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Biography

Experienced Radiochemist specializing in radiopharmaceutical research with a focus on radiotracer development and preclinical imaging. My journey in this field has been defined by a commitment to advancing chemical radiolabeling techniques and a deep understanding of the complex chemistry required for binding radioisotopes to targeting molecules. I have honed my skills in Nano-PET/CT imaging, enabling precise visualization and analysis of radiotracer biodistribution in small animal models.

Activities

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Employment (1)

King Faisal Specialist Hospital & Research Centre: Riyadh, SA

2010-12 to present | Radiochemist III (Cyclotron and Radiopharmaceuticals Department)
Employment
Source: Self-asserted source
Yousif Almalki

Education and qualifications (1)

King Saud University: Riyadh, Riyadh, SA

2005-02-02 to 2009-03-08 | BSc (Biochemistry)
Education
Source: Self-asserted source
Yousif Almalki

Works (41)

Synthesis, characterization and density functional theory of 64Cu based complex for hypoxia imaging

Journal of King Saud University - Science
2024-10 | Journal article
DOI: 10.1016/j.jksus.2024.103398
Part of ISSN: 1018-3647
Contributors: NORAH ALHOKBANY; I. Aljammaz; B. Alotaibi; Y. AlMalki; S. Almasaari
Source: Self-asserted source
Yousif Almalki

Full automation of the radiosynthesis of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB) on the ALL IN ONE synthesizer

Journal of Radioanalytical and Nuclear Chemistry
2024-07 | Journal article
DOI: 10.1007/s10967-024-09355-3
Part of ISSN: 0236-5731
Part of ISSN: 1588-2780
Contributors: Mohammed Al-Qahtani; Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Development of a new 64Cu-Semicarbazone Complex: Potential Theragnostic Radiopharmaceutical for Hypoxic Tumor.

Nuclear Medicine and Biology
2023-12 | Journal article
DOI: 10.1016/j.nucmedbio.2023.108805
Contributors: Y.Almalki; S.Okarvi; B.Alotaibi; I.Aljammaz
Source: Self-asserted source
Yousif Almalki

Investigating several reaction factors and methodologies for the radiosynthesis of N-Succinimidyl 4-[18F]fluorobenzoate ([18F]SFB)

3rd International Conference on Radioanalytical and Nuclear Chemistry (RANC 2023)
2023-05-07 | Conference paper | Methodology, Software, Validation
Contributors: Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Data from β-Catenin Attenuation Inhibits Tumor Growth and Promotes Differentiation in a BRAF<sup>V600E</sup>-Driven Thyroid Cancer Animal Model

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.c.6543208.v1
Contributors: Minjing Zou; Huda A. BinEssa; Yousif H. Al-Malki; Suhad Al-Yahya; Monther Al-Alwan; Ibrahim Al-Jammaz; Khalid S.A. Khabar; Falah Almohanna; Abdullah M. Assiri; Brian F. Meyer et al.
Source: check_circle
Crossref

Data from β-Catenin Attenuation Inhibits Tumor Growth and Promotes Differentiation in a BRAF<sup>V600E</sup>-Driven Thyroid Cancer Animal Model

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.c.6543208
Contributors: Minjing Zou; Huda A. BinEssa; Yousif H. Al-Malki; Suhad Al-Yahya; Monther Al-Alwan; Ibrahim Al-Jammaz; Khalid S.A. Khabar; Falah Almohanna; Abdullah M. Assiri; Brian F. Meyer et al.
Source: check_circle
Crossref

Fig. S1 from β-Catenin Attenuation Inhibits Tumor Growth and Promotes Differentiation in a BRAF<sup>V600E</sup>-Driven Thyroid Cancer Animal Model

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22521871
Contributors: Minjing Zou; Huda A. BinEssa; Yousif H. Al-Malki; Suhad Al-Yahya; Monther Al-Alwan; Ibrahim Al-Jammaz; Khalid S.A. Khabar; Falah Almohanna; Abdullah M. Assiri; Brian F. Meyer et al.
Source: check_circle
Crossref

