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Employment (3)

Vanderbilt University: Nashville, Tennessee, US

2023-01-01 to present | Professor (Molecular Physiology and Biophysics)
Employment
Source: Self-asserted source
Terunaga Nakagawa

Vanderbilt University: Nashville, Tennessee, US

2012 to 2022-12-31 | Associate Professor (Molecular Physiology and Biophysics)
Employment
Source: Self-asserted source
Terunaga Nakagawa

University of California, San Diego: San Diego, US

2005 to 2012 | Assistant Professor (Chemistry and Biochemistry)
Employment
Source: Self-asserted source
Terunaga Nakagawa

Education and qualifications (5)

Massachusetts Institute of Technology: Cambridge, US

2001-07 to 2005-06 | Post doctoral fellow (Picower Center for Learning and Memory)
Education
Source: Self-asserted source
Terunaga Nakagawa

Massachusetts General Hospital: Boston, US

2000-04 to 2001-06 | Post doctoral fellow (Neurobiology)
Education
Source: Self-asserted source
Terunaga Nakagawa

The University of Tokyo: Tokyo, JP

1996-04-01 to 2000-03-31 | PhD (Department of Cell Biology and Anatomy, School of Medicine )
Education
Source: Self-asserted source
Terunaga Nakagawa

The University of Tokyo: Tokyo, JP

1992-04-01 to 1996-03-31 | MD (School of Medicine )
Education
Source: Self-asserted source
Terunaga Nakagawa

The University of Tokyo: Tokyo, JP

1990-04-01 to 1992-03-31 (Arts and Sciences)
Education
Source: Self-asserted source
Terunaga Nakagawa

Funding (7)

Illuminating the structure and function of CACNG5 and 7

2022-05-15 to 2024-05-14 | Grant
National Center for Advancing Translational Sciences (Rockville, US)
URL: https://app.dimensions.ai/details/grant/grant.12911136
GRANT_NUMBER: R03TR004196
Source: Self-asserted source
Terunaga Nakagawa via DimensionsWizard

Mechanism of functional modulation of glutamate receptors by their auxiliary subunits

2021-12-15 to 2025-11-30 | Grant
National Institute of Mental Health (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.10003281
GRANT_NUMBER: R01MH123474
Source: Self-asserted source
Terunaga Nakagawa via DimensionsWizard

Thermo Scientific Glacios cryo-TEM

2021-05-15 to 2022-05-14 | Grant
Office of the Director (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.9703945
GRANT_NUMBER: S10OD030292
Source: Self-asserted source
Terunaga Nakagawa via DimensionsWizard

Mechanism of functional modulation of glutamate receptors by their auxiliary subunits

2020-07-01 to 2022-06-30 | Grant
National Institute of Mental Health (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.9293324
GRANT_NUMBER: R56MH123474
Source: Self-asserted source
Terunaga Nakagawa via DimensionsWizard

Identifying molecules that modulate auxiliary factors of AMPA receptors

2014-08-01 to 2016-07-31 | Grant
National Institute of Mental Health (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.3804486
GRANT_NUMBER: R21MH102546
Source: Self-asserted source
Terunaga Nakagawa via DimensionsWizard

Isolation of ribonucleic acids that are attached to the neuronal membrane

2010-07-15 to 2015-04-30 | Grant
National Institute of Mental Health (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.2552282
GRANT_NUMBER: R01MH091664
Source: Self-asserted source
Terunaga Nakagawa via DimensionsWizard

Molecular Anatomy of Mature and Immature Glutamate Receptors

2010-07-10 to 2016-05-31 | Grant
Eunice Kennedy Shriver National Institute of Child Health and Human Development (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.2528081
GRANT_NUMBER: R01HD061543
Source: Self-asserted source
Terunaga Nakagawa via DimensionsWizard

Works (46)

GSG1L-containing AMPA receptor complexes are defined by their spatiotemporal expression, native interactome and allosteric sites.

