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Discovery of Orally Available Prodrugs of Itaconate and Derivatives

JOURNAL OF MEDICINAL CHEMISTRY
2025 | Journal article
DOI: 10.1021/acs.jmedchem.4c02646
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Lee, Chae Bin; Snajdr, Ivan; Tenora, Lukas; Alt, Jesse and Gori, Sadakatali; Krecmerova, Marcela; Maragakis, R. Michael and Paule, James; Tiwari, Sandhya; Iyer, Jitesh; Talwar, Rashmi and Garza, Luis; Majer, Pavel et al.
Source: Self-asserted source
Marcela Krecmerova

Nucleoside Chemistry at the Institute of Organic Chemistry and Biochemistry - Looking Back on History

CHEMICKE LISTY
2024 | Journal article
DOI: 10.54779/chl20240311
Part of ISSN: 0009-2770
Part of ISSN: 1213-7103
Contributors: Krecmerova, Marcela
Source: Self-asserted source
Marcela Krecmerova

Pro-905, a Novel Purine Antimetabolite, Combines with Glutamine Amidotransferase Inhibition to Suppress Growth of Malignant Peripheral Nerve Sheath Tumor

MOLECULAR CANCER THERAPEUTICS
2023 | Journal article
DOI: 10.1158/1535-7163.MCT-23-0258
Part of ISSN: 1535-7163
Part of ISSN: 1538-8514
Contributors: Lemberg, Kathryn M.; Ali, Eunus S.; Krecmerova, Marcela and Aguilar, Joanna Marie H.; Alt, Jesse; Peters, Diane E.; Zhao, Liang; Wu, Ying; Nuha, Naziba; Asara, John M.; Staedtke, Verena et al.
Source: Self-asserted source
Marcela Krecmerova

FROM 5-AZAPYRIMIDINE CHEMISTRY TO THIADIAZOLES

CHEMICKE LISTY
2022 | Journal article
DOI: 10.54779/chl20220152
Part of ISSN: 0009-2770
Part of ISSN: 1213-7103
Contributors: Krecmerova, Marcela
Source: Self-asserted source
Marcela Krecmerova

Phosphonates and Phosphonate Prodrugs in Medicinal Chemistry: Past Successes and Future Prospects

FRONTIERS IN CHEMISTRY
2022 | Journal article
DOI: 10.3389/fchem.2022.889737
Part of ISSN: 2296-2646
Contributors: Krecmerova, Marcela; Majer, Pavel; Rais, Rana; Slusher, Barbara S.
Source: Self-asserted source
Marcela Krecmerova

Poxviruses Bearing DNA Polymerase Mutations Show Complex Patterns of Cross-Resistance

BIOMEDICINES
2022 | Journal article
DOI: 10.3390/biomedicines10030580
Part of ISSN: 2227-9059
Contributors: Andrei, Graciela; Fiten, Pierre; Krecmerova, Marcela and Opdenakker, Ghislain; Topalis, Dimitrios; Snoeck, Robert
Source: Self-asserted source
Marcela Krecmerova

1,2,4-Thiadiazole acyclic nucleoside phosphonates as inhibitors of cysteine dependent enzymes cathepsin K and GSK-3β

BIOORGANIC & MEDICINAL CHEMISTRY
2021 | Journal article
DOI: 10.1016/j.bmc.2021.115998
Part of ISSN: 0968-0896
Part of ISSN: 1464-3391
Contributors: Pomeislova, Alice; Otmar, Miroslav; Rubesova, Petra; Benysek, Jakub; Matousova, Marika; Mertlikova-Kaiserova, Helena; Pohl, Radek; Slavetinska, Lenka Postova; Pomeisl, Karel; Krecmerova, Marcela
Source: Self-asserted source
Marcela Krecmerova

A novel protide purine antimetabolite combines with the prodrug glutamine antagonist JHU395 in preclinical models of Ras-driven sarcomas.

