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Scopus Author ID: 25121912600

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Works (27)

7TM domain structure of adhesion GPCRs

Handbook of Experimental Pharmacology
2016 | Book
DOI: 10.1007/978-3-319-41523-9_3
EID:

2-s2.0-84995428177
Contributors: de Graaf, C.; Nijmeijer, S.; Wolf, S.; Ernst, O.P.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Adhesion GPCRs in immunology

Biochemical Pharmacology
2016 | Journal article
DOI: 10.1016/j.bcp.2016.04.013
EID:

2-s2.0-84964940259
Contributors: Nijmeijer, S.; Vischer, H.F.; Leurs, R.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Classification, nomenclature, and structural aspects of adhesion GPCRs

Handbook of Experimental Pharmacology
2016 | Book
DOI: 10.1007/978-3-319-41523-9_2
EID:

2-s2.0-84995460989
Contributors: Krishnan, A.; Nijmeijer, S.; de Graaf, C.; Schiöth, H.B.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Adhesion G protein-coupled receptors: From in vitro pharmacology to in vivo mechanisms

Molecular Pharmacology
2015 | Journal article
DOI: 10.1124/mol.115.098749
EID:

2-s2.0-84939800716
Contributors: Monk, K.R.; Hamann, J.; Langenhan, T.; Nijmeijer, S.; Schöneberg, T.; Liebscher, I.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Combinatorial consensus scoring for ligand-based virtual fragment screening: A comparative case study for serotonin 5-HT<inf>3</inf>A, histamine H<inf>1</inf>, and Histamine H<inf>4</inf> receptors

Journal of Chemical Information and Modeling
2015 | Journal article
DOI: 10.1021/ci500694c
EID:

2-s2.0-84930199617
Contributors: Schultes, S.; Kooistra, A.J.; Vischer, H.F.; Nijmeijer, S.; Haaksma, E.E.J.; Leurs, R.; De Esch, I.J.P.; De Graaf, C.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Structure-based virtual screening for fragment-like ligands of the G protein-coupled histamine H<inf>4</inf> receptor

MedChemComm
2015 | Journal article
DOI: 10.1039/c5md00022j
EID:

2-s2.0-84930228441
Contributors: Istyastono, E.P.; Kooistra, A.J.; Vischer, H.F.; Kuijer, M.; Roumen, L.; Nijmeijer, S.; Smits, R.A.; De Esch, I.J.P.; Leurs, R.; De Graaf, C.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

The viral G protein-coupled receptor ORF74 hijacks β-arrestins for endocytic trafficking in response to human chemokines

PLoS ONE
2015 | Journal article
DOI: 10.1371/journal.pone.0124486
EID:

2-s2.0-84928905603
Contributors: De Munnik, S.M.; Kooistra, A.J.; Van Offenbeek, J.; Nijmeijer, S.; De Graaf, C.; Smit, M.J.; Leurs, R.; Vischer, H.F.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Bispyrimidines as potent histamine H4 receptor ligands: Delineation of structure-activity relationships and detailed H4 receptor binding mode

Journal of Medicinal Chemistry
2013 | Journal article
DOI: 10.1021/jm301886t
EID:

2-s2.0-84879033007
Contributors: Engelhardt, H.; Schultes, S.; De Graaf, C.; Nijmeijer, S.; Vischer, H.F.; Zuiderveld, O.P.; Dobler, J.; Stachurski, K.; Mayer, M.; Arnhof, H. et al.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Design and pharmacological characterization of VUF14480, a covalent partial agonist that interacts with cysteine 983.36 of the human histamine H4 receptor

British Journal of Pharmacology
2013 | Journal article
DOI: 10.1111/bph.12113
EID:

2-s2.0-84881629897
Contributors: Nijmeijer, S.; Engelhardt, H.; Schultes, S.; Van De Stolpe, A.C.; Lusink, V.; De Graaf, C.; Wijtmans, M.; Haaksma, E.E.J.; De Esch, I.J.P.; Stachurski, K. et al.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Detailed analysis of biased histamine H<inf>4</inf> receptor signalling by JNJ 7777120 analogues

