Personal information

Innate Immunity, Enteric Nervous System, Inflammation and Cancer, Optogenetics, Cancer Immunotherapy, Synthetic Immunology, Spatial Transcriptomics
United States

Biography

Integrate multi-omics to study inflammation in space and time.

Activities

Employment (1)

Broad Institute of MIT and Harvard: Cambridge, MA, US

2019-10-07 to present | Postdoctoral Associate (klarman cell observatory-Aviv Regev & Ramnik Xavier Lab)
Employment
Source: Self-asserted source
Peng Tan

Professional activities (2)

American Association of Immunologists: Md., Md., US

2017-01-01 to 2018-12-31
Membership
Source: Self-asserted source
Peng Tan

Biophysical Society: Rockville, Maryland, US

2015-01-01 to 2017-12-31
Membership
Source: Self-asserted source
Peng Tan

Funding (1)

Role of TET proteins in innate lymphoid cells and inflammatory bowel disease

2016-05 to present | Award
Crohn's and Colitis Foundation of America (NY, NY, US)
GRANT_NUMBER:

439523

Source: Self-asserted source
Peng Tan

Works (41)

Spatial atlas of the mouse central nervous system at molecular resolution.

Nature
2023-09 | Journal article
Contributors: Shi H; He Y; Zhou Y; Huang J; Maher K; Wang B; Tang Z; Luo S; Tan P; Wu M et al.
Source: Self-asserted source
Peng Tan via Europe PubMed Central

Biomimetic and bioinspired nano-platforms for cancer vaccine development.

Exploration (Beijing, China)
2023-04 | Journal article
Contributors: Feng C; Tan P; Nie G; Zhu M
Source: Self-asserted source
Peng Tan via Europe PubMed Central

Vangl2 suppresses NF-κB signaling and ameliorates sepsis by targeting p65 for NDP52-mediated autophagic degradation

2023-04 | Preprint
Contributors: Lu J; Zhang J; Jiang H; Hu Z; He L; Yang J; Xie Y; Wu D; Li H; Zeng K et al.
Source: Self-asserted source
Peng Tan via Europe PubMed Central

Optical control of protein delivery and partitioning in the nucleolus.

Nucleic Acids Research
2022-03-23 | Journal article
Source: Self-asserted source
Peng Tan

Identification of a STIM1 Splicing Variant that Promotes Glioblastoma Growth.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
2022-01-25 | Journal article
Source: Self-asserted source
Peng Tan
grade
Preferred source (of 2)‎

Optophysiology: Illuminating cell physiology with optogenetics.

Physiological Reviews
2022-01-24 | Journal article
Source: Self-asserted source
Peng Tan

Circularly permuted LOV2 as a modular photoswitch for optogenetic engineering.

Nature Chemical Biology
2021-05-06 | Journal article
Source: Self-asserted source
Peng Tan
grade
Preferred source (of 2)‎

Microbiota regulate innate immune signaling and protective immunity against cancer.

Cell Host & Microbe
2021-04-21 | Journal article
Source: Self-asserted source
Peng Tan
grade
Preferred source (of 2)‎

Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.

Nature Medicine
2021-03-02 | Journal article
Source: Self-asserted source
Peng Tan

Design of Smart Antibody Mimetics with Photosensitive Switches

Advanced Biology
2021-02-05 | Journal article
Part of ISSN: 2701-0198
Contributors: Lian He; Peng Tan; Yun Huang; Yubin Zhou
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
Preferred source (of 2)‎

Engineering of a bona fide light-operated calcium channel

Nature Communications
2021-01-11 | Journal article
Part of ISSN: 2041-1723
Contributors: Lian He; Liuqing Wang; Hongxiang Zeng; Peng Tan; Guolin Ma; Sisi Zheng; Yaxin Li; Lin Sun; Fei Dou; Stefan Siwko et al.
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
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Engineering Supramolecular Organizing Centers for Optogenetic Control of Innate Immune Responses

Advanced Biology
2020 | Journal article
Part of ISSN: 2701-0198
Contributors: Peng Tan; Lian He; Yubin Zhou
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
Preferred source (of 2)‎

Beclin 2 negatively regulates innate immune signaling and tumor development.

The Journal of Clinical Investigation
2020-08-31 | Journal article
Source: Self-asserted source
Peng Tan
grade
Preferred source (of 2)‎

Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells

Biorxiv
2020-04-20 | Preprint
Source: Self-asserted source
Peng Tan

Autophagy and Immune-Related Diseases.

Advances in Experimental Medicine and Biology
2019-11-16 | Journal article
Source: Self-asserted source
Peng Tan
grade
Preferred source (of 2)‎

Autophagy and Viral Infection.