CANCER RESEARCH
2021 | Journal article
Part of ISSN: 0008-5472
Part of ISSN: 1538-7445
Contributors: Lemberg, Kathryn M.; Aguilar, Joanna Marie H.; Alt, Jesse and Krecmerova, Marcela; Majer, Pavel; Rais, Rana; Slusher, Barbara
Source: Self-asserted source
Marcela Krecmerova

Alkoxylalkyl Esters of Nucleotide Analogs Inhibit Polyomavirus DNA Replication and Large T Antigen Activities

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
2021 | Journal article
DOI: 10.1128/AAC.01641-20
Part of ISSN: 0066-4804
Part of ISSN: 1098-6596
Contributors: Onwubiko, Nichodemus O.; Diaz, Suraya A.; Krecmerova, Marcela and Nasheuer, Heinz Peter
Source: Self-asserted source
Marcela Krecmerova

Phosphofructokinases A and B from <i>Mycobacterium tuberculosis</i> Display Different Catalytic Properties and Allosteric Regulation

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021 | Journal article
DOI: 10.3390/ijms22031483
Part of ISSN: 1661-6596
Part of ISSN: 1422-0067
Contributors: Snasel, Jan; Machova, Iva; Solinova, Veronika; Kasicka, Vaclav; Krecmerova, Marcela; Pichova, Iva
Source: Self-asserted source
Marcela Krecmerova

Comparative analysis of epigenetic inhibitors reveals different degrees of interference with transcriptional gene silencing and induction of DNA damage

PLANT JOURNAL
2020 | Journal article
DOI: 10.1111/tpj.14612
Part of ISSN: 0960-7412
Part of ISSN: 1365-313X
Contributors: Nowicka, Anna; Tokarz, Barbara; Zwyrtkova, Jana; Tomastikova, Eva Dvorak; Prochazkova, Klara; Ercan, Ugur; Finke, Andreas and Rozhon, Wilfried; Poppenberger, Brigitte; Otmar, Miroslav and Niezgodzki, Igor; Krecmerova, Marcela et al.
Source: Self-asserted source
Marcela Krecmerova

Effect of Different DNA Demethylating Agents on <i>In vitro</i> Cultures of Peach Rootstock GF 677

NOTULAE BOTANICAE HORTI AGROBOTANICI CLUJ-NAPOCA
2019 | Journal article
DOI: 10.15835/nbha47311373
Part of ISSN: 0255-965X
Part of ISSN: 1842-4309
Contributors: Baranek, Miroslav; Otmar, Miroslav; Krecmerova, Marcela and Eichmeier, Ales; Moudra, Jana; Mynarzova, Zuzana
Source: Self-asserted source
Marcela Krecmerova

Enantioselective resolution of side-chain modified <i>gem</i>-difluorinated alcohols catalysed by <i>Candida antarctica</i> lipase B and monitored by capillary electrophoresis

BIOORGANIC & MEDICINAL CHEMISTRY
2019 | Journal article
DOI: 10.1016/j.bmc.2019.02.022
Part of ISSN: 0968-0896
Part of ISSN: 1464-3391
Contributors: Pomeisl, Karel; Lamatova, Nikola; Solinova, Veronika; Pohl, Radek; Brabcova, Jana; Kasicka, Vaclav; Krecmerova, Marcela
Source: Self-asserted source
Marcela Krecmerova

Synthesis of fluorinated acyclic nucleoside phosphonates with 5-azacytosine base moiety

TETRAHEDRON
2019 | Journal article
DOI: 10.1016/j.tet.2019.130529
Part of ISSN: 0040-4020
Part of ISSN: 1464-5416
Contributors: Pomeisl, Karel; Krecmerova, Marcela; Pohl, Radek; Snoeck, Robert; Andrei, Graciela
Source: Self-asserted source
Marcela Krecmerova

Utilization of 1,3-Dioxolanes in the Synthesis of α-branched Alkyl and Aryl 9-[2-(Phosphonomethoxy)Ethyl]Purines and Study of the Influence of α-branched Substitution for Potential Biological Activity