British Journal of Pharmacology
2013 | Journal article
DOI: 10.1111/bph.12117
EID:

2-s2.0-84881359702
Contributors: Nijmeijer, S.; Vischer, H.F.; Sirci, F.; Schultes, S.; Engelhardt, H.; De Graaf, C.; Rosethorne, E.M.; Charlton, S.J.; Leurs, R.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Mapping histamine H&lt;inf&gt;4&lt;/inf&gt; receptor-ligand binding modes

MedChemComm
2013 | Journal article
DOI: 10.1039/c2md20212c
EID:

2-s2.0-84871799204
Contributors: Schultes, S.; Nijmeijer, S.; Engelhardt, H.; Kooistra, A.J.; Vischer, H.F.; De Esch, I.J.P.; Haaksma, E.E.J.; Leurs, R.; De Graaf, C.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Small and colorful stones make beautiful mosaics: Fragment-based chemogenomics

Drug Discovery Today
2013 | Journal article
DOI: 10.1016/j.drudis.2012.12.003
EID:

2-s2.0-84875710113
Contributors: De Graaf, C.; Vischer, H.F.; De Kloe, G.E.; Kooistra, A.J.; Nijmeijer, S.; Kuijer, M.; Verheij, M.H.P.; England, P.J.; Van Muijlwijk-Koezen, J.E.; Leurs, R. et al.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Analysis of multiple histamine H<inf>4</inf> receptor compound classes uncovers Gα<inf>i</inf> protein- and β-arrestin2-biased ligands

Molecular Pharmacology
2012 | Journal article
DOI: 10.1124/mol.112.080911
EID:

2-s2.0-84869825728
Contributors: Nijmeijer, S.; Vischer, H.F.; Rosethorne, E.M.; Charlton, S.J.; Leurs, R.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Development of a profiling strategy for metabolic mixtures by combining chromatography and mass spectrometry with cell-based gpcr signaling

Journal of Biomolecular Screening
2012 | Journal article
DOI: 10.1177/1087057112451922
EID:

2-s2.0-84869023823
Contributors: Nijmeijer, S.; Vischer, H.F.; Rudebeck, A.F.; Fleurbaaij, F.; Falck, D.; Leurs, R.; Niessen, W.M.A.; Kool, J.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

High-resolution metabolic profiling towards G protein-coupled receptors: Rapid and comprehensive screening of histamine H4 receptor ligands

Journal of Chromatography A
2012 | Journal article
DOI: 10.1016/j.chroma.2012.03.052
EID:

2-s2.0-84866322550
Contributors: Kool, J.; Rudebeck, A.F.; Fleurbaaij, F.; Nijmeijer, S.; Falck, D.; Smits, R.A.; Vischer, H.F.; Leurs, R.; Niessen, W.M.A.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Molecular pharmacology of histamine H4 receptors

Frontiers in Bioscience
2012 | Journal article
DOI: 10.2741/4039
EID:

2-s2.0-84860380065
Contributors: Nijmeijer, S.; De Graaf, C.; Leurs, R.; Vischer, H.F.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Virtual fragment screening: Discovery of histamine H<inf>3</inf> receptor ligands using ligand-based and protein-based molecular fingerprints

Journal of Chemical Information and Modeling
2012 | Journal article
DOI: 10.1021/ci3004094
EID:

2-s2.0-84871596792
Contributors: Sirci, F.; Istyastono, E.P.; Vischer, H.F.; Kooistra, A.J.; Nijmeijer, S.; Kuijer, M.; Wijtmans, M.; Mannhold, R.; Leurs, R.; De Esch, I.J.P. et al.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

A structural insight into the reorientation of transmembrane domains 3 and 5 during family A G protein-coupled receptor activation

Molecular Pharmacology
2011 | Journal article
DOI: 10.1124/mol.110.066068
EID:

2-s2.0-78751487961
Contributors: Sansuk, K.; Deupi, X.; Torrecillas, I.R.; Jongejan, A.; Nijmeijer, S.; Bakker, R.A.; Pardo, L.; Leurs, R.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H <inf>4</inf> and the ion channel serotonin 5-HT <inf>3A</inf>

Bioorganic and Medicinal Chemistry Letters
2011 | Journal article
DOI: 10.1016/j.bmcl.2011.06.123
EID:

2-s2.0-80051937251
Contributors: Verheij, M.H.P.; De Graaf, C.; De Kloe, G.E.; Nijmeijer, S.; Vischer, H.F.; Smits, R.A.; Zuiderveld, O.P.; Hulscher, S.; Silvestri, L.; Thompson, A.J. et al.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

G protein-coupled receptors: Walking hand-in-hand, talking hand-in-hand?