Nature communications
2023-10-26 | Journal article
DOI: 10.1038/s41467-023-42517-7
PMID: 37884493
PMC: PMC10603098
Contributors: Amanda M Perozzo; Jochen Schwenk; Kamalova A; Nakagawa T; Bernd Fakler; Derek Bowie
Source: Self-asserted source
Terunaga Nakagawa

CryoEM structure of a post-assembly MS-ring reveals plasticity in stoichiometry and conformation.

PloS one
2023-05-19 | Journal article
DOI: 10.1371/journal.pone.0285343
PMID: 37205674
PMC: PMC10198558
Contributors: Prashant K. Singh; Cecchini G; Nakagawa T; TM Iverson
Source: Self-asserted source
Terunaga Nakagawa

Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeutics.

Nature communications
2023-03-25 | Journal article
DOI: 10.1038/s41467-023-37259-5
PMID: 36966141
PMC: PMC10039940
Contributors: Zhang D; Lape R; Shaikh SA; Kohegyi BK; Jake F Watson; Cais O; Nakagawa T; Ingo Greger
Source: Self-asserted source
Terunaga Nakagawa

Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels.

Pharmacological reviews
2021-10-01 | Journal article
DOI: 10.1124/pharmrev.120.000131
PMID: 34753794
PMC: PMC8626789
Contributors: Hansen KB; Wollmuth LP; Derek Bowie; Furukawa H; Menniti FS; Sobolevsky AI; Swanson GT; Swanger SA; Greger IH; Nakagawa T et al.
Source: Self-asserted source
Terunaga Nakagawa

AMPA receptor auxiliary subunit GSG1L suppresses short-term facilitation in corticothalamic synapses and determines seizure susceptibility.

Cell reports
2021-02-01 | Journal article
DOI: 10.1016/j.celrep.2021.108732
PMID: 33596427
PMC: PMC7982905
Contributors: Kamalova A; Futai K; Delpire E; Nakagawa T
Source: Self-asserted source
Terunaga Nakagawa

AMPA Receptor Auxiliary Subunit GSG1L Suppresses Short-Term Facilitation in Corticothalamic Synapses and Determines Seizure Susceptibility.

Cell reports
2020-07-01 | Journal article
DOI: 10.1016/j.celrep.2020.107921
PMID: 32697982
PMC: PMC7425083
Contributors: Kamalova A; Kensuke Futai; Delpire E; Nakagawa T
Source: Self-asserted source
Terunaga Nakagawa

AMPA receptor structure and auxiliary subunits.

The Journal of physiology
2020-02-18 | Journal article | Author
DOI: 10.1113/jp278701
PMID: 32004381
PMC: PMC7392800
Contributors: Kamalova A; Terunaga Nakagawa
Source: Self-asserted source
Terunaga Nakagawa

Mammalian Retromer Is an Adaptable Scaffold for Cargo Sorting from Endosomes.

Structure (London, England : 1993)
2020-02-05 | Journal article
DOI: 10.1016/j.str.2020.01.009
PMID: 32027819
PMC: PMC7145723
Contributors: Amy Kendall; Xie B; Xu P; Jue Wang; Burcham R; Meredith Frazier; Elad Binshtein; Wei H; Graham TR; Nakagawa T et al.
Source: Self-asserted source
Terunaga Nakagawa

Neuronal L-Type Calcium Channel Signaling to the Nucleus Requires a Novel CaMKIIα-Shank3 Interaction.

The Journal of neuroscience : the official journal of the Society for Neuroscience
2020-02-04 | Journal article
DOI: 10.1523/jneurosci.0893-19.2020
PMID: 32019829
PMC: PMC7055140
Contributors: Tyler L. Perfitt; Xiaohan Wang; Dickerson MT; Jason Stephenson; Nakagawa T; David A Jacobson; Roger Colbran
Source: Self-asserted source
Terunaga Nakagawa

Cryo-EM structure of human type-3 inositol triphosphate receptor reveals the presence of a self-binding peptide that acts as an antagonist.