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
2019 | Journal article
DOI: 10.1080/15257770.2018.1506884
Part of ISSN: 1525-7770
Part of ISSN: 1532-2335
Contributors: Pomeisl, Karel; Pohl, Radek; Snoeck, Robert; Andrei, Graciela; Krecmerova, Marcela
Source: Self-asserted source
Marcela Krecmerova

Amino Acid Ester Prodrugs of Nucleoside and Nucleotide Antivirals

MINI-REVIEWS IN MEDICINAL CHEMISTRY
2017 | Journal article
DOI: 10.2174/1389557517666170216151601
Part of ISSN: 1389-5575
Part of ISSN: 1875-5607
Contributors: Krecmerova, Marcela
Source: Self-asserted source
Marcela Krecmerova

Cell-based DNA demethylation detection system for screening of epigenetic drugs in 2D, 3D, and xenograft models

CYTOMETRY PART A
2017 | Journal article
DOI: 10.1002/cyto.a.23004
Part of ISSN: 1552-4922
Part of ISSN: 1552-4930
Contributors: Agrawal, Khushboo; Das, Viswanath; Otmar, Miroslav; Krecmerova, Marcela; Dzubak, Petr; Hajduch, Marian
Source: Self-asserted source
Marcela Krecmerova

Investigation of the acid-base and electromigration properties of 5-azacytosine derivatives using capillary electrophoresis and density functional theory calculations

JOURNAL OF CHROMATOGRAPHY A
2017 | Journal article
DOI: 10.1016/j.chroma.2016.11.058
Part of ISSN: 0021-9673
Part of ISSN: 1873-3778
Contributors: Geffertova, Denisa; Ali, Syed Tahir; Solinova, Veronika and Krecmerova, Marcela; Holy, Antonin; Havlas, Zdenek; Kasicka, Vaclav
Source: Self-asserted source
Marcela Krecmerova

New prodrugs of two pyrimidine acyclic nucleoside phosphonates: Synthesis and antiviral activity

BIOORGANIC & MEDICINAL CHEMISTRY
2017 | Journal article
DOI: 10.1016/j.bmc.2017.06.046
Part of ISSN: 0968-0896
Part of ISSN: 1464-3391
Contributors: Krecmerova, Marcela; Dracinsky, Martin; Snoeck, Robert and Balzarini, Jan; Pomeisl, Karel; Andrei, Graciela
Source: Self-asserted source
Marcela Krecmerova

Discovery of orally available prodrugs of the GCPII inhibitor 2-phosphonomethyl pentanedioic acid (2-PMPA)

FASEB JOURNAL
2016 | Journal article
Part of ISSN: 0892-6638
Part of ISSN: 1530-6860
Contributors: Majer, Pavel; Jancarik, Andrej; Krecmerova, Marcela; Tichy, Tomas; Tenora, Lukas; Wozniak, Krystyna; Wu, Ying; Pommier, Elie; Ferraris, Dana V.; Rais, Rana et al.
Source: Self-asserted source
Marcela Krecmerova

Discovery of orally available prodrugs of the GCPII inhibitor 2-phosphonomethyl pentanedioic acid (2-PMPA)

FASEB JOURNAL
2016 | Journal article
Part of ISSN: 0892-6638
Part of ISSN: 1530-6860
Contributors: Majer, Pavel; Jancarik, Andrej; Krecmerova, Marcela; Tichy, Tomas; Tenora, Lukas; Wozniak, Krystyna; Wu, Ying; Pommier, Elie; Ferraris, Dana V.; Rais, Rana et al.
Source: Self-asserted source
Marcela Krecmerova

Discovery of Orally Available Prodrugs of the Glutamate Carboxypeptidase II (GCPII) Inhibitor 2-Phosphonomethylpentanedioic Acid (2-PMPA)

