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Continuous Pharmaceutical Manufacturing, Crystallization, Directed Self-Assembly, Dynamic Modeling, Process Design and Control
Hong Kong SAR China

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Employment (1)

Hong Kong University of Science and Technology: Hong Kong, HK

Assistant Professor, Dept of Chemical & Biomolecular Engineering
Employment
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Hong Kong University of Science and Technology

Works (50 of 63)

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Page 1 of 2

11-Azaartemisinin cocrystals with preserved lactam:acid heterosynthons

CrystEngComm
2018 | Journal article
EID:

2-s2.0-85042659702

Contributors: Nisar, M.; Sung, H.H.-Y.; Puschmann, H.; Lakerveld, R.; Haynes, R.K.; Williams, I.D.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

A review on recent technologies for the manufacture of pulmonary drugs

Therapeutic Delivery
2018 | Journal article
EID:

2-s2.0-85038393760

Contributors: Hadiwinoto, G.D.; Lip Kwok, P.C.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Control system implementation and plant-wide control of continuous pharmaceutical manufacturing pilot plant (end-to-end manufacturing process)

Computer Aided Chemical Engineering
2018 | Book
EID:

2-s2.0-85044633194

Contributors: Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Design, characterization and model validation of a LED-based photocatalytic reactor for gas phase applications

Chemical Engineering Journal
2018 | Journal article
EID:

2-s2.0-85040590729

Contributors: Khodadadian, F.; de Boer, M.W.; Poursaeidesfahani, A.; van Ommen, J.R.; Stankiewicz, A.I.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Electric-Field-Assisted Protein Crystallization in Continuous Flow

Crystal Growth and Design
2018 | Journal article
EID:

2-s2.0-85046464500

Contributors: Li, F.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Experimental validation of scheduled PID control for directed self-assembly of colloidal particles in microfluidic devices

Computer Aided Chemical Engineering
2018 | Book
EID:

2-s2.0-85050594594

Contributors: Gao, Y.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Feedback control for defect-free alignment of colloidal particles

Lab on a Chip
2018 | Journal article
EID:

2-s2.0-85049917496

Contributors: Gao, Y.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Integrated solvent and process design for continuous crystallization and solvent recycling using PC-SAFT

AIChE Journal
2018 | Journal article
EID:

2-s2.0-85042731506

Contributors: Wang, J.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Integrated Solvent and Process Optimization Using PC-SAFT for Continuous Crystallization with Energy-intensive Solvent Separation for Recycling

Computer Aided Chemical Engineering
2018 | Book
EID:

2-s2.0-85050628371

Contributors: Wang, J.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Process intensification for pharmaceutical crystallization

Chemical Engineering and Processing - Process Intensification
2018 | Journal article
EID:

2-s2.0-85044569280

Contributors: Wang, J.; Li, F.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

An optimization-based approach for structural design of self-assembled DNA tiles

AIChE Journal
2017 | Journal article
EID:

2-s2.0-85018971693

Contributors: Gao, Y.; Mi, Y.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Continuous Membrane-Assisted Crystallization to Increase the Attainable Product Quality of Pharmaceuticals and Design Space for Operation

Industrial and Engineering Chemistry Research
2017 | Journal article
EID:

2-s2.0-85020649166

Contributors: Wang, J.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Influence of Alternating Electric Fields on Protein Crystallization in Microfluidic Devices with Patterned Electrodes in a Parallel-Plate Configuration

Crystal Growth and Design
2017 | Journal article
EID:

2-s2.0-85020242694

Contributors: Li, F.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Model Predictive Control of an Integrated Continuous Pharmaceutical Manufacturing Pilot Plant

Organic Process Research and Development
2017 | Journal article
EID:

2-s2.0-85020854023

Contributors: Mesbah, A.; Paulson, J.A.; Lakerveld, R.; Braatz, R.D.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

An optimization-based approach for the design of self-assembled DNA tiles

Engineering Sciences and Fundamentals 2016 - Core Programming Area at the 2016 AIChE Annual Meeting
2016 | Conference paper
EID:

2-s2.0-85019120858

Contributors: Gao, Y.; Mi, Y.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Microwave Assisted Direct Nucleation Control for Batch Crystallization: Crystal Size Control with Reduced Batch Time

