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Pharmacogenomics, Personalized Medicine, Precision medicine, Clinical pharmacy, Mood disorder

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Employment (1)

National Cheng Kung University: Tainan City, TW

2023-08-01 to present | Professor (School of Pharmacy & Institute of Clinical Pharmacy and Pharmaceutical Sciences)
Employment
Source: Self-asserted source
Hui Hua Chang

Works (44)

Peripheral inflammation is associated with impaired sadness recognition in euthymic bipolar patients

Journal of Psychiatric Research
2024-05 | Journal article
Contributors: Chih-Yu Chang; Hui Hua Chang; Cheng Ying Wu; Ying Tsung Tsai; Tsung-Hua Lu; Wei Hung Chang; Chia-Fen Hsu; Po See Chen; Huai-Hsuan Tseng
Source: check_circle
Crossref

A Selective Histone Deacetylase Inhibitor Induces Autophagy and Cell Death via SCNN1A Downregulation in Glioblastoma Cells.

Cancers
2022-09-19 | Journal article | Author
Contributors: Hui Hua Chang; Chang YY; Tsai BC; Chen LJ; Chang AC; Jian-Ying Chuang; Gean PW; Yuan-Shuo Hsueh
Source: Self-asserted source
Hui Hua Chang
grade
Preferred source (of 3)‎

A Longitudinal Study of the Association between the LEPR Polymorphism and Treatment Response in Patients with Bipolar Disorder

International Journal of Molecular Sciences
2022-08-25 | Journal article
Contributors: Hui Hua Chang; Yuan-Shuo Hsueh; Yung Wen Cheng; Huai-Hsuan Tseng
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Mitochondrial DNA Copy Number Is Associated With Treatment Response and Cognitive Function in Euthymic Bipolar Patients Receiving Valproate.

The international journal of neuropsychopharmacology
2022-08-01 | Journal article
Contributors: Chang CC; Chen PS; Lin JR; Chen YA; Liu CS; Lin TT; Chang HH
Source: Self-asserted source
Hui Hua Chang

Intraovarian Injection of Recombinant Human Follicle-Stimulating Hormone for Luteal-Phase Ovarian Stimulation during Oocyte Retrieval Is Effective in Women with Impending Ovarian Failure and Diminished Ovarian Reserve.

Biomedicines
2022-06-03 | Journal article | Author
Contributors: Chao Chin Hsu; Hsu I; Lee LH; Yuan-Shuo Hsueh; Chih-Ying Lin; Hui Hua Chang
Source: Self-asserted source
Hui Hua Chang
grade
Preferred source (of 3)‎

Predicting the Treatment Outcomes of Antidepressants Using a Deep Neural Network of Deep Learning in Drug-Naïve Major Depressive Patients.

Journal of personalized medicine
2022-04-26 | Journal article | Author
Contributors: Tsai PL; Hui Hua Chang; Po See Chen
Source: Self-asserted source
Hui Hua Chang
grade
Preferred source (of 3)‎

Ovarian Follicular Growth through Intermittent Vaginal Gonadotropin Administration in Diminished Ovarian Reserve Women.

Pharmaceutics
2022-04-15 | Journal article | Author
Contributors: Chao Chin Hsu; Hsu I; Lee LH; Hsu R; Yuan-Shuo Hsueh; Chih-Ying Lin; Hui Hua Chang
Source: Self-asserted source
Hui Hua Chang
grade
Preferred source (of 3)‎

Associations of emotion recognition, loneliness, and social functioning in euthymic patients with bipolar disorder.

The Kaohsiung journal of medical sciences
2022-04-08 | Journal article
Contributors: Lee CN; Huang YL; Chang HH; Kuo CY; Lu TH; Hsieh YT; Chang WH; Yen Kuang Yang; Po See Chen; Huai-Hsuan Tseng
Source: Self-asserted source
Hui Hua Chang

Extended Injection Intervals of Gonadotropins by Intradermal Administration in IVF Treatment.

The Journal of clinical endocrinology and metabolism
2022-01-01 | Journal article
Contributors: Chao Chin Hsu; Hsu I; Chang HH; Hsu R; Dorjee S
Source: Self-asserted source
Hui Hua Chang

Roles of C-reactive protein polymorphisms and life event changes on cognitive function in bipolar patients receiving valproate.

