Personal information

Other IDs

Scopus Author ID: 55725719500
Scopus Author ID: 56208708700

Activities

Collapse all

Employment (2)

Shanghai Institute of Materia Medica Chinese Academy of Sciences: Shanghai, CN

2011-03-01 to present | Professor (Antitumor Pharmacology)
Employment
Source: Self-asserted source
min huang

Dana Farber Cancer Institute: Boston, MA, US

2008-01-14 to 2011-02-20 | Postdoc (Radiation Oncology)
Employment
Source: Self-asserted source
min huang

Education and qualifications (1)

Shanghai Institute of Materia Medica Chinese Academy of Sciences: Shanghai, CN

2002-09 to 2007-06 | Ph.D.
Education
Source: Self-asserted source
min huang

Works (35)

A region-confined PROTAC nanoplatform for spatiotemporally tunable protein degradation and enhanced cancer therapy

Nature Communications
2024-08-04 | Journal article
DOI: 10.1038/s41467-024-50735-w
Contributors: Jing Gao; Xingyu Jiang; Shumin Lei; Wenhao Cheng; Yi Lai; Min Li; Lei Yang; Peifeng Liu; Xiao-hua Chen; Min Huang et al.
Source: check_circle
Crossref

Oncometabolites in cancer: from cancer cells to the tumor microenvironment

Holistic Integrative Oncology
2024-06-11 | Journal article
DOI: 10.1007/s44178-024-00096-7
Contributors: Luoyi Chen; Min Huang
Source: check_circle
Crossref

Low-Dose Chemotherapy Preferentially Shapes the Ileal Microbiome and Augments the Response to Immune Checkpoint Blockade by Activating AIM2 Inflammasome in Ileal Epithelial Cells.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2024-01-08 | Journal article | Author
DOI: 10.1002/advs.202304781
PMID: 38189627
Contributors: Pu C; Li Y; Fu Y; Yan Y; Tao S; Tang S; Gai X; Ding Z; Gan Z; Liu Y et al.
Source: Self-asserted source
min huang

Discovery of Dual Function Agents That Exhibit Anticancer Activity via Catastrophic Nicotinamide Adenine Dinucleotide Depletion.

Journal of medicinal chemistry
2023-12-07 | Journal article
DOI: 10.1021/acs.jmedchem.3c01362
PMID: 38060985
Contributors: Fu Y; Huang Y; Zhou C; Li X; guoqiang dong; Huang M; Ding J; Chunquan Sheng
Source: Self-asserted source
min huang

Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis.

Pharmacological research
2023-10-14 | Journal article
DOI: 10.1016/j.phrs.2023.106955
PMID: 37820855
Contributors: Tang S; Duan Y; Yuan T; Hu Y; Yuan L; Shen N; Fu Y; Pu C; Wang X; Xu J et al.
Source: Self-asserted source
min huang

Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer.

Acta pharmaceutica Sinica. B
2023-03-11 | Journal article
DOI: 10.1016/j.apsb.2023.03.009
PMID: 37425067
PMC: PMC10326305
Contributors: Wang X; Xu J; Sun Y; Cao S; Zeng H; Jin N; Shou M; Tang S; Chen Y; Huang M
Source: Self-asserted source
min huang
grade
Preferred source (of 2)‎

Metabolic Regulation of CD8+T Cells: From Mechanism to Therapy

Antioxidants & Redox Signaling
2022-12-01 | Journal article
DOI: 10.1089/ars.2022.0040
Contributors: Ying Zheng; Xiaomin Wang; Min Huang
Source: check_circle
Crossref

SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors.

Cell research
2022-04-22 | Journal article | Author
DOI: 10.1038/s41422-022-00650-w
PMID: 35459936
Contributors: Wang X; Chen Z; Xu J; Tang S; An N; Jiang L; Zhang Y; Zhang S; Zhang Q; Shen Y et al.
Source: Self-asserted source
min huang

NAMPT-targeting PROTAC promotes antitumor immunity <i>via</i> suppressing myeloid-derived suppressor cell expansion.

