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University of British Columbia: Vancouver, BC, CA

1995-01-01 to present | Professor (Cellular and Physiological Science)
Employment
Source: Self-asserted source
Edwin DW Moore

Works (50)

Phosphorylation of RyR2 simultaneously expands the dyad and rearranges the tetramers

Journal of General Physiology
2024-04-01 | Journal article
Contributors: Parisa Asghari; David R.L. Scriven; Saba Shahrasebi; Hector H. Valdivia; Katherina M. Alsina; Carmen R. Valdivia; J. Alberto Navarro-Garcia; Xander H.T. Wehrens; Edwin D.W. Moore
Source: check_circle
Crossref

Cardiomyocyte ryanodine receptor clusters expand and coalesce after application of isoproterenol

Journal of General Physiology
2023-11-06 | Journal article
Contributors: David R.L. Scriven; Anne Berit Johnsen; Parisa Asghari; Keng C. Chou; Edwin D.W. Moore
Source: check_circle
Crossref

Cardiac ryanodine receptor distribution is dynamic and changed by auxiliary proteins and post-translational modification

eLife
2020-01-09 | Journal article
Contributors: Parisa Asghari; David RL Scriven; Myles Ng; Pankaj Panwar; Keng C Chou; Filip van Petegem; Edwin DW Moore
Source: check_circle
Crossref

Ca2+ signaling machinery is present at intercellular junctions and structures associated with junction turnover in rat Sertoli cells†

Biology of Reproduction
2017-06 | Journal article
Part of ISSN: 0006-3363
Part of ISSN: 1529-7268
Source: Self-asserted source
Edwin DW Moore

Cardiac Ryanodine Receptor (Ryr2)-mediated Calcium Signals Specifically Promote Glucose Oxidation via Pyruvate Dehydrogenase.

The Journal of biological chemistry
2016-09-12 | Journal article
Source: Self-asserted source
Edwin DW Moore

Single molecule localization deep within thick cells; a novel super-resolution microscope

Journal of Biophotonics
2016-01 | Journal article
Part of ISSN: 1864-063X
Source: Self-asserted source
Edwin DW Moore

Nonuniform and Variable Arrangements of Ryanodine Receptors Within Mammalian Ventricular Couplons

Circulation Research
2014-07-07 | Journal article
Part of ISSN: 0009-7330
Part of ISSN: 1524-4571
Source: Self-asserted source
Edwin DW Moore

Ca2+ channel and Na+/Ca2+ exchange localization in cardiac myocytes

Journal of Molecular and Cellular Cardiology
2013-05 | Journal article
Part of ISSN: 0022-2828
Source: Self-asserted source
Edwin DW Moore

Microarchitecture of the dyad

Cardiovascular Research
2013-05-01 | Journal article
Part of ISSN: 1755-3245
Part of ISSN: 0008-6363
Source: Self-asserted source
Edwin DW Moore

Cardiac ryanodine receptors control heart rate and rhythmicity in adult mice

Cardiovascular Research
2012-12-01 | Journal article
Part of ISSN: 0008-6363
Source: Self-asserted source
Edwin DW Moore

Editorial

Protoplasma
2012-02 | Journal article
Part of ISSN: 0033-183X
Part of ISSN: 1615-6102
Source: Self-asserted source
Edwin DW Moore

The structure and functioning of the couplon in the mammalian cardiomyocyte.

Protoplasma
2011-11-05 | Journal article
Source: Self-asserted source
Edwin DW Moore

Couplons in rat atria form distinct subgroups defined by their molecular partners.

Journal of cell science
2011-03-08 | Journal article
Source: Self-asserted source
Edwin DW Moore

Analysis of Cav1.2 and ryanodine receptor clusters in rat ventricular myocytes.

Biophysical journal
2010-12-01 | Journal article
Source: Self-asserted source
Edwin DW Moore

Multi-image colocalization and its statistical significance.