British Journal of Pharmacology
2011 | Journal article
DOI: 10.1111/j.1476-5381.2011.01229.x
EID:

2-s2.0-79954516650
Contributors: Vischer, H.F.; Watts, A.O.; Nijmeijer, S.; Leurs, R.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Molecular determinants of ligand binding modes in the histamine H <inf>4</inf> receptor: Linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies

Journal of Medicinal Chemistry
2011 | Journal article
DOI: 10.1021/jm201042n
EID:

2-s2.0-82555185524
Contributors: Istyastono, E.P.; Nijmeijer, S.; Lim, H.D.; Van De Stolpe, A.; Roumen, L.; Kooistra, A.J.; Vischer, H.F.; De Esch, I.J.P.; Leurs, R.; De Graaf, C.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Real-time visualization of heterotrimeric G protein Gq activation in living cells

BMC Biology
2011 | Journal article
DOI: 10.1186/1741-7007-9-32
EID:

2-s2.0-79957443605
Contributors: Adjobo-Hermans, M.J.W.; Goedhart, J.; van Weeren, L.; Nijmeijer, S.; Manders, E.M.M.; Offermanns, S.; Gadella Jr, T.W.J.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Triazole ligands reveal distinct molecular features that induce histaine H<inf>4</inf> receptor affinity and subtly govern H<inf>4</inf>/H<inf>3</inf> subtype selectivity

Journal of Medicinal Chemistry
2011 | Journal article
DOI: 10.1021/jm1013488
EID:

2-s2.0-79952812346
Contributors: Wijtmans, M.; De Graaf, C.; De Kloe, G.; Istyastono, E.P.; Smit, J.; Lim, H.; Boonnak, R.; Nijmeijer, S.; Smits, R.A.; Jongejan, A. et al.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Constitutive activity of the histamine H&lt;inf&gt;1&lt;/inf&gt; receptor

Methods in Enzymology
2010 | Book
DOI: 10.1016/B978-0-12-381298-8.00007-1
EID:

2-s2.0-78049309862
Contributors: Nijmeijer, S.; Leurs, R.; Vischer, H.F.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

The Epstein-Barr virus-encoded G protein-coupled receptor BILF1 hetero-oligomerizes with human CXCR4, scavenges Gαi proteins, and constitutively impairs CXCR4 functioning

Journal of Biological Chemistry
2010 | Journal article
DOI: 10.1074/jbc.M110.115618
EID:

2-s2.0-77956553602
Contributors: Nijmeijer, S.; Leurs, R.; Smit, M.J.; Vischer, H.F.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Significance of N-terminal proteolysis of CCL14a to activity on the chemokine receptors CCR1 and CCR5 and the human cytomegalovirus-encoded chemokine receptor US281

Journal of Immunology
2009 | Journal article
DOI: 10.4049/jimmunol.0802145
EID:

2-s2.0-70249107544
Contributors: Richter, R.; Casarosa, P.; Ständker, L.; Münch, J.; Springael, J.-Y.; Nijmeijer, S.; Forssmann, W.-G.; Vischer, H.F.; Vakili, J.; Detheux, M. et al.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier

Viral hijacking of human receptors through heterodimerization

Biochemical and Biophysical Research Communications
2008 | Journal article
DOI: 10.1016/j.bbrc.2008.09.082
EID:

2-s2.0-54449096236
Contributors: Vischer, H.F.; Nijmeijer, S.; Smit, M.J.; Leurs, R.
Source: Self-asserted source
Saskia Nijmeijer via Scopus - Elsevier
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