The Journal of biological chemistry
2020-01-08 | Journal article
DOI: 10.1074/jbc.ra119.011570
PMID: 31915246
PMC: PMC7008357
Contributors: Azumaya CM; Linton EA; Caitlin J. Risener; Nakagawa T; Karakas E
Source: Self-asserted source
Terunaga Nakagawa

Structures of the AMPA receptor in complex with its auxiliary subunit cornichon.

Science (New York, N.Y.)
2019-12-01 | Journal article | Author
DOI: 10.1126/science.aay2783
PMID: 31806817
Contributors: Terunaga Nakagawa
Source: Self-asserted source
Terunaga Nakagawa

Structure-function analyses of the ion channel TRPC3 reveal that its cytoplasmic domain allosterically modulates channel gating.

The Journal of biological chemistry
2018-08-23 | Journal article
DOI: 10.1074/jbc.ra118.005066
PMID: 30139744
PMC: PMC6187627
Contributors: Francisco J Sierra-Valdez; Azumaya CM; Romero LO; Nakagawa T; Julio F Cordero-Morales
Source: Self-asserted source
Terunaga Nakagawa

Cryo-EM structure of the cytoplasmic domain of murine transient receptor potential cation channel subfamily C member 6 (TRPC6).

The Journal of biological chemistry
2018-05-11 | Journal article
DOI: 10.1074/jbc.ra118.003183
PMID: 29752403
PMC: PMC6028952
Contributors: Azumaya CM; Francisco J Sierra-Valdez; Julio F Cordero-Morales; Nakagawa T
Source: Self-asserted source
Terunaga Nakagawa

Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology.

Cell reports
2017-11-01 | Journal article
DOI: 10.1016/j.celrep.2017.11.009
PMID: 29186695
PMC: PMC5726791
Contributors: Savas JN; Wang YZ; DeNardo LA; Martinez-Bartolome S; Daniel McClatchy; Hark TJ; Shanks NF; Cozzolino KA; Mathieu Lavallée-Adam; Smukowski SN et al.
Source: Self-asserted source
Terunaga Nakagawa

A novel mechanism for Ca<sup>2+</sup>/calmodulin-dependent protein kinase II targeting to L-type Ca<sup>2+</sup> channels that initiates long-range signaling to the nucleus.

The Journal of biological chemistry
2017-09-15 | Journal article | Author
DOI: 10.1074/jbc.m117.788331
PMID: 28916724
PMC: PMC5655510
Contributors: Xiaohan Wang; Marks CR; Tyler L. Perfitt; Terunaga Nakagawa; Amy Lee; David A Jacobson; Roger Colbran
Source: Self-asserted source
Terunaga Nakagawa

Engineering defined membrane-embedded elements of AMPA receptor induces opposing gating modulation by cornichon 3 and stargazin.

The Journal of physiology
2017-09-12 | Journal article | Author
DOI: 10.1113/jp274897
PMID: 28815591
Contributors: Natalie Hawken; Zaika EI; Terunaga Nakagawa
Source: Self-asserted source
Terunaga Nakagawa

Screening for AMPA receptor auxiliary subunit specific modulators.

PloS one
2017-03-30 | Journal article
DOI: 10.1371/journal.pone.0174742
PMID: 28358902
PMC: PMC5373622
Contributors: Azumaya CM; Days EL; Vinson PN; Stauffer S; Sulikowski G; Weaver CD; Nakagawa T
Source: Self-asserted source
Terunaga Nakagawa

A Novel Human <i>CAMK2A</i> Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors.

The Journal of neuroscience : the official journal of the Society for Neuroscience
2017-01-27 | Journal article
DOI: 10.1523/jneurosci.2068-16.2017
PMID: 28130356
PMC: PMC5338762
Contributors: Jason Stephenson; Xiaohan Wang; Tyler L. Perfitt; Parrish WP; Brian Shonesy; Marks CR; Mortlock DP; Nakagawa T; Sutcliffe, JS; Roger Colbran
Source: Self-asserted source
Terunaga Nakagawa

Structural basis for integration of GluD receptors within synaptic organizer complexes.