Biophysical journal
2010-09-01 | Journal article
Source: Self-asserted source
Edwin DW Moore

Integrin-mediated adhesion maintains sarcomeric integrity.

Developmental biology
2009-10-29 | Journal article
Source: Self-asserted source
Edwin DW Moore

Axial tubules of rat ventricular myocytes form multiple junctions with the sarcoplasmic reticulum.

Biophysical journal
2009-06-01 | Journal article
Source: Self-asserted source
Edwin DW Moore

A signaling pathway contributing to platelet storage lesion development: targeting PI3-kinase-dependent Rap1 activation slows storage-induced platelet deterioration.

Transfusion
2009-05-18 | Journal article
Source: Self-asserted source
Edwin DW Moore

Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.

Proceedings of the National Academy of Sciences of the United States of America
2009-04-21 | Journal article
Source: Self-asserted source
Edwin DW Moore

Image acquisition for colocalization using optical microscopy.

American journal of physiology. Cell physiology
2008-03-19 | Journal article
Source: Self-asserted source
Edwin DW Moore

Clearance of store-released Ca2+ by the Na+-Ca2+ exchanger is diminished in aortic smooth muscle from Na+-K+-ATPase alpha 2-isoform gene-ablated mice.

American journal of physiology. Heart and circulatory physiology
2008-01-11 | Journal article
Source: Self-asserted source
Edwin DW Moore

Subcellular characterization of glucose uptake in coronary endothelial cells.

Microvascular research
2007-04-25 | Journal article
Source: Self-asserted source
Edwin DW Moore

Localization of Kv1.5 channels in rat and canine myocyte sarcolemma.

FEBS letters
2006-10-12 | Journal article
Source: Self-asserted source
Edwin DW Moore

Asymmetric subcellular distribution of glucose transporters in the endothelium of small contractile arteries.

Endothelium : journal of endothelial cell research
2006-09-01 | Journal article
Source: Self-asserted source
Edwin DW Moore

Caveolin-3 is adjacent to a group of extradyadic ryanodine receptors.

Biophysical journal
2005-06-24 | Journal article
Source: Self-asserted source
Edwin DW Moore

Characterisation of glucose transporters in the intact coronary artery endothelium in rats: GLUT-2 upregulated by long-term hyperglycaemia.

Diabetologia
2004-12-10 | Journal article
Source: Self-asserted source
Edwin DW Moore

Molecular properties of cardiac tail-anchored membrane protein SLMAP are consistent with structural role in arrangement of excitation-contraction coupling apparatus.

American journal of physiology. Heart and circulatory physiology
2004-12-09 | Journal article
Source: Self-asserted source
Edwin DW Moore

Helicobacter pylori infection targets adherens junction regulatory proteins and results in increased rates of migration in human gastric epithelial cells.

Infection and immunity
2004-09-01 | Journal article
Source: Self-asserted source
Edwin DW Moore

Regulated expression and temporal induction of the tail-anchored sarcolemmal-membrane-associated protein is critical for myoblast fusion.

The Biochemical journal
2004-08-01 | Journal article
Source: Self-asserted source
Edwin DW Moore

Deconvolution of confocal images of dihydropyridine and ryanodine receptors in developing cardiomyocytes.

Journal of applied physiology (Bethesda, Md. : 1985)
2004-04-02 | Journal article
Source: Self-asserted source
Edwin DW Moore

Increased focal Kv4.2 channel expression at the plasma membrane is the result of actin depolymerization.

American journal of physiology. Heart and circulatory physiology
2003-10-09 | Journal article
Source: Self-asserted source
Edwin DW Moore

Epitope-dependent localization of estrogen receptor-alpha, but not -beta, in en face arterial endothelium.

American journal of physiology. Heart and circulatory physiology
2002-12-12 | Journal article
Source: Self-asserted source
Edwin DW Moore

The molecular architecture of calcium microdomains in rat cardiomyocytes.