JOURNAL OF MEDICINAL CHEMISTRY
2016 | Journal article
DOI: 10.1021/acs.jmedchem.6b00062
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Majer, Pavel; Jancarik, Andrej; Krecmerova, Marcela; Tichy, Tomas; Tenora, Lukas; Wozniak, Krystyna; Wu, Ying; Pommier, Elie; Ferraris, Dana; Rais, Rana et al.
Source: Self-asserted source
Marcela Krecmerova

Molecular hallmarks of drug resistance to DNA methylation inhibitors and alternative therapeutic regimen for overcoming resistance

CANCER RESEARCH
2016 | Journal article
DOI: 10.1158/1538-7445.AM2016-4453
Part of ISSN: 0008-5472
Part of ISSN: 1538-7445
Contributors: Agrawal, Khushboo; Vojta, Petr; Holub, Dusan; Slavkovsky, Rastislav; Frydrych, Ivo; Dzubak, Petr; Krecmerova, Marcela and Hajduch, Marian
Source: Self-asserted source
Marcela Krecmerova

Novel and Efficient Synthesis of <i>gem</i>-Difluorinated Derivatives of Acyclic Nucleoside Phosphonates (ANPs)

CHEMISTRYSELECT
2016 | Journal article
DOI: 10.1002/slct.201600445
Part of ISSN: 2365-6549
Contributors: Pomeisl, Karel; Beier, Petr; Pohl, Radek; Krecmerova, Marcela
Source: Self-asserted source
Marcela Krecmerova

Novel lymphoid targeted prodrugs of the glutamine antagonist DON for the treatment of hematological malignancies

FASEB JOURNAL
2016 | Journal article
Part of ISSN: 0892-6638
Part of ISSN: 1530-6860
Contributors: Jancarik, Andrej; Rais, Rana; At, Jesse; Tenora, Lukas and Krecmerova, Marcela; Cheng, Chih; Pommier, Elie; Rojas, Camilo; Powel, Jonathan; Majer, Pavel; Slusher, Barbara
Source: Self-asserted source
Marcela Krecmerova

Novel lymphoid targeted prodrugs of the glutamine antagonist DON for the treatment of hematological malignancies

FASEB JOURNAL
2016 | Journal article
Part of ISSN: 0892-6638
Part of ISSN: 1530-6860
Contributors: Jancarik, Andrej; Rais, Rana; Alt, Jesse; Tenora, Lukas and Krecmerova, Marcela; Cheng, Chih; Pommier, Elie; Rojas, Camilo; Powell, Jonathan; Majer, Pavel; Slusher, Barbara
Source: Self-asserted source
Marcela Krecmerova

Resistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1

ONCOTARGET
2016 | Journal article
DOI: 10.18632/oncotarget.7006
Part of ISSN: 1949-2553
Contributors: Topalis, Dimitri; Nogueira, Tatiane C.; De Schutter, Tim; El Amri, Chahrazade; Krecmerova, Marcela; Naesens, Lieve and Balzarini, Jan; Andrei, Graciela; Snoeck, Robert
Source: Self-asserted source
Marcela Krecmerova

Regioselective Palmitoylation of 9-(2,3-Dihydroxy- propyl)adenine Catalyzed by a Glycopolymer-enzyme Conjugate

Molecules
2016-05 | Journal article
DOI: 10.3390/molecules21050648
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

5-azacytidine nucleosides and their derivatives: Molecular hallmarks of drug resistance & alternative therapeutic regimen

CANCER RESEARCH
2015 | Journal article
DOI: 10.1158/1538-7445.AM2015-2944
Part of ISSN: 0008-5472
Part of ISSN: 1538-7445
Contributors: Agrawal, Khushboo; Vojta, Petr; Holub, Dusan; Frydrych, Ivo and Dzubak, Petr; Otmar, Miroslav; Krecmerova, Marcela; Hajduch, Marian
Source: Self-asserted source
Marcela Krecmerova

5-azacytidine nucleosides and their derivatives: Molecular hallmarks of drug resistance

