Personal information

Activities

Employment (6)

Evotec France SAS: Toulouse, FR

2018-04-03 to present | Principal Scientist, Team Leader, Computational Drug Design (Molecular Architects)
Employment
Source: Self-asserted source
Martin Kotev

Nostrum Biodiscovery: Barcelona, ES

2016-09-01 to 2018-04-02 | Senior Project Manager, Computational Drug Design
Employment
Source: Self-asserted source
Martin Kotev

Institute for Research in Biomedicine: Barcelona, ES

2014-08-31 to 2016-08-31 | Senior Computational Chemist, Computational Drug Design (Molecular modelling and bioinformatics)
Employment
Source: Self-asserted source
Martin Kotev

Barcelona Supercomputing Center: Barcelona, ES

2011-01-09 to 2016-08-31 | Senior Computational Chemist, Computational Drug Design (part-time) (Electronic And Atomic Protein Modelling)
Employment
Source: Self-asserted source
Martin Kotev

Institute for Research in Biomedicine: Barcelona, ES

2011-01-09 to 2014-08-31 | Senior Computational Chemist, Computational Drug Design (Design, synthesis and structure of peptides and proteins)
Employment
Source: Self-asserted source
Martin Kotev

Bulgarian Academy of Sciences: Sofia, BG

2008-01-01 to 2011-01-08 | Research Fellow and Assistant Professor in Computational Chemistry (Institute of Organic Chemistry with Center of Phytochemistry)
Employment
Source: Self-asserted source
Martin Kotev

Education and qualifications (3)

B'lgarska akademia na naukite: Sofia, BG

2004-01-01 to 2007-12-31 | PhD, Computational Chemistry, http://unicat.nalis.bg/Record/BAS.000106568 (Institute of Organic Chemistry with Centre of Phytochemistry)
Education
Source: Self-asserted source
Martin Kotev

Sofia University St. Kliment Ohridski: Sofia, BG

2002-11-01 to 2004-03-25 | Master, Medicinal Chemistry (Faculty of Chemistry and Pharmacy)
Education
Source: Self-asserted source
Martin Kotev

Sofia University St. Kliment Ohridski: Sofia, BG

1998-10-01 to 2002-07-01 | Bachelor, Organic Chemistry (Faculty of Chemistry and Pharmacy)
Education
Source: Self-asserted source
Martin Kotev

Works (19)

Identification of the atypical antipsychotic Asenapine as a direct survivin inhibitor with anticancer properties and sensitizing effects to conventional therapies

Biomedicine & Pharmacotherapy
2025-01 | Journal article
Contributors: Cristina Benítez-García; David Martínez-García; Martin Kotev; Marta Pérez-Hernández; Yvonne Westermaier; Lucía Díaz; Luis Korrodi-Gregório; Pere Fontova; Ana Aurora Torres; Ricardo Pérez-Tomás et al.
Source: check_circle
Crossref

Molecular Dynamics and Other HPC Simulations for Drug Discovery

2024 | Book chapter
Contributors: Martin Kotev; Constantino Diaz Gonzalez
Source: check_circle
Crossref

Fine tuning for success in structure-based virtual screening

Journal of Computer-Aided Molecular Design
2021-12 | Journal article
Contributors: Emilie Pihan; Martin Kotev; Obdulia Rabal; Claudia Beato; Constantino Diaz Gonzalez
Source: check_circle
Crossref

User-Friendly Quantum Mechanics: Applications for Drug Discovery

Methods in Molecular Biology
2020-02-04 | Book chapter
Source: Self-asserted source
Martin Kotev

Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA

mBio
2019-07-09 | Journal article
Source: Self-asserted source
Martin Kotev

Pushing the Limits of Computational Structure-Based Drug Design with a Cryo-EM Structure: the Ca+2 Channel α2δ-1 Subunit as a Test Case

Journal of Chemical Information and Modeling
2018-07-27 | Journal article
Source: Self-asserted source
Martin Kotev

Inhibition of Human Enhancer of Zeste Homolog 2 with Tambjamine Analogs

Journal of Chemical Information and Modeling
2017 | Journal article
EID:

2-s2.0-85028571831

Contributors: Kotev, M.; Manuel-Manresa, P.; Hernando, E.; Soto-Cerrato, V.; Orozco, M.; Quesada, R.; Pérez-Tomás, R.; Guallar, V.
Source: Self-asserted source
Martin Kotev via Scopus - Elsevier

