Personal information

Poland

Activities

Employment (1)

Medical University of Silesia: Katowice, PL

1999-07-01 to present | PhD (Department of Biopharmacy)
Employment
Source: Self-asserted source
Arkadiusz Orchel

Education and qualifications (1)

University of Silesia: Katowice, PL

1993-10-01 to 1998-09-30 | MSc (Faculty of Biology and Environmental Protection)
Education
Source: Self-asserted source
Arkadiusz Orchel

Works (50 of 119)

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Page 1 of 3

Antiproliferative and Cytotoxic Properties of Propynoyl Betulin Derivatives against Human Ovarian Cancer Cells: In Vitro Studies

International Journal of Molecular Sciences
2023-11-18 | Journal article
Contributors: Ewa Chodurek; Arkadiusz Orchel; Paweł Gwiazdoń; Anna Kaps; Piotr Paduszyński; Marzena Jaworska-Kik; Elwira Chrobak; Ewa Bębenek; Stanisław Boryczka; Janusz Kasperczyk
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Bioresorbable Nonwoven Patches as Taxane Delivery Systems for Prostate Cancer Treatment

Pharmaceutics
2022-12-17 | Journal article
Contributors: Joanna Jaworska; Arkadiusz Orchel; Anna Kaps; Marzena Jaworska-Kik; Anna Hercog; Mateusz Stojko; Jakub Włodarczyk; Monika Musiał-Kulik; Małgorzata Pastusiak; Marcelina Bochenek et al.
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Synthesis of the Bacteriostatic Poly(l-Lactide) by Using Zinc (II)[(acac)(L)H2O] (L = Aminoacid-Based Chelate Ligands) as an Effective ROP Initiator

International Journal of Molecular Sciences
2021-06-28 | Journal article
Contributors: Renata Barczyńska-Felusiak; Małgorzata Pastusiak; Piotr Rychter; Bożena Kaczmarczyk; Michał Sobota; Andrzej Wanic; Anna Kaps; Marzena Jaworska-Kik; Arkadiusz Orchel; Piotr Dobrzyński
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Anticancer Activity of the Acetylenic Derivative of Betulin Phosphate Involves Induction of Necrotic-Like Death in Breast Cancer Cells In Vitro

Molecules
2021-01-25 | Journal article
Contributors: Arkadiusz Orchel; Ewa Chodurek; Marzena Jaworska-Kik; Piotr Paduszyński; Anna Kaps; Elwira Chrobak; Ewa Bębenek; Stanisław Boryczka; Paulina Borkowska; Janusz Kasperczyk
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Bioactive (Co)oligoesters as Potential Delivery Systems of p-Anisic Acid for Cosmetic Purposes

Materials
2020-09-18 | Journal article
Contributors: Magdalena Martinka Maksymiak; Magdalena Zięba; Arkadiusz Orchel; Monika Musiał-Kulik; Marek Kowalczuk; Grazyna Adamus
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Biodegradable Electrospun Nonwovens Releasing Propolis as a Promising Dressing Material for Burn Wound Treatment

Pharmaceutics
2020-09-17 | Journal article
Contributors: Mateusz Stojko; Jakub Włodarczyk; Michał Sobota; Paulina Karpeta-Jarząbek; Małgorzata Pastusiak; Henryk Janeczek; Piotr Dobrzyński; Gabriela Starczynowska; Arkadiusz Orchel; Jerzy Stojko et al.
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Electrochemical and Biological Performance of Biodegradable Polymer Coatings on Ti6Al7Nb Alloy

Materials
2020-04-09 | Journal article
Contributors: Wojciech Kajzer; Janusz Szewczenko; Anita Kajzer; Marcin Basiaga; Marcin Kaczmarek; Magdalena Antonowicz; Joanna Jaworska; Katarzyna Jelonek; Arkadiusz Orchel; Katarzyna Nowińska et al.
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Antiproliferative and proapoptotic activity of ursolic acid in human skin malignant melanoma cells.

Post.Hig.Med.Dośw. (Online)/Adv.Hyg.Exp.Med. (Online)
2018 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Bioresorbable filomicelles for targeted delivery of betulin derivative - in vitro study.

Int.J.Pharm.
2018 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Combined action of paclitaxel and betulin on SK-OV-3 ovarian cancer cells line.

