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zoonoses prevention, cancer evolution, mathematical modeling, arboviruses, dilution effect
France

Biography

Benjamin Roche is a distinguished research director with expertise in the intricate interplay between biodiversity and infectious diseases. He serves as the scientific advisor to the CEO of the French Research Institute for Sustainable Development (IRD) and is a Co-founder and Global Science Leader of PREZODE (Preventing Zoonotic Disease Emergence). Additionally, he holds the role of commissioner in the Lancet/PPATS commission dedicated to Preventing Viral Spillovers.
His research primarily revolves around bridging the realms of evolutionary ecology and public health, leveraging data analysis, mathematical modeling, and phylodynamic approaches. Dr. Roche investigates how the diversity of hosts and pathogens can influence the emergence and transmission of zoonotic diseases. He also explores integrated prevention strategies to mitigate these risks. Furthermore, his work delves into the intricate relationships between ecological and societal factors in the spread of pathogens, particularly examining the impact of human behavior. Beyond infectious disease epidemiology, he explores the effects of pathogen community structure on cancer incidence and severity. He develops theoretical models grounded in experimental data to understand the application of "adaptive therapy" in chemotherapy to delay the emergence of drug resistance.
In addition to his groundbreaking research endeavors, Dr. Roche collaborates extensively with both national and international health authorities. He plays a pivotal role in developing decision support tools, including advising governments during the COVID-19 crisis to inform public health policy. He is also actively engaged in the development and implementation of international prevention programs against potential pandemics, exemplified by his involvement in the PREZODE initiative. Driven by a commitment to fundamental research, his projects possess translational potential, offering opportunities to enhance public health strategies, particularly in resource-constrained regions.

Activities

Employment (4)

Institut de Recherche pour le Développement Délégation Régionale Occitanie: Montpellier, Languedoc-Roussillon, FR

2009-09 to present | Researcher (MIVEGEC)
Employment
Source: Self-asserted source
Benjamin Roche

Ecole Normale Supérieure Département de Biologie: Paris, Île-de-France, FR

2010-08 to 2011-08 | Researcher (Biology)
Employment
Source: Self-asserted source
Benjamin Roche

University of Michigan: Ann Arbor, MI, US

2009-08 to 2010-08 | Post-doctoral fellow (Ecology and Evolutionary Biology)
Employment
Source: Self-asserted source
Benjamin Roche

University of Georgia: Athens, GA, US

2008-08 to 2009 | Post-doctoral fellow (Odom School of Ecology)
Employment
Source: Self-asserted source
Benjamin Roche

Education and qualifications (3)

Sorbonne Université Campus Pierre et Marie Curie: Paris, Île-de-France, FR

2009-01 to 2017-03 | Habilitation à Diriger les Recherches (Medicine and Public Health)
Education
Source: Self-asserted source
Benjamin Roche

Communauté d'Universités et Etablissements Languedoc-Roussillon Universités: Montpellier, Languedoc-Roussillon, FR

2005 to 2008 | PhD in Ecology and Evolutionary biology
Education
Source: Self-asserted source
Benjamin Roche

Université Pierre et Marie Curie: Paris, Île-de-France, FR

2003-09-01 to 2004-06-30 | Mec Biomathematics
Education
Source: Self-asserted source
Benjamin Roche

Professional activities (4)

The Lancet/Preventing Pandemics at the Source: London, GB

2023 to 2025 | member (Commission on prevention of viral spillover)
Service
Source: Self-asserted source
Benjamin Roche

World Health Organization: Geneva, CH

2023 to 2024 | Co-chair of the WHO/PREZODE working-group on quanitative indicators for risk of zoonotic disease emergence
Service
Source: Self-asserted source
Benjamin Roche

French national research institute for sustainable Development: Marseille, FR

2021 to 2024 | One Health advisor to the CEO
Service
Source: Self-asserted source
Benjamin Roche

Ministère des Affaires Etrangères: Paris, FR

2021 | Medal of Honor
Distinction
Source: Self-asserted source
Benjamin Roche

Funding (18)

Research program (PEPR) of the PREZODE initiative

2023 to 2028 | Contract
Secretariat General pour l'investissement (Paris, FR)
Source: Self-asserted source
Benjamin Roche

Forecasting epidemiological and evolutionary consequences of co-infecting pathogens

2022 to 2026 | Grant
Agence Nationale de la Recherche (paris, FR)
Source: Self-asserted source
Benjamin Roche

SARS-COV-2 variants within an increasingly vaccinated population of Mexico City

2021 to 2023 | Grant
Agence Nationale de Recherches sur le Sida et les Hépatites Virales (Paris, FR)
Source: Self-asserted source
Benjamin Roche

International laboratory on biodiversity and pathogen transmission

2020 to 2030 | Contract
IRD (Marseille, FR)
Source: Self-asserted source
Benjamin Roche

Relationship between biodiversity and pathogen transmission in Yucatan

2020 to 2025 | Grant
Consejo Nacional de Ciencia y Tecnología (Mexico City, MX)
Source: Self-asserted source
Benjamin Roche

Impact of eco-epidemiological dilution effects on the risks of circulation and transmission of zoonotic pathogens in European small mammal communities

2020 to 2023 | Grant
Agence Nationale de la Recherche (paris, FR)
Source: Self-asserted source
Benjamin Roche

Chikungunya outbreak: role of human behavior

2014-06 to 2015-06 | Grant
ANRS (Montpellier, FR)
Source: Self-asserted source
Benjamin Roche

STORY

2014 to 2018 | Grant
Agence Nationale de la Recherche (Paris, FR)
Source: Self-asserted source
Benjamin Roche

Evolution of natural resistance to Cancer: Peto’s paradox revisited

2013 to 2017 | Grant
Agence Nationale de la Recherche (Paris, FR)
Source: Self-asserted source
Benjamin Roche

Biodiversity and pathogen transmission

2013 to 2015 | Grant
French Foundation for Biodiversity Research (Paris, FR)
Source: Self-asserted source
Benjamin Roche

Regional Epidemiological Landscape Amazon Information System

2012 to 2014 | Grant
CNPQ (Brasilia, BR)
Source: Self-asserted source
Benjamin Roche

Modeling of Aedes albopictus invasion in France

2012 to 2013 | Grant
French ministry of Health (Paris, FR)
Source: Self-asserted source
Benjamin Roche

Cartography of intercellular network within the tumoral microenvironment in lung cancer and its reaction to carboplatine

Grant
Institut National Du Cancer (Paris, FR)
Source: Self-asserted source
Benjamin Roche

Development of a tool to support the decision-making process for surveillance and vector control of dengue, chikungunya and Zika virus disease in Europe

Contract
European Centre for Disease Prevention and Control (Stockholm, SE)
Source: Self-asserted source
Benjamin Roche

Digital Epidemiology to anticipate COVID-19 transmission levels

Grant
Agence Nationale de la Recherche (Paris, FR)
Source: Self-asserted source
Benjamin Roche

Pathogen’s Niche: a new approach for infectious disease control (PANIC)

Grant
Agence Nationale de la Recherche (Paris, FR)
Source: Self-asserted source
Benjamin Roche

Preacts (Prezode in Action in the Global South)

Contract
Agence Française de Développement (Paris, FR)
Source: Self-asserted source
Benjamin Roche

Support for COVID-19 control in Africa

Grant
Agence Française de Développement (Paris, FR)
Source: Self-asserted source
Benjamin Roche