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medicinal chemistry, infectious diseases, organic chemistry
Belgium

Activities

Employment (3)

University of California, San Francisco: San Francisco, California, US

2023-03 to 2025-03 | Postdoctoral Fellow (Pharmaceutical Sciences)
Employment
Source: Self-asserted source
Gilles Degotte

Université Grenoble Alpes: Saint-Martin-d'Hères, FR

2022-03 to 2023-03 | Postdoctoral fellow (Department of Molecular Chemistry)
Employment
Source: Self-asserted source
Gilles Degotte

Fonds De La Recherche Scientifique - FNRS: Liège, BE

2017-10-01 to 2021-12-21 | PhD student (FRIA) (Laboratory of Pharmacognosy)
Employment
Source: Self-asserted source
Gilles Degotte

Education and qualifications (3)

University of Liège: Liège, Liège, BE

2017-10 to 2021-12 | PhD in Biomedical and Pharmaceutical Sciences
Education
Source: Self-asserted source
Gilles Degotte

University of Liège: Liège, Liège, BE

2015-09 to 2017-06 | Master in Biomedical and Pharmaceutical Sciences
Education
Source: Self-asserted source
Gilles Degotte

University of Liège: Liège, Liège, BE

2012-09 to 2015-06 | Bachelor in Biomedical and Pharmaceutical Sciences
Education
Source: Self-asserted source
Gilles Degotte

Professional activities (4)

Société de Chimie Thérapeutique: Paris, FR

2022-10 to present | Website Manager
Service
Source: Self-asserted source
Gilles Degotte

Young MedChem Forum SCT: Paris, FR

2022 to present | Community Manager (LinkedIn)
Service
Source: Self-asserted source
Gilles Degotte

University of Liège: Liège, BE

2017-10-01 to 2021-12-21 | PhD student (FRIA) (Laboratory of Pharmacognosy)
Service
Source: Self-asserted source
Gilles Degotte

University of Liège: Liège, BE

2017-10-01 to 2021-12-21 | PhD student (FRIA) (Laboratory of Medicinal chemistry)
Service
Source: Self-asserted source
Gilles Degotte

Funding (4)

Malagic

2019-10 to 2021-09 | Grant
Fonds De La Recherche Scientifique - FNRS (Bruxelles, BE)
Source: Self-asserted source
Gilles Degotte

Malagic

2019-01 to 2021-12 | Grant
Fonds Léon Fredericq (Liège, BE)
Source: Self-asserted source
Gilles Degotte

Malagic

2018-01 to 2020-12 | Grant
Fonds Léon Fredericq (Liège, BE)
Source: Self-asserted source
Gilles Degotte

Malagic

2017-10 to 2019-10 | Contract
Fonds De La Recherche Scientifique - FNRS (Brussels, BE)
Source: Self-asserted source
Gilles Degotte

Works (11)

Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus-MProinhibitors with potent in vivo efficacy

2025-01-18 | Preprint
Contributors: Tyler C. Detomasi; Gilles Degotte; Sijie Huang; Rahul K. Suryawanshi; Amy Diallo; Luca Lizzadro; Francisco J. Zaptero-Belinchón; Taha Y. Taha; Jiapeng Li; Alicia Richards et al.
Source: check_circle
Crossref

Synthesis and pharmacological evaluation of fluoro/chloro-substituted acetyl and benzoyl esters of quinine as antimalarial agents

Results in Chemistry
2024-01 | Journal article
Contributors: Jean-Gonfi Mvondo Mbala; Dani Thierry Mawete; Alain Nanikafuako Makiese; Prosper Lwanzo Kwiraviwe; Bibiche Kuyubuka Pangu; Eric Buini Nguimi; Richard Cimanga Kanyanga; Luc Pieters; Gilles Degotte; Michel Frederich et al.
Source: check_circle
Crossref

Dimeric polyphenols to pave the way for new antimalarial drugs

RSC Medicinal Chemistry
2023 | Journal article
Contributors: Gilles Degotte; Hélène Pendeville; Carla Di Chio; Roberta Ettari; Bernard Pirotte; Michel Frédérich; Pierre Francotte
Source: check_circle
Crossref

Are plants of the Strychnos genus still a potential source of antiplasmodial metabolites after more than two centuries of study?

Planta Medica
2023-11-16 | Journal article
Contributors: Oliver Bonnet; Mehdi Benddir; Pierre Champy; Gilles Degotte; Lucia Mamede; Pauline Desdemoustier; Michel Frederich; Allison Ledoux; Alembert Tiabou Tchinda; Luc Angenot
Source: check_circle
Dimensions

Targeting Myeloperoxidase Activity and Neutrophil ROS Production to Modulate Redox Process: Effect of Ellagic Acid and Analogues

Molecules
2023-06-02 | Journal article
Contributors: Gilles Degotte; Michel Frederich; Pierre Francotte; Thierry Franck; Thomas Colson; Didier Serteyn; Ange Mouithys-Mickalad
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Insights into Antimalarial Activity of N-Phenyl-Substituted Cinnamanilides

Molecules
2022-11-12 | Journal article
Contributors: Jiri Kos; Gilles Degotte; Dominika Pindjakova; Tomas Strharsky; Timotej Jankech; Tomas Gonec; Pierre Francotte; Michel Frederich; Josef Jampilek
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Potential of Caffeic Acid Derivatives as Antimalarial Leads

Letters in Drug Design & Discovery
2022-09 | Journal article
Contributors: Gilles Degotte; Bernard Pirotte; Michel Frédérich; Pierre Francotte
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Unveiling antiplasmodial alkaloids from a cumulative collection of Strychnos extracts by multi-informative molecular networks

Frontiers in Molecular Biosciences
2022-09-26 | Journal article
Part of ISSN: 2296-889X
Contributors: Gilles Degotte; Olivier Bonnet; Mehdi A. Beniddir; Pierre Champy; Gilles Degotte; Lúcia Mamede; Pauline Desdemoustier; Allison Ledoux; Alembert Tiabou Tchinda; Luc Angenot et al.
Source: Self-asserted source
Gilles Degotte
grade
Preferred source (of 2)‎

Polyhydroxybenzoic acid derivatives as potential new antimalarial agents

Archiv der Pharmazie
2021-11 | Journal article
Contributors: Gilles Degotte; Bernard Pirotte; Michel Frédérich; Pierre Francotte
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Overview of Natural Antiplasmodials from the Last Decade to Inspire Medicinal Chemistry

Current Medicinal Chemistry
2021-09-17 | Journal article
Contributors: Gilles Degotte; Bernard Pirotte; Pierre Francotte; Michel Frédérich
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

In-vitro and in-vivo antimalarial activity of caffeic acid and some of its derivatives

Journal of Pharmacy and Pharmacology
2018-09-06 | Journal article
Part of ISSN: 2042-7158
Part of ISSN: 0022-3573
Source: Self-asserted source
Gilles Degotte
grade
Preferred source (of 2)‎

Peer review (10 reviews for 3 publications/grants)

Review activity for RSC advances (7)
Review activity for RSC medicinal chemistry. (2)
Review activity for The Journal of Venomous Animals and Toxins including Tropical Diseases. (1)