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Scopus Author ID: 57188681430

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Employment (2)

Second Xiangya Hospital: Changsha, Hunan, CN

2021-04-30 to present (Urology)
Employment
Source: Self-asserted source
Xin Jin

Wuhan Union Hospital: Wuhan, Hubei, CN

2013-07-01 to 2021-04-29 (Pancreatic surgery)
Employment
Source: Self-asserted source
Xin Jin

Education and qualifications (1)

Huazhong University of Science and Technology: Wuhan, Hubei, CN

2005-09-01 to 2013-06-30 | PH.D. and M.D. (tongji medical college)
Education
Source: Self-asserted source
Xin Jin

Works (50 of 121)

Items per page:
Page 1 of 3

Data from ZDHHC2-mediated AGK palmitoylation activates AKT/mTOR signaling to reduce sunitinib sensitivity in renal cell carcinoma

2024-09-16 | Preprint
DOI: 10.1158/0008-5472.c.6678641.v3
Contributors: Yan Sun; Liang Zhu; Pian Liu; Huan Zhang; Feng Guo; Xin Jin
Source: check_circle
Crossref

Data from ZDHHC2-mediated AGK palmitoylation activates AKT/mTOR signaling to reduce sunitinib sensitivity in renal cell carcinoma

2024-09-16 | Preprint
DOI: 10.1158/0008-5472.c.6678641
Contributors: Yan Sun; Liang Zhu; Pian Liu; Huan Zhang; Feng Guo; Xin Jin
Source: check_circle
Crossref

Supplementary Data from ZDHHC2-mediated AGK palmitoylation activates AKT/mTOR signaling to reduce sunitinib sensitivity in renal cell carcinoma

2024-09-16 | Preprint
DOI: 10.1158/0008-5472.27027629
Contributors: Yan Sun; Liang Zhu; Pian Liu; Huan Zhang; Feng Guo; Xin Jin
Source: check_circle
Crossref

Supplementary Data from ZDHHC2-mediated AGK palmitoylation activates AKT/mTOR signaling to reduce sunitinib sensitivity in renal cell carcinoma

2024-09-16 | Preprint
DOI: 10.1158/0008-5472.27027629.v1
Contributors: Yan Sun; Liang Zhu; Pian Liu; Huan Zhang; Feng Guo; Xin Jin
Source: check_circle
Crossref

Data from PRKDC Induces Chemoresistance in Osteosarcoma by Recruiting GDE2 to Stabilize GNAS and Activate AKT

2024-09-04 | Preprint
DOI: 10.1158/0008-5472.c.7431548
Contributors: Wenchao Zhang; Wei Li; Chi Yin; Chengyao Feng; Binfeng Liu; Haodong Xu; Xin Jin; Chao Tu; Zhihong Li
Source: check_circle
Crossref

Data from PRKDC Induces Chemoresistance in Osteosarcoma by Recruiting GDE2 to Stabilize GNAS and Activate AKT

2024-09-04 | Preprint
DOI: 10.1158/0008-5472.c.7431548.v1
Contributors: Wenchao Zhang; Wei Li; Chi Yin; Chengyao Feng; Binfeng Liu; Haodong Xu; Xin Jin; Chao Tu; Zhihong Li
Source: check_circle
Crossref

PRKDC Induces Chemoresistance in Osteosarcoma by Recruiting GDE2 to Stabilize GNAS and Activate AKT

Cancer Research
2024-09-04 | Journal article
DOI: 10.1158/0008-5472.CAN-24-0163
Contributors: Wenchao Zhang; Wei Li; Chi Yin; Chengyao Feng; Binfeng Liu; Haodong Xu; Xin Jin; Chao Tu; Zhihong Li
Source: check_circle
Crossref

Supplementary Data from PRKDC Induces Chemoresistance in Osteosarcoma by Recruiting GDE2 to Stabilize GNAS and Activate AKT

2024-09-04 | Preprint
DOI: 10.1158/0008-5472.26934686.v1
Contributors: Wenchao Zhang; Wei Li; Chi Yin; Chengyao Feng; Binfeng Liu; Haodong Xu; Xin Jin; Chao Tu; Zhihong Li
Source: check_circle
Crossref

Supplementary Data from PRKDC Induces Chemoresistance in Osteosarcoma by Recruiting GDE2 to Stabilize GNAS and Activate AKT

2024-09-04 | Preprint
DOI: 10.1158/0008-5472.26934686
Contributors: Wenchao Zhang; Wei Li; Chi Yin; Chengyao Feng; Binfeng Liu; Haodong Xu; Xin Jin; Chao Tu; Zhihong Li
Source: check_circle
Crossref

