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Scopus Author ID: 6603458417
ResearcherID: D-9783-2012

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Employment (1)

Shiraz University of Medical Sciences: Shiraz, Fars, IR

1989-01-02 to present | Professor (Pharmacology and Toxicology, Faculty of Pharmacy)
Employment
Source: Self-asserted source
Hossein Niknahad

Education and qualifications (1)

University of Toronto: Toronto, ON, CA

1991-09-15 to 1995-12-24 | Ph.D. (Pharmacy)
Education
Source: Self-asserted source
Hossein Niknahad

Works (50 of 70)

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Page 1 of 2

Low‐dose ketamine improves animals' locomotor activity and decreases brain oxidative stress and inflammation in ammonia‐induced neurotoxicity

Journal of Biochemical and Molecular Toxicology
2023-11 | Journal article
DOI: 10.1002/jbt.23468
Contributors: Mohammad Mehdi Ommati; Ali Mobasheri; Hossein Niknahad; Mohammad Rezaei; Sepideh Alidaee; Abdollah Arjmand; Sahra Mazloomi; Narges Abdoli; Issa Sadeghian; Samira Sabouri et al.
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Crossref

Sildenafil Blunts Lung Inflammation and Oxidative Stress in a Rat Model of Cholestasis

Pharmaceutical Sciences
2023-02-20 | Journal article
DOI: 10.34172/PS.2022.38
Contributors: Mohammad Mehdi Ommati; Narges Abdoli; Meisam Firoozi; Alireza Akhlagh; Sahra Mazloomi; Khadijeh Mousavi; Hossein Niknahad; Reza Heidari
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Crossref

Betaine alleviates cholestasis-associated renal injury by mitigating oxidative stress and enhancing mitochondrial function

Biologia
2021-01-17 | Journal article
DOI: 10.2478/s11756-020-00576-x
Contributors: Mohammad Mehdi Ommati; Omid Farshad; Negar Azarpira; Marzieh Shafaghat; Hossein Niknahad; Reza Heidari
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Crossref

Boldine Supplementation Regulates Mitochondrial Function and Oxidative Stress in a Rat Model of Hepatotoxicity

Pharmaceutical Sciences
2019-03-18 | Journal article
DOI: 10.15171/PS.2019.1
Contributors: Reza Heidari; Mohammad Reza Arabnezhad; Mohammad Mehdi Ommati; Negar Azarpira; Elham Ghodsimanesh; Hossein Niknahad
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Crossref

Mitochondrial dysfunction as a mechanism involved in the pathogenesis of cirrhosis-associated cholemic nephropathy

Biomedicine & Pharmacotherapy
2019-01 | Journal article
DOI: 10.1016/j.biopha.2018.10.104
Contributors: Reza Heidari; Leila Mandegani; Vahid Ghanbarinejad; Asma Siavashpour; Mohammad Mehdi Ommati; Negar Azarpira; Asma Najibi; Hossein Niknahad
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Crossref

Betaine treatment protects liver through regulating mitochondrial function and counteracting oxidative stress in acute and chronic animal models of hepatic injury

Biomedicine and Pharmacotherapy
2018 | Journal article
DOI: 10.1016/j.biopha.2018.04.010
EID:

2-s2.0-85045040706
Contributors: Heidari, R.; Niknahad, H.; Sadeghi, A.; Mohammadi, H.; Ghanbarinejad, V.; Ommati, M.M.; Hosseini, A.; Azarpira, N.; Khodaei, F.; Farshad, O. et al.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Co-exposure to an Aryl Hydrocarbon Receptor Endogenous Ligand, 6-Formylindolo[3,2-b]carbazole (FICZ), and Cadmium Induces Cardiovascular Developmental Abnormalities in Mice

Biological Trace Element Research
2018 | Journal article
DOI: 10.1007/s12011-018-1391-1
EID:

2-s2.0-85047666756
Contributors: Omidi, M.; Niknahad, H.; Noorafshan, A.; Fardid, R.; Nadimi, E.; Naderi, S.; Bakhtari, A.; Mohammadi-Bardbori, A.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Diazinon interrupts ovarian steroidogenic acute regulatory (StAR) gene transcription in gonadotropin-stimulated rat model

Iranian Journal of Pharmaceutical Research
2018 | Journal article
EID:

2-s2.0-85045044333
Contributors: Siavashpour, A.; Ghasemi, Y.; Khalvati, B.; Jeivad, F.; Azarpira, N.; Niknahad, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Dithiothreitol supplementation mitigates hepatic and renal injury in bile duct ligated mice: Potential application in the treatment of cholestasis-associated complications

Biomedicine and Pharmacotherapy
2018 | Journal article
DOI: 10.1016/j.biopha.2018.01.018
EID:

2-s2.0-85039908297
Contributors: Heidari, R.; Ghanbarinejad, V.; Mohammadi, H.; Ahmadi, A.; Esfandiari, A.; Azarpira, N.; Niknahad, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Exacerbated liver injury of antithyroid drugs in endotoxin-treated mice

Drug and Chemical Toxicology
2018 | Journal article
DOI: 10.1080/01480545.2018.1459668
EID:

2-s2.0-85046396051
Contributors: Heidari, R.; Ahmadi, F.; Rahimi, H.R.; Azarpira, N.; Hosseinzadeh, M.; Najibi, A.; Niknahad, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier
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Mechanism of valproic acid-induced Fanconi syndrome involves mitochondrial dysfunction and oxidative stress in rat kidney

Nephrology
2018 | Journal article
DOI: 10.1111/nep.13012
EID:

2-s2.0-85024364598
Contributors: Heidari, R.; Jafari, F.; Khodaei, F.; Shirazi Yeganeh, B.; Niknahad, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Mitochondria protection as a mechanism underlying the hepatoprotective effects of glycine in cholestatic mice

Biomedicine and Pharmacotherapy
2018 | Journal article
DOI: 10.1016/j.biopha.2017.10.166
EID:

2-s2.0-85033397303
Contributors: Heidari, R.; Ghanbarinejad, V.; Mohammadi, H.; Ahmadi, A.; Ommati, M.M.; Abdoli, N.; Aghaei, F.; Esfandiari, A.; Azarpira, N.; Niknahad, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Mitochondrial dysfunction and oxidative stress are involved in the mechanism of methotrexate-induced renal injury and electrolytes imbalance

Biomedicine and Pharmacotherapy
2018 | Journal article
DOI: 10.1016/j.biopha.2018.08.050
EID:

2-s2.0-85051768765
Contributors: Heidari, R.; Ahmadi, A.; Mohammadi, H.; Ommati, M.M.; Azarpira, N.; Niknahad, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Taurine supplementation abates cirrhosis-associated locomotor dysfunction

Clinical and Experimental Hepatology
2018 | Journal article
DOI: 10.5114/ceh.2018.75956
EID:

2-s2.0-85049752478
Contributors: Heidari, R.; Jamshidzadeh, A.; Ghanbarinejad, V.; Ommati, M.M.; Niknahad, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Ammonia-induced mitochondrial dysfunction and energy metabolism disturbances in isolated brain and liver mitochondria, and the effect of taurine administration: Relevance to hepatic encephalopathy treatment

Clinical and Experimental Hepatology
2017 | Journal article
DOI: 10.5114/ceh.2017.68833
EID:

2-s2.0-85030654615
Contributors: Niknahad, H.; Jamshidzadeh, A.; Heidari, R.; Zarei, M.; Ommati, M.M.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Carnosine protects brain mitochondria under hyperammonemic conditions: Relevance to hepatic encephalopathy treatment

PharmaNutrition
2017 | Journal article
DOI: 10.1016/j.phanu.2017.02.004
EID:

2-s2.0-85015637591
Contributors: Jamshidzadeh, A.; Niknahad, H.; Heidari, R.; Zarei, M.; Ommati, M.M.; Khodaei, F.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

N-acetylcysteine treatment blunts liver failure-associated impairment of locomotor activity

PharmaNutrition
2017 | Journal article
DOI: 10.1016/j.phanu.2017.10.003
EID:

2-s2.0-85032455691
Contributors: Ommati, M.M.; Jamshidzadeh, A.; Niknahad, H.; Mohammadi, H.; Sabouri, S.; Heidari, R.; Abdoli, N.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Propylthiouracil-induced mitochondrial dysfunction in liver and its relevance to drug-induced hepatotoxicity

Pharmaceutical Sciences
2017 | Journal article
DOI: 10.15171/PS.2017.15
EID:

2-s2.0-85023168305
Contributors: Jamshidzadeh, A.; Niknahad, H.; Heidari, R.; Azadbakht, M.; Khodaei, F.; Arabnezhad, M.R.; Farshad, O.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Sulfasalazine induces mitochondrial dysfunction and renal injury

