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Works (14)

TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C.

The Journal of experimental medicine
2021-12 | Journal article
DOI: 10.1084/jem.20211381
PMID: 34914824
PMC: PMC8685281
Contributors: Hoste L; Roels L; Naesens L; Bosteels V; Vanhee S; Dupont S; Bosteels C; Browaeys R; Vandamme N; Verstaen K et al.
Source: Self-asserted source
Leen J.M. Seys via Europe PubMed Central

Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID): a factorial, randomised, controlled trial.

The Lancet. Respiratory medicine
2021-10 | Journal article
DOI: 10.1016/s2213-2600(21)00377-5
PMID: 34756178
PMC: PMC8555973
Contributors: Declercq J; Van Damme KFA; De Leeuw E; Maes B; Bosteels C; Tavernier SJ; De Buyser S; Colman R; Hites M; Verschelden G et al.
Source: Self-asserted source
Leen J.M. Seys via Europe PubMed Central

ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation.

Cell reports
2021-08 | Journal article
DOI: 10.1016/j.celrep.2021.109500
PMID: 34380029
Contributors: de Reuver R; Dierick E; Wiernicki B; Staes K; Seys L; De Meester E; Muyldermans T; Botzki A; Lambrecht BN; Van Nieuwerburgh F et al.
Source: Self-asserted source
Leen J.M. Seys via Europe PubMed Central

ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation

2020-12 | Preprint
DOI: 10.1101/2020.12.04.411702
PPR: PPR249065
Contributors: de Reuver R; Dierick E; Wiernicki B; Staes K; Seys L; De Meester E; Muyldermans T; Botzki A; Lambrecht B; Van Nieuwerburgh F et al.
Source: Self-asserted source
Leen J.M. Seys via Europe PubMed Central

DPP4, the Middle East Respiratory Syndrome Coronavirus Receptor, is Upregulated in Lungs of Smokers and Chronic Obstructive Pulmonary Disease Patients.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
2018-01 | Journal article
DOI: 10.1093/cid/cix741
PMID: 29020176
PMC: PMC7108100
Contributors: Seys LJM; Widagdo W; Verhamme FM; Kleinjan A; Janssens W; Joos GF; Bracke KR; Haagmans BL; Brusselle GG
Source: Self-asserted source
Leen J.M. Seys via Europe PubMed Central

Association of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD.

International journal of chronic obstructive pulmonary disease
2017-12 | Journal article
DOI: 10.2147/copd.s144136
PMID: 29296079
PMC: PMC5741069
Contributors: De Smet EG; Seys LJ; Verhamme FM; Vanaudenaerde BM; Brusselle GG; Bingle CD; Bracke KR
Source: Self-asserted source
Leen J.M. Seys via Europe PubMed Central

Epidemiology and impact of chronic bronchitis in chronic obstructive pulmonary disease.

The European respiratory journal
2017-08 | Journal article
DOI: 10.1183/13993003.02470-2016
PMID: 28798087
PMC: PMC5593375
Contributors: Lahousse L; Seys LJM; Joos GF; Franco OH; Stricker BH; Brusselle GG
Source: Self-asserted source
Leen J.M. Seys via Europe PubMed Central

Elevated GDF-15 contributes to pulmonary inflammation upon cigarette smoke exposure.

Mucosal immunology
2017-02 | Journal article
DOI: 10.1038/mi.2017.3
PMID: 28145442
Contributors: Verhamme FM; Seys LJM; De Smet EG; Provoost S; Janssens W; Elewaut D; Joos GF; Brusselle GG; Bracke KR
Source: Self-asserted source
Leen J.M. Seys via Europe PubMed Central

MicroRNA Profiling Reveals a Role for MicroRNA-218-5p in the Pathogenesis of Chronic Obstructive Pulmonary Disease.

American journal of respiratory and critical care medicine
2017-01 | Journal article
DOI: 10.1164/rccm.201506-1182oc
PMID: 27409149
Contributors: Conickx G; Mestdagh P; Avila Cobos F; Verhamme FM; Maes T; Vanaudenaerde BM; Seys LJ; Lahousse L; Kim RY; Hsu AC et al.
Source: Self-asserted source
Leen J.M. Seys via Europe PubMed Central

B cells in chronic obstructive pulmonary disease: moving to center stage.

American journal of physiology. Lung cellular and molecular physiology
2016-08 | Journal article
DOI: 10.1152/ajplung.00304.2016
PMID: 27542809
PMC: PMC5142126
Contributors: Polverino F; Seys LJ; Bracke KR; Owen CA
Source: Self-asserted source
Leen J.M. Seys via Europe PubMed Central

Dysregulation of type 2 innate lymphoid cells and T<sub>H</sub>2 cells impairs pollutant-induced allergic airway responses.

The Journal of allergy and clinical immunology
2016-05 | Journal article
DOI: 10.1016/j.jaci.2016.03.044
PMID: 27315767
PMC: PMC5420012
Contributors: De Grove KC; Provoost S; Hendriks RW; McKenzie ANJ; Seys LJM; Kumar S; Maes T; Brusselle GG; Joos GF
Source: Self-asserted source
Leen J.M. Seys via Europe PubMed Central

Role of B Cell-Activating Factor in Chronic Obstructive Pulmonary Disease.

American journal of respiratory and critical care medicine
2015-09 | Journal article
DOI: 10.1164/rccm.201501-0103oc
PMID: 26266827
Contributors: Seys LJ; Verhamme FM; Schinwald A; Hammad H; Cunoosamy DM; Bantsimba-Malanda C; Sabirsh A; McCall E; Flavell L; Herbst R et al.
Source: Self-asserted source
Leen J.M. Seys via Europe PubMed Central

Airway Surface Dehydration Aggravates Cigarette Smoke-Induced Hallmarks of COPD in Mice.

PloS one
2015-06 | Journal article
DOI: 10.1371/journal.pone.0129897
PMID: 26066648
PMC: PMC4466573
Contributors: Seys LJ; Verhamme FM; Dupont LL; Desauter E; Duerr J; Seyhan Agircan A; Conickx G; Joos GF; Brusselle GG; Mall MA et al.
Source: Self-asserted source
Leen J.M. Seys via Europe PubMed Central

Role of CXCL13 in cigarette smoke-induced lymphoid follicle formation and chronic obstructive pulmonary disease.

American journal of respiratory and critical care medicine
2013-08 | Journal article
DOI: 10.1164/rccm.201211-2055oc
PMID: 23742729
Contributors: Bracke KR; Verhamme FM; Seys LJ; Bantsimba-Malanda C; Cunoosamy DM; Herbst R; Hammad H; Lambrecht BN; Joos GF; Brusselle GG
Source: Self-asserted source
Leen J.M. Seys via Europe PubMed Central
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