Supplementary Figure from PRKDC Induces Chemoresistance in Osteosarcoma by Recruiting GDE2 to Stabilize GNAS and Activate AKT

2024-09-04 | Preprint
DOI: 10.1158/0008-5472.26934683
Contributors: Wenchao Zhang; Wei Li; Chi Yin; Chengyao Feng; Binfeng Liu; Haodong Xu; Xin Jin; Chao Tu; Zhihong Li
Source: check_circle
Crossref

Supplementary Figure from PRKDC Induces Chemoresistance in Osteosarcoma by Recruiting GDE2 to Stabilize GNAS and Activate AKT

2024-09-04 | Preprint
DOI: 10.1158/0008-5472.26934683.v1
Contributors: Wenchao Zhang; Wei Li; Chi Yin; Chengyao Feng; Binfeng Liu; Haodong Xu; Xin Jin; Chao Tu; Zhihong Li
Source: check_circle
Crossref

CDK4/6 Alters TBK1 Phosphorylation to Inhibit the STING Signaling Pathway in Prostate Cancer

Cancer Research
2024-08-15 | Journal article
DOI: 10.1158/0008-5472.CAN-23-3704
Contributors: Wei Li; Feng Guo; Ruijiang Zeng; Huaiyuan Liang; Yinhuai Wang; Wei Xiong; Heshui Wu; Chunguang Yang; Xin Jin
Source: check_circle
Crossref

Data from CDK4/6 Alters TBK1 Phosphorylation to Inhibit the STING Signaling Pathway in Prostate Cancer

2024-08-15 | Preprint
DOI: 10.1158/0008-5472.c.7403503
Contributors: Wei Li; Feng Guo; Ruijiang Zeng; Huaiyuan Liang; Yinhuai Wang; Wei Xiong; Heshui Wu; Chunguang Yang; Xin Jin
Source: check_circle
Crossref

Data from CDK4/6 Alters TBK1 Phosphorylation to Inhibit the STING Signaling Pathway in Prostate Cancer

2024-08-15 | Preprint
DOI: 10.1158/0008-5472.c.7403503.v1
Contributors: Wei Li; Feng Guo; Ruijiang Zeng; Huaiyuan Liang; Yinhuai Wang; Wei Xiong; Heshui Wu; Chunguang Yang; Xin Jin
Source: check_circle
Crossref

Supplementary Data from CDK4/6 Alters TBK1 Phosphorylation to Inhibit the STING Signaling Pathway in Prostate Cancer

2024-08-15 | Preprint
DOI: 10.1158/0008-5472.26711002
Contributors: Wei Li; Feng Guo; Ruijiang Zeng; Huaiyuan Liang; Yinhuai Wang; Wei Xiong; Heshui Wu; Chunguang Yang; Xin Jin
Source: check_circle
Crossref

Supplementary Data from CDK4/6 Alters TBK1 Phosphorylation to Inhibit the STING Signaling Pathway in Prostate Cancer

2024-08-15 | Preprint
DOI: 10.1158/0008-5472.26711002.v1
Contributors: Wei Li; Feng Guo; Ruijiang Zeng; Huaiyuan Liang; Yinhuai Wang; Wei Xiong; Heshui Wu; Chunguang Yang; Xin Jin
Source: check_circle
Crossref

HDAC8 Enhances the Function of HIF‐2α by Deacetylating ETS1 to Decrease the Sensitivity of TKIs in ccRCC

Advanced Science
2024-07-29 | Journal article
DOI: 10.1002/advs.202401142
Contributors: Kang Qian; Wei Li; Shangqing Ren; Weilin Peng; Bei Qing; Xinlin Liu; Xiong Wei; Liang Zhu; Yapeng Wang; Xin Jin
Source: check_circle
Crossref

Retinoblastoma-associated protein is important for TRIM24-mediated activation of the mTOR signaling pathway through DUSP2 action in prostate cancer

Cell Death & Differentiation
2024-05 | Journal article
DOI: 10.1038/s41418-024-01282-w
Contributors: Da Ren; Wei Li; Ruijiang Zeng; Xinlin Liu; Huaiyuan Liang; Wei Xiong; Chunguang Yang; Xin Jin
Source: check_circle
Crossref

ZDHHC20-mediated S-palmitoylation of YTHDF3 stabilizes MYC mRNA to promote pancreatic cancer progression