Combating virulence of Gram-negative bacilli by OmpA inhibition

Scientific Reports
2017-10-31 | Journal article
Source: Self-asserted source
Martin Kotev

Active-Site-Directed Inhibitors of Prolyl Oligopeptidase Abolish Its Conformational Dynamics

ChemBioChem
2016 | Journal article
EID:

2-s2.0-84962653011

Contributors: López, A.; Herranz-Trillo, F.; Kotev, M.; Gairí, M.; Guallar, V.; Bernadó, P.; Millet, O.; Tarragó, T.; Giralt, E.
Source: Self-asserted source
Martin Kotev via Scopus - Elsevier

Challenges of docking in large, flexible and promiscuous binding sites

Bioorganic and Medicinal Chemistry
2016 | Journal article
EID:

2-s2.0-84988965328

Contributors: Kotev, M.; Soliva, R.; Orozco, M.
Source: Self-asserted source
Martin Kotev via Scopus - Elsevier

Combined Use of Oligopeptides, Fragment Libraries, and Natural Compounds: A Comprehensive Approach to Sample the Druggability of Vascular Endothelial Growth Factor

ChemMedChem
2016 | Journal article
EID:

2-s2.0-84948183762

Contributors: Bayó-Puxan, N.; Rodríguez-Mias, R.; Goldflam, M.; Kotev, M.; Ciudad, S.; Hipolito, C.J.; Varese, M.; Suga, H.; Campos-Olivas, R.; Barril, X. et al.
Source: Self-asserted source
Martin Kotev via Scopus - Elsevier

Unveiling prolyl oligopeptidase ligand migration by comprehensive computational techniques

Biophysical Journal
2015 | Journal article
EID:

2-s2.0-84920990497

Contributors: Kotev, M.; Lecina, D.; Tarragó, T.; Giralt, E.; Guallar, V.
Source: Self-asserted source
Martin Kotev via Scopus - Elsevier

Test of a protocol for a conformational search and structural studies of complexes of (R,R)-α,α′-bis(trifluoromethyl)-9,10-anthracenedimethanol with orto-, meta- and para-benzenedimethanols.

Journal of the Bulgarian Academy of Sciences
2010-06-15 | Journal article
Source: Self-asserted source
Martin Kotev

Molecular mechanics (MM3(π)) conformational analysis of molecules containing conjugated π-electron fragments: Leucomycin-V

Chirality
2008 | Journal article
EID:

2-s2.0-39749102276

Contributors: Kotev, M.I.; Ivanov, P.M.
Source: Self-asserted source
Martin Kotev via Scopus - Elsevier

Molecular mechanics (MM3(π)) conformational analysis of molecules containing conjugated π-electron fragments: A molecular tweezer

Source: Self-asserted source
Martin Kotev

Computational (MM, MD and MDMM) study of bidentate complexes of (R,R)- and meso-α,α′-bis(trifluoromethyl)-9,10-anthracenedimethanol with cis-1-amino-2-indanol

Journal of Molecular Structure
2007 | Journal article
EID:

2-s2.0-33846631409

Contributors: Kotev, M.I.; Ivanov, P.M.; Virgili, A.; Estivill, C.
Source: Self-asserted source
Martin Kotev via Scopus - Elsevier

Conformational Search and Molecular Recognition with Molecular Mechanics: Macrocycles and Complexes of Chiral Derivatizing Agents

Bulgarian Academy of Sciences, Doctoral Thesis
2007-12-07 | Dissertation or Thesis
Source: Self-asserted source
Martin Kotev

Molecular mechanics (CONFLEX/MM3) search/minimization study of the conformations of ornoside and escuside

Journal of Molecular Structure
2005 | Journal article
EID:

2-s2.0-19444368249

Contributors: Kotev, M.I.; Goto, H.; Ivanov, P.M.
Source: Self-asserted source
Martin Kotev via Scopus - Elsevier

The bidentate complexes of (R,R)- and meso-α,α′- bis(trifluoromethyl)-9,10-anthracenedimethanol with cis-1-amino-2-indanol

Tetrahedron Asymmetry
2005 | Journal article
EID:

2-s2.0-24944465682

Contributors: Estivill, C.; Pomares, M.; Kotev, M.; Ivanov, P.; Virgili, A.
Source: Self-asserted source
Martin Kotev via Scopus - Elsevier