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SciProfiles: 3762793
ResearcherID: E-4160-2015
Scopus Author ID: 6603111613

Biography

Research is focused primarily on understanding the molecular mechanisms governing the repair of various types of DNA damage. Bacterial, yeast and human repair pathways are studied using a variety of genetic and biochemical tools with the primary emphasis being determination of macromolecular structure using X-ray crystallography. With expertise in protein structure determination, a significant effort is also placed on developing new chemotherapeutics using structure-based drug design methods.

Activities

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Employment (2)

Western University: London, ON, CA

2014-07-01 to present | Faculty (Biochemistry)
Employment
Source: Self-asserted source
Murray Junop

McMaster University: Hamilton, ON, CA

2001-11-01 to 2014-06-31 | Faculty (Biochemistry and Biomedical Sciences)
Employment
Source: Self-asserted source
Murray Junop

Education and qualifications (3)

NIH Clinical Center: Bethesda, MD, US

1997-10-01 to 2001-10-31 | Postdoctoral (NIDDK/LMB)
Education
Source: Self-asserted source
Murray Junop

Western University: London, ON, CA

1991-09-01 to 1997-09-31 | PhD (Biochemistry)
Education
Source: Self-asserted source
Murray Junop

Ryerson University: Toronto, ON, CA

1987-09-01 to 1991-04-31 | BSc (Chemistry and Biochemistry)
Education
Source: Self-asserted source
Murray Junop

Funding (31)

Molecular Mechanisms of DNA repair in Deinococcus radiodurans

2022-04-01 to 2023-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.13592792
GRANT_NUMBER: grant.13592792
Source: Self-asserted source
Murray Junop via DimensionsWizard

Molecular Mechanisms of DNA repair in Deinococcus radiodurans

2021-04-01 to 2022-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.13004162
GRANT_NUMBER: grant.13004162
Source: Self-asserted source
Murray Junop via DimensionsWizard

Molecular Mechanisms of Non-homologous DNA End-joining

2019-10-01 to 2024-09-30 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.8527186
GRANT_NUMBER:

grant.8527186
Source: Self-asserted source
Murray Junop via DimensionsWizard

Molecular Mechanisms of DNA repair in Deinococcus radiodurans

2018-04-01 to 2021-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.8653532
GRANT_NUMBER: grant.8653532
Source: Self-asserted source
Murray Junop via DimensionsWizard

High-throughput Crystallization Imaging System

2018-04-01 to 2019-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.8650290
GRANT_NUMBER: grant.8650290
Source: Self-asserted source
Murray Junop via DimensionsWizard

Ion Mobility Mass Spectrometer for Studying Protein Structure and Dynamics

2017-04-01 to 2018-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7709390
GRANT_NUMBER: grant.7709390
Source: Self-asserted source
Murray Junop via DimensionsWizard

Operations and Maintenance Support for a Regional Protein Characterization Facility

2016-04-01 to 2017-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.6972853
GRANT_NUMBER: grant.6972853
Source: Self-asserted source
Murray Junop via DimensionsWizard

Robotic Instrumentation to Establish Workflows for Systematic Cell-Based Analyses.

2016-04-01 to 2017-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.6972863
GRANT_NUMBER: grant.6972863
Source: Self-asserted source
Murray Junop via DimensionsWizard

Identification of SNM1A inhibitors with adjuvant anticancer activity

2013-08-01 to 2015-07-31 | Grant
Canadian Cancer Society (Toronto, CA)
URL: https://app.dimensions.ai/details/grant/grant.7640405
GRANT_NUMBER:

grant.7640405
Source: Self-asserted source
Murray Junop via DimensionsWizard

Molecular mechanism of extreme DNA damage resistance in Deinococcus spp.

2013-04-01 to 2018-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.3657328
GRANT_NUMBER: grant.3657328
Source: Self-asserted source
Murray Junop via DimensionsWizard

Isothermal titration calorimeter

2012-04-01 to 2013-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.2822258
GRANT_NUMBER: grant.2822258
Source: Self-asserted source
Murray Junop via DimensionsWizard

Macromolecular crystallization and X-ray diffraction facility

2010-06-15 to present | Grant
Canada Foundation for Innovation (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.6763311
GRANT_NUMBER:

26332
Source: Self-asserted source
Murray Junop via DimensionsWizard

Structural and Biochemical Characterization of Human Pleckstrin: a new target for treatment of inflammation in cardiovascular disease.