Nature Communications
2024-05-31 | Journal article
DOI: 10.1038/s41467-024-49105-3
Contributors: Huan Zhang; Yan Sun; Zhaokai Wang; Xiaoju Huang; Lu Tang; Ke Jiang; Xin Jin
Source: check_circle
Crossref

MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression

The EMBO Journal
2023-12 | Journal article
DOI: 10.15252/embj.2023114558
Contributors: Yan Sun; Xin Jin; Junpeng Meng; Feng Guo; Taoyu Chen; Xiaoyan Zhao; Heshui Wu; Dianyun Ren
Source: check_circle
Crossref

Targeting CBX3 with a Dual BET/PLK1 Inhibitor Enhances the Antitumor Efficacy of CDK4/6 Inhibitors in Prostate Cancer

Advanced Science
2023-12 | Journal article
DOI: 10.1002/advs.202302368
Contributors: Huaiyuan Liang; Chunguang Yang; Ruijiang Zeng; Yingqiu Song; Jianxi Wang; Wei Xiong; Binyuan Yan; Xin Jin
Source: check_circle
Crossref

Data from ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma

2023-06-15 | Preprint
DOI: 10.1158/0008-5472.c.6678641.v2
Contributors: Yan Sun; Liang Zhu; Pian Liu; Huan Zhang; Feng Guo; Xin Jin
Source: check_circle
Crossref

Supplementary Data from ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma

2023-06-15 | Preprint
DOI: 10.1158/0008-5472.23522258
Contributors: Yan Sun; Liang Zhu; Pian Liu; Huan Zhang; Feng Guo; Xin Jin
Source: check_circle
Crossref

Supplementary Data from ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma

2023-06-15 | Preprint
DOI: 10.1158/0008-5472.23522258.v1
Contributors: Yan Sun; Liang Zhu; Pian Liu; Huan Zhang; Feng Guo; Xin Jin
Source: check_circle
Crossref

ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma

Cancer Research
2023-06-15 | Journal article
DOI: 10.1158/0008-5472.CAN-22-3105
Contributors: Yan Sun; Liang Zhu; Pian Liu; Huan Zhang; Feng Guo; Xin Jin
Source: check_circle
Crossref

Data from ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma

2023-06-02 | Preprint
DOI: 10.1158/0008-5472.c.6678641.v1
Contributors: Yan Sun; Liang Zhu; Pian Liu; Huan Zhang; Feng Guo; Xin Jin
Source: check_circle
Crossref

Supplementary Data from ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma

2023-06-02 | Preprint
DOI: 10.1158/0008-5472.23289563
Contributors: Yan Sun; Liang Zhu; Pian Liu; Huan Zhang; Feng Guo; Xin Jin
Source: check_circle
Crossref

Supplementary Data from ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma

2023-06-02 | Preprint
DOI: 10.1158/0008-5472.23289563.v1
Contributors: Yan Sun; Liang Zhu; Pian Liu; Huan Zhang; Feng Guo; Xin Jin
Source: check_circle
Crossref

The YTHDC1/GLUT3/RNF183 axis forms a positive feedback loop that modulates glucose metabolism and bladder cancer progression

Experimental & Molecular Medicine
2023-06-01 | Journal article
DOI: 10.1038/s12276-023-00997-z
Contributors: Bin Yan; Xurui Li; Mou Peng; Yali Zuo; Yinhuai Wang; Pian Liu; Weigang Ren; Xin Jin
Source: check_circle
Crossref

Data from HDAC5 Loss Impairs RB Repression of Pro-Oncogenic Genes and Confers CDK4/6 Inhibitor Resistance in Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.c.6513222
Contributors: Yingke Zhou; Xin Jin; Jian Ma; Donglin Ding; Zhenlin Huang; Haoyue Sheng; Yuqian Yan; Yunqian Pan; Ting Wei; Liguo Wang et al.
Source: check_circle
Crossref

Data from HDAC5 Loss Impairs RB Repression of Pro-Oncogenic Genes and Confers CDK4/6 Inhibitor Resistance in Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.c.6513222.v1
Contributors: Yingke Zhou; Xin Jin; Jian Ma; Donglin Ding; Zhenlin Huang; Haoyue Sheng; Yuqian Yan; Yunqian Pan; Ting Wei; Liguo Wang et al.
Source: check_circle
Crossref

Supplementary Data from HDAC5 Loss Impairs RB Repression of Pro-Oncogenic Genes and Confers CDK4/6 Inhibitor Resistance in Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22429044.v1
Contributors: Yingke Zhou; Xin Jin; Jian Ma; Donglin Ding; Zhenlin Huang; Haoyue Sheng; Yuqian Yan; Yunqian Pan; Ting Wei; Liguo Wang et al.
Source: check_circle
Crossref

