Self-asserted source
Matthijs Raaben

Works (23)

Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis.

Arteriosclerosis, thrombosis, and vascular biology
2017-09 | Journal article
DOI: 10.1161/atvbaha.117.310002
PMID: 28882874
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling.

Nature
2017-06 | Journal article
DOI: 10.1038/nature22376
PMID: 28562590
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles.

mSphere
2016 | Journal article
DOI: 10.1128/msphere.00007-16
PMID: 27303731
PMC: PMC4894689
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Intermediate filaments enable pathogen docking to trigger type 3 effector translocation.

Nature microbiology
2016-03 | Journal article
DOI: 10.1038/nmicrobiol.2016.25
PMID: 27572444
PMC: PMC5006386
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Assays to identify genetic elements affecting phenotype

2015 | Patent
PAT: PCT/NL2016/050381
Source: Self-asserted source
Matthijs Raaben

Identification of potential immunotherapeutic targets in antigen presentation and costimulation networks.

Journal for immunotherapy of cancer
2014 | Journal article
DOI: 10.1186/2051-1426-2-s3-p126
PMC: PMC4288431
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Virus entry. Lassa virus entry requires a trigger-induced receptor switch.

Science (New York, N.Y.)
2014-06 | Journal article
DOI: 10.1126/science.1252480
PMID: 24970085
PMC: PMC4239993
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Deciphering the glycosylome of dystroglycanopathies using haploid screens for lassa virus entry.

Science (New York, N.Y.)
2013-04 | Journal article
DOI: 10.1126/science.1233675
PMID: 23519211
PMC: PMC3919138
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

CD200 receptor controls sex-specific TLR7 responses to viral infection.

PLoS pathogens
2012 | Journal article
DOI: 10.1371/journal.ppat.1002710
PMID: 22615569
PMC: PMC3355091
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Ebola virus entry requires the host-programmed recognition of an intracellular receptor.

The EMBO journal
2012-04 | Journal article
DOI: 10.1038/emboj.2012.53
PMID: 22395071
PMC: PMC3343336
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Methods and assays for treating filoviridae infections

2011 | Patent
PAT: PCT/US2012/022349
Source: Self-asserted source
Matthijs Raaben

The Ebola virus glycoprotein mediates entry via a non-classical dynamin-dependent macropinocytic pathway.

Virology
2011-10 | Journal article
DOI: 10.1016/j.virol.2011.08.009
PMID: 21907381
PMC: PMC3177976
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Ebola virus entry requires the cholesterol transporter Niemann-Pick C1.

Nature
2011-08 | Journal article
DOI: 10.1038/nature10348
PMID: 21866103
PMC: PMC3175325
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

The proteasome inhibitor Velcade enhances rather than reduces disease in mouse hepatitis coronavirus-infected mice.

Journal of virology
2010-08 | Journal article
DOI: 10.1128/jvi.00486-10
PMID: 20484516
PMC: PMC2897637
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

The ubiquitin-proteasome system plays an important role during various stages of the coronavirus infection cycle.

Journal of Virology
2010-08 | Journal article
DOI: 10.1128/jvi.00485-10
PMID: 20484504
PMC: PMC2897594
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Type I interferon receptor-independent and -dependent host transcriptional responses to mouse hepatitis coronavirus infection in vivo.

BMC genomics
2009 | Journal article
DOI: 10.1186/1471-2164-10-350
PMID: 19650917
PMC: PMC2728740
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Non-invasive imaging of mouse hepatitis coronavirus infection reveals determinants of viral replication and spread in vivo.

Cellular microbiology
2009-05 | Journal article
DOI: 10.1111/j.1462-5822.2009.01298.x
PMID: 19215224
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Improved microarray gene expression profiling of virus-infected cells after removal of viral RNA.

BMC genomics
2008 | Journal article
DOI: 10.1186/1471-2164-9-221
PMID: 18479515
PMC: PMC2397413
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Mouse hepatitis coronavirus RNA replication depends on GBF1-mediated ARF1 activation.

PLoS Pathogens
2008-06 | Journal article
DOI: 10.1371/journal.ppat.1000088
PMID: 18551169
PMC: PMC2398782
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Cyclooxygenase activity is important for efficient replication of mouse hepatitis virus at an early stage of infection.

Virology journal
2007 | Journal article
DOI: 10.1186/1743-422x-4-55
PMID: 17555580
PMC: PMC1892777
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Mouse hepatitis coronavirus replication induces host translational shutoff and mRNA decay, with concomitant formation of stress granules and processing bodies.

Cellular microbiology
2007-09 | Journal article
DOI: 10.1111/j.1462-5822.2007.00951.x
PMID: 17490409
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Cooperative involvement of the S1 and S2 subunits of the murine coronavirus spike protein in receptor binding and extended host range.

Journal of virology
2006-11 | Journal article
DOI: 10.1128/jvi.00950-06
PMID: 16956938
PMC: PMC1642182
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central

Targeting non-human coronaviruses to human cancer cells using a bispecific single-chain antibody.

Gene therapy
2005-09 | Journal article
DOI: 10.1038/sj.gt.3302535
PMID: 15843808
Source: Self-asserted source
Matthijs Raaben via Europe PubMed Central
How many people are using ORCID?