Fig. S1 from β-Catenin Attenuation Inhibits Tumor Growth and Promotes Differentiation in a BRAF<sup>V600E</sup>-Driven Thyroid Cancer Animal Model

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22521871.v1
Contributors: Minjing Zou; Huda A. BinEssa; Yousif H. Al-Malki; Suhad Al-Yahya; Monther Al-Alwan; Ibrahim Al-Jammaz; Khalid S.A. Khabar; Falah Almohanna; Abdullah M. Assiri; Brian F. Meyer et al.
Source: check_circle
Crossref

Fig. S2 from β-Catenin Attenuation Inhibits Tumor Growth and Promotes Differentiation in a BRAF<sup>V600E</sup>-Driven Thyroid Cancer Animal Model

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22521868.v1
Contributors: Minjing Zou; Huda A. BinEssa; Yousif H. Al-Malki; Suhad Al-Yahya; Monther Al-Alwan; Ibrahim Al-Jammaz; Khalid S.A. Khabar; Falah Almohanna; Abdullah M. Assiri; Brian F. Meyer et al.
Source: check_circle
Crossref

Fig. S2 from β-Catenin Attenuation Inhibits Tumor Growth and Promotes Differentiation in a BRAF<sup>V600E</sup>-Driven Thyroid Cancer Animal Model

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22521868
Contributors: Minjing Zou; Huda A. BinEssa; Yousif H. Al-Malki; Suhad Al-Yahya; Monther Al-Alwan; Ibrahim Al-Jammaz; Khalid S.A. Khabar; Falah Almohanna; Abdullah M. Assiri; Brian F. Meyer et al.
Source: check_circle
Crossref

Development of new copper-64 labeled rhodamine: a potential PET myocardial perfusion imaging agent

EJNMMI Radiopharmacy and Chemistry
2022-12 | Journal article
DOI: 10.1186/s41181-022-00171-2
Part of ISSN: 2365-421X
Contributors: NORAH ALHOKBANY; Ibrahim AlJammaz; Basem AlOtaibi; Yousif AlMalki; Bander AlJammaz; Subhani M. Okarvi
Source: Self-asserted source
Yousif Almalki

Development and pre-clinical evaluation of new 64Cu-NOTA-folate conjugates for PET imaging of folate receptor-positive tumors

Nuclear Medicine and Biology
2022-11 | Journal article
DOI: 10.1016/s0969-8051(22)02238-7
Part of ISSN: 0969-8051
Contributors: Norah Alhokbany; Ibrahim Aljammaz; Basem AlOtaibi; Yousif Almalki; Subhani Okarvi
Source: Self-asserted source
Yousif Almalki

The effect of base strengths on the radiochemical yields of S[18F]FB synthesis

Nuclear Medicine and Biology
2022-05 | Journal article
DOI: 10.1016/s0969-8051(22)00184-6
Part of ISSN: 0969-8051
Contributors: Mohammed Al-Qahtani; Hussain Al Jabr; Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Development of new Copper-64 labeled Rhodamine: A potential PET myocardial perfusion imaging agent

2022-05-26 | Preprint
DOI: 10.21203/rs.3.rs-1545968/v1
Contributors: I. aljammaz; N. Al-Hokbany; B. Al-Otaibi; Y. Al-Malki; B. AlJammaz; S. M. Okarvi
Source: Self-asserted source
Yousif Almalki

Preclinical Evaluation of 124I-Radionuclide for PET/CT Imaging System

Biomedical Journal of Scientific &amp; Technical Research
2022-03-08 | Journal article | Investigation
DOI: 10.26717/bjstr.2022.42.006749
Part of ISSN: 2574-1241
Contributors: Sitah F Alanazi; Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Fast Fluorine-18 labeling and preclinical evaluation of novel Mucin1 and its Folate hybrid peptide conjugate for targeting breast carcinoma

