Personal information

Emails & domains

Verified email domains

Websites & social links

Google Scholar Profile
My Bibliography - NCBI

Other IDs

Scopus Author ID: 57218882068

Keywords

Cancer research, Radiation, Immunology, Tumor microenvironment, Tumor immunology, Pathology, DNA damage

Countries

United States

Biography

I am a Postdoctoral Fellow in the Department of Radiation Physics at The University of Texas MD Anderson Cancer Center, where my research focuses on improving radiotherapy by targeting DNA repair deficiencies. My background encompasses experimental and molecular pathology, biochemistry, and toxicology. Currently, I am investigating how combining photon and proton radiation with DNA polymerase theta inhibitors can enhance radiosensitization and stimulate an immune response. Additionally, I am exploring the potential of combining immune checkpoint inhibitors with DNA polymerase theta inhibitors and radiation to address significant challenges in radiation research, specifically in overcoming resistance to both radiotherapy and immunotherapy.

Activities

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Employment (3)

The University of Texas MD Anderson Cancer Center: Houston, US

2024-04-15 to present | Postdoctoral Fellow (Radiation Physics)
Employment
Source: Self-asserted source
Walison Augusto da Silva Brito

Universidade Estadual de Londrina: Londrina, BR

2020-04-01 to 2023-12-08 | Doutorando (Departamento de Ciências Patológicas)
Employment
Source: Self-asserted source
Walison Augusto da Silva Brito

Leibniz Institute fur Plasma Science and Technology (INP): Greifswald, DE

2020-10-04 to 2023-06-30 | PhD student (ZIK plasmatis 'Plasma-Redox-Effects')
Employment
Source: Self-asserted source
Walison Augusto da Silva Brito

Education and qualifications (3)

Universidade Estadual de Londrina: Londrina, BR

2020-03-01 to 2023-12-08 | Doctor in Experimental Pathology
Education
Source: Self-asserted source
Walison Augusto da Silva Brito

Universidade Estadual de Londrina: Londrina, BR

2018-03-01 to 2020-03-31 | Master in Experimental Pathology
Education
Source: Self-asserted source
Walison Augusto da Silva Brito

Universidade Estadual de Londrina: Londrina, BR

2014-03-01 to 2017-12-21 | Bachelor in Biomedicine
Education
Source: Self-asserted source
Walison Augusto da Silva Brito

Works (14)

Sonicated polyethylene terephthalate nano- and micro-plastic-induced inflammation, oxidative stress, and autophagy in vitro

Chemosphere
2024-05 | Journal article
DOI: 10.1016/j.chemosphere.2024.141813
Contributors: Walison Augusto da Silva Brito; Mehdi Ravandeh; Fariba Saadati; Debora Singer; Anna Daniela Dorsch; Anke Schmidt; Alessandra Lourenço Cecchini; Kristian Wende; Sander Bekeschus
Source: check_circle
Crossref

Nanoplastic Size and Surface Chemistry Dictate Decoration by Human Saliva Proteins

ACS Applied Materials & Interfaces
2024-05-22 | Journal article
DOI: 10.1021/acsami.4c00014
Part of ISSN: 1944-8244
Part of ISSN: 1944-8252
Contributors: Anna Dorsch; Fritz Förschner; Mehdi Ravandeh; Walison Augusto da Silva Brito; Fariba Saadati; Mihaela Delcea; Kristian Wende; Sander Bekeschus
Source: Self-asserted source
Walison Augusto da Silva Brito

Comprehensive in vitro polymer type, concentration, and size correlation analysis to microplastic toxicity and inflammation

Science of the Total Environment
2023 | Journal article
DOI: 10.1016/j.scitotenv.2022.158731
EID:

2-s2.0-85138115294

Part of ISSN: 18791026 00489697
Contributors: da Silva Brito, W.A.; Singer, D.; Miebach, L.; Saadati, F.; Wende, K.; Schmidt, A.; Bekeschus, S.
Source: Self-asserted source
Walison Augusto da Silva Brito via Scopus - Elsevier

Lipid Corona Formation on Micro- and Nanoplastic Particles Modulates Uptake and Toxicity in A549 Cells

Materials
2023-07-19 | Journal article
DOI: 10.3390/ma16145082
Part of ISSN: 1996-1944
Contributors: Anna Daniela Dorsch; Walison Augusto da Silva Brito; Mihaela Delcea; Kristian Wende; Sander Bekeschus
Source: Self-asserted source
Walison Augusto da Silva Brito

Antioxidant Defense in Primary Murine Lung Cells following Short- and Long-Term Exposure to Plastic Particles