Acta pharmaceutica Sinica. B
2021-12-31 | Journal article
DOI: 10.1016/j.apsb.2021.12.017
PMID: 35755293
PMC: PMC9214341
Contributors: min huang; Wu Y; Pu C; Fu Y; Dong G; Huang M; Sheng C
Source: Self-asserted source
min huang
grade
Preferred source (of 2)‎

A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies.

Molecular cell
2021-08-09 | Journal article
DOI: 10.1016/j.molcel.2021.07.021
PMID: 34375582
Contributors: min huang; Liu Z; Liu Y; Qian L; Jiang S; Gai X; Ye S; Chen Y; Wang X; Zhai L et al.
Source: Self-asserted source
min huang

Natural Products in Cancer Therapy: Past, Present and Future

Natural Products and Bioprospecting
2021-02 | Journal article
DOI: 10.1007/s13659-020-00293-7
Contributors: Min Huang; Jin-Jian Lu; Jian Ding
Source: check_circle
Crossref

Harnessing Genomic Stress for Antitumor Immunity.

Antioxidants & redox signaling
2020-12-04 | Journal article
DOI: 10.1089/ars.2020.8221
PMID: 33143450
Contributors: min huang; Pu C; Tao S; Xu J; Huang M
Source: Self-asserted source
min huang

A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer.

Cell metabolism
2019-10-10 | Journal article
DOI: 10.1016/j.cmet.2019.09.014
PMID: 31607564
Contributors: min huang; Huang K; Liang Q; Zhou Y; Jiang LL; Gu WM; Luo MY; Tang YB; Wang Y; Lu W et al.
Source: Self-asserted source
min huang

EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells.

Acta pharmacologica Sinica
2019-07-17 | Journal article
DOI: 10.1038/s41401-019-0268-y
PMID: 31316177
PMC: PMC7471410
Contributors: min huang; Chen YH; Lv H; Shen N; Wang XM; Tang S; Xiong B; Ding J; Geng MY; Huang M
Source: Self-asserted source
min huang

Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer.

Nature communications
2019-06-20 | Journal article
DOI: 10.1038/s41467-019-10427-2
PMID: 31221965
PMC: PMC6586626
Contributors: min huang; Jin N; Bi A; Lan X; Xu J; Wang X; Liu Y; Wang T; Tang S; Zeng H et al.
Source: Self-asserted source
min huang

Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.

Cell
2018-09-13 | Journal article
DOI: 10.1016/j.cell.2018.08.058
PMID: 30220457
Contributors: min huang; Huang X; Yan J; Zhang M; Wang Y; Chen Y; Fu X; Wei R; Zheng XL; Liu Z et al.
Source: Self-asserted source
min huang

Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy.

Acta pharmaceutica Sinica. B
2018-02-16 | Journal article
DOI: 10.1016/j.apsb.2018.01.008
PMID: 30109180
PMC: PMC6089851
Contributors: min huang; Liu F; Yang X; Geng M; Huang M
Source: Self-asserted source
min huang
grade
Preferred source (of 2)‎

Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells.

The Journal of cell biology
2017-01-25 | Journal article | Author
DOI: 10.1083/jcb.201607008
PMID: 28122957
PMC: PMC5294784
Contributors: Qu J; Sun W; Zhong J; Lv H; Zhu M; Xu J; Jin N; zuoquan xie; Tan M; Shuhai Lin et al.
Source: Self-asserted source
min huang

Design and discovery of new pyrimidine coupled nitrogen aromatic rings as chelating groups of JMJD3 inhibitors

Bioorganic and Medicinal Chemistry Letters
2016 | Journal article
DOI: 10.1016/j.bmcl.2016.01.006
EID:

2-s2.0-84979195057
Contributors: Hu, J.; Wang, X.; Chen, L.; Huang, M.; Tang, W.; Zuo, J.; Liu, Y.-C.; Shi, Z.; Liu, R.; Shen, J. et al.
Source: Self-asserted source
min huang via Scopus - Elsevier