Advances in Experimental Medicine and Biology
2019-11-16 | Journal article
Source: Self-asserted source
Peng Tan
grade
Preferred source (of 2)‎

Myeloid loss of Beclin 1 promotes PD-L1hi precursor B cell lymphoma development.

The Journal of Clinical Investigation
2019-10-28 | Journal article
Source: Self-asserted source
Peng Tan
grade
Preferred source (of 2)‎

Discovery of Small-Molecule Inhibitors of the HSP90-Calcineurin-NFAT Pathway against Glioblastoma

Cell Chemical Biology
2019-01 | Journal article
Part of ISSN: 2451-9456
Contributors: Zhenzhen Liu; Hongli Li; Lian He; Yu Xiang; Chengsen Tian; Can Li; Peng Tan; Ji Jing; Yanpin Tian; Lupei Du et al.
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
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TRIM59 deficiency curtails breast cancer metastasis through SQSTM1-selective autophagic degradation of PDCD10

Autophagy
2019-01 | Journal article
Part of ISSN: 1554-8627
Contributors: Peng Tan; Lian He; Yubin Zhou
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
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Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks

Nature Communications
2018 | Journal article
Part of ISSN: 2041-1723
Contributors: Ang Li; Jung-Hwa Cho; Brian Reid; Chun-Chih Tseng; Lian He; Peng Tan; Chao-Yuan Yeh; Ping Wu; Yuwei Li; Randall B. Widelitz et al.
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
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Engineered Cross-Linking to Study the Pore Architecture of the CRAC Channel

The CRAC Channel
2018 | Other
Part of ISBN: 9781493987023
Part of ISSN: 1064-3745
Contributors: Guolin Ma; Lian He; Ji Jing; Peng Tan; Yun Huang; Yubin Zhou
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
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Inflammasome activation negatively regulates MyD88-IRF7 type I IFN signaling and anti-malaria immunity

Nature Communications
2018-11 | Journal article
Part of ISSN: 2041-1723
Contributors: Xiao Yu; Yang Du; Chunmei Cai; Baowei Cai; Motao Zhu; Changsheng Xing; Peng Tan; Meng Lin; Jian Wu; Jian Li et al.
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
Preferred source (of 2)‎

TRIM59 promotes breast cancer motility by suppressing p62-selective autophagic degradation of PDCD10

PLOS Biology
2018-11-08 | Journal article
Part of ISSN: 1545-7885
Contributors: Peng Tan; Youqiong Ye; Lian He; Jiansheng Xie; Ji Jing; Guolin Ma; Hongming Pan; Leng Han; Weidong Han; Yubin Zhou et al.
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
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p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance

Oncogene
2018-11-02 | Journal article
Part of ISSN: 0950-9232
Contributors: Jixiang Zhang; Peng Tan; Lei Guo; Jing Gong; Jingjing Ma; Jia Li; Minjung Lee; Shaohai Fang; Ji Jing; Gavin Johnson et al.
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
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Mutual Stabilization between TRIM9 Short Isoform and MKK6 Potentiates p38 Signaling to Synergistically Suppress Glioblastoma Progression

Cell Reports
2018-04 | Journal article
Part of ISSN: 2211-1247
Contributors: Kunpeng Liu; Chuanxia Zhang; Bowen Li; Weihong Xie; Jindong Zhang; Xichen Nie; Peng Tan; Limin Zheng; Song Wu; Yunfei Qin et al.
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
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DHX29 functions as an RNA co-sensor for MDA5-mediated EMCV-specific antiviral immunity

PLOS Pathogens
2018-02 | Journal article
Part of ISSN: 1553-7374
Contributors: Qingyuan Zhu; Peng Tan; Yinyin Li; Meng Lin; Chaoran Li; Jingrong Mao; Jun Cui; Wei Zhao; Helen Y. Wang; Rong-Fu Wang et al.
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
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Tgfbr2 inactivation facilitates cellular plasticity and development of Pten-null prostate cancer

Journal of Molecular Cell Biology
2018-01 | Journal article
Part of ISSN: 1759-4685
Contributors: Wei Zhao; Qingyuan Zhu; Peng Tan; Adebusola Ajibade; Teng Long; Wenyong Long; Qingtian Li; Pinghua Liu; Bo Ning; Helen Y Wang et al.
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
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Optical control of membrane tethering and interorganellar communication at nanoscales

Chemical Science
2017 | Journal article
Part of ISSN: 2041-6520
Contributors: Lian He; Ji Jing; Lei Zhu; Peng Tan; Guolin Ma; Qian Zhang; Nhung T. Nguyen; Junfeng Wang; Yubin Zhou; Yun Huang
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
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Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling

Molecular Cell
2017-10 | Journal article
Part of ISSN: 1097-2765
Contributors: Peng Tan; Lian He; Jun Cui; Chen Qian; Xin Cao; Meng Lin; Qingyuan Zhu; Yinyin Li; Changsheng Xing; Xiao Yu et al.
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
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Leucine-rich repeat–containing G protein–coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial–mesenchymal transition

