Personal information

Genetics, Cerebrovascular Disease, Biomarkers, Epigenetics

Activities

Employment (4)

UCSF: San Francisco, California, US

2019-10-01 to present | Assistant Professor (Anesthesia and Perioperative Care)
Employment
Source: Self-asserted source
Shantel Weinsheimer

Institute of Biological Psychiatry: Roskilde, DK

2014-07 to 2019-09 | Senior Postdoc
Employment
Source: Self-asserted source
Shantel Weinsheimer

UCSF: San Francisco, CA, US

2008-01 to 2012-04 | Postdoctoral Fellow (Center for Cerebrovascular Research)
Employment
Source: Self-asserted source
Shantel Weinsheimer

Lawrence Berkeley National Laboratory: Berkeley, CA, US

2007-05 to 2007-12 | Postdoctoral Fellow
Employment
Source: Self-asserted source
Shantel Weinsheimer

Education and qualifications (3)

Wayne State University: Detroit, Michigan, US

2006-08 | PhD (Molecular Biology & Genetics) (Center for Molecular Medicine and Genetics)
Qualification
Source: Self-asserted source
Shantel Weinsheimer

Wayne State University School of Medicine: Detroit, MI, US

2002-06 | MS (Basic Medical Sciences)
Qualification
Source: Self-asserted source
Shantel Weinsheimer

Otterbein College: Westerville, OH, US

1999-06 | BS (Biochemistry)
Qualification
Source: Self-asserted source
Shantel Weinsheimer

Professional activities (4)

International Pediatric Stroke Organization: Victoria, CA

2021-01 to present
Membership
Source: Self-asserted source
Shantel Weinsheimer

American Heart Association: Dallas, TX, US

2020 to present
Membership
Source: Self-asserted source
Shantel Weinsheimer

American Society of Human Genetics: Rockville, MD, US

2005 to present
Membership
Source: Self-asserted source
Shantel Weinsheimer

International Society of Psychiatric Genetics: Brentwood, TN, US

2014 to 2017
Membership
Source: Self-asserted source
Shantel Weinsheimer

Funding (2)

Epigenetic Signatures and Association with Hemorrhage and High Risk Features in Brain Arteriovenous Malformation

2024-04-01 to 2027-03-31 | Grant
American Heart Association (Dallas, US)
GRANT_NUMBER:

24CDA1271334

Source: check_circle
American Heart Association

Brain Vascular Malformation Consortium: Predictors of Clinical Course. (PD: Helen Kim)

Grant
NIH/NINDS (Rockville, US)
GRANT_NUMBER:

U54 NS065705

Source: Self-asserted source
Shantel Weinsheimer

Works (39)

Mild Hypoxia Accelerates Cerebral Cavernous Malformation Disease Through CX3CR1-CX3CL1 Signaling

Arteriosclerosis, Thrombosis, and Vascular Biology
2024-06 | Journal article
Contributors: Eduardo Frias-Anaya; Helios Gallego-Gutierrez; Brendan Gongol; Shantel Weinsheimer; Catherine Chinhchu Lai; Marco Orecchioni; Aditya Sriram; Cassandra M. Bui; Bliss Nelsen; Preston Hale et al.
Source: check_circle
Crossref

Intracranial Hemorrhage Rate and Lesion Burden in Patients With Familial Cerebral Cavernous Malformation

Journal of the American Heart Association
2023-02-07 | Journal article
Contributors: Shantel Weinsheimer; Jeffrey Nelson; Adib A. Abla; Nerissa U. Ko; Cynthia Tsang; Obiora Okoye; Joseph M. Zabramski; Amy Akers; Atif Zafar; Marc C. Mabray et al.
Source: check_circle
Crossref

Maternal and Fetal Outcomes in Women with Brain Arteriovenous Malformation Rupture during Pregnancy

Cerebrovascular Diseases (In Press)
2021 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Somatic mosaicism in the mapk pathway in sporadic brain arteriovenous malformation and association with phenotype.