Discovery and structure activity relationship study of novel indazole amide inhibitors for extracellular signal-regulated kinase1/2 (ERK1/2)

Bioorganic and Medicinal Chemistry Letters
2016 | Journal article
DOI: 10.1016/j.bmcl.2016.04.029
EID:

2-s2.0-84963815452
Contributors: Li, L.; Liu, F.; Jin, N.; Tang, S.; Chen, Z.; Yang, X.; Ding, J.; Geng, M.; Jiang, L.; Huang, M. et al.
Source: Self-asserted source
min huang via Scopus - Elsevier

Exploiting histone deacetylases for cancer therapy: from hematological malignancies to solid tumors

Science China Life Sciences
2016 | Journal article
DOI: 10.1007/s11427-016-0300-y
EID:

2-s2.0-84997327223
Contributors: Huang, M.; Geng, M.
Source: Self-asserted source
min huang via Scopus - Elsevier

Feedback Activation of Leukemia Inhibitory Factor Receptor Limits Response to Histone Deacetylase Inhibitors in Breast Cancer

Cancer Cell
2016 | Journal article
DOI: 10.1016/j.ccell.2016.08.001
EID:

2-s2.0-84995545740
Contributors: Zeng, H.; Qu, J.; Jin, N.; Xu, J.; Lin, C.; Chen, Y.; Yang, X.; He, X.; Tang, S.; Lan, X. et al.
Source: Self-asserted source
min huang via Scopus - Elsevier

One-pot: N -glycosylation remodeling of IgG with non-natural sialylglycopeptides enables glycosite-specific and dual-payload antibody-drug conjugates

Organic and Biomolecular Chemistry
2016 | Journal article
DOI: 10.1039/c6ob01751g
EID:

2-s2.0-84991497860
Contributors: Tang, F.; Yang, Y.; Tang, Y.; Tang, S.; Yang, L.; Sun, B.; Jiang, B.; Dong, J.; Liu, H.; Huang, M. et al.
Source: Self-asserted source
min huang via Scopus - Elsevier

Acetylation at lysine 71 inactivates superoxide dismutase 1 and sensitizes cancer cells to genotoxic agents

Oncotarget
2015 | Journal article
EID:

2-s2.0-84940205973
Contributors: Lin, C.; Zeng, H.; Lu, J.; Xie, Z.; Sun, W.; Luo, C.; Ding, J.; Yuan, S.; Geng, M.; Huang, M.
Source: Self-asserted source
min huang via Scopus - Elsevier

C-Myc alterations confer therapeutic response and acquired resistance to c-Met inhibitors in MET-addicted cancers

Cancer Research
2015 | Journal article
DOI: 10.1158/0008-5472.CAN-14-2743
EID:

2-s2.0-84946600656
Contributors: Shen, A.; Wang, L.; Huang, M.; Sun, J.; Chen, Y.; Shen, Y.-Y.; Yang, X.; Wang, X.; Ding, J.; Geng, M.
Source: Self-asserted source
min huang via Scopus - Elsevier

JX06 selectively inhibits pyruvate dehydrogenase kinase PDK1 by a covalent cysteine modification

Cancer Research
2015 | Journal article
DOI: 10.1158/0008-5472.CAN-15-1023
EID:

2-s2.0-84955277637
Contributors: Sun, W.; Xie, Z.; Liu, Y.; Zhao, D.; Wu, Z.; Zhang, D.; Lv, H.; Tang, S.; Jin, N.; Jiang, H. et al.
Source: Self-asserted source
min huang via Scopus - Elsevier

Lactate dehydrogenase B is associated with the response to neoadjuvant chemotherapy in oral squamous cell carcinoma

PLoS ONE
2015 | Journal article
DOI: 10.1371/journal.pone.0125976
EID:

2-s2.0-84929332835
Contributors: Sun, W.; Zhang, X.; Ding, X.; Li, H.; Geng, M.; Xie, Z.; Wu, H.; Huang, M.
Source: Self-asserted source
min huang via Scopus - Elsevier

