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Employment (1)

UCB Celltech: Slough, Berkshire, GB

2007-07 to present | Principle Scientist (Immunology Therapeutic Area)
Employment
Source: Self-asserted source
Tania Rowley

Education and qualifications (1)

University of Southampton: Southampton, Hampshire, GB

2000-09-01 to 2004-05-01 | PhD in Immunology (Cancer Sciences)
Education
Source: Self-asserted source
Tania Rowley

Works (14)

On-target IgG hexamerisation driven by a C-terminal IgM tail-piece fusion variant confers augmented complement activation.

Communications biology
2021-09 | Journal article
DOI: 10.1038/s42003-021-02513-3
PMID: 34475514
PMC: PMC8413284
Contributors: Sopp JM; Peters SJ; Rowley TF; Oldham RJ; James S; Mockridge I; French RR; Turner A; Beers SA; Humphreys DP et al.
Source: Self-asserted source
Tania Rowley via Europe PubMed Central

Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases.

Arthritis & rheumatology (Hoboken, N.J.)
2021-04 | Journal article
DOI: 10.1002/art.41610
PMID: 33497037
Contributors: Barturen G; Babaei S; Català-Moll F; Martínez-Bueno M; Makowska Z; Martorell-Marugán J; Carmona-Sáez P; Toro-Domínguez D; Carnero-Montoro E; Alarcón-Riquelme ME
Source: Self-asserted source
Tania Rowley via Europe PubMed Central

Impact of Human FcγR Gene Polymorphisms on IgG-Triggered Cytokine Release: Critical Importance of Cell Assay Format.

Frontiers in immunology
2019-03 | Journal article
DOI: 10.3389/fimmu.2019.00390
PMID: 30899264
PMC: PMC6417454
Contributors: Hussain K; Hargreaves CE; Rowley TF; Sopp JM; Latham KV; Bhatta P; Sherington J; Cutler RM; Humphreys DP; Glennie MJ et al.
Source: Self-asserted source
Tania Rowley via Europe PubMed Central

Engineered hexavalent Fc proteins with enhanced Fc-gamma receptor avidity provide insights into immune-complex interactions.

Communications biology
2018-09 | Journal article
DOI: 10.1038/s42003-018-0149-9
PMID: 30272022
PMC: PMC6138732
Contributors: Rowley TF; Peters SJ; Aylott M; Griffin R; Davies NL; Healy LJ; Cutler RM; Eddleston A; Pither TL; Sopp JM et al.
Source: Self-asserted source
Tania Rowley via Europe PubMed Central

Multivalent Fcγ-receptor engagement by a hexameric Fc-fusion protein triggers Fcγ-receptor internalisation and modulation of Fcγ-receptor functions.

Scientific reports
2017-12 | Journal article
DOI: 10.1038/s41598-017-17255-8
PMID: 29213127
PMC: PMC5719016
Contributors: Qureshi OS; Rowley TF; Junker F; Peters SJ; Crilly S; Compson J; Eddleston A; Björkelund H; Greenslade K; Parkinson M et al.
Source: Self-asserted source
Tania Rowley via Europe PubMed Central

CD27 costimulation contributes substantially to the expansion of functional memory CD8(+) T cells after peptide immunization.

European journal of immunology
2013-10 | Journal article
DOI: 10.1002/eji.201343579
PMID: 24002868
Contributors: Taraban VY; Rowley TF; Kerr JP; Willoughby JE; Johnson PM; Al-Shamkhani A; Buchan SL
Source: Self-asserted source
Tania Rowley via Europe PubMed Central

Triggering of TNFRSF25 promotes CD8⁺ T-cell responses and anti-tumor immunity.

European journal of immunology
2011-08 | Journal article
DOI: 10.1002/eji.201141477
PMID: 21688261
Contributors: Slebioda TJ; Rowley TF; Ferdinand JR; Willoughby JE; Buchan SL; Taraban VY; Al-Shamkhani A
Source: Self-asserted source
Tania Rowley via Europe PubMed Central

The Death Receptor 3-TNF-like protein 1A pathway drives adverse bone pathology in inflammatory arthritis.

The Journal of experimental medicine
2008-09 | Journal article
DOI: 10.1084/jem.20072378
PMID: 18824582
PMC: PMC2571920
Contributors: Bull MJ; Williams AS; Mecklenburgh Z; Calder CJ; Twohig JP; Elford C; Evans BA; Rowley TF; Slebioda TJ; Taraban VY et al.
Source: Self-asserted source
Tania Rowley via Europe PubMed Central

Eradication of lymphoma by CD8 T cells following anti-CD40 monoclonal antibody therapy is critically dependent on CD27 costimulation.

Blood
2007-02 | Journal article
DOI: 10.1182/blood-2006-11-057216
PMID: 17311995
Contributors: French RR; Taraban VY; Crowther GR; Rowley TF; Gray JC; Johnson PW; Tutt AL; Al-Shamkhani A; Glennie MJ
Source: Self-asserted source
Tania Rowley via Europe PubMed Central

Inhibition of p38 mitogen-activated protein kinase unmasks a CD30-triggered apoptotic pathway in anaplastic large cell lymphoma cells.

Molecular cancer therapeutics
2007-02 | Journal article
DOI: 10.1158/1535-7163.mct-06-0544
PMID: 17308066
Contributors: Krysov SV; Rowley TF; Al-Shamkhani A
Source: Self-asserted source
Tania Rowley via Europe PubMed Central

Requirement for CD70 in CD4+ Th cell-dependent and innate receptor-mediated CD8+ T cell priming.

Journal of immunology (Baltimore, Md. : 1950)
2006-09 | Journal article
DOI: 10.4049/jimmunol.177.5.2969
PMID: 16920932
Contributors: Taraban VY; Rowley TF; Tough DF; Al-Shamkhani A
Source: Self-asserted source
Tania Rowley via Europe PubMed Central

Cutting edge: a critical role for CD70 in CD8 T cell priming by CD40-licensed APCs.

Journal of immunology (Baltimore, Md. : 1950)
2004-12 | Journal article
DOI: 10.4049/jimmunol.173.11.6542
PMID: 15557144
Contributors: Taraban VY; Rowley TF; Al-Shamkhani A
Source: Self-asserted source
Tania Rowley via Europe PubMed Central

Stimulation by soluble CD70 promotes strong primary and secondary CD8+ cytotoxic T cell responses in vivo.

Journal of immunology (Baltimore, Md. : 1950)
2004-05 | Journal article
DOI: 10.4049/jimmunol.172.10.6039
PMID: 15128787
Contributors: Rowley TF; Al-Shamkhani A
Source: Self-asserted source
Tania Rowley via Europe PubMed Central

Expression and costimulatory effects of the TNF receptor superfamily members CD134 (OX40) and CD137 (4-1BB), and their role in the generation of anti-tumor immune responses.

European journal of immunology
2002-12 | Journal article
DOI: 10.1002/1521-4141(200212)32:12<3617::aid-immu3617>3.0.co;2-m
PMID: 12516549
Contributors: Taraban VY; Rowley TF; O'Brien L; Chan HT; Haswell LE; Green MH; Tutt AL; Glennie MJ; Al-Shamkhani A
Source: Self-asserted source
Tania Rowley via Europe PubMed Central
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