EJNMMI Radiopharmacy and Chemistry
2021-12 | Journal article
DOI: 10.1186/s41181-021-00127-y
Part of ISSN: 2365-421X
Contributors: I. Al Jammaz; B. Al-Otaibi; Y. Al-Malki; A. Abousekhrah; S. M. Okarvi
Source: Self-asserted source
Yousif Almalki

Synthesis, Radiolabeling, and Biological Evaluation of 68Ga-Mucin1 and Its Folate Hybrid Peptide Conjugates for the Diagnosis of Ovarian Cancer

Journal of Chemistry
2021-09-23 | Journal article
DOI: 10.1155/2021/2329676
Part of ISSN: 2090-9071
Part of ISSN: 2090-9063
Contributors: Samiah Alhabardi; Hesham Radwan; Basim Alotaibi; Yousif Almalki; Ehab Elzayat; Zakia Shinwari; Subhani M. Okarvi; ibrahim aljammaz
Source: Self-asserted source
Yousif Almalki

β-Catenin Attenuation Inhibits Tumor Growth and Promotes Differentiation in a BRAFV600E-Driven Thyroid Cancer Animal Model

Molecular Cancer Therapeutics
2021-09-01 | Journal article
DOI: 10.1158/1535-7163.mct-21-0037
Part of ISSN: 1535-7163
Part of ISSN: 1538-8514
Contributors: Minjing Zou; Huda A. BinEssa; Suhad Al-Yahya; Monther Al-Alwan; Ibrahim Al-Jammaz; Khalid S.A. Khabar; Falah Almohanna; Abdullah M. Assiri; Brian F. Meyer; Ali S. Alzahrani et al.
Source: Self-asserted source
Yousif Almalki
grade
Preferred source (of 2)‎

Evaluation of the Small-animal Nano Scan PET/CT System using 89Zr

Current Medical Imaging Formerly Current Medical Imaging Reviews
2021-02 | Journal article | Author
DOI: 10.2174/1573405616666201012154548
Part of ISSN: 1573-4056
Contributors: Khalid Alzimami; Sitah Alanazi; Magdi Gannam; Ahmed Alenezi; Ibrahim Aljamaz; Suliman Alyanbawi; Basem Alotaibi; Yousif Almalki; Abdelmoneim Sulieman; Salem Sassi
Source: Self-asserted source
Yousif Almalki
grade
Preferred source (of 2)‎

Fast Fluorine-18 Labeling and Preclinical Evaluation of Novel Mucin1 and its Folate Hybrid Peptide conjugate for Targeting Breast Carcinoma.

2020-04-17 | Preprint
DOI: 10.21203/rs.3.rs-22192/v1
Contributors: ibrahim aljammaz; Basem Al-Otaibi; Yousif Al-Malki; Abdel Abousekhrah; S. M. Okarvi
Source: Self-asserted source
Yousif Almalki

New automated approach for the radio synthesis of S[18F]FB as a labelling intermediate for fluorine-18 radiotracers

6th International Conference on Radiation Medicine (ICRM2020)
2020-02 | Conference paper
Contributors: Mohammed Al-Qahtani; Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Laminin Derivative Peptide labelled with Iodine-131 have Promising Therapeutic Properties for a Specific Melanoma Cells

RANC 2019
2019-03 | Conference paper
Contributors: Mohammed Al-Qahtani; Yousif Almalki
Source: Self-asserted source
Yousif Almalki

New promising modified peptide with DOTA-NHS-ester labeled with Ga–68 as early cancers diagnostic tool

RANC 2019
2019-03 | Conference paper
Contributors: Mohammed Al-Qahtani; Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Ga-68 Nanoparticles and Ultra-small Nanoparticle: Next Generation of PET Radiopharmaceuticals?