Discovery and optimization of 4,5-diarylisoxazoles as potent dual inhibitors of pyruvate dehydrogenase kinase and heat shock protein 90

Journal of Medicinal Chemistry
2014 | Journal article
DOI: 10.1021/jm5010144
EID:

2-s2.0-84918509348
Contributors: Meng, T.; Zhang, D.; Xie, Z.; Yu, T.; Wu, S.; Wyder, L.; Regenass, U.; Hilpert, K.; Huang, M.; Geng, M. et al.
Source: Self-asserted source
min huang via Scopus - Elsevier

Small-Molecule inhibitors of usp1 target id1 degradation in leukemic cells

Molecular Cancer Therapeutics
2013 | Journal article
DOI: 10.1158/1535-7163.MCT-13-0103-T
EID:

2-s2.0-84890525480
Contributors: Mistry, H.; Hsieh, G.; Buhrlage, S.J.; Huang, M.; Park, E.; Cuny, G.D.; Galinsky, I.; Stone, R.M.; Gray, N.S.; D'Andrea, A.D. et al.
Source: Self-asserted source
min huang via Scopus - Elsevier

Molecularly targeted cancer therapy: some lessons from the past decade.

Trends in pharmacological sciences
2013-12-19 | Journal article
DOI: 10.1016/j.tips.2013.11.004
PMID: 24361003
Contributors: min huang; Huang M; Shen A; Ding J; Geng M
Source: Self-asserted source
min huang

Inhibition of the Nedd8 system sensitizes cells to DNA interstrand cross-linking agents

Molecular Cancer Research
2012 | Journal article
DOI: 10.1158/1541-7786.MCR-11-0497
EID:

2-s2.0-84863370346
Contributors: Kee, Y.; Huang, M.; Chang, S.; Moreau, L.A.; Park, E.; Smith, P.G.; D'Andrea, A.D.
Source: Self-asserted source
min huang via Scopus - Elsevier

Human MutS and FANCM complexes function as redundant DNA damage sensors in the Fanconi Anemia pathway

DNA Repair
2011 | Journal article
DOI: 10.1016/j.dnarep.2011.09.006
EID:

2-s2.0-82555188036
Contributors: Huang, M.; Kennedy, R.; Ali, A.M.; Moreau, L.A.; Meetei, A.R.; D'Andrea, A.D.; Chen, C.C.
Source: Self-asserted source
min huang via Scopus - Elsevier

A new nuclease member of the FAN club

Nature Structural and Molecular Biology
2010 | Journal article
DOI: 10.1038/nsmb0810-926
EID:

2-s2.0-77955356541
Contributors: Huang, M.; D'Andrea, A.D.
Source: Self-asserted source
min huang via Scopus - Elsevier

The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response

Molecular Cell
2010 | Journal article
DOI: 10.1016/j.molcel.2010.07.005
EID:

2-s2.0-77955505023
Contributors: Huang, M.; Kim, J.M.; Shiotani, B.; Yang, K.; Zou, L.; D'Andrea, A.D.
Source: Self-asserted source
min huang via Scopus - Elsevier

Inactivation of Murine Usp1 Results in Genomic Instability and a Fanconi Anemia Phenotype

Developmental Cell
2009 | Journal article
DOI: 10.1016/j.devcel.2009.01.001
EID:

2-s2.0-59649114341
Contributors: Kim, J.M.; Parmar, K.; Huang, M.; Weinstock, D.M.; Ruit, C.A.; Kutok, J.L.; D'Andrea, A.D.
Source: Self-asserted source
min huang via Scopus - Elsevier

Peer review (12 reviews for 9 publications/grants)

Review activity for Acta pharmaceutica sinica B. (2)
Review activity for Advanced science. (2)
Review activity for Bioorganic chemistry. (1)
Review activity for Cell discovery. (1)
Review activity for Cell reports. (1)
Review activity for Cell systems. (2)
Review activity for Free radical biology & medicine. (1)
Review activity for Heliyon. (1)
Review activity for Signal transduction and targeted therapy. (1)
How many people are using ORCID?