Personal information

Activities

Employment (1)

First Affiliated Hospital of Zhengzhou University: Zhengzhou, CN

2014-07-15 to present (Department of Pharmacy)
Employment
Source: Self-asserted source
Shuaibing Liu

Education and qualifications (1)

Soochow University: Suzhou, Jiangsu, CN

2007-09-01 to 2014-06-30 | Master (Department of Pharmacy)
Education
Source: Self-asserted source
Shuaibing Liu

Funding (1)

Influence of metabolic enzymes, transporters and target receptors gene polymorphisms on pharmacokinetics and platelet response of ticagrelor

2017-01 to 2019-12 | Grant
National Natural Science Foundation of China (Beijing, CN)
Source: Self-asserted source
Shuaibing Liu

Works (32)

Ciprofol is primarily glucuronidated by UGT1A9 and predicted not to cause drug-drug interactions with typical substrates of CYP1A2, CYP2B6, and CYP2C19

Chemico-Biological Interactions
2024 | Journal article
EID:

2-s2.0-85181178519

Part of ISSN: 18727786 00092797
Contributors: Hou, L.; Zhao, Y.; Zhao, S.; Zhang, X.; Yao, X.; Yang, J.; Wang, Z.; Chan, E.C.Y.; Liu, S.
Source: Self-asserted source
Shuaibing Liu via Scopus - Elsevier

Identification of the human Cytochrome P450 enzymes (P450s) responsible for metabolizing infigratinib to its pharmacologically active Metabolites, BHS697, and CQM157, and assessment of their in vitro inhibition of P450s and UDP-glucuronosyltransferases (UGTs)

Biochemical Pharmacology
2024 | Journal article
EID:

2-s2.0-85196967857

Part of ISSN: 18732968 00062952
Contributors: Liu, S.; Zhao, S.; Zhang, X.; Chun Yong Chan, E.; Wang, Z.; Li, H.; Tian, X.
Source: Self-asserted source
Shuaibing Liu via Scopus - Elsevier

Impact of CYP2C19, CYP2C9, CYP3A4, and FMO3 Genetic Polymorphisms and Sex on the Pharmacokinetics of Voriconazole after Single and Multiple Doses in Healthy Chinese Subjects

Journal of Clinical Pharmacology
2024 | Journal article
EID:

2-s2.0-85191077902

Part of ISSN: 15524604 00912700
Contributors: Liu, S.; Yao, X.; Tao, J.; Zhao, S.; Sun, S.; Wang, S.; Tian, X.
Source: Self-asserted source
Shuaibing Liu via Scopus - Elsevier

Integrated serum metabolomics, 16S rRNA sequencing and bile acid profiling to reveal the potential mechanism of gentiopicroside against nonalcoholic steatohepatitis in lean mice

Journal of Ethnopharmacology
2024 | Journal article
EID:

2-s2.0-85197528721

Part of ISSN: 18727573 03788741
Contributors: Li, Z.; Zhu, X.; Li, C.; Tang, R.; Zou, Y.; Liu, S.
Source: Self-asserted source
Shuaibing Liu via Scopus - Elsevier

m6A modification regulates drug-metabolizing enzymes and drug transporters,m6A 修饰对药物代谢酶和药物转运体的调控作用

Chinese Pharmacological Bulletin
2024 | Journal article
EID:

2-s2.0-85198378033

Part of ISSN: 10011978
Contributors: Zhao, S.-Y.; Liu, S.-B.; Wang, Y.-Q.; Tian, X.
Source: Self-asserted source
Shuaibing Liu via Scopus - Elsevier

Physiologically Based Pharmacokinetic Modeling to Investigate the Disease-Drug–Drug Interactions between Voriconazole and Nirmatrelvir/Ritonavir in COVID-19 Patients with CYP2C19 Phenotypes

Clinical Pharmacology and Therapeutics
2024 | Journal article
EID:

2-s2.0-85186908543

Part of ISSN: 15326535 00099236
Contributors: Wang, P.; Liu, S.; Yang, J.
Source: Self-asserted source
Shuaibing Liu via Scopus - Elsevier

Pharmacokinetics, pharmacodynamics, and safety of ciprofol emulsion in Chinese subjects with normal or impaired renal function

Frontiers in Pharmacology
2023 | Journal article
EID:

2-s2.0-85178960709

Part of ISSN: 16639812
Contributors: Tao, J.; Liu, S.; Zhao, Y.Y.; Qi, L.; Yan, P.; Wu, N.; Liu, X.; Liu, D.; Tian, X.
Source: Self-asserted source
Shuaibing Liu via Scopus - Elsevier

Pharmacokinetics, Pharmacodynamics, and Safety of Ciprofol Injectable in Chinese Subjects with Normal or Impaired Renal Function

Research Square
2023 | Other
EID:

2-s2.0-85167556786

Contributors: Tao, J.; Liu, S.; Zhao, Y.; Qi, L.; Yan, P.; Wu, N.; Liu, X.; Wang, X.; Liu, D.; Zhang, X. et al.
Source: Self-asserted source
Shuaibing Liu via Scopus - Elsevier

Bioequivalence Study of Iloperidone Tablets Under Fasting and Fed Conditions in Chinese Healthy Subjects,伊潘立酮片在中国健康受试者空腹和餐后条件下的生物等效性研究

Chinese Pharmaceutical Journal
2022 | Journal article
EID:

2-s2.0-85129350419

Part of ISSN: 10012494
Contributors: Wang, Y.-Q.; Li, Z.-Y.; Liu, S.-B.; Meng, Z.-B.; He, X.-L.; Peng, Y.-Y.; Zhang, X.-J.; Tian, X.
Source: Self-asserted source
Shuaibing Liu via Scopus - Elsevier

Population total and unbound pharmacokinetics and pharmacodynamics of ciprofol and M4 in subjects with various renal functions.

British journal of clinical pharmacology
2022-10-11 | Journal article | Author
Contributors: Shuaibing Liu; Yao X; Tao J; Yang JJ; Zhao YY; Liu DW; Wang SY; Sun SK; Wang X; Yan PK et al.
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

Development of Physiology Based Pharmacokinetic Model to Predict the Drug Interactions of Voriconazole and Venetoclax.

Pharmaceutical research
2022-06-21 | Journal article
Contributors: Shuaibing Liu; Dong J; Liu SB; Rasheduzzaman JM; Huang CR; Miao LY
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

Corrigendum: Predicting the Effects of CYP2C19 and Carboxylesterases on Vicagrel, a Novel P2Y12 Antagonist, by Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Approach (Frontiers in Pharmacology, (2020), 11, (591854), 10.3389/fphar.2020.591854)

Frontiers in Pharmacology
2021 | Journal article
EID:

2-s2.0-85105218082

Part of ISSN: 16639812
Contributors: Liu, S.; Wang, Z.; Tian, X.; Cai, W.
Source: Self-asserted source
Shuaibing Liu via Scopus - Elsevier

Determination of Sarpogrelate in Human Plasma by Liquid Chromatography with Tandem Mass Spectrometry and Its Application to a Bioequivalence Study,液相色谱-串联质谱法测定人血浆中沙格雷酯浓度及人体生物等效性研究

Chinese Pharmaceutical Journal
2021 | Journal article
EID:

2-s2.0-85107195357

Part of ISSN: 10012494
Contributors: Liu, S.-B.; Du, Y.; Wei, J.-Y.; Li, Z.-Y.; Zhang, X.-J.; Tian, X.
Source: Self-asserted source
Shuaibing Liu via Scopus - Elsevier

Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions.

Chemico-biological interactions
2021-12-12 | Journal article
Contributors: Shuaibing Liu; Liu S; Wang Z; Eric Chun Yong Chan; Zhao Y; Kang J; Zhang X; Tian X
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

Baicalin Enhanced Oral Bioavailability of Sorafenib in Rats by Inducing Intestine Absorption.

Frontiers in pharmacology
2021-11-08 | Journal article
Contributors: Shuaibing Liu; Wei J; Liu R; Zhang J; Liu S; Yan D; Wen X; Tian X
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

Contributions of UDP-Glucuronosyltransferases to Human Hepatic and Intestinal Metabolism of Ticagrelor and Inhibition of UGTs and Cytochrome P450 Enzymes by Ticagrelor and its Glucuronidated Metabolite.

Frontiers in pharmacology
2021-10-14 | Journal article
Contributors: Shuaibing Liu; Liu S; Hou L; Li C; Zhao Y; Yao X; Zhang X; Tian X
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

Analyzing Potential Intestinal Transporter Drug-Drug Interactions: Reevaluating Ticagrelor Interaction Studies.

Pharmaceutical research
2021-10-01 | Journal article
Contributors: Shuaibing Liu; Liu S; Sodhi JK; Leslie Z. Benet
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

Pharmacokinetics, Urinary Excretion, and Pharmaco-Metabolomic Study of Tebipenem Pivoxil Granules After Single Escalating Oral Dose in Healthy Chinese Volunteers.

Frontiers in pharmacology
2021-07-13 | Journal article
Contributors: Shuaibing Liu; Li Z; Su M; Cheng W; Xia J; Liu S; Liu R; Sun S; Feng L; Zhu X et al.
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

A Validated LC-MS/MS Method for the Simultaneous Determination of Ticagrelor, Its Two Metabolites and Major Constituents of Tea Polyphenols in Rat Plasma and Its Application in a Pharmacokinetic Study.