Science (New York, N.Y.)
2016-07-01 | Journal article
DOI: 10.1126/science.aae0104
PMID: 27418511
PMC: PMC5291321
Contributors: Jonathan Elegheert; Kakegawa W; Clay JE; Shanks NF; Ester Behiels; Matsuda K; Kohda K; Miura E; Maxim Rossmann; Mitakidis N et al.
Source: Self-asserted source
Terunaga Nakagawa

Structural basis for extracellular cis and trans RPTPσ signal competition in synaptogenesis.

Nature communications
2014-11-11 | Journal article
DOI: 10.1038/ncomms6209
PMID: 25385546
PMC: PMC4239663
Contributors: Coles CH; Mitakidis N; Zhang P; Jonathan Elegheert; Lu W; Stoker AW; Nakagawa T; Craig AM; Yvonne Jones; A. Radu Aricescu
Source: Self-asserted source
Terunaga Nakagawa

Molecular dissection of the interaction between the AMPA receptor and cornichon homolog-3.

The Journal of neuroscience : the official journal of the Society for Neuroscience
2014-09-01 | Journal article
DOI: 10.1523/jneurosci.0595-14.2014
PMID: 25186755
PMC: PMC4152608
Contributors: Shanks NF; Cais O; Maruo T; Jeffrey Savas; Zaika EI; Azumaya CM; Yates JR 3rd; Greger I; Nakagawa T
Source: Self-asserted source
Terunaga Nakagawa

Differences in AMPA and kainate receptor interactomes facilitate identification of AMPA receptor auxiliary subunit GSG1L.

Cell reports
2012-05-23 | Journal article
DOI: 10.1016/j.celrep.2012.05.004
PMID: 22813734
PMC: PMC3401968
Contributors: Shanks NF; Savas JN; Maruo T; Cais O; Hirao A; Oe S; Ghosh A; Noda Y; Greger IH; Yates JR 3rd et al.
Source: Self-asserted source
Terunaga Nakagawa

Separation of domain contacts is required for heterotetrameric assembly of functional NMDA receptors.

The Journal of neuroscience : the official journal of the Society for Neuroscience
2011-03-01 | Journal article
DOI: 10.1523/jneurosci.6041-10.2011
PMID: 21389213
PMC: PMC3063151
Contributors: Farina AN; Blain KY; Maruo T; Kwiatkowski W; Choe S; Nakagawa T
Source: Self-asserted source
Terunaga Nakagawa

Lentiviral transgenesis.

Methods in molecular biology (Clifton, N.J.)
2011-01-01 | Journal article
DOI: 10.1007/978-1-60761-974-1_8
PMID: 21080278
Contributors: Nakagawa T; Casper Hoogenraad
Source: Self-asserted source
Terunaga Nakagawa

The biochemistry, ultrastructure, and subunit assembly mechanism of AMPA receptors.

Molecular neurobiology
2010-11-16 | Journal article
DOI: 10.1007/s12035-010-8149-x
PMID: 21080238
PMC: PMC2992128
Contributors: Nakagawa T
Source: Self-asserted source
Terunaga Nakagawa

The macromolecular architecture of extracellular domain of alphaNRXN1: domain organization, flexibility, and insights into trans-synaptic disposition.

Structure (London, England : 1993)
2010-08-01 | Journal article
DOI: 10.1016/j.str.2010.06.005
PMID: 20696403
PMC: PMC2948785
Contributors: Comoletti D; Miller MT; 0000-0002-8718-7343; Wilson J; Borries Demeler; Taylor P; Jill Trewhella; Nakagawa T
Source: Self-asserted source
Terunaga Nakagawa

Contribution of the global subunit structure and stargazin on the maturation of AMPA receptors.