2009-09-01 to 2010-08-31 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7639326
GRANT_NUMBER:

grant.7639326
Source: Self-asserted source
Murray Junop via DimensionsWizard

Unraveling the Molecular Mechanisms of Non-homologous DNA End-joining

2008-10-01 to 2018-09-30 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.6809228
GRANT_NUMBER:

grant.6809228
Source: Self-asserted source
Murray Junop via DimensionsWizard

Molecular mechanism(s) of DNA repair in Deinococcus radiodurans

2008-04-01 to 2013-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.2939646
GRANT_NUMBER: grant.2939646
Source: Self-asserted source
Murray Junop via DimensionsWizard

Characterization of protein samples using dynamic light scattering

2008-04-01 to 2009-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.2830838
GRANT_NUMBER: grant.2830838
Source: Self-asserted source
Murray Junop via DimensionsWizard

Branding Name: NET in Antibiotic Adjuvants Title: Antibiotic Adjuvants: Overcoming multi-drug Resistance in Gram

2008-01-01 to 2012-12-31 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7666499
GRANT_NUMBER:

grant.7666499
Source: Self-asserted source
Murray Junop via DimensionsWizard

Characterizing the regulatory interaction between the platelet proteins pleckstrin and inositol polyphosphate 5-phosphatase I

2007-09-01 to 2009-08-31 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7639324
GRANT_NUMBER:

grant.7639324
Source: Self-asserted source
Murray Junop via DimensionsWizard

Structural and Functional Studies of the Human Hematopoietic Platelet Activating Factor, Pleckstrin

2006-09-01 to 2007-08-31 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7639325
GRANT_NUMBER:

grant.7639325
Source: Self-asserted source
Murray Junop via DimensionsWizard

Consortium for operation of a protein crystallographic synchrotron beamline

2006-04-01 to 2009-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.2855288
GRANT_NUMBER: grant.2855288
Source: Self-asserted source
Murray Junop via DimensionsWizard

Consortium for the operation of a protein crystallographic synchrotron beamline

2006-04-01 to 2009-03-31 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7620581
GRANT_NUMBER:

grant.7620581
Source: Self-asserted source
Murray Junop via DimensionsWizard

X-ray crystallographic studies of biomedically relevant proteins

2005-10-01 to 2010-09-30 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7635909
GRANT_NUMBER:

grant.7635909
Source: Self-asserted source
Murray Junop via DimensionsWizard

Consortium for operation of a protein crystallographic synchrotron beamline

2004-04-01 to 2006-03-31 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7661551
GRANT_NUMBER:

grant.7661551
Source: Self-asserted source
Murray Junop via DimensionsWizard

Toward Designed Antibiotics: Mechanisms and Inhibition of PEP Utilizing Enzymes

2003-10-01 to 2016-09-30 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7620772
GRANT_NUMBER:

grant.7620772
Source: Self-asserted source
Murray Junop via DimensionsWizard

Crystallographic Studies of DNA Repair Proteins and Novel Antibiotic Inhibitor-Protein Complexes

2003-04-30 to present | Grant
Canada Foundation for Innovation (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.6763373
GRANT_NUMBER:

7760
Source: Self-asserted source
Murray Junop via DimensionsWizard

Consortium for operation of a protein crystallographic synchrotron beamline

2003-04-01 to 2006-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.2927487
GRANT_NUMBER: grant.2927487
Source: Self-asserted source
Murray Junop via DimensionsWizard

Canadian Bacterial Diseases Network (CBDN)

2003-04-01 to 2005-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.2962711
GRANT_NUMBER: grant.2962711
Source: Self-asserted source
Murray Junop via DimensionsWizard

Crystallographic studies of DNA repair proteins involved in non-homologous DNA end joining

2002-04-01 to 2008-03-31 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7640407
GRANT_NUMBER:

grant.7640407
Source: Self-asserted source
Murray Junop via DimensionsWizard

Consortium For Operation of a Protein Crystallographic Synchrotron Beam Line

1999-04-01 to 2004-03-31 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7661552
GRANT_NUMBER:

grant.7661552
Source: Self-asserted source
Murray Junop via DimensionsWizard

Macromolecular Crystallography at the National Synchrotron Light Source

1998-09-30 to 2013-06-30 | Grant
National Center for Advancing Translational Sciences (Rockville, US)
URL: https://app.dimensions.ai/details/grant/grant.2439914
GRANT_NUMBER: P41RR012408
Source: Self-asserted source
Murray Junop via DimensionsWizard

Crystallographic studies of Tn10 transposition

1997-10-15 to 2000-10-14 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7640406
GRANT_NUMBER:

grant.7640406
Source: Self-asserted source
Murray Junop via DimensionsWizard
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