Personal information

United States

Activities

Employment (4)

University of Washington: Seattle, WA, US

2005-09-20 to present | Research Scientist in Lab of Pradeep Singh (Microbiology)
Employment
Source: Self-asserted source
Richard Siehnel

Elitra Pharmaceuticals: San Diego, CA, US

2003-01-05 to 2004-05-01 | Principle Scientist (Anti-Infectives)
Employment
Source: Self-asserted source
Richard Siehnel

Procter & Gamble Pharmaceuticals: Cincinnati, OH, US

1993-08-01 to 2003-01-04 | Sr. Research Scientist (Anti-Infectives)
Employment
Source: Self-asserted source
Richard Siehnel

University of British Columbia: Vancouver, BC, CA

1986-01-01 to 1993-07-24 | Research Scientist in lab of R.E.W. Hancock (Microbiology)
Employment
Source: Self-asserted source
Richard Siehnel

Education and qualifications (2)

University at Buffalo - The State University of New York: Buffalo, NY, US

1979-09-26 to 1985-09-01 | Ph.D. (Cell & Molecular Biology)
Education
Source: Self-asserted source
Richard Siehnel

Western Washington University: Bellingham, WA, US

1975-09-27 to 1978-06-02 | B.Sc. (Chemistry/Biology)
Education
Source: Self-asserted source
Richard Siehnel

Works (27)

Bacterial fitness in chronic wounds appears to be mediated by the capacity for high-density growth, not virulence or biofilm functions

PLOS Pathogens
2019-03-20 | Journal article
Contributors: Sarah J. Morgan; Simon L. Dove; Soyeon I. Lippman; Gilbert E. Bautista; Joe J. Harrison; Christopher L. Harding; Larry A. Gallagher; Ann-Chee Cheng; Richard Siehnel; Sumedha Ravishankar et al.
Source: check_circle
Crossref

Determinants of extreme β-lactam tolerance in the Burkholderia pseudomallei complex

Antimicrobial Agents and Chemotherapy
2018 | Journal article
EID:

2-s2.0-85044517895

Contributors: Held, K.; Gasper, J.; Morgan, S.; Siehnel, R.; Singh, P.; Manoil, C.
Source: Self-asserted source
Richard Siehnel via Scopus - Elsevier

Gallium disrupts bacterial iron metabolism and has therapeutic effects in mice and humans with lung infections

Science Translational Medicine
2018 | Journal article
EID:

2-s2.0-85054057700

Contributors: Goss, C.H.; Kaneko, Y.; Khuu, L.; Anderson, G.D.; Ravishankar, S.; Aitken, M.L.; Lechtzin, N.; Zhou, G.; Czyz, D.M.; McLean, K. et al.
Source: Self-asserted source
Richard Siehnel via Scopus - Elsevier

Precision-engineering the Pseudomonas aeruginosa genome with two-step allelic exchange.

Nature protocols
2015-11 | Journal article
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Probing the protein interaction network of Pseudomonas aeruginosa cells by chemical cross-linking mass spectrometry.

Structure (London, England : 1993)
2015-04 | Journal article
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteria.

Science (New York, N.Y.)
2011-11 | Journal article
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

A unique regulator controls the activation threshold of quorum-regulated genes in Pseudomonas aeruginosa.

Proceedings of the National Academy of Sciences of the United States of America
2010-04 | Journal article
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.

Proteins
2007-02 | Journal article
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Development and validation of a whole-cell inhibition assay for bacterial methionine aminopeptidase by surface-enhanced laser desorption ionization-time of flight mass spectrometry.

Antimicrobial agents and chemotherapy
2005-08 | Journal article
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Preparation and antimicrobial assessment of 2-thioether-linked quinolonyl-carbapenems

Journal of Antibiotics
1998 | Journal article
EID:

2-s2.0-15644376844

Contributors: Hershberger, P.M.; Switzer, A.G.; Yelm, K.E.; Coleman, M.C.; Devries, C.A.; Rourke, F.J.; Davis, B.W.; Kraft, W.G.; Twinem, T.L.; Koenigs, P.M. et al.
Source: Self-asserted source
Richard Siehnel via Scopus - Elsevier

Quinolone efflux protein nora is a proton-driven drug pump

FASEB Journal
1997 | Journal article
EID:

2-s2.0-33750106248

Contributors: Grinius, L.L.; Siehnel, R.J.; Morris, C.M.
Source: Self-asserted source
Richard Siehnel via Scopus - Elsevier

Physical mapping of 32 genetic markers on the Pseudomonas aeruginosa PAO1 chromosome.

