Personal information

Emails & domains

Verified email domains

Other IDs

Scopus Author ID: 57205696102

Keywords

MAPK, Cancer, Autophagy, Mitochondria, Senescence, Oxidative Stress

Activities

Collapse all

Education and qualifications (3)

University of Siena: Siena, IT

2018-10 to 2022-03 | PhD in Genetics, Oncology and Clinical Medicine (Biotecnologie Mediche)
Education
Source: Self-asserted source
Lorenzo Franci

University of Siena: Siena, IT

2015-11 to 2018-06 | Master of Science in Molecular and Cellular Biology (Scienze della vita)
Education
Source: Self-asserted source
Lorenzo Franci

University of Siena: Siena, IT

2011-10 to 2015-04 | Bachelor in Biology (Scienze della vita)
Education
Source: Self-asserted source
Lorenzo Franci

Works (14)

MAPK15 PROTECTS AGAINST THE DEVELOPMENT OF METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE

2024-12-23 | Preprint
DOI: 10.1101/2024.12.23.630083
Contributors: Giovanni Inzalaco; Sara Gargiulo; Denise Bonente; Lisa Gherardini; Lorenzo Franci; Nicla Lorito; Serena Del Turco; Danilo Tatoni; Tiziana Tamborrino; Eugenio Bertelli et al.
Source: check_circle
Crossref

MAPK15 controls cellular responses to oxidative stress by regulating NRF2 activity and expression of its downstream target genes

Redox Biology
2024-06 | Journal article
DOI: 10.1016/j.redox.2024.103131
Part of ISSN: 2213-2317
Contributors: Lorenzo Franci; Giulia Vallini; Franca Maria Bertolino; Vittoria Cicaloni; Giovanni Inzalaco; Mattia Cicogni; Laura Tinti; Laura Calabrese; Virginia Barone; Laura Salvini et al.
Source: Self-asserted source
Lorenzo Franci

NRF2 activation by cysteine as a survival mechanism for triple-negative breast cancer cells

Oncogene
2024-05-29 | Journal article
DOI: 10.1038/s41388-024-03025-0
Contributors: Laura Bottoni; Alberto Minetti; Giulia Realini; Elena Pio; Daniela Giustarini; Ranieri Rossi; Chiara Rocchio; Lorenzo Franci; Laura Salvini; Orazio Catona et al.
Source: check_circle
Crossref

Co-Expression of Podoplanin and CD44 in Proliferative Vitreoretinopathy Epiretinal Membranes

International Journal of Molecular Sciences
2023-06-04 | Journal article
DOI: 10.3390/ijms24119728
Contributors: Denise Bonente; Laura Bianchi; Rossana De Salvo; Claudio Nicoletti; Elena De Benedetto; Tommaso Bacci; Luca Bini; Giovanni Inzalaco; Lorenzo Franci; Mario Chiariello et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Loco-regional treatment with temozolomide-loaded thermogels prevents glioblastoma recurrences in orthotopic human xenograft models

Scientific Reports
2023-03-21 | Journal article | Author
DOI: 10.1038/s41598-023-31811-5
Part of ISSN: 2045-2322
Contributors: lisa gherardini; Veronica Vetri Buratti; Mirko Maturi; GIOVANNI INZALACO; ERICA LOCATELLI; Letizia Sambri; Sara Gargiulo; Virginia Barone; Denise Bonente; Eugenio Bertelli et al.
Source: Self-asserted source
Lorenzo Franci

MAPK15 controls mitochondrial fitness and contributes to prevent cellular senescence

Autophagy Reports
2022-12-31 | Journal article
DOI: 10.1080/27694127.2022.2113016
Contributors: Lorenzo Franci; Giovanni Inzalaco; Mario Chiariello
Source: check_circle
Crossref

MAPK15 protects from oxidative stress‐dependent cellular senescence by inducing the mitophagic process