International journal of immunopathology and pharmacology
2022-01-01 | Journal article | Author
Contributors: Chen PS; Tang LY; Hui Hua Chang
Source: Self-asserted source
Hui Hua Chang
grade
Preferred source (of 2)‎

Differentially Expressed Genes Correlated with Fibrosis in a Rat Model of Chronic Partial Bladder Outlet Obstruction

Processes
2021-12-09 | Journal article
Contributors: Yuan-Shuo Hsueh; Hui Hua Chang; Shun-Yao Ko; Yi-Pai Lin; Wei-Yu Lin
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Ovarian Folliculogenesis and Uterine Endometrial Receptivity after Intermittent Vaginal Injection of Recombinant Human Follicle-Stimulating Hormone in Infertile Women Receiving In Vitro Fertilization and in Immature Female Rats.

International journal of molecular sciences
2021-10-05 | Journal article | Author
Contributors: Chao Chin Hsu; Hsu L; Yuan-Shuo Hsueh; Chih-Ying Lin; Hui Hua Chang; Hsu CT
Source: Self-asserted source
Hui Hua Chang
grade
Preferred source (of 3)‎

Association between the Serum Coenzyme Q10 Level and Seizure Control in Patients with Drug-Resistant Epilepsy.

Healthcare (Basel, Switzerland)
2021-08-28 | Journal article | Author
Contributors: Wei-Chen Liao; Chin-Wei Huang; Hsiao YH; Pi-shan Sung; Fu TF; Chang AYW; Hui Hua Chang
Source: Self-asserted source
Hui Hua Chang
grade
Preferred source (of 3)‎

Peripheral insulin sensitivity predicting cognitive function in euthymic bipolar disorder patients.

CNS spectrums
2021-03-11 | Journal article
Contributors: Chang HH; Tseng HH; Chang WH; Huang KC; Lu TH; Yen Kuang Yang; Po See Chen
Source: Self-asserted source
Hui Hua Chang

Changes in striatal dopamine transporters in bipolar disorder and valproate treatment.

European psychiatry : the journal of the Association of European Psychiatrists
2021-01-08 | Journal article
Contributors: Yuan-Shuo Hsueh; Lin CY; Chiu NT; Yang YK; Chen PS; Chang HH
Source: Self-asserted source
Hui Hua Chang

Childhood neglect is associated with corticostriatal circuit dysfunction in bipolar disorder adults.

Psychiatry research
2020-11-04 | Journal article
Contributors: Hsieh YT; Wu R; Tseng HH; Wei SY; Huang MC; Chang HH; Yang YK; Chen PS
Source: Self-asserted source
Hui Hua Chang

The social cognitive ability in Han Chinese euthymic patients with bipolar I and bipolar II disorder.

Journal of the Formosan Medical Association
2020-10-23 | Journal article
Contributors: Liu YC; Tseng HH; Chang YH; Chang HH; Yang YK; Chen PS
Source: Self-asserted source
Hui Hua Chang

Increased leptin-b expression and metalloprotease expression contributed to the pyridoxine-associated toxicity in zebrafish larvae displaying seizure-like behavior.

Biochemical pharmacology
2020-10-17 | Journal article
Contributors: Chen PY; Tsai YW; Chang AY; Chang HH; Hsiao YH; Huang CW; Sung PS; Chen BH; Fu TF
Source: Self-asserted source
Hui Hua Chang

Peripheral inflammation is associated with dysfunctional corticostriatal circuitry and executive dysfunction in bipolar disorder patients.

Brain, behavior, and immunity
2020-09-17 | Journal article
Contributors: Tseng HH; Chang HH; Wei SY; Lu TH; Hsieh YT; Yang YK; Chen PS
Source: Self-asserted source
Hui Hua Chang

Dysregulation of oxytocin and dopamine in the corticostriatal circuitry in bipolar II disorder.

Translational psychiatry
2020-08-12 | Journal article | Author
Contributors: Wei SY; Huai-Hsuan Tseng; Hui Hua Chang; Lu TH; Chang WH; Chiu NT; Yang YK; Po See Chen
Source: Self-asserted source
Hui Hua Chang
grade
Preferred source (of 2)‎

An Open Pilot Study of the Effect and Tolerability of Add-On Multivitamin Therapy in Patients with Intractable Focal Epilepsy.

