Cameron Mura (0000-0001-7985-2561)

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Biography

I'm a Senior Scientist and co-director of the Bourne & Mura Computational Biosciences Lab, based in the Department of Biomedical Engineering and School of Data Science at the University of Virginia; earlier on, I was an Assistant Professor of Chemistry at UVA (2008-2018). My scientific background, and most of my research interests, are in the areas of structural biology, molecular biophysics and computational biology, particularly as regards the evolution of RNA-associated ribonucleoprotein assemblies, protein folds, and protein-protein interactions. I'm also interested in data science and its attendant approaches (e.g., deep learning and other machine learning paradigms), chiefly as applied to the aforementioned scientific domains. Further information is available at http://bournelab.org.

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University of Virginia: Charlottesville, VA, US

2018-05 to present | Senior Scientist (School of Data Science and Dept of Biomedical Engineering)

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Cameron Mura

https://orcid.org/0000-0001-7985-2561

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Biography

Activities

Employment (3)

University of Virginia: Charlottesville, VA, US

University of Virginia: Charlottesville, VA, US

University of Virginia: Charlottesville, VA, US

Education and qualifications (4)

University of California San Diego: La Jolla, CA, US

University of California Los Angeles: Los Angeles, CA, US

University of California Los Angeles: Los Angeles, CA, US

Georgia Institute of Technology: Atlanta, GA, US

Funding (3)

CAREER: Experimental & Computational Studies of Ancient Sm-based RNA Assemblies

MRI: Acquisition of X-Ray Single-Crystal CCD Diffractometer at the University of Virginia

Known Structure, Unknown Function: An Undergraduate Research Curriculum

Research resources (1)

A Framework for Deep Generative Models of Protein Domain Structures

Works (48)

Ten simple rules for serving as an editor

A Tribute to Phil Bourne—Scientist and Human

Prop3D: A Flexible, Python-based Platform for Machine Learning with Protein Structural Properties and Biophysical Data

Ten Simple Rules for Serving as an Editor

Explainable Deep Generative Models, Ancestral Fragments, and Murky Regions of the Protein Structure Universe

Deep Generative Models of Protein Structure Uncover Distant Relationships Across a Continuous Fold Space

A Comparative Analysis of COVID-19 Vaccines Based on over 580,000 Cases from the Vaccination Adverse Event Reporting System

Real-world evidence for improved outcomes with histamine antagonists and aspirin in 22,560 COVID-19 patients

IL-13 Is a Driver of COVID-19 Severity

A Birds-eye (Re)View of Acid-suppression Drugs, COVID-19, and the Highly Variable Literature

Computational Prediction of Potential Inhibitors of the Main Protease of SARS-CoV-2.

Ten Simple Rules for Starting Research in Your Late Teens

Evidence for Treatment with Estradiol for Women with SARS-CoV-2 Infection

Deep Learning of Protein Structural Classes: Any Evidence for an ‘Urfold’?

The Urfold : Structural similarity just above the superfold level?

Ten Quick Tips for Using a Raspberry Pi

Machine Learning for Classification of Protein Helix Capping Motifs

Stimuli-Responsive, Pentapeptide, Nanofiber Hydrogel for Tissue Engineering

The Small β-Barrel Domain: A Survey-Based Structural Analysis

Structural Biology Meets Data Science: Does Anything Change?

Producing Hfq/Sm Proteins and sRNAs for Structural and Biophysical Studies of Ribonucleoprotein Assembly

Crystal Structure and RNA-binding Properties of an Hfq Homolog from the Deep-branching Aquificae: Conservation of the Lateral RNA-binding Mode

Toward a Designable Extracellular Matrix: Molecular Dynamics Simulations of an Engineered Laminin-Mimetic, Elastin-Like Fusion Protein

Understanding the Results of Electrostatics Calculations: Visualizing Molecular 'Isopotential' Surfaces

An Introduction to Programming for Bioscientists: A Python-Based Primer

Claws, Disorder, and Conformational Dynamics of the C-Terminal Region of Human Desmoplakin

Known Structure, Unknown Function: An Inquiry-based Undergraduate Biochemistry Laboratory Course

Interplay of the Bacterial Ribosomal A-site, S12 Protein Mutations and Paromomycin Binding: A Molecular Dynamics Study

An Introduction to Biomolecular Simulations and Docking

Development & Implementation of a PyMOL 'putty' Representation

Rapid Colorimetric Assays to Qualitatively Distinguish RNA and DNA in Biomolecular Samples

Archaeal and Eukaryotic Homologs of Hfq: A Structural and Evolutionary Perspective on Sm Function

Abstractions, Algorithms and Data Structures for Structural Bioinformatics in PyCogent

Molecular Dynamics of Potential rRNA Binders: Single-Stranded Nucleic Acids and Some Analogues

A Lightweight, Flow-based Toolkit for Parallel and Distributed Bioinformatics Pipelines

An Introduction to Biomolecular Graphics

PaPy: Parallel and Distributed Data-processing Pipelines in Python

RapA, the SWI/SNF Subunit of Escherichia coli RNA Polymerase, Promotes the Release of Nascent RNA from Transcription Complexes

Molecular Dynamics of a κB DNA Element: Base Flipping via Cross-strand Intercalative Stacking in a Microsecond-scale Simulation

Sm-like Protein Hfq: Location of the ATP-binding Site and the Effect of ATP on Hfq•RNA Complexes

Three-dimensional Structures of Fibrillar Sm Proteins: Hfq and Other Sm-like Proteins

The Oligomerization and Ligand-binding Properties of Sm-like Archaeal Proteins (SmAPs)

Structure and Assembly of an Augmented Sm-like Archaeal Protein 14-mer

Structure and Function of an Archaeal Homolog of Survival Protein E (SurEα): An Acid Phosphatase with Purine Nucleotide Specificity

The Structures, Functions, and Evolution of Sm-like Archaeal Proteins (SmAPs)

Structure of a Nudix Protein from Pyrobaculum aerophilum Reveals a Dimer with Two Intersubunit β–sheets

The Crystal Structure of a Heptameric Archaeal Sm Protein: Implications for the Eukaryotic SnRNP Core

Oxyanion-mediated Inhibition of Serine Proteases