CANCER RESEARCH
2014 | Journal article
DOI: 10.1158/1538-7445.AM2014-400
Part of ISSN: 0008-5472
Part of ISSN: 1538-7445
Contributors: Agrawal, Khushboo; Dzubak, Petr; Frydrych, Ivo; Holub, Dusan; Vojta, Petr; Krecmerova, Marcela; Otmar, Miroslav; Hajduch, Marian
Source: Self-asserted source
Marcela Krecmerova

<i>N</i><SUP>4</SUP>-Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (<i>S</i>)-HPMP-5-azaC: Chemistry and antiviral activity

BIOORGANIC & MEDICINAL CHEMISTRY
2014 | Journal article
DOI: 10.1016/j.bmc.2014.03.031
Part of ISSN: 0968-0896
Part of ISSN: 1464-3391
Contributors: Krecmerova, Marcela; Pohl, Radek; Masojidkova, Milena and Balzarini, Jan; Snoeck, Robert; Andrei, Graciela
Source: Self-asserted source
Marcela Krecmerova

Enhancing of enzymatic palmitoylation of racemic 9-(2,3-dihydroxypropyl)adenine in co-solvent mixture as the reaction media

NEW BIOTECHNOLOGY
2014 | Journal article
DOI: 10.1016/j.nbt.2014.05.1787
Part of ISSN: 1871-6784
Part of ISSN: 1876-4347
Contributors: Brabcova, Jana; Blazek, Jiri; Krecmerova, Marcela; Zarevucka, Marie; Palomo, Jose M.
Source: Self-asserted source
Marcela Krecmerova

Transdermal Delivery and Cutaneous Targeting of Antivirals using a Penetration Enhancer and Lysolipid Prodrugs

PHARMACEUTICAL RESEARCH
2014 | Journal article
DOI: 10.1007/s11095-013-1228-8
Part of ISSN: 0724-8741
Part of ISSN: 1573-904X
Contributors: Diblikova, Denisa; Kopecna, Monika; Skolova, Barbora and Krecmerova, Marcela; Roh, Jaroslav; Hrabalek, Alexandr and Vavrova, Katerina
Source: Self-asserted source
Marcela Krecmerova

9-[2-(<i>R</i>)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (<i>R</i>)-PMPDAP and its prodrugs: Optimized preparation, including identification of by-products formed, and antiviral evaluation in vitro

BIOORGANIC & MEDICINAL CHEMISTRY
2013 | Journal article
DOI: 10.1016/j.bmc.2012.12.044
Part of ISSN: 0968-0896
Contributors: Krecmerova, Marcela; Jansa, Petr; Dracinsky, Martin; Sazelova, Petra; Kasicka, Vaclav; Neyts, Johan; Auwerx, Joeri; Kiss, Eleonora; Goris, Nesya; Stepan, George et al.
Source: Self-asserted source
Marcela Krecmerova

Evaluation of Novel Acyclic Nucleoside Phosphonates against Human and Animal Gammaherpesviruses Revealed an Altered Metabolism of Cyclic Prodrugs upon Epstein-Barr Virus Reactivation in P3HR-1 Cells

JOURNAL OF VIROLOGY
2013 | Journal article
DOI: 10.1128/JVI.02231-13
Part of ISSN: 0022-538X
Part of ISSN: 1098-5514
Contributors: Coen, Natacha; Duraffour, Sophie; Naesens, Lieve; Krecmerova, Marcela; Van den Oord, Joost; Snoeck, Robert; Andrei, Graciela
Source: Self-asserted source
Marcela Krecmerova

Inhibition of the <i>Escherichia coli</i> 6-Oxopurine Phosphoribosyltransferases by Nucleoside Phosphonates: Potential for New Antibacterial Agents

JOURNAL OF MEDICINAL CHEMISTRY
2013 | Journal article
DOI: 10.1021/jm400779n
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Keough, Dianne T.; Hockova, Dana; Rejman, Dominik; Spacek, Petr; Vrbkova, Silvie; Krecmerova, Marcela; Eng, Wai Soon; Jans, Harmen; West, Nicholas P.; Naesens, Lieve M. J. et al.
Source: Self-asserted source
Marcela Krecmerova