Renal failure
2017 | Journal article
DOI: 10.1080/0886022X.2017.1399908
EID:

2-s2.0-85049619236
Contributors: Niknahad, H.; Heidari, R.; Mohammadzadeh, R.; Ommati, M.M.; Khodaei, F.; Azarpira, N.; Abdoli, N.; Zarei, M.; Asadi, B.; Rasti, M. et al.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Concurrent inflammation augments antimalarial drugs-induced liver injury in rats

Advanced Pharmaceutical Bulletin
2016 | Journal article
DOI: 10.15171/apb.2016.076
EID:

2-s2.0-85011371115
Contributors: Niknahad, H.; Heidari, R.; Firuzi, R.; Abazari, F.; Ramezani, M.; Azarpira, N.; Hosseinzadeh, M.; Najibi, A.; Saeedi, A.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Dithiothreitol (DTT) rescues mitochondria from nitrofurantoin-induced mitotoxicity in rat

Journal of Biochemical and Molecular Toxicology
2016 | Journal article
DOI: 10.1002/jbt.21825
EID:

2-s2.0-84994065666
Contributors: Omidi, M.; Niknahad, H.; Mohammadi-Bardbori, A.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Effect of thiol-reducing agents and antioxidants on sulfasalazine-induced hepatic injury in normotermic recirculating isolated perfused rat liver

Toxicological Research
2016 | Journal article
DOI: 10.5487/TR.2016.32.2.133
EID:

2-s2.0-84973575501
Contributors: Heidari, R.; Esmailie, N.; Azarpira, N.; Najibi, A.; Niknahad, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Evaluating the Role of Drug Metabolism and Reactive Intermediates in Trazodone-Induced Cytotoxicity toward Freshly-Isolated Rat Hepatocytes

Drug Research
2016 | Journal article
DOI: 10.1055/s-0042-109536
EID:

2-s2.0-84988353598
Contributors: Najibi, A.; Heidari, R.; Zarifi, J.; Jamshidzadeh, A.; Firoozabadi, N.; Niknahad, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Paradoxical effect of methimazole on liver mitochondria: In vitro and in vivo

Toxicology Letters
2016 | Journal article
DOI: 10.1016/j.toxlet.2016.08.003
EID:

2-s2.0-84982170300
Contributors: Niknahad, H.; Jamshidzadeh, A.; Heidari, R.; Hosseini, Z.; Mobini, K.; Khodaei, F.; Ommati, M.M.; Abdoli, N.; Keshavarz, N.; Bazyari, M. et al.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Prevention of phosphine-induced cytotoxicity by nutrients in HepG2 cells

Indian Journal of Medical Research
2016 | Journal article
DOI: 10.4103/0971-5916.200896
EID:

2-s2.0-85014061104
Contributors: Rashedinia, M.; Jamshidzadeh, A.; Mehrabadi, A.R.; Niknahad, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Sulfasalazine-induced renal and hepatic injury in rats and the protective role of taurine

BioImpacts
2016 | Journal article
DOI: 10.15171/bi.2016.01
EID:

2-s2.0-84977138520
Contributors: Heidari, R.; Rasti, M.; Yeganeh, B.S.; Niknahad, H.; Saeedi, A.; Najibi, A.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Sulfasalazine-induced renal injury in rats and the protective role of thiol-reductants

Renal Failure
2016 | Journal article
DOI: 10.3109/0886022X.2015.1096731
EID:

2-s2.0-84955640342
Contributors: Heidari, R.; Taheri, V.; Rahimi, H.R.; Shirazi Yeganeh, B.; Niknahad, H.; Najibi, A.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

The postulated hepatotoxic metabolite of methimazole causes mitochondrial dysfunction and energy metabolism disturbances in liver

Pharmaceutical Sciences
2016 | Journal article
DOI: 10.15171/PS.2016.35
EID:

2-s2.0-85012926071
Contributors: Niknahad, H.; Jamshidzadeh, A.; Heidari, R.; Abdoli, N.; Ommati, M.M.; Jafari, F.; Zarei, M.; Asadi, B.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

An overview on the proposed mechanisms of antithyroid drugs-induced liver injury

Advanced Pharmaceutical Bulletin
2015 | Journal article
DOI: 10.5681/apb.2015.001
EID:

2-s2.0-84924269975
Contributors: Heidari, R.; Niknahad, H.; Jamshidzadeh, A.; Eghbal, M.A.; Abdoli, N.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Carbonyl traps as potential protective agents against methimazole-induced liver injury

Journal of Biochemical and Molecular Toxicology
2015 | Journal article
DOI: 10.1002/jbt.21682
EID:

2-s2.0-84927776415
Contributors: Heidari, R.; Niknahad, H.; Jamshidzadeh, A.; Azarpira, N.; Bazyari, M.; Najibi, A.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Coenzyme Q10 remarkably improves the bio-energetic function of rat liver mitochondria treated with statins

European Journal of Pharmacology
2015 | Journal article
DOI: 10.1016/j.ejphar.2015.05.041
EID:

2-s2.0-84931273605
Contributors: Mohammadi-Bardbori, A.; Najibi, A.; Amirzadegan, N.; Gharibi, R.; Dashti, A.; Omidi, M.; Saeedi, A.; Ghafarian-Bahreman, A.; Niknahad, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Effect of taurine on chronic and acute liver injury: Focus on blood and brain ammonia

Toxicology Reports
2015 | Journal article
DOI: 10.1016/j.toxrep.2016.04.002
EID:

2-s2.0-84963543203
Contributors: Heidari, R.; Jamshidzadeh, A.; Niknahad, H.; Mardani, E.; Ommati, M.M.; Azarpira, N.; Khodaei, F.; Zarei, A.; Ayarzadeh, M.; Mousavi, S. et al.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Erratum to Carbonyl traps as potential protective agents against methimazole-induced liver injury, [Journal of Biochemical and Molecular Toxicology, 29(4), (2015), 173-181, Doi 10.1002/jbt.21682]

Journal of Biochemical and Molecular Toxicology
2015 | Journal article
DOI: 10.1002/jbt.21727
EID:

2-s2.0-84938562511
Contributors: Heidari, R.; Niknahad, H.; Jamshidzadeh, A.; Azarpira, N.; Bazyari, M.; Najibi, A.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Mitochondrial dysfunction as a mechanism for pioglitazone-induced injury toward HepG2 cell line

Pharmaceutical Sciences
2015 | Journal article
DOI: 10.5681/PS.2015.007
EID:

2-s2.0-84927605291
Contributors: Niknahad, H.; Heidari, R.; Alzuhairi, A.M.; Najibi, A.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Study of the effects of ATP suppliers and thiol reductants on toxicity of pioglitazone in isolated rat liver mitochondria

Iranian Journal of Pharmaceutical Research
2015 | Journal article
EID:

2-s2.0-84931022851
Contributors: Mehrabadi, A.R.; Jamshidzadeh, A.; Rashedinia, M.; Niknahad, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Sulfasalazine-induced hepatic injury in an ex vivo model of isolated perfused rat liver and the protective role of taurine

Pharmaceutical Sciences
2015 | Journal article
DOI: 10.15171/PS.2015.39
EID:

2-s2.0-84954507562
Contributors: Heidari, R.; Sadeghi, N.; Azarpira, N.; Niknahad, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

The effect of acute aripiprazole treatment on chemically and electrically induced seizures in mice: The role of nitric oxide

Epilepsy and Behavior
2015 | Journal article
DOI: 10.1016/j.yebeh.2015.05.018
EID:

2-s2.0-84930670245
Contributors: Shafaroodi, H.; Oveisi, S.; Hosseini, M.; Niknahad, H.; Moezi, L.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

The effects of sub-chronic treatment with aripiprazole on pentylenetetrazole-and electroshock-induced seizures in mice: The role of nitric oxide

Pharmacology
2015 | Journal article
DOI: 10.1159/000381550
EID:

2-s2.0-84930268372
Contributors: Moezi, L.; Hosseini, M.; Oveisi, S.; Niknahad, H.; Shafaroodi, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Factors affecting drug-induced liver injury: antithyroid drugs as instances

Clinical and molecular hepatology
2014 | Journal article
DOI: 10.3350/cmh.2014.20.3.237
EID:

2-s2.0-84991486774
Contributors: Heidari, R.; Niknahad, H.; Jamshidzadeh, A.; Abdoli, N.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

The role of alpha-2 adrenoceptors in the anticonvulsant effects of adenosine on pentylenetetrazole-induced seizure threshold in mice