Journal of Biological Chemistry
2017-08-02 | Journal article
Part of ISSN: 0021-9258
Contributors: Weijia Luo; Peng Tan; Melissa Rodriguez; Lian He; Kunrong Tan; Li Zeng; Stefan Siwko; Mingyao Liu
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
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Optogenetic Immunomodulation: Shedding Light on Antitumor Immunity

Trends in Biotechnology
2017-03 | Journal article
Part of ISSN: 0167-7799
Contributors: Peng Tan; Lian He; Gang Han; Yubin Zhou
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
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Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality

Immunity
2016-11 | Journal article
Part of ISSN: 1074-7613
Contributors: Xiao Yu; Baowei Cai; Mingjun Wang; Peng Tan; Xilai Ding; Jian Wu; Jian Li; Qingtian Li; Pinghua Liu; Changsheng Xing et al.
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
Preferred source (of 2)‎

TRIM14 Inhibits cGAS Degradation Mediated by Selective Autophagy Receptor p62 to Promote Innate Immune Responses

Molecular Cell
2016-10 | Journal article
Part of ISSN: 1097-2765
Contributors: Meixin Chen; Qingcai Meng; Yunfei Qin; Puping Liang; Peng Tan; Lian He; Yubin Zhou; Yongjun Chen; Junjiu Huang; Rong-Fu Wang et al.
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
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USP38 Inhibits Type I Interferon Signaling by Editing TBK1 Ubiquitination through NLRP4 Signalosome

Molecular Cell
2016-10 | Journal article
Part of ISSN: 1097-2765
Contributors: Meng Lin; Zhiyao Zhao; Zhifen Yang; Qingcai Meng; Peng Tan; Weihong Xie; Yunfei Qin; Rong-Fu Wang; Jun Cui
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
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Near-infrared photoactivatable control of Ca2+ signaling and optogenetic immunomodulation

eLife
2015 | Journal article
Part of ISSN: 2050-084X
Contributors: Lian He; Yuanwei Zhang; Guolin Ma; Peng Tan; Zhanjun Li; Shengbing Zang; Xiang Wu; Ji Jing; Shaohai Fang; Lijuan Zhou et al.
Source: Self-asserted source
Peng Tan via Crossref Metadata Search

Proteomic mapping of ER–PM junctions identifies STIMATE as a regulator of Ca2+ influx

Nature Cell Biology
2015-08 | Journal article
Part of ISSN: 1465-7392
Contributors: Ji Jing; Lian He; Aomin Sun; Ariel Quintana; Yuehe Ding; Guolin Ma; Peng Tan; Xiaowen Liang; Xiaolu Zheng; Liangyi Chen et al.
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
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Inside-out Ca2+ signalling prompted by STIM1 conformational switch

Nature Communications
2015-07 | Journal article
Part of ISSN: 2041-1723
Contributors: Guolin Ma; Ming Wei; Lian He; Chongxu Liu; Bo Wu; Shenyuan L. Zhang; Ji Jing; Xiaowen Liang; Alessandro Senes; Peng Tan et al.
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
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Proteomic mapping of ER-PM junctions in living HEK293 cells

Protocol Exchange
2015-07 | Journal article
Part of ISSN: 2043-0116
Contributors: YUBIN ZHOU; Lian He; Yue-He Ding; Peng Tan; Ji Jing; Meng-Qiu Dong; YUBIN ZHOU
Source: Self-asserted source
Peng Tan via Crossref Metadata Search

USP3 inhibits type I interferon signaling by deubiquitinating RIG-I-like receptors

Cell Research
2013 | Journal article
Part of ISSN: 1001-0602
Contributors: Jun Cui; Yanxia Song; Yinyin Li; Qingyuan Zhu; Peng Tan; Yunfei Qin; Helen Y Wang; Rong-Fu Wang
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
grade
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Overexpression of nuclear distribution protein (hNUDC) causes pro-apoptosis and differentiation in Dami megakaryocytes

Cell Proliferation
2013-09 | Journal article
Part of ISSN: 0960-7722
Contributors: Y. Xiao; Y. Zheng; P. Tan; P. Xu; Q. Zhang
Source: Self-asserted source
Peng Tan via Crossref Metadata Search

Live-Cell Visualization of Intracellular Interaction between a Nuclear Migration Protein (hNUDC) and the Thrombopoietin Receptor (Mpl)

PLoS ONE
2012 | Journal article
Part of ISSN: 1932-6203
Contributors: Yuan-Bin Zheng; Ying-Ying Xiao; Peng Tan; Qing Zhang; Peilin Xu; Ross Frederick Waller
Source: Self-asserted source
Peng Tan via Crossref Metadata Search
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