5-azacytosine compounds in medicinal chemistry: current stage and future perspectives

FUTURE MEDICINAL CHEMISTRY
2012 | Journal article
DOI: 10.4155/FMC.12.36
Part of ISSN: 1756-8919
Part of ISSN: 1756-8927
Contributors: Krecmerova, Marcela; Otmar, Miroslav
Source: Self-asserted source
Marcela Krecmerova

An enzymatic glycosylation of nucleoside analogues using β-galactosidase from <i>Escherichia coli</i>

BIOORGANIC & MEDICINAL CHEMISTRY
2012 | Journal article
DOI: 10.1016/j.bmc.2012.02.062
Part of ISSN: 0968-0896
Part of ISSN: 1464-3391
Contributors: Blazek, Jiri; Jansa, Petr; Baszczynski, Ondrej; Kaiser, Martin Maxmilian; Otmar, Miroslav; Krecmerova, Marcela; Drancinsky, Martin; Holy, Antonin; Kralova, Blanka
Source: Self-asserted source
Marcela Krecmerova

Lipases as Tools in the Synthesis of Prodrugs from Racemic 9-(2,3-Dihydroxypropyl)adenine

MOLECULES
2012 | Journal article
DOI: 10.3390/molecules171213813
Part of ISSN: 1420-3049
Contributors: Brabcova, Jana; Blazek, Jiri; Janska, Lucie; Krecmerova, Marcela; Zarevucka, Marie
Source: Self-asserted source
Marcela Krecmerova

Mutations Conferring Resistance to Viral DNA Polymerase Inhibitors in Camelpox Virus Give Different Drug-Susceptibility Profiles in Vaccinia Virus

JOURNAL OF VIROLOGY
2012 | Journal article
DOI: 10.1128/JVI.00355-12
Part of ISSN: 0022-538X
Part of ISSN: 1098-5514
Contributors: Duraffour, Sophie; Andrei, Graciela; Topalis, Dimitri and Krecmerova, Marcela; Crance, Jean-Marc; Garin, Daniel; Snoeck, Robert
Source: Self-asserted source
Marcela Krecmerova

SYNTHESES OF 1-[2-(PHOSPHONOMETHOXY)ALKYL]THYMINE MONOPHOSPHATES AND AN EVALUATION OF THEIR INHIBITORY ACTIVITY TOWARD HUMAN THYMIDINE PHOSPHORYLASE

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
2012 | Journal article
DOI: 10.1080/15257770.2011.648361
Part of ISSN: 1525-7770
Part of ISSN: 1532-2335
Contributors: Pomeisl, Karel; Horska, Kvetoslava; Pohl, Radek; Blazek, Jiri; Krecmerova, Marcela
Source: Self-asserted source
Marcela Krecmerova

Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (<i>S</i>)-HPMP or PEE acyclic moiety

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2012 | Journal article
DOI: 10.1016/j.ejmech.2012.07.027
Part of ISSN: 0223-5234
Contributors: Tichy, Tomas; Andrei, Graciela; Snoeck, Robert; Balzarini, Jan; Dracinsky, Martin; Krecmerova, Marcela
Source: Self-asserted source
Marcela Krecmerova

Synthesis of purine <i>N</i><SUP>9</SUP>-[2-hydroxy-3-<i>O</i>-(phosphonomethoxy)propyl] derivatives and their side-chain modified analogs as potential antimalarial agents

BIOORGANIC & MEDICINAL CHEMISTRY
2012 | Journal article
DOI: 10.1016/j.bmc.2011.12.034
Part of ISSN: 0968-0896
Contributors: Krecmerova, Marcela; Dracinsky, Martin; Hockova, Dana; Holy, Antonin; Keough, Dianne T.; Guddat, Luke W.
Source: Self-asserted source
Marcela Krecmerova

