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Scopus Author ID: 54403817200

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Employment (1)

Instituto de Investigaciones en Medicina Traslacional (IIMT) - CONICET: Pilar , Buenos Aires, AR

2019-02-01 to present
Employment
Source: Self-asserted source
Mario Rossi

Education and qualifications (3)

University of Buenos Aires: Buenos Aires, AR

2017-12 to present | Master Data Science
Education
Source: Self-asserted source
Mario Rossi

University of Rome Tor Vergata: Rome, Lazio, IT

1999-12 to 2003-05 | PhD.
Education
Source: Self-asserted source
Mario Rossi

University of Buenos Aires: Buenos Aires, AR

1992-03 to 1998-12 | Licenciado (eq. to MSc.)
Education
Source: Self-asserted source
Mario Rossi

Professional activities (1)

Sociedad Argentina de Investigación Bioquímica y Biología Molecular: Ciudad Autonoma de Buenos Aires, Ciudad de Buenos Aires, AR

Membership
Source: Self-asserted source
Mario Rossi

Funding (6)

Characterization of USP19 in the control of tumor cell migration and invasion

2020 to 2023 | Grant
: National Agency for Science and Technology Promotion (ANPCyT) (Ciudad Autonoma de Buenos Aires, Ciudad de Buenos Aires, AR)
GRANT_NUMBER:

PICT-2018-0368
Source: Self-asserted source
Mario Rossi

Role of the ubiquitination cascade in the control of cell tumor invasion and metastasis

2018 to 2021 | Grant
National Agency for Science and Technology Promotion (ANPCyT) (Ciudad Autonoma de Buenos Aires, Ciudad de Buenos Aires, AR)
Source: Self-asserted source
Mario Rossi

Inhibition of Autophagic Pathway as a Therapeutic Strategy in Cancer Treatment

2015 to 2018 | Grant
National Agency for Science and Technology Promotion (ANPCyT) (Ciudad Autonoma de Buenos Aires, Ciudad de Buenos Aires, AR)
GRANT_NUMBER:

PICT-2014-0458
Source: Self-asserted source
Mario Rossi

Identification of Ubiquitin Proteasome System genes that control tumor cell migration and invasion

2013 to 2016 | Grant
National Agency for Science and Technology Promotion (ANPCyT) (Ciudad Autonoma de Buenos Aires, Ciudad de Buenos Aires, AR)
GRANT_NUMBER:

PICT-2011-2783
Source: Self-asserted source
Mario Rossi

Mechanisms of Control of the UPS in the Regulation of DNA Replication

2013 to 2015 | Grant
: National Agency for Science and Technology Promotion (ANPCyT) (Ciudad Autonoma de Buenos Aires, Ciudad de Buenos Aires, AR)
GRANT_NUMBER:

PICT-2011-1231
Source: Self-asserted source
Mario Rossi

Role of the SCF/FBX011 ubiquitin ligase in the control of cell proliferation

2011-08-28 to 2014-07-31 | Grant
Fogarty International Center (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.2580428
GRANT_NUMBER: R03TW009040
Source: Self-asserted source
Mario Rossi via DimensionsWizard

Works (39)

SCFβTrCP-mediated degradation of SHARP1 in triple-negative breast cancer

Cell Death & Disease
2023-11-08 | Journal article
DOI: 10.1038/s41419-023-06253-6
Contributors: Juliana Haydeé Enriqué Steinberg; Fabiana Alejandra Rossi; Roberto Magliozzi; Laurensia Yuniati; Matteo Santucci; Mario Rossi; Daniele Guardavaccaro; Angela Lauriola
Source: check_circle
Crossref

Ubiquitination Is a Novel Post-Translational Modification of VMP1 in Autophagy of Human Tumor Cells

International Journal of Molecular Sciences
2023-08-19 | Journal article
DOI: 10.3390/ijms241612981
Contributors: Felipe J. Renna; Juliana H. Enriqué Steinberg; Claudio D. Gonzalez; Maria Manifava; Mariana S. Tadic; Tamara Orquera; Carolina V. Vecino; Alejandro Ropolo; Daniele Guardavaccaro; Mario Rossi et al.
Source: check_circle
Crossref
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Preferred source (of 2)‎

Ubiquitination is a novel post-translational modification of VMP1 in autophagy of human tumor cells

2023-02-13 | Preprint
DOI: 10.1101/2023.02.13.528037
Contributors: Felipe J. Renna; Juliana H. Enriqué Steinberg; Claudio D. Gonzalez; Maria Manifava; Mariana S. Tadic; Tamara Orquera; Carolina V. Vecino; Alejandro Ropolo; Daniele Guardavaccaro; Mario Rossi et al.
Source: check_circle
Crossref

Emerging Role of Ubiquitin-Specific Protease 19 in Oncogenesis and Cancer Development.

