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Employment (2)

Leiden University: Leiden, South Holland, NL

2024-01-01 to present | Postdoc (Institute of Biology Leiden)
Employment
Source: Self-asserted source
Ned P. Buijs

Universiteit Leiden Instituut Biologie Leiden: Leiden, Zuid-Holland, NL

2019-04-01 to 2023-12-20 | PhD Candidate (Biological Chemistry)
Employment
Source: Self-asserted source
Ned P. Buijs

Education and qualifications (2)

Leiden University: Leiden, South Holland, NL

2019-04-01 to 2023-12-20 | PhD (Institute of Biology Leiden)
Education
Source: Self-asserted source
Ned P. Buijs

University of Glasgow: Glasgow, Scotland, GB

2013-09-01 to 2018-06-01 | MSci Chemistry (Chemistry)
Education
Source: Self-asserted source
Ned P. Buijs

Works (11)

A classic antibiotic reimagined: Rationally designed bacitracin variants exhibit potent activity against vancomycin-resistant pathogens

Proceedings of the National Academy of Sciences
2024-07-16 | Journal article
DOI: 10.1073/pnas.2315310121
Contributors: Ned P. Buijs; Halana C. Vlaming; Ioli Kotsogianni; Melina Arts; Joost Willemse; Yunhao Duan; Francesca M. Alexander; Stephen A. Cochrane; Tanja Schneider; Nathaniel I. Martin
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Crossref
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Discovery and derivatization of tridecaptin antibiotics with altered host specificity and enhanced bioactivity

ACS Chemical Biology
2024-04-11 | Journal article
DOI: 10.1021/acschembio.4c00034
OTHER-ID:

937a100a-8570-43ef-b7d9-45c4715d16b9
Contributors: Machushynets; V.; Al Ayed; K.; Terlouw; R.; Du; C.; Buijs; P.; Willemse; J.; Elsayed; S.; Schill; J.; Trebosc; V.: Pieren et al.
Source: check_circle
Leiden University

Targeting membrane-bound bacterial cell wall precursors: a tried and true antibiotic strategy in nature and the clinic

Chemical Communications
2023 | Journal article
DOI: 10.1039/D3CC01070H
Contributors: Ned P. Buijs; Eilidh J. Matheson; Stephen A. Cochrane; Nathaniel I. Martin
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Crossref

Next generation bacitracin

2023-12-20 | Dissertation or Thesis
OTHER-ID:

c7ec30ad-dbf7-4db4-92f2-12aece15f2de
Contributors: Buijs; N.P.
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Leiden University

Synthetic Studies with Bacitracin A and Preparation of Analogues Containing Alternative Zinc Binding Groups

ChemBioChem
2022-12-16 | Journal article
DOI: 10.1002/cbic.202200547
Contributors: Ned Buijs; Halana C. Vlaming; Matthijs J. van Haren; Nathaniel I. Martin
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Crossref
grade
Preferred source (of 2)‎

Mechanistic insights into the C55-P targeting lipopeptide antibiotics revealed by structure–activity studies and high-resolution crystal structures

Chemical Science
2022-02-21 | Journal article
DOI: 10.1039/d1sc07190d
Part of ISSN: 2041-6520
Part of ISSN: 2041-6539
Contributors: Ned P. Buijs
Source: Self-asserted source
Ned P. Buijs
grade
Preferred source (of 2)‎

Esterase-Sensitive Prodrugs of a Potent Bisubstrate Inhibitor of Nicotinamide N-Methyltransferase (NNMT) Display Cellular Activity

Biomolecules
2021-09-14 | Journal article
DOI: 10.3390/biom11091357
Part of ISSN: 2218-273X
Contributors: Ned P. Buijs
Source: Self-asserted source
Ned P. Buijs
grade
Preferred source (of 2)‎

Potent Inhibition of Nicotinamide N-Methyltransferase by Alkene-Linked Bisubstrate Mimics Bearing Electron Deficient Aromatics

Journal of Medicinal Chemistry
2021-08-23 | Journal article
DOI: 10.1021/acs.jmedchem.1c01094
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Ned P. Buijs
Source: Self-asserted source
Ned P. Buijs
grade
Preferred source (of 2)‎

Macrocyclic peptides as allosteric inhibitors of nicotinamide N-methyltransferase (NNMT)

RSC Chemical Biology
2021-08-19 | Journal article
DOI: 10.1039/d1cb00134e
Part of ISSN: 2633-0679
Contributors: Ned P. Buijs
Source: Self-asserted source
Ned P. Buijs
grade
Preferred source (of 2)‎

Synthesis and Photophysical Properties of Benzotriazole-Derived Unnatural α-Amino Acids

The Journal of Organic Chemistry
2019-07-24 | Journal article
DOI: 10.1021/acs.joc.9b01685
Part of ISSN: 0022-3263
Part of ISSN: 1520-6904
Contributors: Ned P. Buijs
Source: Self-asserted source
Ned P. Buijs

Synthesis of Structurally Diverse Benzotriazoles via Rapid Diazotization and Intramolecular Cyclization of 1,2‐Aryldiamines

European Journal of Organic Chemistry
2019-04-16 | Journal article
DOI: 10.1002/ejoc.201900463
Part of ISSN: 1434-193X
Part of ISSN: 1099-0690
Contributors: Ned P. Buijs
Source: Self-asserted source
Ned P. Buijs

Peer review (1 review for 1 publication/grant)

Review activity for Bioorganic chemistry. (1)
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