Crystal Growth and Design
2016 | Journal article
EID:

2-s2.0-84954056828

Contributors: Kacker, R.; Salvador, P.M.; Sturm, G.S.J.; Stefanidis, G.D.; Lakerveld, R.; Nagy, Z.K.; Kramer, H.J.M.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Model-Based Optimization of a Photocatalytic Reactor with Light-Emitting Diodes

Chemical Engineering and Technology
2016 | Journal article
EID:

2-s2.0-84988521714

Contributors: Khodadadian, F.; Poursaeidesfahani, A.; Li, Z.; van Ommen, J.R.; Stankiewicz, A.I.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Modelling and experimental validation of an annular LED-based photocatalytic reactor

22nd International Congress of Chemical and Process Engineering, CHISA 2016 and 19th Conference on Process Integration, Modelling and Optimisation for Energy Saving and Pollution Reduction, PRES 2016
2016 | Conference paper
EID:

2-s2.0-85050763694

Contributors: Khodadadian, F.; De Boer, M.; Van Ommen, J.R.; Stankiewicz, A.I.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Photocatalysis: Past achievements and future trends

RSC Green Chemistry
2016 | Book
EID:

2-s2.0-84986575808

Contributors: Khodadadian, F.; Nasalevich, M.; Kapteijn, F.; Stankiewicz, A.I.; Lakerveld, R.; Gascon, J.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Towards experimental validation of a multi-resolution approach for directed self-assembly of non-periodic structures:â spatial control of particle densities

Computing and Systems Technology Division 2016 - Core Programming Area at the 2016 AIChE Annual Meeting
2016 | Conference paper
EID:

2-s2.0-85019133507

Contributors: Gao, Y.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Controlled formation of nanostructures with desired geometries: Part 3. Dynamic modeling and simulation of directed self-assembly of nanoparticles through adaptive finite state projection

Industrial and Engineering Chemistry Research
2015 | Journal article
Contributors: Ramaswamy, Sivaraman; Lakerveld, Richard; Barton, Paul I.; Stephanopoulos, George
Source: check_circle
Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

Model-based Optimization of a LED-based photocatalytic reactor

Catalysis and Reaction Engineering Division 2015 - Core Programming Area at the 2015 AIChE Annual Meeting
2015 | Conference paper
EID:

2-s2.0-84971491645

Contributors: Khodadadian, F.; Li, Z.; Van Ommen, J.R.; Stankiewicz, A.; Lakerveld, R.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Plant-wide model predictive control for a continuous pharmaceutical process

2015 American Control Conference, Palmer House Hilton, Chicago, IL, USA
2015 | Conference paper
Part of ISBN: 9781479986842
Contributors: Mesbah, Ali; Paulson, Joel A.; Lakerveld, Richard; Braatz, Richard D.
Source: check_circle
Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

An Air-Lift Crystallizer Can Suppress Secondary Nucleation at a Higher Supersaturation Compared to a Stirred Crystallizer

Crystal growth & design
2014 | Journal article
Contributors: Lakerveld, Richard; Van Krochten, Jeroen J. H.; Kramer, Herman J. M.
Source: check_circle
Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

Application of Continuous Crystallization in an Integrated Continuous Pharmaceutical Pilot Plant

Crystal growth & design
2014 | Journal article
Contributors: Zhang, Haitao; Lakerveld, Richard; Heider, Patrick L.; Tao, Mengying; Su, Min; Testa, Christopher J.; D'Antonio, Alyssa N.; Barton, Paul I.; Braatz, Richard D.; Trout, Bernhardt L. et al.
Source: check_circle
Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

Development of a Multi-Step Synthesis and Workup Sequence for an Integrated, Continuous Manufacturing Process of a Pharmaceutical

Organic process research & development
2014 | Journal article
Contributors: Heider, Patrick L.; Born, Stephen C.; Basak, Soubir; Benyahia, Brahim; Lakerveld, Richard; Zhang, Haitao; Hogan, Rachael; Buchbinder, Louis; Wolfe, Aaron; Mascia, Salvatore et al.
Source: check_circle
Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

Integrated design of microwave and photocatalytic reactors. Where are we now?