Journal of chromatographic science
2021-05-01 | Journal article | Author
Contributors: Xue Y; Wang Z; Weimin Cai; Tian X; Shuaibing Liu
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

In Vitro Metabolism of Ticagrelor and Its Metabolic Interactions with Statins,替格瑞洛的体外代谢及其与他汀类药物的相互作用研究

Chinese Pharmaceutical Journal
2020 | Journal article
EID:

2-s2.0-85101209748

Part of ISSN: 10012494
Contributors: Xue, Y.; Zhao, Y.-B.; Wang, Z.-T.; Cai, W.-M.; Liu, S.-B.
Source: Self-asserted source
Shuaibing Liu via Scopus - Elsevier

Predicting the Effects of CYP2C19 and Carboxylesterases on Vicagrel, a Novel P2Y12 Antagonist, by Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Approach.

Frontiers in pharmacology
2020-12-08 | Journal article
Contributors: Shuaibing Liu; Liu S; Wang Z; Tian X; Weimin Cai
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

A physiologically based pharmacokinetic/pharmacodynamic modeling approach for drug-drug interaction evaluation of warfarin enantiomers with sorafenib.

Drug metabolism and pharmacokinetics
2020-10-09 | Journal article
Contributors: Shuaibing Liu; Wang Z; Xiang X; Liu S; Tang Z; Hong Sun; Parvez M; Ghim JL; Shin JG; Cai W
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

Intestinal Efflux Transporters P-gp and BCRP Are Not Clinically Relevant in Apixaban Disposition.

Pharmaceutical research
2020-09-29 | Journal article
Contributors: Shuaibing Liu; Sodhi JK; Liu S; Leslie Z. Benet
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

Predicting the effect of tea polyphenols on ticagrelor by incorporating transporter-enzyme interplay mechanism.

Chemico-biological interactions
2020-08-20 | Journal article
Contributors: Shuaibing Liu; Liu S; Wang Z; Hou L; Tian X; Zhang X; Weimin Cai
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

Challenging the Relevance of Unbound Tissue-to-Blood Partition Coefficient Kpuu on Prediction of Drug-Drug Interactions.

Pharmaceutical research
2020-03-25 | Journal article
Contributors: Shuaibing Liu; Sodhi JK; Liu S; Benet LZ
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

Effect of tea polyphenols on the oral and intravenous pharmacokinetics of ticagrelor in rats and its in vitro metabolism.

Journal of food science
2020-03-10 | Journal article
Contributors: Shuaibing Liu; Wang ZT; Xue Y; Hong Sun; Hong Sun; Zhang Z; Tang ZJ; Liu SB; Weimin Cai
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

A Single Dose of Baicalin Has No Clinically Significant Effect on the Pharmacokinetics of Cyclosporine A in Healthy Chinese Volunteers.

Frontiers in pharmacology
2019-05-14 | Journal article
Contributors: Shuaibing Liu; Liu R; Xia Li; Wei J; Liu S; Chang Y; Zhang J; Zhang J; Zhang X; Fuhr U et al.
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

Population pharmacokinetics and pharmacodynamics of ticagrelor and AR-C124910XX in Chinese healthy male subjects.

European journal of clinical pharmacology
2018-02-13 | Journal article
Contributors: Shuaibing Liu; Liu S; Xue L; Shi X; Sun Z; Zhu Z; Zhang X; Tian X
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

Effect of CYP3A4∗1Gand CYP3A5∗3 Polymorphisms on Pharmacokinetics and Pharmacodynamics of Ticagrelor in Healthy Chinese Subjects.

Frontiers in pharmacology
2017-03-31 | Journal article
Contributors: Shuaibing Liu; Liu S; Shi X; Tian X; Xiaojian Zhang; Sun Z; Miao L
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

Pharmacokinetics of ropinirole determined by LC-MS/MS in rat plasma and striatum

Chinese Journal of New Drugs
2015 | Journal article
EID:

2-s2.0-84938823754

Part of ISSN: 10033734
Contributors: Wang, Z.-T.; Huang, C.-R.; Xu, Q.-Q.; Liu, S.-B.; Miao, L.-Y.
Source: Self-asserted source
Shuaibing Liu via Scopus - Elsevier

The genetic polymorphisms of POR*28 and CYP3A5*3 significantly influence the pharmacokinetics of tacrolimus in Chinese renal transplant recipients.

International journal of clinical pharmacology and therapeutics
2015-09-01 | Journal article
Contributors: Shuaibing Liu; Zhang JJ; Liu SB; Xue L; Ding XL; Zhang H; Miao LY
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

Determination of naloxone-3-glucuronide in human plasma and urine by HILIC-MS/MS.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
2013-10-23 | Journal article
Contributors: Shuaibing Liu; Dong J; Liu S; Zhang H; Hua Q; Zhao X; Miao L
Source: Self-asserted source
Shuaibing Liu
grade
Preferred source (of 2)‎

Peer review (3 reviews for 2 publications/grants)

Review activity for Clinical pharmacokinetics (1)
Review activity for Journal of ethnopharmacology. (2)