3rd International Conference of Cell Biology, Kraków 26-27.05.2017, book of abstracts
2017 | Book chapter
Source: Self-asserted source
Arkadiusz Orchel

Effect of polymer degradation on prolonged release of paclitaxel from filomicelles of polylactide/poly(ethylene glycol) block copolymers.

Mater.Sci.Eng.C - Mater.Biol.Appl.
2017 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

New betulin derivatives as candidates for anticancer agents.

6th Central European Congress of Life Sciences Eurobiotech, [Kraków] 11-14.09.2017. Program and abstract book.
2017 | Book chapter
Source: Self-asserted source
Arkadiusz Orchel

The synthesis and structural characterization of graft copolymers composed of γ-PGA backbone and oligoesters pendant chains.

J.Am.Soc.Mass.Spectrom.
2017 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Influence of 28-O-propynoylbetulin on proliferation and apoptosis of melanotic and amelanotic human melanoma cells.

Post.Hig.Med.Dośw. (Online)/Adv.Hyg.Exp.Med. (Online)
2016 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Multidrug PLA-PEG filomicelles for concurrent delivery of anticancer drugs-The influence of drug-drug and drug-polymer interactions on drug loading and release properties.

Int.J.Pharm.
2016 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Single and multidrug filomicelles as anticancer drug delivery system.

Inż.Biomater. / Eng.Biomater.
2016 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Zastosowanie kwasu traneksamowego w leczeniu przebarwień związanych z ostudą.

Dermatol.Estet.
2016 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Antiproliferative activity of novel acetylenic derivatives of betulin against G-363 human melanoma cells.

Acta Pol.Pharm.-Drug Res.
2015 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Designing of biodegradable and biocompatible release and delivery systems of selected antioxidants used in cosmetology.

Biomacromolecules
2015 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Scaffolds with shape memory behavior for the treatment of large bone defects.

J.Biomed.Mater.Res. A
2015 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Antiproliferative activity of novel acetylenic derivatives of betulin against G-361 human melanoma cells.

9th Multidisciplinary Conference on Drug Research - MKNOL 2014, Szydłów 12-14.05.2014, book of abstracts
2014 | Book chapter
Source: Self-asserted source
Arkadiusz Orchel

Antiproliferative and apoptotic effects of valproic acid in human melanoma cells.

9th Multidisciplinary Conference on Drug Research - MKNOL 2014, Szydłów 12-14.05.2014, book of abstracts
2014 | Book chapter
Source: Self-asserted source
Arkadiusz Orchel

Degradation process of L-lactide/glycolide/trimethylene carbonate terpolymer in cell culture environment.

9th Multidisciplinary Conference on Drug Research - MKNOL 2014, Szydłów 12-14.05.2014, book of abstracts
2014 | Book chapter
Source: Self-asserted source
Arkadiusz Orchel

Effect of valproic acid on the proliferation and apoptosis of the human melanoma G-361 cell line.

Acta Pol.Pharm.-Drug Res.
2014 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Histone H3 expression - a potential cell proliferation marker for molecular pharmacology.

9th Multidisciplinary Conference on Drug Research - MKNOL 2014, Szydłów 12-14.05.2014, book of abstracts
2014 | Book chapter
Source: Self-asserted source
Arkadiusz Orchel

Influence of betulin and 28-O-propynoylbetulin on proliferation and apoptosis of human melanoma cells (G-361)*.

Post.Hig.Med.Dośw. (Online)/Adv.Hyg.Exp.Med. (Online)
2014 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Aktywność proliferacyjna chondrocytów rosnących na rusztowaniach polimerowych z pamięcią kształtu.

Konferencja Naukowa - "Polimery z pamięcią kształtu w medycynie i farmacji", Targanice k. Andrychowa 23-25.09.2013, streszczenia
2013 | Book chapter
Source: Self-asserted source
Arkadiusz Orchel

Comparison of methods for proliferative activity assessment in chondrocyte spatial cell cultures.

Acta Biochim.Pol.
2013 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Influence of HDAC inhibitor on proliferative status of human osteoblasts and fibroblasts.

4 Polski Kongres Genetyki, Poznań 10-13.09.2013, streszczenia
2013 | Book chapter
Source: Self-asserted source
Arkadiusz Orchel

Role of protein tyrosine kinase in the effect of IP6 on IL-8 secretion in intestinal epithelial cells.

Acta Pol.Pharm.-Drug Res.
2013 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

The effect of histone deacetylase inhibitor on expression levels of histone H3/f.