Antioxidants
2023-01-18 | Journal article
DOI: 10.3390/antiox12020227
Part of ISSN: 2076-3921
Contributors: Anke Schmidt; Melissa Mühl; Walison Augusto da Silva Brito; Debora Singer; Sander Bekeschus
Source: Self-asserted source
Walison Augusto da Silva Brito

Short- and long-term polystyrene nano- and microplastic exposure promotes oxidative stress and divergently affects skin cell architecture and Wnt/beta-catenin signaling

Particle and Fibre Toxicology
2023-01-16 | Journal article
DOI: 10.1186/s12989-023-00513-1
Part of ISSN: 1743-8977
Contributors: Anke Schmidt; Walison Augusto da Silva Brito; Debora Singer; Melissa Mühl; Julia Berner; Fariba Saadati; Christina Wolff; Lea Miebach; Kristian Wende; Sander Bekeschus
Source: Self-asserted source
Walison Augusto da Silva Brito

Consequences of nano and microplastic exposure in rodent models: the known and unknown

Particle and Fibre Toxicology
2022 | Journal article
DOI: 10.1186/s12989-022-00473-y
EID:

2-s2.0-85128650219

Part of ISSN: 17438977
Contributors: da Silva Brito, W.A.; Mutter, F.; Wende, K.; Cecchini, A.L.; Schmidt, A.; Bekeschus, S.
Source: Self-asserted source
Walison Augusto da Silva Brito via Scopus - Elsevier

Creatine supplementation protects against diet-induced non-alcoholic fatty liver but exacerbates alcoholic fatty liver

Life Sciences
2022 | Journal article
DOI: 10.1016/j.lfs.2022.121064
EID:

2-s2.0-85139736759

Part of ISSN: 18790631 00243205
Contributors: Marinello, P.C.; Cella, P.S.; Testa, M.T.J.; Guirro, P.B.; da Silva Brito, W.A.; Padilha, C.S.; Cecchini, A.L.; da Silva, R.P.; Duarte, J.A.R.; Deminice, R.
Source: Self-asserted source
Walison Augusto da Silva Brito via Scopus - Elsevier

Role of papillary thyroid carcinoma patients with Hashimoto thyroiditis: evaluation of oxidative stress and inflammatory markers

Clinical and Translational Oncology
2022 | Journal article
DOI: 10.1007/s12094-022-02891-y
EID:

2-s2.0-85139888294

Part of ISSN: 16993055 1699048X
Contributors: Lopes, N.M.D.; Lens, H.H.M.; da Silva Brito, W.A.; Bianchi, J.K.; Marinello, P.C.; Cecchini, R.; Armani, A.; Cecchini, A.L.
Source: Self-asserted source
Walison Augusto da Silva Brito via Scopus - Elsevier

Optimized High-Content Imaging Screening Quantifying Micronuclei Formation in Polymer-Treated HaCaT Keratinocytes

Nanomaterials
2022-12-15 | Journal article
DOI: 10.3390/nano12244463
Contributors: Fariba Saadati; Walison Augusto da Silva Brito; Steffen Emmert; Sander Bekeschus
Source: check_circle
Crossref
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Metformin pretreatment reduces effect to dacarbazine and suppresses melanoma cell resistance

Cell Biology International
2022-01 | Journal article
DOI: 10.1002/cbin.11700
Contributors: Larissa J. Sanches; Poliana C. Marinello; Walison A. da Silva Brito; Natália M. D. Lopes; Rodrigo C. Luiz; Rubens Cecchini; Alessandra L. Cecchini
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

The anticancer efficacy of plasma-oxidized saline (Pos) in the ehrlich ascites carcinoma model in vitro and in vivo

Biomedicines
2021 | Journal article
DOI: 10.3390/biomedicines9080932
EID:

2-s2.0-85112638908

Part of ISSN: 22279059
Contributors: Brito, W.A.S.; Freund, E.; Nascimento, T.D.H.D.; Pasqual-Melo, G.; Sanches, L.J.; Dionísio, J.H.R.; Fumegali, W.C.; Miebach, L.; Cecchini, A.L.; Bekeschus, S.
Source: Self-asserted source
Walison Augusto da Silva Brito via Scopus - Elsevier

Patterns of cell death induced by metformin in human MCF-7 breast cancer cells

Pathology - Research and Practice
2020-11 | Journal article
DOI: 10.1016/j.prp.2020.153199
Part of ISSN: 0344-0338
Source: Self-asserted source
Walison Augusto da Silva Brito
grade
Preferred source (of 2)‎

Creatine supplementation exacerbates ethanol-induced hepatic damage in mice

Nutrition
2019-10 | Journal article
DOI: 10.1016/j.nut.2019.05.004
Part of ISSN: 0899-9007
Source: Self-asserted source
Walison Augusto da Silva Brito
grade
Preferred source (of 2)‎
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