Supplementary Data from HDAC5 Loss Impairs RB Repression of Pro-Oncogenic Genes and Confers CDK4/6 Inhibitor Resistance in Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22429044
Contributors: Yingke Zhou; Xin Jin; Jian Ma; Donglin Ding; Zhenlin Huang; Haoyue Sheng; Yuqian Yan; Yunqian Pan; Ting Wei; Liguo Wang et al.
Source: check_circle
Crossref

The E3 ligase RBCK1 reduces the sensitivity of ccRCC to sunitinib through the ANKRD35-MITD1-ANXA1 axis

Oncogene
2023-03-24 | Journal article
DOI: 10.1038/s41388-023-02613-w
Contributors: Yapeng Wang; Mou Peng; Yawen Zhong; Wei Xiong; Liang Zhu; Xin Jin
Source: check_circle
Crossref

TRIM15 forms a regulatory loop with the AKT/FOXO1 axis and LASP1 to modulate the sensitivity of HCC cells to TKIs

Cell Death & Disease
2023-01-20 | Journal article
DOI: 10.1038/s41419-023-05577-7
Contributors: Chong Yang; Xin Jin; Xingchao Liu; Gang Wu; Wenhao Yang; Beichuan Pang; Jipeng Jiang; Dongxu Liao; Yu Zhang
Source: check_circle
Crossref

Downregulation of CBX7 induced by EZH2 upregulates FGFR3 expression to reduce sensitivity to cisplatin in bladder cancer

British Journal of Cancer
2023-01-19 | Journal article
DOI: 10.1038/s41416-022-02058-0
Contributors: Jiannan Ren; Haixin Yu; Wei Li; Xin Jin; Bin Yan
Source: check_circle
Crossref
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CBX3 Regulated By YBX1 Promotes Smoking-induced Pancreatic Cancer Progression via Inhibiting SMURF2 Expression

International Journal of Biological Sciences
2022 | Journal article
DOI: 10.7150/ijbs.68995
EID:

2-s2.0-85131157569

Part of ISSN: 14492288
Contributors: Zhang, H.; Yu, H.; Ren, D.; Sun, Y.; Guo, F.; Cai, H.; Zhou, C.; Zhou, Y.; Jin, X.; Wu, H.
Source: Self-asserted source
Xin Jin via Scopus - Elsevier

HDAC5 modulates PD-L1 expression and cancer immunity via p65 deacetylation in pancreatic cancer

Theranostics
2022 | Journal article
DOI: 10.7150/thno.69444
EID:

2-s2.0-85124462317

Part of ISSN: 18387640
Contributors: Zhou, Y.; Jin, X.; Yu, H.; Qin, G.; Pan, P.; Zhao, J.; Chen, T.; Liang, X.; Sun, Y.; Wang, B. et al.
Source: Self-asserted source
Xin Jin via Scopus - Elsevier

OTUD1 stabilizes PTEN to inhibit the PI3K/AKT and TNF-alpha/NF-kappaB signaling pathways and sensitize ccRCC to TKIs

International Journal of Biological Sciences
2022 | Journal article
DOI: 10.7150/ijbs.68980
EID:

2-s2.0-85126419353

Part of ISSN: 14492288
Contributors: Liu, W.; Yan, B.; Yu, H.; Ren, J.; Peng, M.; Zhu, L.; Wang, Y.; Jin, X.; Yi, L.
Source: Self-asserted source
Xin Jin via Scopus - Elsevier

Overexpressed integrin alpha 2 inhibits the activation of the transforming growth factor β pathway in pancreatic cancer via the TFCP2-SMAD2 axis

Journal of Experimental and Clinical Cancer Research
2022 | Journal article
DOI: 10.1186/s13046-022-02286-5
EID:

2-s2.0-85125157374

Part of ISSN: 17569966
Contributors: Cai, H.; Guo, F.; Wen, S.; Jin, X.; Wu, H.; Ren, D.
Source: Self-asserted source
Xin Jin via Scopus - Elsevier

S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K/AKT pathway

Cell Reports
2022 | Journal article
DOI: 10.1016/j.celrep.2022.111194
EID:

2-s2.0-85135885175

Part of ISSN: 22111247
Contributors: Sun, Y.; Zhang, H.; Meng, J.; Guo, F.; Ren, D.; Wu, H.; Jin, X.
Source: Self-asserted source
Xin Jin via Scopus - Elsevier