Current Radiopharmaceuticals
2018-08-06 | Journal article
DOI: 10.2174/1874471011666180418110206
Part of ISSN: 1874-4710
Contributors: Mohammed Al-Qahtani; Yousif Al Malki; Hadeel Mutwali; Edward Helal-Neto; Ralph Santos-Oliveira
Source: Self-asserted source
Yousif Almalki

68Ga–Radiolabeling of Short Peptide with DOTA-NHS-ester investigated by HPLC

ICRM18
2018-02 | Conference paper
Contributors: Mohammed Al-Qahtani; Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Biological evaluations of laminin derivatives that have a potential as an imaging tools for angiogenesis

ICRM18
2018-02 | Conference paper
Contributors: Mohammed Al-Qahtani; Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Biological Evaluation of Hybrid Peptide Radiolabeled with 68Ga emitter as Melanoma Targeting Probe

European Journal of Nuclear Medicine and Molecular Imaging
2017 | Conference abstract
Contributors: Mohammed Al-Qahtani; Yousif Almalki
Source: Self-asserted source
Yousif Almalki

New labeled (TC)-T-99m-HYNIC-short peptide as a potential tumor specific anticancer imaging agent

Journal of Labelled Compounds
2017 | Journal article | Investigation, Methodology
Contributors: Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Development of aptamer anti-MUC1 labelled with Na-22 and Ga-68 as a positron emission tomography radiopharmaceutical

Latin American Journal of Pharmacy
2016 | Conference paper
Contributors: Mohammed Al-Qahtani; Yousif Almalki
Source: Self-asserted source
Yousif Almalki

[68Ga]Radiolabelling of short peptide that has a pet imaging potential

18th European Symposium onRadiopharmacy and Radiopharmaceuticals
2016-04 | Conference paper
Contributors: Mohammed Al-Qahtani; Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Investigating Differences in Radiochemical Yields between Several Radioiodinated Intermediates

2014 KFSH&RC Annual Research Report
2015-04 | Conference paper
Contributors: Mohammed Al-Qahtani; Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Production and Quality Control of [18F]FLT at our Institution

2014 KFSH&RC Annual Research Report
2015-04 | Conference paper
Contributors: Mohammed Al-Qahtani; Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Production of [18F]Fluoromethylcholine at our Institution

2014 KFSH&RC Annual Research Report
2015-04 | Conference paper
Contributors: Yousif Almalki; Mohammed Al-Qahtani
Source: Self-asserted source
Yousif Almalki

A COMPARISON STUDY OF SEVERAL RADIOIODINATED INTERMEDIATES FOR LABELLING SHORT PEPTIDES

the fourth International Nuclear Chemistry Congress (4th-INCC)
2014-12 | Conference paper
Contributors: Yousif Almalki; Mohammed Al-Qahtani
Source: Self-asserted source
Yousif Almalki

Evaluating radiolabeled peptides that has a potential as angiogenesis imaging radiotracers

2013 KFSH&RC Annual Research Report
2013-04 | Conference paper
Contributors: Yousif Almalki; Mohammed Al-Qahtani
Source: Self-asserted source
Yousif Almalki

Radiolabeling short peptides that have a potential as imaging radiotracers

the seventh International Symposium on Radiohalogens (7ISR)
2012-12 | Conference paper | Investigation
Contributors: Yousif Almalki
Source: Self-asserted source
Yousif Almalki

JASCO LC-4000 Series HPLC Systems and ChromNAV Software Training Course in Cremella, Italian

Software | Software
Contributors: Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Phantom for Testing Drug-Cell Interaction

Patent
Contributors: Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Preclinical Application Training Course (NanoScan PET/MRI/SPECT/CT, Interview FUSION) Budapest, Hungary. September 2018

Software
Contributors: Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Radiolabeling of DFKLFAVY peptide as a targeted imaging radiotracer for angiogenesis

20th International Symposium on Radiopharmaceutical Sciences S357
Conference paper | Investigation
Contributors: Yousif Almalki; Mohammed Al Qahtani
Source: Self-asserted source
Yousif Almalki

Trasis Software Training Course in Belgium

Software
Contributors: Yousif Almalki
Source: Self-asserted source
Yousif Almalki

Peer review (2 reviews for 1 publication/grant)

Review activity for Computational and Structural Biotechnology Journal (2)
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