The Journal of neuroscience : the official journal of the Society for Neuroscience
2010-02-01 | Journal article
DOI: 10.1523/jneurosci.5146-09.2010
PMID: 20164357
PMC: PMC2842908
Contributors: Shanks NF; Maruo T; Farina AN; Ellisman MH; Nakagawa T
Source: Self-asserted source
Terunaga Nakagawa

Molecular architecture of botulinum neurotoxin E revealed by single particle electron microscopy.

The Journal of biological chemistry
2007-11-20 | Journal article
DOI: 10.1074/jbc.m707917200
PMID: 18032388
Contributors: Fischer A; Garcia-Rodriguez C; Isin N. Geren; Lou J; Marks JD; Nakagawa T; Montal M
Source: Self-asserted source
Terunaga Nakagawa

Relative and absolute quantification of postsynaptic density proteome isolated from rat forebrain and cerebellum.

Molecular & cellular proteomics : MCP
2006-02-28 | Journal article
DOI: 10.1074/mcp.d500009-mcp200
PMID: 16507876
Contributors: Cheng D; Casper Hoogenraad; Rush J; Ramm E; Max A. Schlager; Duc Duong; Xu P; Wijayawardana SR; Hanfelt J; Nakagawa T et al.
Source: Self-asserted source
Terunaga Nakagawa

Three-dimensional structure of an AMPA receptor without associated stargazin/TARP proteins.

Biological chemistry
2006-02-01 | Journal article
DOI: 10.1515/bc.2006.024
PMID: 16497150
Contributors: Nakagawa T; Yifan Cheng; Morgan Sheng; Thomas Walz
Source: Self-asserted source
Terunaga Nakagawa

Generation of lentiviral transgenic rats expressing glutamate receptor interacting protein 1 (GRIP1) in brain, spinal cord and testis.

Journal of neuroscience methods
2005-09-12 | Journal article
DOI: 10.1016/j.jneumeth.2005.08.001
PMID: 16157387
Contributors: Nakagawa T; Mónica I. Feliú-Mójer; Wulf P; Lois C; Morgan Sheng; Casper Hoogenraad
Source: Self-asserted source
Terunaga Nakagawa

Mass of the postsynaptic density and enumeration of three key molecules.

Proceedings of the National Academy of Sciences of the United States of America
2005-08-01 | Journal article
DOI: 10.1073/pnas.0505359102
PMID: 16061821
PMC: PMC1182136
Contributors: Chen X; Vinade L; Richard D. Leapman; Jennifer D. Petersen; Nakagawa T; Phillips TM; Sheng M; Reese TS
Source: Self-asserted source
Terunaga Nakagawa

Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience
2005-03-01 | Journal article
DOI: 10.1523/jneurosci.0085-05.2005
PMID: 15788767
PMC: PMC6725094
Contributors: Keizo Takao; Kenichi Okamoto; Nakagawa T; Neve RL; Takeharu Nagai; Miyawaki A; Hashikawa T; Kobayashi S; Yasunori Hayashi
Source: Self-asserted source
Terunaga Nakagawa

Structure and different conformational states of native AMPA receptor complexes.

Nature
2005-02-01 | Journal article
DOI: 10.1038/nature03328
PMID: 15690046
Contributors: Nakagawa T; Yifan Cheng; Ramm E; Morgan Sheng; Thomas Walz
Source: Self-asserted source
Terunaga Nakagawa

Quaternary structure, protein dynamics, and synaptic function of SAP97 controlled by L27 domain interactions.

Neuron
2004-10-01 | Journal article
DOI: 10.1016/j.neuron.2004.10.012
PMID: 15504326
Contributors: Nakagawa T; Futai K; Lashuel HA; Lo I; Kenichi Okamoto; Thomas Walz; Yasunori Hayashi; Morgan Sheng
Source: Self-asserted source
Terunaga Nakagawa

The dynamic turnover and functional roles of alpha-actinin in dendritic spines.

Neuropharmacology
2004-10-01 | Journal article
DOI: 10.1016/j.neuropharm.2004.07.022
PMID: 15458845
Contributors: Nakagawa T; Engler JA; Morgan Sheng
Source: Self-asserted source
Terunaga Nakagawa

Actin/alpha-actinin-dependent transport of AMPA receptors in dendritic spines: role of the PDZ-LIM protein RIL.