Nutrients
2020-08-07 | Journal article | Author
Contributors: Hui Hua Chang; Sung PS; Liao WC; Chang AYW; Hsiao YH; Fu TF; Huang CY; Chin-Wei Huang
Source: Self-asserted source
Hui Hua Chang
grade
Preferred source (of 3)‎

The OXTR Polymorphism Stratified the Correlation of Oxytocin and Glucose Homeostasis in Non-Diabetic Subjects.

Diabetes, metabolic syndrome and obesity : targets and therapy
2019-12-19 | Journal article
Contributors: Chang HH; Chang WH; Chi MH; Peng YC; Huang CC; Yang YK; Po See Chen
Source: Self-asserted source
Hui Hua Chang

The Interaction of Oxytocin and Social Support, Loneliness, and Cortisol Level in Major Depression.

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology
2019-11-01 | Journal article | Author
Contributors: Tsung-Yu Tsai; Huai-Hsuan Tseng; Chi MH; Hui Hua Chang; Wu CK; Yang YK; Chen PS
Source: Self-asserted source
Hui Hua Chang
grade
Preferred source (of 2)‎

Nuclear KIT induces a NFKBIB-RELA-KIT autoregulatory loop in imatinib-resistant gastrointestinal stromal tumors.

Oncogene
2019-07-30 | Journal article
Contributors: Yuan-Shuo Hsueh; Chang HH; Shan YS; Sunny Sun; Fletcher JA; Chien-Feng Li; Chen LT
Source: Self-asserted source
Hui Hua Chang

Association between Polymorphisms of OCT1 and Metabolic Response to Metformin in Women with Polycystic Ovary Syndrome.

International journal of molecular sciences
2019-04-07 | Journal article
Contributors: Chang HH; Yuan-Shuo Hsueh; Cheng YW; Ou HT; Wu MH
Source: Self-asserted source
Hui Hua Chang
grade
Preferred source (of 2)‎

Factors related to metabolic parameters in medicated patients with major depressive disorder--a naturalistic study.

Psychiatry research
2018-06-30 | Journal article
Contributors: Lee CJ; Lee LT; Tsai HC; Chang WH; Lee IH; Chen KC; Chang HH; Chen PS; Yang YK
Source: Self-asserted source
Hui Hua Chang

FGF21 Is Associated with Metabolic Effects and Treatment Response in Depressed Bipolar II Disorder Patients Treated with Valproate.

The international journal of neuropsychopharmacology
2018-04-01 | Journal article
Contributors: Chang HH; Chen PS; Cheng YW; Wang TY; Yang YK; Lu RB
Source: Self-asserted source
Hui Hua Chang

Plasma oxytocin levels in major depressive and bipolar II disorders.

Psychiatry research
2017-08-30 | Journal article
Contributors: Lien YJ; Chang HH; Tsai HC; Kuang Yang Y; Lu RB; See Chen P
Source: Self-asserted source
Hui Hua Chang

rs2841277 (<i>PLD4</i>) is associated with susceptibility and rs4672495 is associated with disease activity in rheumatoid arthritis.

Oncotarget
2017-07-18 | Journal article
Contributors: Chen WC; Wen-Chang Wang; Okada Y; Chang WP; Chou YH; Chang HH; Huang JD; Chen DY; Chang WC
Source: Self-asserted source
Hui Hua Chang

Effect of memantine on C-reactive protein and lipid profiles in bipolar disorder.

Journal of affective disorders
2017-06-09 | Journal article
Contributors: Chang HH; Chen PS; Wang TY; Lee SY; Chen SL; Huang SY; Jau-Shyong Hong; Yang YK; Lu RB
Source: Self-asserted source
Hui Hua Chang

C-reactive protein as a differential biomarker of bipolar versus unipolar depression: Response.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
2016-09-02 | Journal article
Contributors: Chang HH; Chen PS
Source: Self-asserted source
Hui Hua Chang

C-reactive protein: A differential biomarker for major depressive disorder and bipolar II disorder.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
2016-04-20 | Journal article
Contributors: Chang HH; Wang TY; Lee IH; Lee SY; Chen KC; Huang SY; Yang YK; Lu RB; Chen PS
Source: Self-asserted source
Hui Hua Chang

Association between ABCB1 Polymorphisms and Antidepressant Treatment Response in Taiwanese Major Depressive Patients.