Smoking-associated upregulation of CBX3 suppresses ARHGAP24 expression to activate Rac1 signaling and promote tumor progression in lung adenocarcinoma

Oncogene
2022 | Journal article
DOI: 10.1038/s41388-021-02114-8
EID:

2-s2.0-85119345203

Part of ISSN: 14765594 09509232
Contributors: Jin, X.; Zhang, B.; Zhang, H.; Yu, H.
Source: Self-asserted source
Xin Jin via Scopus - Elsevier

Targeted Delivery of PD-L1-Derived Phosphorylation-Mimicking Peptides by Engineered Biomimetic Nanovesicles to Enhance Osteosarcoma Treatment

Advanced Healthcare Materials
2022 | Journal article
DOI: 10.1002/adhm.202200955
EID:

2-s2.0-85139256388

Part of ISSN: 21922659 21922640
Contributors: Wu, W.; Guo, H.; Jing, D.; Zhang, Z.; Zhang, Z.; Pu, F.; Yang, W.; Jin, X.; Huang, X.; Shao, Z.
Source: Self-asserted source
Xin Jin via Scopus - Elsevier

The RNF26/CBX7 axis modulates the TNF pathway to promote cell proliferation and regulate sensitivity to TKIs in ccRCC

International Journal of Biological Sciences
2022 | Journal article
DOI: 10.7150/ijbs.69325
EID:

2-s2.0-85127300331

Part of ISSN: 14492288
Contributors: Liu, W.; Wang, H.; Jian, C.; Li, W.; Ye, K.; Ren, J.; Zhu, L.; Wang, Y.; Jin, X.; Yi, L.
Source: Self-asserted source
Xin Jin via Scopus - Elsevier

A novel FBW7/NFAT1 axis regulates cancer immunity in sunitinib-resistant renal cancer by inducing PD-L1 expression

Journal of Experimental & Clinical Cancer Research
2022-12 | Journal article
DOI: 10.1186/s13046-022-02253-0
Contributors: Wentao Liu; Dianyun Ren; Wei Xiong; Xin Jin; Liang Zhu
Source: check_circle
Crossref
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Global crotonylome reveals hypoxia-mediated lamin A crotonylation regulated by HDAC6 in liver cancer

Cell Death & Disease
2022-08-17 | Journal article
DOI: 10.1038/s41419-022-05165-1
Contributors: Dan Zhang; Jing Tang; Yunhong Xu; Xiaoju Huang; Yilin Wang; Xin Jin; Gang Wu; Pian Liu
Source: check_circle
Crossref
grade
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Deubiquitination of FBP1 by USP7 blocks FBP1–DNMT1 interaction and decreases the sensitivity of pancreatic cancer cells to PARP inhibitors

Molecular Oncology
2022-04 | Journal article
DOI: 10.1002/1878-0261.13149
Contributors: Xiang Cheng; Bin Zhang; Feng Guo; Heshui Wu; Xin Jin
Source: check_circle
Crossref
grade
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The RBPJ/DAPK3/UBE3A signaling axis induces PBRM1 degradation to modulate the sensitivity of renal cell carcinoma to CDK4/6 inhibitors

Cell Death & Disease
2022-04-02 | Journal article
DOI: 10.1038/s41419-022-04760-6
Contributors: Wentao Liu; Bin Zhang; Dan Zhang; Feng Guo; Kun Ye; Liang Zhu; Xin Jin
Source: check_circle
Crossref
grade
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USP22‐mediated deubiquitination of PTEN inhibits pancreatic cancer progression by inducing p21 expression

Molecular Oncology
2022-03 | Journal article
DOI: 10.1002/1878-0261.13137
Contributors: Dianyun Ren; Yan Sun; Dan Li; Heshui Wu; Xin Jin
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

FGD3 binds with HSF4 to suppress p65 expression and inhibit pancreatic cancer progression

Oncogene
2022-02-04 | Journal article
DOI: 10.1038/s41388-021-02140-6
Contributors: Feng Guo; Xiang Cheng; Boping Jing; Heshui Wu; Xin Jin
Source: check_circle
Crossref
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Items per page:
Page 1 of 3

Peer review (20 reviews for 9 publications/grants)

Review activity for Advanced science. (3)
Review activity for Cell death and disease. (2)
Review activity for Cell death discovery. (1)
Review activity for Cell reports medicine. (1)
Review activity for Cell reports. (1)
Review activity for Experimental and molecular medicine (1)
Review activity for iScience. (3)
Review activity for Journal of experimental & clinical cancer research. (7)
Review activity for Oncogene. (1)
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