8-Aza-7,9-dideazaxanthine acyclic nucleoside phosphonate inhibitors of thymidine phosphorylase

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
2011 | Journal article
DOI: 10.1016/j.bmcl.2010.12.027
Part of ISSN: 0960-894X
Part of ISSN: 1464-3405
Contributors: Marak, David; Otmar, Miroslav; Votruba, Ivan; Dracinsky, Martin; Krecmerova, Marcela
Source: Self-asserted source
Marcela Krecmerova
grade
Preferred source (of 2)‎

Activities of Different Classes of Acyclic Nucleoside Phosphonates against BK Virus in Primary Human Renal Cells

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
2011 | Journal article
DOI: 10.1128/AAC.01809-10
Part of ISSN: 0066-4804
Part of ISSN: 1098-6596
Contributors: Topalis, D.; Lebeau, I.; Krecmerova, M.; Andrei, G.; Snoeck, R.
Source: Self-asserted source
Marcela Krecmerova

Amido tyrosine esters: a promising new approach to antiviral nucleoside phosphonate prodrugs

ANTIVIRAL RESEARCH
2011 | Journal article
DOI: 10.1016/j.antiviral.2011.03.009
Part of ISSN: 0166-3542
Contributors: McKenna, Charles E.; Kashemirov, Boris A.; Zakharova, Valeria M.; Krylov, Ivan S.; Williams, Melissa; Krecmerova, Marcela and Drach, John C.; Hilfinger, John M.
Source: Self-asserted source
Marcela Krecmerova

New prodrugs of Adefovir and Cidofovir

BIOORGANIC & MEDICINAL CHEMISTRY
2011 | Journal article
DOI: 10.1016/j.bmc.2011.04.016
Part of ISSN: 0968-0896
Contributors: Tichy, Tomas; Andrei, Graciela; Dracinsky, Martin; Holy, Antonin; Balzarini, Jan; Snoeck, Robert; Krecmerova, Marcela
Source: Self-asserted source
Marcela Krecmerova

SYNTHESIS OF <i>O</i><SUP>2</SUP>- AND <i>N</i><SUP>3</SUP>-(2-PHOSPHONOMETHOXY)ETHYL DERIVATIVES OF 6-PHENYL- AND 6-PYRIDINYL-5-AZACYTOSINE

HETEROCYCLES
2011 | Journal article
DOI: 10.3987/COM-11-12137
Part of ISSN: 0385-5414
Part of ISSN: 1881-0942
Contributors: Otmar, Miroslav; Dracinsky, Martin; Krecmerova, Marcela and Balzarini, Jan; Andrei, Graciela; Snoeck, Robert
Source: Self-asserted source
Marcela Krecmerova
grade
Preferred source (of 2)‎

<i>Plasmodium vivax</i> hypoxanthine-guanine phosphoribosyltransferase: A target for anti-malarial chemotherapy

MOLECULAR AND BIOCHEMICAL PARASITOLOGY
2010 | Journal article
DOI: 10.1016/j.molbiopara.2010.05.018
Part of ISSN: 0166-6851
Part of ISSN: 1872-9428
Contributors: Keough, Dianne T.; Hockova, Dana; Krecmerova, Marcela; Cesnek, Michal; Holy, Antonin; Naesens, Lieve; Brereton, Ian M. and Winzor, Donald J.; de Jersey, John; Guddat, Luke W.
Source: Self-asserted source
Marcela Krecmerova
grade
Preferred source (of 2)‎

Acyclic nucleoside phosphonates with 5-azacytosine base moiety substituted in C-6 position

BIOORGANIC & MEDICINAL CHEMISTRY
2010 | Journal article
DOI: 10.1016/j.bmc.2009.10.044
Part of ISSN: 0968-0896
Contributors: Krecmerova, Marcela; Masojidkova, Milena; Holy, Antonin
Source: Self-asserted source
Marcela Krecmerova
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