Aging Cell
2022-07 | Journal article
DOI: 10.1111/acel.13620
Contributors: Lorenzo Franci; Alessandro Tubita; Franca Maria Bertolino; Alessandro Palma; Giuseppe Cannino; Carmine Settembre; Andrea Rasola; Elisabetta Rovida; Mario Chiariello
Source: check_circle
Crossref

Rab7a regulates vimentin phosphorylation through akt and pak

Cancers
2021 | Journal article
DOI: 10.3390/cancers13092220
EID:

2-s2.0-85105206553

Part of ISSN: 20726694
Contributors: Romano, R.; Calcagnile, M.; Margiotta, A.; Franci, L.; Chiariello, M.; Alifano, P.; Bucci, C.
Source: Self-asserted source
Lorenzo Franci via Scopus - Elsevier
grade
Preferred source (of 3)‎

Superior properties of N-acetylcysteine ethyl ester over n-acetyl cysteine to prevent retinal pigment epithelial cells oxidative damage

International Journal of Molecular Sciences
2021 | Journal article
DOI: 10.3390/ijms22020600
EID:

2-s2.0-85099158826

Part of ISSN: 14220067 16616596
Contributors: Tosi, G.M.; Giustarini, D.; Franci, L.; Minetti, A.; Imperatore, F.; Caldi, E.; Fiorenzani, P.; Aloisi, A.M.; Sparatore, A.; Rossi, R. et al.
Source: Self-asserted source
Lorenzo Franci via Scopus - Elsevier
grade
Preferred source (of 3)‎

MAPK15 Controls Hedgehog Signaling in Medulloblastoma Cells by Regulating Primary Ciliogenesis

Cancers
2021-09-29 | Journal article
DOI: 10.3390/cancers13194903
Part of ISSN: 2072-6694
Source: Self-asserted source
Lorenzo Franci
grade
Preferred source (of 2)‎

The FHP01 DDX3X Helicase Inhibitor Exerts Potent Anti-Tumor Activity In Vivo in Breast Cancer Pre-Clinical Models

Cancers
2021-09-27 | Journal article
DOI: 10.3390/cancers13194830
Part of ISSN: 2072-6694
Source: Self-asserted source
Lorenzo Franci
grade
Preferred source (of 2)‎

Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction

ACS Chemical Biology
2020 | Journal article
DOI: 10.1021/acschembio.0c00039
EID:

2-s2.0-85083620035

Part of ISSN: 15548937 15548929
Contributors: Iralde-Lorente, L.; Tassone, G.; Clementi, L.; Franci, L.; Munier, C.C.; Cau, Y.; Mori, M.; Chiariello, M.; Angelucci, A.; Perry, M.W.D. et al.
Source: Self-asserted source
Lorenzo Franci via Scopus - Elsevier
grade
Preferred source (of 2)‎

Chemically stable inhibitors of 14-3-3 protein–protein interactions derived from BV02

Journal of Enzyme Inhibition and Medicinal Chemistry
2019 | Journal article
DOI: 10.1080/14756366.2019.1574779
EID:

2-s2.0-85061125641

Part of ISSN: 14756374 14756366
Contributors: Iralde-Lorente, L.; Cau, Y.; Clementi, L.; Franci, L.; Tassone, G.; Valensin, D.; Mori, M.; Angelucci, A.; Chiariello, M.; Botta, M.
Source: Self-asserted source
Lorenzo Franci via Scopus - Elsevier
grade
Preferred source (of 2)‎

Small Molecules as Potential Inhibitors of the 14-3-3/c-Abl Interaction for the Treatment of CML

2019-08-07 | Conference paper
DOI: 10.3390/proceedings2019022017
Contributors: Leire Iralde-Lorente; Giusy Tassone; Ylenia Cau; Claire Munier; Lorenzo Franci; Cecilia Pozzi; Adriano Angelucci; Mario Chiariello; Matthew Perry; Stefano Mangani et al.
Source: check_circle
Crossref
How many people are using ORCID?