Current Opinion in Chemical Engineering
2014 | Journal article
Contributors: Lakerveld, Richard; Sturm, Gsj S.J.; Stankiewicz, Ai I.; Stefanidis, Georgios D.
Source: check_circle
Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

Microwave Assisted Fines Control during Crystallization

BIWIC 2014: 21st International Workshop on Industrial Crystallization, University of Rouen, France
2014 | Journal article
Contributors: Kacker, R.; Lakerveld, Richard; Kramer, Herman J.M.
Source: check_circle
Hong Kong University of Science and Technology

The application of an automated plant-wide control strategy for a continuous pharmaceutical pilot plant

Organic Process Research & Development
2014 | Journal article
Contributors: Lakerveld, Richard; Benyahia, Brahim; Heider, Patrick L.; Zhang, Haitao; Wolfe, Aaron; Testa, Christopher J.; Ogden, Sean; Hersey, Devin R.; Mascia, Salvatore; Evans, James M. B. et al.
Source: check_circle
Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

The application of an automated plant-wide control strategy for a continuous pharmaceutical pilot plant

Proceedings of the American Control Conference
2014 | Conference paper
Part of ISBN: 9781479932726
Contributors: Lakerveld, R.; Brahim Benyahia; Patrick L. Heider; Haitao Zhang; Aaron Wolfe; Christopher J. Testa; Sean Ogden; Devin R. Hersey; Salvatore Mascia; James M. B. Evans et al.
Source: check_circle
Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

Averaging Level Control to Reduce Off-Spec Material in a Continuous Pharmaceutical Pilot Plant

Processes
2013 | Journal article
Contributors: Richard Lakerveld; Brahim Benyahia; Patrick L. Heider; Haitao Zhang; Richard D. Braatz; Paul I. Barton
Source: check_circle
Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

Crystallization of L-ascorbic acid in a 18-L airlift crystallizer

Pharmaceutical Discovery, Development and Manufacturing Forum 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future, San Francisco, United States
2013 | Conference paper
Part of ISBN: 978-163439051-4
Contributors: Lakerveld, Richard; Van Krochten, Jeroen; Anisi, Fatemeh; Stankiewicz, Andrzej; Kramer, Herman
Source: check_circle
Hong Kong University of Science and Technology

Crystallization of L-ascorbic acid in a 18-L airlift crystallizer

Pharmaceutical Discovery, Development and Manufacturing Forum 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future
2013 | Conference paper
EID:

2-s2.0-84911461744

Contributors: Lakerveld, R.; Van Krochten, J.; Anisi, F.; Stankiewicz, A.I.; Kramer, H.J.M.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Crystallization of L-ascorbic acid in a 18-L airlift crystallizer

Separations Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future
2013 | Conference paper
EID:

2-s2.0-84911976050

Contributors: Lakerveld, R.; Van Krochten, V.J.; Anisi, F.; Stankiewicz, A.I.; Kramer, H.J.M.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

End-to-End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation

Angewandte Chemie (International ed.)
2013 | Journal article
Contributors: Mascia, Salvatore; Heider, Patrick L.; Zhang, Haitao; Lakerveld, Richard; Benyahia, Brahim; Barton, Paul I.; Braatz, Richard D.; Cooney, Charles L.; Evans, James M. B.; Jamison, Timothy F. et al.
Source: check_circle
Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

Membrane-assisted crystallization of L-ascorbic acid

Separations Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future, San Francisco, United States
2013 | Conference paper
Part of ISBN: 978-163439054-5
Contributors: Lakerveld, Richard; Goddrie, S.F.M.; Anisi, Fatemeh; Stankiewicz, Andrzej I.; Kramer, Herman J.M.
Source: check_circle
Hong Kong University of Science and Technology

Membrane-assisted crystallization of L-ascorbic acid

Separations Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future
2013 | Conference paper
EID:

2-s2.0-84911970428

Contributors: Lakerveld, R.; Goddrie, S.F.M.; Anisi, F.; Stankiewicz, A.I.; Kramer, H.J.M.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Model-Based Design of a Plant-Wide Control Strategy for a Continuous Pharmaceutical Plant

AIChE journal
2013 | Journal article
Contributors: Lakerveld, Richard; Benyahia, Brahim; Braatz, Richard D.; Barton, Paul I.
Source: check_circle
Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