Microbiology (Reading, England)
1996-01 | Journal article
PMID: 8581173
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Analysis of two gene regions involved in the expression of the imipenem-specific, outer membrane porin protein OprD of Pseudomonas aeruginosa.

FEMS microbiology letters
1992-10 | Journal article
PMID: 1427017
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Analysis of the Pseudomonas aeruginosa major outer membrane protein OprF by use of truncated OprF derivatives and monoclonal antibodies.

Journal of bacteriology
1992-08 | Journal article
PMID: 1378429
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Polyphosphate-selective porin OprO of Pseudomonas aeruginosa: expression, purification and sequence.

Molecular microbiology
1992-08 | Journal article
PMID: 1406271
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Reevaluation, using intact cells, of the exclusion limit and role of porin OprF in Pseudomonas aeruginosa outer membrane permeability.

Journal of bacteriology
1992-08 | Journal article
PMID: 1322882
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Overexpression in Escherichia coli and functional analysis of a novel PPi-selective porin, oprO, from Pseudomonas aeruginosa.

Journal of bacteriology
1992-01 | Journal article
PMID: 1370289
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Conservation of the gene for outer membrane protein OprF in the family Pseudomonadaceae: sequence of the Pseudomonas syringae oprF gene.

Journal of bacteriology
1991-01 | Journal article
PMID: 1898935
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Outer membrane proteins of Pseudomonas.

Molecular microbiology
1990-07 | Journal article
PMID: 1700255
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Sequence and relatedness in other bacteria of the Pseudomonas aeruginosa oprP gene coding for the phosphate-specific porin P.

Molecular microbiology
1990-05 | Journal article
PMID: 1697017
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Gene cloning and expression of the Pseudomonas aeruginosa periplasmic phosphate-binding protein

FEMS Microbiology Letters
1988 | Journal article
EID:

2-s2.0-0023774276

Contributors: Worobec, E.A.; Siehnel, R.J.; Gladman, P.; Hancock, R.E.W.
Source: Self-asserted source
Richard Siehnel via Scopus - Elsevier

Cloning of the Pseudomonas aeruginosa outer membrane porin protein P gene: evidence for a linked region of DNA homology.

Journal of bacteriology
1988-05 | Journal article
PMID: 2834340
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Regulation of components of the Pseudomonas aeruginosa phosphate-starvation-inducible regulon in Escherichia coli.

Molecular microbiology
1988-05 | Journal article
PMID: 2456446
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central
grade
Preferred source (of 2)‎

Unbalanced rRNA gene dosage and its effects on rRNA and ribosomal-protein synthesis

Journal of Bacteriology
1985 | Journal article
EID:

2-s2.0-0021847911

Contributors: Siehnel, R.J.; Morgan, E.A.
Source: Self-asserted source
Richard Siehnel via Scopus - Elsevier

Unbalanced rRNA gene dosage and its effects on rRNA and ribosomal-protein synthesis.

Journal of bacteriology
1985-08 | Journal article
PMID: 3894326
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central

Efficient read-through of Tn9 and IS1 by RNA polymerase molecules that initiate at rRNA promoters

Journal of Bacteriology
1983 | Journal article
EID:

2-s2.0-0020662504

Contributors: Siehnel, R.J.; Morgan, E.A.
Source: Self-asserted source
Richard Siehnel via Scopus - Elsevier

Efficient read-through of Tn9 and IS1 by RNA polymerase molecules that initiate at rRNA promoters.

Journal of bacteriology
1983-02 | Journal article
PMID: 6185465
Source: Self-asserted source
Richard Siehnel via Europe PubMed Central