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology
2015-12-01 | Journal article
Contributors: Chang HH; Chou CH; Yang YK; Lee IH; Chen PS
Source: Self-asserted source
Hui Hua Chang

MTOR inhibition enhances NVP-AUY922-induced autophagy-mediated KIT degradation and cytotoxicity in imatinib-resistant gastrointestinal stromal tumors.

Oncotarget
2014-11-01 | Journal article
Contributors: Yuan-Shuo Hsueh; Chang HH; Chiang NJ; Yen CC; Chien-Feng Li; Chen LT
Source: Self-asserted source
Hui Hua Chang

The change of insulin levels after six weeks antidepressant use in drug-naïve major depressive patients.

Journal of affective disorders
2013-05-09 | Journal article
Contributors: Chang HH; Chi MH; Lee IH; Tsai HC; Gean PW; Yang YK; Lu RB; Chen PS
Source: Self-asserted source
Hui Hua Chang

The prevalence of metabolic syndrome in drug-naïve bipolar II disorder patients before and after twelve week pharmacological intervention.

Journal of affective disorders
2012-09-25 | Journal article
Contributors: Hung Chi M; Hua Chang H; Tzeng NS; Huang SY; kueiru chou; Chun Tsai H; Kuang Yang Y; Lu RB; See Chen P
Source: Self-asserted source
Hui Hua Chang

Treatment response and cognitive impairment in major depression: association with C-reactive protein.

Brain, behavior, and immunity
2011-08-04 | Journal article
Contributors: Chang HH; Lee IH; Gean PW; Lee SY; Chi MH; Yang YK; Lu RB; Chen PS
Source: Self-asserted source
Hui Hua Chang

Comparison of antidepressant efficacy-related SNPs among Taiwanese and four populations in the HapMap database.

Journal of the Formosan Medical Association = Taiwan yi zhi
2011-07-01 | Journal article
Contributors: Chi MH; Lee SY; Chang HH; Yang YK; Lin E; Chen PS
Source: Self-asserted source
Hui Hua Chang

TPH1 is associated with major depressive disorder but not with SSRI/SNRI response in Taiwanese patients.

Psychopharmacology
2010-10-14 | Journal article
Contributors: Wang HC; Yeh TL; Chang HH; Gean PW; Chi MH; Yang YK; Lu RB; Chen PS
Source: Self-asserted source
Hui Hua Chang

Brain derived neurotrophic factor gene polymorphism (Val66Met) and short-term antidepressant response in major depressive disorder.

Journal of affective disorders
2010-08-01 | Journal article
Contributors: Chi MH; Chang HH; Lee SY; Lee IH; Gean PW; Yang YK; Lu RB; Chen PS
Source: Self-asserted source
Hui Hua Chang

The role of valproate in metabolic disturbances in bipolar disorder patients.

Journal of affective disorders
2010-01-13 | Journal article
Contributors: Chang HH; Yang YK; Gean PW; Huang HC; Chen PS; Lu RB
Source: Self-asserted source
Hui Hua Chang

Voriconazole inhibition of tacrolimus metabolism in a kidney transplant recipient with fluconazole-resistant cryptococcal meningitis.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2009-08-07 | Journal article
Contributors: Chang HH; Lee NY; Wen-Chien Ko; Lee HC; Yang YH; Wu CJ; Chang CM
Source: Self-asserted source
Hui Hua Chang

Interaction of serotonin-related genes affects short-term antidepressant response in major depressive disorder.

Progress in neuro-psychopharmacology & biological psychiatry
2009-06-26 | Journal article
Contributors: Lin E; Chen PS; Chang HH; Gean PW; Tsai HC; Yang YK; Lu RB
Source: Self-asserted source
Hui Hua Chang

High prevalence of metabolic disturbances in patients with bipolar disorder in Taiwan.

Journal of affective disorders
2009-02-04 | Journal article
Contributors: Chang HH; Chou CH; Chen PS; Gean PW; Huang HC; Lin CY; Yang YK; Lu RB
Source: Self-asserted source
Hui Hua Chang

Peer review (2 reviews for 2 publications/grants)

Review activity for Journal of affective disorders. (1)
Review activity for Journal of biomedical science (1)