A master-equation approach to simulate kinetic traps during directed self-assembly

The Journal of chemical physics
2012 | Journal article
Contributors: Lakerveld, Richard; Stephanopoulos, George; Barton, Paul I.
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Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

A Plant-Wide Dynamic Model of a Continuous Pharmaceutical Process

Industrial & engineering chemistry research
2012 | Journal article
Contributors: Benyahia, Brahim; Lakerveld, Richard; Barton, Paul I.
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Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

Minimization of Attrition and Breakage in an Airlift Crystallizer

Industrial & engineering chemistry research
2012 | Journal article
Contributors: Soare, Anamaria; Lakerveld, Richard; Van Royen, Jurjen; Zocchi, Giorgia; Stankiewicz, Andrzej I.; Kramer, Herman J. M.
Source: check_circle
Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

A master-equation approach to simulate directed self assembly

Nanoscale Science and Engineering Forum - Core Programming Topic at the 2011 AIChE Annual Meeting
2011 | Conference paper
EID:

2-s2.0-85054627529

Contributors: Lakerveld, R.; Stephanopoulos, G.; Barton, P.I.
Source: Self-asserted source
Lakerveld, Richard via Scopus - Elsevier

Application of Ultrasound for Start-Up of Evaporative Batch Crystallization of Ammonium Sulfate in a 75-L Crystallizer

AIChE journal
2011 | Journal article
Contributors: Lakerveld, Richard; Verzijden, Nelleke G.; Kramer, Herman; Jansens, Peter; Grievink, Johan
Source: check_circle
Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

Towards robust fabrication of non-periodic nanoscale systems via directed self assembly

Computer-aided chemical engineering
2011 | Conference paper
Part of ISBN: 978-0-444-53895-6
Contributors: Lakerveld, Richard; Stephanopoulos, George; Barton, Paul I.
Source: check_circle
Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

A Plant-Wide Control Strategy for Continuous Pharmaceutical Manufacturing

AlChE
2010 | Conference paper
Contributors: Lakerveld, Richard; Braatz, Richard D.; Barton, Paul I.
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Hong Kong University of Science and Technology

Application of generic principles of process intensification to solution crystallization enabled by a task-based design approach

Chemical engineering and processing
2010 | Journal article
Contributors: Lakerveld, Richard; Kramer, Herman J. M.; Stankiewicz, Andrzej I.; Grievink, Johan
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Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

Membrane assisted crystallization using reverse osmosis: Influence of solubility characteristics on experimental application and energy saving potential

Chemical engineering science
2010 | Journal article
Contributors: Lakerveld, Richard; Kuhn, Jelan; Kramer, Herman J. M.; Jansens, Peter J.; Grievink, Johan
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Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

Characterization and Dynamic Optimization of Membrane-Assisted Crystallization of Adipic Acid

Industrial & engineering chemistry research
2009 | Journal article
Contributors: Kuhn, Jelan; Lakerveld, Richard; Kramer, Herman J. M.; Grievink, Johan; Jansens, Peter J.
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Hong Kong University of Science and Technology
grade
Preferred source (of 2)‎

Opportunities for process intensification in crystallization: application of air-mixed devices

EPIC 2009 Conference Proceedings
2009 | Conference paper
Contributors: Lakerveld, R.; Kramer, H.J.M.; Stankiewicz, A.I.; Jansens, P.J.; Grievink, J.
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Hong Kong University of Science and Technology

The Application of a Task Based Design Approach to Solution Crystallization

Design for Energy and the Environment: Proceedings of the Seventh International Conference on the Foundations of Computer-Aided Process Design
2009 | Conference paper
Contributors: Lakerveld, Richard; Kramer, Herman J.M.; Jansens, Peter J.; Grievink, Johan
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Hong Kong University of Science and Technology
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Page 1 of 2

Peer review (31 reviews for 6 publications/grants)

Review activity for ACS applied materials & interfaces. (2)
Review activity for ACS omega. (1)
Review activity for Chemical engineering research & design. (1)
Review activity for Crystal growth & design. (9)
Review activity for Industrial & engineering chemistry research. (17)
Review activity for Organic process research & development. (1)