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Loop profile: 2328407

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Canada

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Employment (2)

University of Regina: Regina, CA

2019-01 to present | Visiting Professor (Biochemistry)
Employment
Source: Self-asserted source
Khaled A. Aly

Sinai University: El-Arish, EG

2013-09-01 to present | Faculty Member (on leave) (Microbiology and Immunology)
Employment
Source: Self-asserted source
Khaled A. Aly

Education and qualifications (3)

The University of Chicago: Chicago, IL, US

2011-06-01 to 2013-07-31 | Postdoctoral Scientist (Microbiology)
Education
Source: Self-asserted source
Khaled A. Aly

University of Wisconsin Madison: Madison, WI, US

2009-01-06 to 2011-05-31 | Research Associate (Bacteriology)
Education
Source: Self-asserted source
Khaled A. Aly

McMaster University: Hamilton, ON, CA

2003-01-06 to 2010-06-10 | Ph.D. (Biology)
Education
Source: Self-asserted source
Khaled A. Aly

Professional activities (3)

Frontiers in Genetics: Lausanne, CH

Editor
Invited position
Source: Self-asserted source
Khaled A. Aly

BMC Microbiology: London, GB

Reviewer
Invited position
Source: Self-asserted source
Khaled A. Aly

American Society for Microbiology: Washington, DC, US

Membership
Source: Self-asserted source
Khaled A. Aly

Works (23)

Sanitation Enzymes: Exquisite Surveillance of the Noncanonical Nucleotide Pool to Safeguard the Genetic Blueprint

Seminars in Cancer Biology
2023-05 | Journal article
DOI: 10.1016/j.semcancer.2023.05.005
Part of ISSN: 1044-579X
Contributors: Kirsten Broderick; Mohamed Taha Moutaoufik; Khaled A. Aly; Mohan Babu
Source: Self-asserted source
Khaled A. Aly

Insights into SACS pathological attributes in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS)☆

Current Opinion in Chemical Biology
2022-12 | Journal article
DOI: 10.1016/j.cbpa.2022.102211
Part of ISSN: 1367-5931
Contributors: Khaled A. Aly
Source: Self-asserted source
Khaled A. Aly

Auxotrophic and prototrophic conditional genetic networks reveal the rewiring of transcription factors in Escherichia coli.

Nature communications
2022-07-14 | Journal article
DOI: 10.1038/s41467-022-31819-x
PMID: 35835781
Source: Self-asserted source
Khaled A. Aly

A computational approach to rapidly design peptides that detect SARS-CoV-2 surface protein S

NAR Genomics and Bioinformatics
2022-07-09 | Journal article
DOI: 10.1093/nargab/lqac058
Part of ISSN: 2631-9268
Contributors: Khaled A. Aly
Source: Self-asserted source
Khaled A. Aly

The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF

Nucleic Acids Research
2021-07-09 | Journal article
DOI: 10.1093/nar/gkab585
Part of ISSN: 0305-1048
Contributors: Matthew Jessulat; Shahreen Amin; Mohsen Hooshyar; Ramy Malty; Mohamed Taha Moutaoufik; Mara Zilocchi; Zoe Istace; Sadhna Phanse; Hiroyuki Aoki; Katayoun Omidi et al.
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

From Fuzziness to Precision Medicine: On the Rapidly Evolving Proteomics with Implications in Mitochondrial Connectivity to Rare Human Disease

iScience
2021-01 | Journal article
DOI: 10.1016/j.isci.2020.102030
Part of ISSN: 2589-0042
Contributors: Khaled A. Aly; Mohamed Taha Moutaoufik; Sadhna Phanse; Qingzhou Zhang; Mohan Babu
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

Mitochondria under the spotlight: On the implications of mitochondrial dysfunction and its connectivity to neuropsychiatric disorders

Computational and Structural Biotechnology Journal
2020 | Journal article
DOI: 10.1016/j.csbj.2020.09.008
Part of ISSN: 2001-0370
Contributors: Mara Zilocchi; Kirsten Broderick; Sadhna Phanse; Khaled A. Aly; Mohan Babu
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

HERG channel and cancer: A mechanistic review of carcinogenic processes and therapeutic potential

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
2020-04 | Journal article
DOI: 10.1016/j.bbcan.2020.188355
Part of ISSN: 0304-419X
Contributors: Siyi He; Mohamed Taha Moutaoufik; Saadul Islam; Amit Persad; Adam Wu; Khaled A. Aly; Humphrey Fonge; Mohan Babu; Francisco S. Cayabyab
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

Misconnecting the dots: altered mitochondrial protein-protein interactions and their role in neurodegenerative disorders

Expert Review of Proteomics
2020-01-28 | Journal article
DOI: 10.1080/14789450.2020.1723419
Part of ISSN: 1478-9450
Part of ISSN: 1744-8387
Source: Self-asserted source
Khaled A. Aly

A Gaussian process-based definition reveals new and bona fide genetic interactions compared to a multiplicative model in the Gram-negative Escherichia coli

Bioinformatics
2019-08 | Journal article
DOI: 10.1093/bioinformatics/btz673
Part of ISSN: 1367-4803
Contributors: Ashwani Kumar; Ali Hosseinnia; Alla Gagarinova; Sadhna Phanse; Sunyoung Kim; Khaled A Aly; Sandra Zilles; Mohan Babu; Jonathan Wren
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

The transmembrane domain of the Staphylococcus aureus ESAT-6 component EssB mediates interaction with the integral membrane protein EsaA, facilitating partially regulated secretion in a heterologous host