The Journal of neuroscience : the official journal of the Society for Neuroscience
2004-09-01 | Journal article
DOI: 10.1523/jneurosci.2100-04.2004
PMID: 15456832
PMC: PMC6729893
Contributors: Schulz TW; Nakagawa T; Pawel Licznerski; Pawlak V; Alexander Kolleker; Rozov A; Kim J; Dittgen T; Köhr G; Morgan Sheng et al.
Source: Self-asserted source
Terunaga Nakagawa

Induction of dendritic spines by an extracellular domain of AMPA receptor subunit GluR2.

Nature
2003-08-01 | Journal article
DOI: 10.1038/nature01781
PMID: 12904794
Contributors: Passafaro M; Nakagawa T; Carlo Sala; Morgan Sheng
Source: Self-asserted source
Terunaga Nakagawa

Neurobiology: glutamate receptors on the move.

Nature
2002-06-01 | Journal article
DOI: 10.1038/417601a
PMID: 12050645
Contributors: Morgan Sheng; Nakagawa T
Source: Self-asserted source
Terunaga Nakagawa

Molecular motor KIF1C is not essential for mouse survival and motor-dependent retrograde Golgi apparatus-to-endoplasmic reticulum transport.

Molecular and cellular biology
2002-02-01 | Journal article
DOI: 10.1128/mcb.22.3.866-873.2002
PMID: 11784862
PMC: PMC133549
Contributors: Nakajima K; Takei Y; Yosuke Tanaka; Nakagawa T; Takao Nakata; Noda Y; Setou M; Hirokawa N
Source: Self-asserted source
Terunaga Nakagawa

Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta.

Cell
2001-06-01 | Journal article
DOI: 10.1016/s0092-8674(01)00363-4
PMID: 11389829
Contributors: Zhao C; Takita J; Yosuke Tanaka; Setou M; Nakagawa T; Takeda S; Yang HW; Sumio Terada; Nakata T; Takei Y et al.
Source: Self-asserted source
Terunaga Nakagawa

Neurobiology. A stargazer foretells the way to the synapse.

Science (New York, N.Y.)
2000-12-01 | Journal article
PMID: 11188726
Contributors: Nakagawa T; Sheng M
Source: Self-asserted source
Terunaga Nakagawa

A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex.

Cell
2000-11-01 | Journal article
DOI: 10.1016/s0092-8674(00)00161-6
PMID: 11106728
Contributors: Nakagawa T; Setou M; Seog D; Ogasawara K; Dohmae N; Takio K; Hirokawa N
Source: Self-asserted source
Terunaga Nakagawa

Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport.

Science (New York, N.Y.)
2000-06-01 | Journal article
DOI: 10.1126/science.288.5472.1796
PMID: 10846156
Contributors: Setou M; Nakagawa T; Seog DH; Hirokawa N
Source: Self-asserted source
Terunaga Nakagawa

Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.

Proceedings of the National Academy of Sciences of the United States of America
1997-09-01 | Journal article
DOI: 10.1073/pnas.94.18.9654
PMID: 9275178
PMC: PMC23244
Contributors: Nakagawa T; Yosuke Tanaka; Matsuoka E; Kondo S; Yasushi Okada; Noda Y; Yoshimitsu Kanai; Hirokawa N
Source: Self-asserted source
Terunaga Nakagawa

Two distinct functions of the carboxyl-terminal tail domain of NF-M upon neurofilament assembly: cross-bridge formation and longitudinal elongation of filaments.

The Journal of cell biology
1995-04-01 | Journal article
DOI: 10.1083/jcb.129.2.411
PMID: 7721944
PMC: PMC2199923
Contributors: Nakagawa T; Chen J; Zhang Z; Yoshimitsu Kanai; Hirokawa N
Source: Self-asserted source
Terunaga Nakagawa
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