Frontiers in cell and developmental biology
2022-05-12 | Journal article
DOI: 10.3389/fcell.2022.889166
PMID: 35646888
PMC: PMC9133600
Contributors: Rossi FA; Rossi M
Source: Self-asserted source
Mario Rossi

The BA-BCS 2021: An Initial "Trial" for Integrating Basic Science and Medical Progress on Breast Cancer in a Latin-American Country.

Journal of mammary gland biology and neoplasia
2021-09-01 | Journal article
DOI: 10.1007/s10911-021-09501-7
PMID: 34642841
PMC: PMC8510571
Contributors: Kordon E; Lanari C; Mando P; Novaro V; Rossi M; Simian M
Source: Self-asserted source
Mario Rossi

HERC1 Regulates Breast Cancer Cells Migration and Invasion

Cancers
2021-03-15 | Journal article
DOI: 10.3390/cancers13061309
Contributors: Fabiana Alejandra Rossi; Ezequiel Hernán Calvo Roitberg; Juliana Haydeé Enriqué Steinberg; Molishree Umesh Joshi; Joaquín Maximiliano Espinosa; Mario Rossi
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

USP19 modulates cancer cell migration and invasion and acts as a novel prognostic marker in patients with early breast cancer.

Oncogenesis
2021-03-13 | Journal article
DOI: 10.1038/s41389-021-00318-x
PMID: 33714979
Source: Self-asserted source
Mario Rossi

HERC1 regulates breast cancer cells migration and invasion

2020-11-05 | Other
DOI: 10.1101/2020.11.05.369975
Contributors: Fabiana Alejandra Rossi; Ezequiel Hernán Calvo Roitberg; Juliana Haydeé Enriqué Steinberg; Molishree Joshi; Joaquín Maximiliano Espinosa; Mario Rossi
Source: check_circle
Crossref

Bioinformatic analysis of RHO family of GTPases identifies RAC1 pharmacological inhibition as a new therapeutic strategy for hepatocellular carcinoma.

Gut
2020-10-26 | Journal article
DOI: 10.1136/gutjnl-2020-321454
PMID: 33106353
Source: Self-asserted source
Mario Rossi

PKCα Modulates Epithelial-to-Mesenchymal Transition and Invasiveness of Breast Cancer Cells Through ZEB1.

Frontiers in oncology
2019-11-27 | Journal article
DOI: 10.3389/fonc.2019.01323
PMID: 31828042
PMC: PMC6890807
Source: Self-asserted source
Mario Rossi

The ULK1-FBXW5-SEC23B nexus controls autophagy.

eLife
2018-12-31 | Journal article
DOI: 10.7554/elife.42253
PMID: 30596474
PMC: PMC6351106
Source: Self-asserted source
Mario Rossi

Alternative Splicing of G9a Regulates Neuronal Differentiation

Cell Reports
2016 | Journal article
DOI: 10.1016/j.celrep.2016.02.063
EID:

2-s2.0-84961226010
Contributors: Fiszbein, A.; Giono, L.E.; Quaglino, A.; Berardino, B.G.; Sigaut, L.; von Bilderling, C.; Schor, I.E.; Steinberg, J.H.E.; Rossi, M.; Pietrasanta, L.I. et al.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

The NSL Chromatin-Modifying Complex Subunit KANSL2 Regulates Cancer Stem-like Properties in Glioblastoma That Contribute to Tumorigenesis.

Cancer research
2016-07-12 | Journal article
DOI: 10.1158/0008-5472.can-15-3159
PMID: 27406830
PMC: PMC5026635
Source: Self-asserted source
Mario Rossi

High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy

Cell Death and Disease
2014 | Journal article
DOI: 10.1038/cddis.2014.113
EID:

2-s2.0-84901048406
Contributors: Rossi, M.; Rotblat, B.; Ansell, K.; Amelio, I.; Caraglia, M.; Misso, G.; Bernassola, F.; Cavasotto, C.N.; Knight, R.A.; Ciechanover, A. et al.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration

Molecular Cell
2013 | Journal article
DOI: 10.1016/j.molcel.2013.02.003
EID:

2-s2.0-84875806981
Contributors: Abbas, T.; Mueller, A.C.; Shibata, E.; Keaton, M.; Rossi, M.; Dutta, A.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

FBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stress

Journal of Cell Biology
2013 | Journal article
DOI: 10.1083/jcb.201209002
Contributors: Jeong, Y.-T.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

Regulation of the CRL4Cdt2 Ubiquitin Ligase and Cell-Cycle Exit by the SCFFbxo11 Ubiquitin Ligase

Molecular Cell
2013 | Journal article
DOI: 10.1016/j.molcel.2013.02.004
Contributors: Rossi, M.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas

Nature
2012 | Journal article
DOI: 10.1038/nature10688
Contributors: Duan, S.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