J Neurosurg (In Press)
2021 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Assessing the association of common genetic variants in EPHB4 and RASA1 with phenotype severity in familial cerebral cavernous malformation

Molecular Genetics & Genomic Medicine
2021-10 | Journal article
Contributors: Foram Choksi; Shantel Weinsheimer; Jeffrey Nelson; Ludmila Pawlikowska; Christine K. Fox; Atif Zafar; Marc C. Mabray; Joseph Zabramski; Amy Akers; Blaine L. Hart et al.
Source: check_circle
Crossref

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank.

Nature communications
2020-05-08 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder.

Molecular psychiatry
2020-03-16 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank.

Molecular psychiatry
2020-01-23 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.

Molecular psychiatry
2019-11-11 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls.

Biological psychiatry
2019-11-01 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression.

Biological psychiatry
2019-08-05 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns.

Nature communications
2019-06-11 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Identification of common genetic risk variants for autism spectrum disorder.

Nature genetics
2019-02-25 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder.

Communications biology
2018-10-08 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank.

Biological psychiatry. Cognitive neuroscience and neuroimaging
2018-07-31 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Prevalence of rearrangements in the 22q11.2 region and population-based risk of neuropsychiatric and developmental disorders in a Danish population: a case-cohort study.

The lancet. Psychiatry
2018-06-07 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.

Nature genetics
2018-04-26 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations.

JAMA psychiatry
2017-12-01 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium.

Biological psychiatry
2017-09-21 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome.

Translational psychiatry
2017-08-29 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

An epigenetic clock for gestational age at birth based on blood methylation data.

Genome biology
2016-10-07 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Genome-wide association study of sporadic brain arteriovenous malformations.

Journal of neurology, neurosurgery, and psychiatry
2016-01-27 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Molecular basis and genetic predisposition to intracranial aneurysm.

Annals of medicine
2014-08-12 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Evaluation of genetic risk loci for intracranial aneurysms in sporadic arteriovenous malformations of the brain.

Journal of neurology, neurosurgery, and psychiatry
2014-07-21 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Common variants on 9p21.3 are associated with brain arteriovenous malformations with accompanying arterial aneurysms.

Journal of neurology, neurosurgery, and psychiatry
2014-04-28 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

A genome-wide investigation of copy number variation in patients with sporadic brain arteriovenous malformation.

PloS one
2013-10-03 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

G Protein-Coupled Receptor 124 (GPR124) Gene Polymorphisms and Risk of Brain Arteriovenous Malformation.

Translational stroke research
2012-08-14 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Gene expression profiling of blood in brain arteriovenous malformation patients.

Translational stroke research
2011-12-01 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Angiopoietin-like 4 (ANGPTL4) gene polymorphisms and risk of brain arteriovenous malformations.

Cerebrovascular diseases (Basel, Switzerland)
2011-01-07 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Brain arteriovenous malformation pathogenesis: a response-to-injury paradigm.

Acta neurochirurgica. Supplement
2011-01-01 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

EPHB4 gene polymorphisms and risk of intracranial hemorrhage in patients with brain arteriovenous malformations.

Circulation. Cardiovascular genetics
2009-08-22 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm.

Nature genetics
2008-01-06 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Effects of cathepsins B and L inhibition on postischemic protein alterations in the brain.

Biochemical and biophysical research communications
2007-12-03 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Integration of expression profiles and genetic mapping data to identify candidate genes in intracranial aneurysm.

Physiological genomics
2007-09-18 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Association of kallikrein gene polymorphisms with intracranial aneurysms.

Stroke
2007-08-30 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Whole genome expression profiling reveals a significant role for immune function in human abdominal aortic aneurysms.

BMC genomics
2007-07-16 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

LARALink: a web application for cytogenetic linkage analysis.

Clinical genetics
2005-04-01 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

Structural determinants of the calpain inhibitory activity of calpastatin peptide B27-WT.

The Journal of biological chemistry
2002-12-24 | Journal article
Source: Self-asserted source
Shantel Weinsheimer

A selective cysteine protease inhibitor is non-toxic and cerebroprotective in rats undergoing transient middle cerebral artery ischemia.

Brain research
2001-05-01 | Journal article
Source: Self-asserted source
Shantel Weinsheimer