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Employment (3)

Ludwig-Maximilians-Universität München: Munich, Bavaria, DE

2022-03-01 to present | Junior Group Leader (Institute of Chemical Epigenetics - Munich)
Employment
Source: Self-asserted source
Pascal Giehr

ETH Zurich: Zurich, CH

2020-07-01 to 2022-02-28 (Laboratory of Nutrition and Metabolic Epigenetics)
Employment
Source: Self-asserted source
Pascal Giehr

Universität des Saarlandes: Saarbrücken, Saarland, DE

2013 to 2020 (Department of Genetics and Epigenetics)
Employment
Source: Self-asserted source
Pascal Giehr

Funding (2)

Simultaneous identification of distinct DNA modifications using 3rd-generation Sequencing

2020-10-01 to 2021-09-30 | Grant
Swiss National Science Foundation (Bern, CH)
URL: https://app.dimensions.ai/details/grant/grant.9407440
GRANT_NUMBER: 195722
Source: Self-asserted source
Pascal Giehr via DimensionsWizard

SFB 1309:  Chemical Biology of Epigenetic Modifications

2018-01-01 to present | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
URL: https://app.dimensions.ai/details/grant/grant.7706897
GRANT_NUMBER: 325871075
Source: Self-asserted source
Pascal Giehr via DimensionsWizard

Works (17)

Robust Bisulfite‐Free Single‐Molecule Real‐Time Sequencing of Methyldeoxycytidine Based on a Novel hpTet3 Enzyme

Angewandte Chemie International Edition
2024-12-20 | Journal article
DOI: 10.1002/anie.202418500
Contributors: Hanife Sahin; Raheleh Salehi; Shariful Islam; Markus Müller; Pascal Giehr; Thomas Carell
Source: check_circle
Crossref

Robuste Bisulfit‐freie Einzelmolekül‐Echtzeitsequenzierung von Methyldesoxycytidin auf der Grundlage eines neuartigen hpTet3‐Enzyms

Angewandte Chemie
2024-12-20 | Journal article
DOI: 10.1002/ange.202418500
Contributors: Hanife Sahin; Raheleh Salehi; Shariful Islam; Markus Müller; Pascal Giehr; Thomas Carell
Source: check_circle
Crossref

A comprehensive approach for genome-wide efficiency profiling of DNA modifying enzymes

Cell Reports Methods
2022-03 | Journal article
DOI: 10.1016/j.crmeth.2022.100187
Part of ISSN: 2667-2375
Source: Self-asserted source
Pascal Giehr

Dnmt1 has de novo activity targeted to transposable elements

Nature Structural & Molecular Biology
2021-07 | Journal article
DOI: 10.1038/s41594-021-00603-8
Part of ISSN: 1545-9993
Part of ISSN: 1545-9985
Source: Self-asserted source
Pascal Giehr

Genome wide efficiency profiling reveals modulation of maintenance and de novo methylation by Tets

2020-08-07 | Preprint
DOI: 10.1101/2020.08.06.236307
Source: Self-asserted source
Pascal Giehr
grade
Preferred source (of 2)‎

A Hybrid HMM Approach for the Dynamics of DNA Methylation

Hybrid Systems Biology
2019 | Book chapter
DOI: 10.1007/978-3-030-28042-0_8
Part of ISBN: 9783030280413
Part of ISBN: 9783030280420
Part of ISSN: 0302-9743
Part of ISSN: 1611-3349
Source: Self-asserted source
Pascal Giehr

Hidden Markov Modelling Reveals Neighborhood Dependence of Dnmt3a and 3b Activity

IEEE/ACM Transactions on Computational Biology and Bioinformatics
2019-09-01 | Journal article
DOI: 10.1109/tcbb.2019.2910814
Part of ISSN: 1545-5963
Part of ISSN: 1557-9964
Part of ISSN: 2374-0043
Source: Self-asserted source
Pascal Giehr

Hairpin Bisulfite Sequencing: Synchronous Methylation Analysis on Complementary DNA Strands of Individual Chromosomes

Methods in Molecular Biology
2018 | Book chapter
DOI: 10.1007/978-1-4939-7481-8_29
Part of ISBN: 9781493974795
Part of ISBN: 9781493974818
Part of ISSN: 1064-3745
Part of ISSN: 1940-6029
Source: Self-asserted source
Pascal Giehr

Genomic integrity of ground‐state pluripotency

Journal of Cellular Biochemistry
2018-12 | Journal article
DOI: 10.1002/jcb.27296
Part of ISSN: 0730-2312
Part of ISSN: 1097-4644
Source: Self-asserted source
Pascal Giehr

Two are better than one: HPoxBS - hairpin oxidative bisulfite sequencing

Nucleic Acids Research
2018-09-06 | Journal article
DOI: 10.1093/nar/gky422
Part of ISSN: 0305-1048
Part of ISSN: 1362-4962
Source: Self-asserted source
Pascal Giehr

CD137+CD154− Expression As a Regulatory T Cell (Treg)-Specific Activation Signature for Identification and Sorting of Stable Human Tregs from In Vitro Expansion Cultures

Frontiers in Immunology
2018-02-07 | Journal article
DOI: 10.3389/fimmu.2018.00199
Part of ISSN: 1664-3224
Source: Self-asserted source
Pascal Giehr

A Stochastic Model for the Formation of Spatial Methylation Patterns

Computational Methods in Systems Biology
2017 | Book chapter
DOI: 10.1007/978-3-319-67471-1_10
Part of ISBN: 9783319674704
Part of ISBN: 9783319674711
Part of ISSN: 0302-9743
Part of ISSN: 1611-3349
Source: Self-asserted source
Pascal Giehr

Histone and DNA methylation control by H3 serine 10/threonine 11 phosphorylation in the mouse zygote

Epigenetics & Chromatin
2017-12 | Journal article
DOI: 10.1186/s13072-017-0112-x
Part of ISSN: 1756-8935
Source: Self-asserted source
Pascal Giehr

H(O)TA: estimation of DNA methylation and hydroxylation levels and efficiencies from time course data

Bioinformatics
2017-01-27 | Journal article
DOI: 10.1093/bioinformatics/btx042
Part of ISSN: 1367-4803
Part of ISSN: 1460-2059
Source: Self-asserted source
Pascal Giehr

MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs

Cell Reports
2016-09 | Journal article
DOI: 10.1016/j.celrep.2016.08.087
Part of ISSN: 2211-1247
Source: Self-asserted source
Pascal Giehr

The Influence of Hydroxylation on Maintaining CpG Methylation Patterns: A Hidden Markov Model Approach

PLOS Computational Biology
2016-05-25 | Journal article
DOI: 10.1371/journal.pcbi.1004905
Part of ISSN: 1553-7358
Source: Self-asserted source
Pascal Giehr

Active Demethylation of the Foxp3 Locus Leads to the Generation of Stable Regulatory T Cells within the Thymus

The Journal of Immunology
2013-04-01 | Journal article
DOI: 10.4049/jimmunol.1203473
Part of ISSN: 0022-1767
Part of ISSN: 1550-6606
Source: Self-asserted source
Pascal Giehr

Peer review (1 review for 1 publication/grant)

Review activity for EMBO reports. (1)
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