Caspase cleavage of Itch in chronic lymphocytic leukemia cells

Biochemical and Biophysical Research Communications
2009 | Journal article
DOI: 10.1016/j.bbrc.2008.11.154
Contributors: Rossi, M.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

Desmethylclomipramine induces the accumulation of autophagy markers by blocking autophagic flux

Journal of Cell Science
2009 | Journal article
DOI: 10.1242/jcs.048181
Contributors: Rossi, M.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

Itch self-polyubiquitylation occurs through lysine-63 linkages

Biochemical Pharmacology
2008 | Journal article
DOI: 10.1016/j.bcp.2008.07.028
Contributors: Scialpi, F.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

Itch: a HECT-type E3 ligase regulating immunity, skin and cancer

2008 | Journal article
DOI: 10.1038/cdd.2008.60
Contributors: Melino, G.
Source: Self-asserted source
Mario Rossi via ResearcherID

Yes-Associated Protein (YAP) is a critical mediator of c-Jun-dependent apoptosis [3]

Cell Death and Differentiation
2008 | Journal article
DOI: 10.1038/sj.cdd.4402226
Contributors: Danovi, S.A.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

Generation of ΔTAp73 proteins by translation from a putative internal ribosome entry site

Annals of the New York Academy of Sciences
2007 | Journal article
DOI: 10.1196/annals.1397.035
Contributors: Sayan, A.E.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

Itch inhibition regulates chemosensitivity in vitro

Biochemical and Biophysical Research Communications
2007 | Journal article
DOI: 10.1016/j.bbrc.2007.06.104
Contributors: Hansen, T.M.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

Key role of DNP63 in epidermal fate of embryonic stem (ES) cells and ES-derived ectodermal cell line

2007 | Journal article
Contributors: Medawar, A.
Source: Self-asserted source
Mario Rossi via ResearcherID

The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch

Proceedings of the National Academy of Sciences of the United States of America
2007 | Journal article
DOI: 10.1073/pnas.0701773104
Contributors: Oberst, A.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

FLASH is required for histone transcription and S-phase progression

Proceedings of the National Academy of Sciences of the United States of America
2006 | Journal article
DOI: 10.1073/pnas.0604227103
Contributors: Barcaroli, D.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

The E3 ubiquitin ligase Itch controls the protein stability of p63

Proceedings of the National Academy of Sciences of the United States of America
2006 | Journal article
DOI: 10.1073/pnas.0603449103
Contributors: Rossi, M.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

Calpain cleavage regulates the protein stability of p73

Biochemical and Biophysical Research Communications
2005 | Journal article
DOI: 10.1016/j.bbrc.2005.05.188
Contributors: Munarriz, E.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

Regulation of the p73 protein stability and degradation

Biochemical and Biophysical Research Communications
2005 | Journal article
DOI: 10.1016/j.bbrc.2005.03.158
Contributors: Oberst, A.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

The ubiquitin-protein ligase Itch regulates p73 stability

EMBO Journal
2005 | Journal article
DOI: 10.1038/sj.emboj.7600444
Contributors: Rossi, M.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

Mechanism of induction of apoptosis by p73 and its relevance to neuroblastoma biology

Annals of the New York Academy of Sciences
2004 | Journal article
DOI: 10.1196/annals.1322.015
Contributors: Rossi, M.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

P73: In silico evidence for a putative third promoter region

Biochemical and Biophysical Research Communications
2004 | Journal article
DOI: 10.1016/j.bbrc.2003.12.014
Contributors: Sayan, A.E.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier
grade
Preferred source (of 2)‎

Probing Protein-tyrosine Phosphatase Substrate Specificity Using a Phosphotyrosine-containing Phage Library

Journal of Biological Chemistry
2004 | Journal article
DOI: 10.1074/jbc.M307617200
Contributors: Wälchli, S.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

Alternative bacteriophage display systems

Combinatorial Chemistry and High Throughput Screening
2001 | Journal article
EID: 2-s2.0-0035043610
Contributors: Castagnoli, L.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier
grade
Preferred source (of 2)‎

From p63 to p53 across p73

FEBS Letters
2001 | Journal article
DOI: 10.1016/S0014-5793(01)02119-6
Contributors: Strano, S.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

Physical Interaction with Yes-associated Protein Enhances p73 Transcriptional Activity

Journal of Biological Chemistry
2001 | Journal article
DOI: 10.1074/jbc.M010484200
Contributors: Strano, S.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

Physical and functional interaction between p53 mutants and different isoforms of p73

Journal of Biological Chemistry
2000 | Journal article
DOI: 10.1074/jbc.M003360200
Contributors: Strano, S.
Source: Self-asserted source
Mario Rossi via Scopus - Elsevier

Peer review (9 reviews for 1 publication/grant)

Review activity for Oncogenesis. (9)
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