Archives of Microbiology
2018-05-08 | Journal article
DOI: 10.1007/s00203-018-1519-x
Part of ISSN: 0302-8933
Contributors: Manar M. Ahmed; Khaled M. Aboshanab; Yasser M. Ragab; Dominique M. Missiakas; Khaled A. Aly
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

The C-terminus of the ESAT6-like secretion system virulence factor EsxC mediates divalent cation-dependent homodimerization

Toxicon
2018-03 | Journal article
DOI: 10.1016/j.toxicon.2018.02.047
Part of ISSN: 0041-0101
Contributors: Rofida M. Abd El-Fatah; Noha M. Mesbah; Dina M. Abo-Elmatty; Khaled A. Aly
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

Error-prone PCR mutagenesis and reverse bacterial two-hybrid screening identify a mutation in asparagine 53 of the Staphylococcus aureus ESAT6-like component EsxB that perturbs interaction with EsxD

Folia Microbiologica
2018-02 | Journal article
DOI: 10.1007/s12223-018-0591-6
Part of ISSN: 0015-5632
Contributors: Amany M. Ibrahim; Yasser M. Ragab; Khaled A. Aly; Mohamed A. Ramadan
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

Isolation of a Membrane Protein Complex for Type VII Secretion in Staphylococcus aureus

Journal of Bacteriology
2017-09-05 | Journal article
DOI: 10.1128/jb.00482-17
Part of ISSN: 0021-9193
Contributors: Khaled A. Aly; Mark Anderson; Ryan Jay Ohr; Dominique Missiakas; Thomas J. Silhavy
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

Quorum sensing signal production by sponge-associated bacteria isolated from the Red Sea, Egypt

African Journal of Biotechnology
2017-08-09 | Journal article
DOI: 10.5897/ajb2017.16078
Part of ISSN: 1684-5315
Contributors: Yahia Ramadan; Hanora Amro; Fahmy Nora; A. Aly Khaled
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

EssE Promotes Staphylococcus aureus ESS-Dependent Protein Secretion To Modify Host Immune Responses during Infection

Journal of Bacteriology
2016-10 | Journal article
DOI: 10.1128/jb.00527-16
Part of ISSN: 0021-9193
Contributors: Mark Anderson; Ryan Jay Ohr; Khaled A. Aly; Salvatore Nocadello; Hwan K. Kim; Chloe E. Schneewind; Olaf Schneewind; Dominique Missiakas; Thomas J. Silhavy
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

Secretion of atypical protein substrates by the ESAT-6 Secretion System ofStaphylococcus aureus

Molecular Microbiology
2013-10-04 | Journal article
DOI: 10.1111/mmi.12395
Part of ISSN: 0950-382X
Contributors: Mark Anderson; Khaled A. Aly; Yi-Hsing Chen; Dominique Missiakas
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

Cell-free production of integral membrane aspartic acid proteases reveals zinc-dependent methyltransferase activity of thePseudomonas aeruginosaprepilin peptidase PilD

MicrobiologyOpen
2012 | Journal article
DOI: 10.1002/mbo3.51
Part of ISSN: 2045-8827
Contributors: Khaled A. Aly; Emily T. Beebe; Chi H. Chan; Michael A. Goren; Carolina Sepúlveda; Shin-ichi Makino; Brian G. Fox; Katrina T. Forest
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

The Type IV Secretion System Component VirB5 Binds to the trans-Zeatin Biosynthetic Enzyme Tzs and Enables Its Translocation to the Cell Surface of Agrobacterium tumefaciens

Journal of Bacteriology
2007 | Journal article
DOI: 10.1128/jb.01718-07
Part of ISSN: 0021-9193
Contributors: K. A. Aly; L. Krall; F. Lottspeich; C. Baron
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

The VirB5 protein localizes to the T-pilus tips in Agrobacterium tumefaciens

Microbiology
2007-11-01 | Journal article
DOI: 10.1099/mic.0.2007/010462-0
Part of ISSN: 1350-0872
Contributors: K. A. Aly; C. Baron
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

The Brucella suis Type IV Secretion System Assembles in the Cell Envelope of the Heterologous Host Agrobacterium tumefaciens and Increases IncQ Plasmid pLS1 Recipient Competence

Infection and Immunity
2005 | Journal article
DOI: 10.1128/iai.74.1.108-117.2006
Part of ISSN: 0019-9567
Contributors: A. Carle; C. Hoppner; K. Ahmed Aly; Q. Yuan; A. den Dulk-Ras; A. Vergunst; D. O'Callaghan; C. Baron
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

Identification of the VirB4-VirB8-VirB5-VirB2 Pilus Assembly Sequence of Type IV Secretion Systems

Journal of Biological Chemistry
2005-05 | Journal article
DOI: 10.1074/jbc.m502347200
Part of ISSN: 0021-9258
Contributors: Qing Yuan; Anna Carle; Chan Gao; Durga Sivanesan; Khaled Ahmed Aly; Christoph Höppner; Lilian Krall; Natalie Domke; Christian Baron
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

Co-fractionation–mass spectrometry to characterize native mitochondrial protein assemblies in mammalian neurons and brain

Nature Protocols
Journal article
DOI: 10.1038/s41596-023-00901-z
Source: Self-asserted source
Khaled A. Aly via Crossref Metadata Search

Peer review (1 review for 1 publication/grant)

Review activity for BMC microbiology (1)
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