Pharmacology Biochemistry and Behavior
2014 | Journal article
DOI: 10.1016/j.pbb.2014.09.008
EID:

2-s2.0-84907289310
Contributors: Moezi, L.; Mansoori, E.; Niknahad, H.; Shafaroodi, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Evaluating the effects of dithiothreitol and fructose on cell viability and function of cryopreserved primary rat hepatocytes and HepG2 cell line

Hepatitis Monthly
2013 | Journal article
DOI: 10.5812/hepatmon.7824
EID:

2-s2.0-84874052059
Contributors: Aghdai, M.H.; Jamshidzadeh, A.; Nematizadeh, M.; Behzadiannia, M.; Niknahad, H.; Amirghofran, Z.; Esfandiari, E.; Azarpira, N.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

The interaction of adenosine and morphine on pentylenetetrazoleinduced seizure threshold in mice

Neuropharmacology
2013 | Journal article
DOI: 10.1016/j.neuropharm.2013.04.017
EID:

2-s2.0-84884837656
Contributors: Moezi, L.; Akbarian, R.; Niknahad, H.; Shafaroodi, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Comparison of the low dose polyethylene glycol with lactulose and magnesium hydroxide in constipated children. A multicentric randomized clinical trial

Life Science Journal
2012 | Journal article
EID:

2-s2.0-84877044568
Contributors: Gheibi, S.; Hadi Imanieh, M.; Haghighat, M.; Niknahad, H.; Sadegh Sayyafan, M.; Moatamed, F.; Hussein Saneian, M.; Karami, H.; Esmaeili Dooki, M.R.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Hepatoprotective effect of pomegranate (Punica granatum) fruit juice and seed extracts against CCL<inf>4</inf>-induced toxicity

Iranian Journal of Pharmaceutical Sciences
2012 | Journal article
EID:

2-s2.0-84876207805
Contributors: Jamshidzadeh, A.; Abbasian, M.; Mehrabadi, A.R.; Niknahad, H.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Metabolism and cytotoxic mechanisms of nitroglycerin in isolated rat hepatocytes

Iranian Journal of Pharmaceutical Sciences
2012 | Journal article
EID:

2-s2.0-84883169059
Contributors: Niknahad, H.; O'Brien, P.J.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Protective effects of a magnesium magnetic isotope (Mg<sup>25</sup>)-exchanging nanoparticle (<sup>25</sup>MgPMC<inf>16</inf>) on mitochondrial functional disorders in esmolol-induced cardiac arrest in rats

Autonomic and Autacoid Pharmacology
2012 | Journal article
DOI: 10.1111/j.1474-8673.2011.00464.x
EID:

2-s2.0-84858752947
Contributors: Adeli, S.; Zarrindast, M.R.; Niknahad, H.; Sarkar, S.; Bidgoli, S.A.; Korani, M.; Ghasemzadeh, P.; Rezayat, S.M.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Effect of helper lipids on stability and transfection activity of lyophilized lipoplex formulations of antisense and DOTAP nanoliposomes

Iranian Journal of Pharmaceutical Sciences
2011 | Journal article
EID:

2-s2.0-84857512988
Contributors: Tamaddon, A.M.; Niknahad, H.; Nikravesh, M.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Protective effect of captopril against doxorubicin-induced Oxidative stress in isolated rat liver mitochondria

Iranian Journal of Pharmaceutical Sciences
2010 | Journal article
EID:

2-s2.0-79956349050
Contributors: Niknahad, H.; Taghdiri, A.; Mohammadi-Bardbori, A.; Mehrabadi, A.R.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Effect of dithiotheritol on viability of cryopreserved rat hepatocytes

Daru
2009 | Journal article
EID:

2-s2.0-70350341676
Contributors: Jamshidzadeh, A.; Hosseinaghdaie, M.; Niknahad, H.; Nematizadeh, M.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier

Effect of lycopene on cyclophosphamide-induced hemorrhagic cystitis in rats

Iranian Journal of Medical Sciences
2009 | Journal article
EID:

2-s2.0-65749115849
Contributors: Jamshidzadeh, A.; Niknahad, H.; Azarpira, N.; Mohammadi-Bardbori, A.; Delnavaz, M.
Source: Self-asserted source
Hossein Niknahad via Scopus - Elsevier
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Review activity for European journal of pharmacology. (1)
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