Acta Biochim.Pol.
2013 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

The effect of sodium butyrate and sodium valproate acid on proliferative activity of human melanoma cells.

4 Polski Kongres Genetyki, Poznań 10-13.09.2013, streszczenia
2013 | Book chapter
Source: Self-asserted source
Arkadiusz Orchel

The influence of chain microstructure of biodegradable copolyesters obtained with low-toxic zirconium initiator to in vitro biocompatibility.

Biomed Res.Int.
2013 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Wstępna ocena oddziaływania simwastatyny na przestrzenne hodowle chondrocytów.

Konferencja Naukowa - "Polimery z pamięcią kształtu w medycynie i farmacji", Targanice k. Andrychowa 23-25.09.2013, streszczenia
2013 | Book chapter
Source: Self-asserted source
Arkadiusz Orchel

Biocompatibility of L-lactide-co-glycolide-co-trimethylene-carbonate shape memory terpolymer with human chondrocytes.

Inż.Biomater. / Eng.Biomater.
2012 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Comparison of changes in expression levels of β-tubulin and histone H3/f as cell proliferation markers in human fibroblast cell cultures.

Acta Biochim.Pol.
2012 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Effect of valproic acid and cisplatin on the proliferation of tumor cell lines A375 and C32.

8th Multidisciplinary Conference on Drug Research - MKNOL 2012, Rawa Mazowiecka 30.05-1.06.2012, book of abstracts.
2012 | Book chapter
Source: Self-asserted source
Arkadiusz Orchel

Evaluation of melanogenesis in A-375 cells in the presence of DMSO and analysis of pyrolytic profile of isolated melanin.

Sci.World J./TheScientificWorldJOURNAL
2012 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Evaluation of melanogenesis in A-375 melanoma cells treated with 5,7-dimethoxycoumarin and valproic acid.

Cell.Mol.Biol.Lett.
2012 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Expression pattern of histone H3 subtypes in articular chondrocytes.

Inż.Biomater. / Eng.Biomater.
2012 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Phytic acid down-regulates IL-8 secretion from colonic epithelial cells by influencing mitogen-avtivated protein kinase signaling pathway.

Acta Pol.Pharm.-Drug Res.
2012 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Phytic acid down-regulates IL-8 secretion from IL-1β stimulated colonic epithelial cells by influencing mitogen-activated protein kinase signaling pathway.

8th Multidisciplinary Conference on Drug Research - MKNOL 2012, Rawa Mazowiecka 30.05-1.06.2012, book of abstracts.
2012 | Book chapter
Source: Self-asserted source
Arkadiusz Orchel

The effect of histone deacetylase inhibitor on expression levels of histone H3/f.

Acta Biochim.Pol.
2012 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Valproic acid enhances cisplatin cytotoxicity in melanoma cells.

Acta Pol.Pharm.-Drug Res.
2012 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Znaczenie epigenetyki w patogenezie czerniaka.

Ann.Acad.Med.Siles.
2012 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

A histone H3/a as a new proliferative marker for tissue engineering research.

Acta Biochim.Pol.
2011 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Biocompatibility of L-lactide-co-glycolide-co-trimethylene-carbonate shape memory terpolymer with human chondrocytes.

France-Poland Seminar on Polymeric Biomaterials for Therapeutic Applications. Montpellier [France], 17-18.11.2011. Program and book of abstracts.
2011 | Book chapter
Source: Self-asserted source
Arkadiusz Orchel

Biocompatibility of poly (ε-caprolactone-co-trimethylene carbonate) with human chondrocytes - in vitro studies.

France-Poland Seminar on Polymeric Biomaterials for Therapeutic Applications. Montpellier [France], 17-18.11.2011. Program and book of abstracts.
2011 | Book chapter
Source: Self-asserted source
Arkadiusz Orchel

Changes in mRNA levels of histone H3/a and p150 of CAF-1 as a marker of cell proliferation.

Acta Biochim.Pol.
2011 | Journal article
Source: Self-asserted source
Arkadiusz Orchel

Expression pattern of histone H3 subtypes in articular chondrocytes.

France-Poland Seminar on Polymeric Biomaterials for Therapeutic Applications. Montpellier [France], 17-18.11.2011. Program and book of abstracts.
2011 | Book chapter
Source: Self-asserted source
Arkadiusz Orchel
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