Annals of the New York Academy of Sciences
2002-11-01 | Journal article
Source: Self-asserted source
Edwin DW Moore

Pressure-dependent myogenic constriction of cerebral arteries occurs independently of voltage-dependent activation.

American journal of physiology. Heart and circulatory physiology
2002-08-15 | Journal article
Source: Self-asserted source
Edwin DW Moore

Distribution of proteins implicated in excitation-contraction coupling in rat ventricular myocytes.

Biophysical journal
2000-11-01 | Journal article
Source: Self-asserted source
Edwin DW Moore

Colocalization of dihydropyridine and ryanodine receptors in neonate rabbit heart using confocal microscopy.

American journal of physiology. Heart and circulatory physiology
2000-07-01 | Journal article
Source: Self-asserted source
Edwin DW Moore

alpha-actinin-2 couples to cardiac Kv1.5 channels, regulating current density and channel localization in HEK cells.

FEBS letters
2000-05-01 | Journal article
Source: Self-asserted source
Edwin DW Moore

Distribution of active protein kinase C in smooth muscle.

Biophysical journal
1999-08-01 | Journal article
Source: Self-asserted source
Edwin DW Moore

The role of protein kinase C isozymes in bombesin-stimulated gastrin release from human antral gastrin cells.

The Journal of biological chemistry
1999-08-01 | Journal article
Source: Self-asserted source
Edwin DW Moore

Uptake of oxidized LDL by macrophages differs from that of acetyl LDL and leads to expansion of an acidic endolysosomal compartment.

Arteriosclerosis, thrombosis, and vascular biology
1999-08-01 | Journal article
Source: Self-asserted source
Edwin DW Moore

Superresolution three-dimensional images of fluorescence in cells with minimal light exposure.

Science (New York, N.Y.)
1995-06-01 | Journal article
PMID: 7770772
Source: Self-asserted source
Edwin DW Moore

Coupling of the Na+/Ca2+ exchanger, Na+/K+ pump and sarcoplasmic reticulum in smooth muscle.

Nature
1993-10-01 | Journal article
PMID: 8413629
Source: Self-asserted source
Edwin DW Moore

Isoproterenol stimulates rapid extrusion of sodium from isolated smooth muscle cells.

Proceedings of the National Academy of Sciences of the United States of America
1993-09-01 | Journal article
PMID: 8367463
Source: Self-asserted source
Edwin DW Moore

Cellular and molecular physiology of calcium signalling in smooth muscle cells.

Japanese journal of pharmacology
1992-01-01 | Journal article
PMID: 1507595
Source: Self-asserted source
Edwin DW Moore

Adenosine reduces the Ca2+ transients of isoproterenol-stimulated rat ventricular myocytes.

The American journal of physiology
1991-12-01 | Journal article
PMID: 1767814
Source: Self-asserted source
Edwin DW Moore

Calcium homeostasis in single intact smooth muscle cells.

Advances in experimental medicine and biology
1991-01-01 | Journal article
PMID: 1803898
Source: Self-asserted source
Edwin DW Moore

Role of Na(+)-Ca2+ exchanger in beta-adrenergic relaxation of single smooth muscle cells.

Annals of the New York Academy of Sciences
1991-01-01 | Journal article
PMID: 1664707
Source: Self-asserted source
Edwin DW Moore

Ca2+ imaging in single living cells: theoretical and practical issues.

Cell calcium
1990-02-01 | Journal article
PMID: 2191780
Source: Self-asserted source
Edwin DW Moore

Practical aspects of the use of photoproteins as biological calcium indicators.

Society of General Physiologists series
1986-01-01 | Journal article
PMID: 3520836
Source: Self-asserted source
Edwin DW Moore

Plasma and tissue concentrations of hycanthone in the mouse determined by reversed-phase high-performance liquid chromatography.

Journal of chromatography
1980-09-01 | Journal article
PMID: 7419657
Source: Self-asserted source
Edwin DW Moore