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Employment (1)

University of Texas Health Science Center at Houston: Houston, TX, US

Employment
Source: Self-asserted source
Lei Zheng

Education and qualifications (3)

University of Bern: Bern, CH

1999 to 2003 | PhD (Chemistry and Biochemistry)
Education
Source: Self-asserted source
Lei Zheng

Shandong University: Jinan, Shandong, CN

1994 to 1997 | Master of Science (Microbiology)
Education
Source: Self-asserted source
Lei Zheng

Shandong University: Jinan, Shandong, CN

1990-09 to 1994-06 | Bachelor of Science (Microbiology)
Education
Source: Self-asserted source
Lei Zheng

Professional activities (1)

American Society for Biochemistry and Molecular Biology: Rockville, MD, US

Membership
Source: Self-asserted source
Lei Zheng

Funding (2)

Structure and function of a metabolic pacemaker in bacterial cell membrane

2021-08-01 to 2025-06-30 | Grant
National Institute of General Medical Sciences (Bethesda, US)
GRANT_NUMBER: R01GM143418
Source: Self-asserted source
Lei Zheng via DimensionsWizard

Elucidating structural basis of sodium/calcium exchanger NCX essential for cardiac contractability

2018-07-01 to 2021-06-30 | Grant
American Heart Association (Dallas, US)
GRANT_NUMBER:

18TPA34230046

Source: Self-asserted source
Lei Zheng via DimensionsWizard

Works (14)

Structures of channelrhodopsin paralogs in peptidiscs explain their contrasting K+ and Na+ selectivities

Nature Communications
2023-07-20 | Journal article
Contributors: Takefumi Morizumi; Kyumhyuk Kim; Hai Li; Elena G. Govorunova; Oleg A. Sineshchekov; Yumei Wang; Lei Zheng; Éva Bertalan; Ana-Nicoleta Bondar; Azam Askari et al.
Source: check_circle
Crossref

Ca2+ efflux facilitated by co-transport of inorganic phosphate anion in the H+/Ca2+ antiporter YfkE

Communications Biology
2023-05-29 | Journal article
Contributors: Wei Niu; Wenchang Zhou; Shuo Lu; Trung Vu; Vasanthi Jayaraman; José D. Faraldo-Gómez; Lei Zheng
Source: check_circle
Crossref

The crystal structure of bromide-bound GtACR1 reveals a pre-activated state in the transmembrane anion tunnel

eLife
2021-05-17 | Journal article
Contributors: Hai Li; Chia-Ying Huang; Elena G Govorunova; Oleg A Sineshchekov; Adrian Yi; Kenneth J Rothschild; Meitian Wang; Lei Zheng; John L Spudich
Source: check_circle
Crossref

The Crystal Structure of Bromide-BoundGtACR1 Reveals a Pre-Activated State in the Transmembrane Anion Tunnel

2021-01-02 | Preprint
Contributors: Hai Li; Chia-Ying Huang; Elena G. Govorunova; Oleg A. Sineshchekov; Meitian Wang; Lei Zheng; John L. Spudich
Source: check_circle
Crossref

Intracellular Ca 2+ regulation of H + /Ca 2+ antiporter YfkE mediated by a Ca 2+ mini-sensor

Proceedings of the National Academy of Sciences
2020-05-12 | Journal article
Contributors: Shuo Lu; Zhenlong Li; Alemayehu A. Gorfe; Lei Zheng
Source: check_circle
Crossref

Crystal structure of a natural light-gated anion channelrhodopsin

eLife
2019-01-07 | Journal article
Contributors: Hai Li; Chia-Ying Huang; Elena G Govorunova; Christopher T Schafer; Oleg A Sineshchekov; Meitian Wang; Lei Zheng; John L Spudich
Source: check_circle
Crossref

A dual substrate-accessing mechanism of a major facilitator superfamily protein facilitates lysophospholipid flipping across the cell membrane

Journal of Biological Chemistry
2018-12 | Journal article
Contributors: Yibin Lin; R.N.V. Krishna Deepak; Jonathan Zixiang Zheng; Hao Fan; Lei Zheng
Source: check_circle
Crossref

The phospholipid-repair system LplT/Aas in Gram-negative bacteria protects the bacterial membrane envelope from host phospholipase A<sub>2</sub> attack.

The Journal of biological chemistry
2018-01-18 | Journal article
Contributors: Lin Y; Bogdanov M; Lu S; Guan Z; Margolin W; Jerrold Weiss; Zheng L
Source: Self-asserted source
Lei Zheng

Biogenesis, transport and remodeling of lysophospholipids in Gram-negative bacteria.

Biochimica et biophysica acta. Molecular and cell biology of lipids
2016-12-09 | Journal article
Contributors: Zheng L; Lin Y; Lu S; Zhang J; Bogdanov M
Source: Self-asserted source
Lei Zheng

Structural Insight into Substrate Selection and Catalysis of Lipid Phosphate Phosphatase PgpB in the Cell Membrane.

The Journal of biological chemistry
2016-07-12 | Journal article
Contributors: Tong S; Lin Y; Lu S; Wang M; Bogdanov M; Zheng L
Source: Self-asserted source
Lei Zheng

Substrate Selectivity of Lysophospholipid Transporter LplT Involved in Membrane Phospholipid Remodeling in Escherichia coli.

The Journal of biological chemistry
2015-11-26 | Journal article
Contributors: Lin Y; Bogdanov M; Tong S; Guan Z; Zheng L
Source: Self-asserted source
Lei Zheng

Crystal structure of Ca2+/H+ antiporter protein YfkE reveals the mechanisms of Ca2+ efflux and its pH regulation.

Proceedings of the National Academy of Sciences of the United States of America
2013-06-24 | Journal article
Contributors: Wu M; Tong S; Waltersperger S; Diederichs K; Wang M; Zheng L
Source: Self-asserted source
Lei Zheng

The mechanism of ammonia transport based on the crystal structure of AmtB of Escherichia coli

Proceedings of the National Academy of Sciences
2004-12-07 | Journal article
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Lei Zheng

An efficient one-step site-directed and site-saturation mutagenesis protocol

Nucleic Acids Research
2004-08-03 | Journal article
Part of ISSN: 1362-4962
Source: Self-asserted source
Lei Zheng

Peer review (1 review for 1 publication/grant)

Review activity for Nature communications (1)