Biography

Dr. Rabeh’s research is devoted to the discovery and design of new therapeutic. The mechanistic understanding of the disease-causing protein assists in the discovery and design of small molecule that will function as an activator or inhibitor of the protein target. A focussed approach that uses the proteins structural information and computer simulation to design a specific therapeutics that is biophysically and biochemically tested for its effect on human proteins with medical relevance. Protein targets include human Hexokinase II, Cystic Fibrosis Trans-membrane conductance Regulator (CFTR) ion channel, and Septins GTP-Binding proteins.