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Works (11)

Rechallenging with anti-PD-1 therapy in advanced renal cell carcinoma.

Lancet (London, England)
2024-09-12 | Journal article
DOI: 10.1016/s0140-6736(24)01866-x
PMID: 39284326
Contributors: Yochum ZA; Braun DA
Source: Self-asserted source
Zachary Yochum

TWIST1 is a critical downstream target of the HGF/MET pathway and is required for MET driven acquired resistance in oncogene driven lung cancer.

Oncogene
2024-03-01 | Journal article
DOI: 10.1038/s41388-024-02987-5
PMID: 38485737
PMC: PMC11068584
Contributors: Kumar V; Yochum ZA; Devadassan P; Huang EH; Miller E; Baruwal R; Rumde PH; GaitherDavis AL; Stabile LP; Timothy Burns
Source: Self-asserted source
Zachary Yochum

Alternative splicing of HER2: a novel mediator of EGFR TKI resistance.

Translational lung cancer research
2020-08-01 | Journal article
DOI: 10.21037/tlcr-20-618
PMID: 32953533
PMC: PMC7481647
Contributors: Yochum ZA; Villaruz LC
Source: Self-asserted source
Zachary Yochum

Hormone gene signature guides a novel therapeutic opportunity to improve sensitivity to HER family inhibition in lung cancer.

Translational lung cancer research
2020-08-01 | Journal article
DOI: 10.21037/tlcr-20-617
PMID: 32953532
PMC: PMC7481617
Contributors: Yochum ZA; Stabile LP
Source: Self-asserted source
Zachary Yochum

TWIST1 regulation of circRNA: a novel mechanism to promote epithelial-mesenchymal transition in hepatocellular carcinoma.

Non-coding RNA investigation
2018-12-19 | Journal article
DOI: 10.21037/ncri.2018.12.01
PMID: 30734026
PMC: PMC6363344
Contributors: Yochum ZA; Burns TF
Source: Self-asserted source
Zachary Yochum

Targeting the EMT transcription factor TWIST1 overcomes resistance to EGFR inhibitors in EGFR-mutant non-small-cell lung cancer.

Oncogene
2018-08-31 | Journal article
DOI: 10.1038/s41388-018-0482-y
PMID: 30171258
PMC: PMC6358506
Contributors: Yochum ZA; Cades J; Hailun Wang; Chatterjee S; BW Simons; O'Brien JP; Khetarpal SK; Lemtiri-Chlieh G; Kayla Myers Chen; Huang EH et al.
Source: Self-asserted source
Zachary Yochum

TMEM16A/ANO1 Inhibits Apoptosis Via Downregulation of Bim Expression.

Clinical cancer research : an official journal of the American Association for Cancer Research
2017-09-12 | Journal article
DOI: 10.1158/1078-0432.ccr-17-1561
PMID: 28899969
PMC: PMC5898434
Contributors: Godse NR; Khan N; Yochum ZA; Roberto Gomez Casal; Kemp C; Daniel Shiwarski; Seethala RS; Kulich S; Seshadri M; Burns TF et al.
Source: Self-asserted source
Zachary Yochum

A First-in-Class TWIST1 Inhibitor with Activity in Oncogene-Driven Lung Cancer.

Molecular cancer research : MCR
2017-08-29 | Journal article
DOI: 10.1158/1541-7786.mcr-17-0298
PMID: 28851812
PMC: PMC5712248
Contributors: Yochum ZA; Cades J; Lucia Mazzacurati; Neil M. Neumann, M.D., Ph.D.; Khetarpal SK; Chatterjee S; Hailun Wang; Attar MA; Huang EH; Chatley SN et al.
Source: Self-asserted source
Zachary Yochum

Paradoxical functions of ZEB1 in <i>EGFR</i>-mutant lung cancer: tumor suppressor and driver of therapeutic resistance.

Journal of thoracic disease
2016-11-01 | Journal article
DOI: 10.21037/jtd.2016.11.59
PMID: 28066651
PMC: PMC5179406
Contributors: Yochum ZA; Socinski MA; Burns TF
Source: Self-asserted source
Zachary Yochum

High expression of orphan nuclear receptor NR4A1 in a subset of ovarian tumors with worse outcome.

Gynecologic oncology
2016-03-11 | Journal article
DOI: 10.1016/j.ygyno.2016.02.030
PMID: 26946093
PMC: PMC5154956
Contributors: Evan Delgado; Boisen MM; Laskey R; Chen R; Song C; Sallit J; Yochum ZA; Courtney Andersen; Matthew J. Sikora; Wagner J et al.
Source: Self-asserted source
Zachary Yochum

P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells.

Cancers
2012-04-25 | Journal article
DOI: 10.3390/cancers4020475
PMID: 22582143
PMC: PMC3348653
Contributors: Hwang M; Peddibhotla S; McHenry P; Chang P; Yochum Z; Park KU; James C Sears; Vargo-Gogola T
Source: Self-asserted source
Zachary Yochum
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