Personal information

Other IDs

SciProfiles: 2014517

Keywords

Treatment and clinical analysis of hypopharyngeal, nasopharyngeal, and sinonasal cancer, p53 family and CTTN/EMS1 gene and their relation to head and neck cancer as well as drug resistance, Impact of internal carotid artery invasion by head and neck cancer, Biomedical engineering and applications

Biography

Ching-Feng Lien received the M.B.B.S. degree from Kaohsiung Medical University, Taiwan, in 2003 and then received the Ph.D. degree in Institute of Imaging and Biomedical Photonics from National Chiao Tung University, Taiwan, in 2020. He is currently an attending doctor, the deputy head of the Department of Otolaryngology-Head and Neck Surgery, and the Director, Division of Rhinology, E-DA Hospital. His research interests include: treatment and clinical analysis of hypopharyngeal, nasopharyngeal, sinonasal cancer, and other head and neck cancer; p53 family and CTTN/EMS1 gene and their relation to head and neck cancer as well as drug resistance; impact of internal carotid artery invasion by head and neck cancer; biomedical engineering.

Activities

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Employment (2)

E-Da Hospital: Kaohsiung City, TW

2012-10-01 to present | Attending physician/deputy head of the Department of Otolaryngology-Head and Neck Surgery (Otolaryngology-Head and Neck Surgery)
Employment
Source: Self-asserted source
Ching-Feng Lien

Chi Mei Medical Center: Tainan City, TW

2010-07 to 2012-09 | Attending doctor (Otolaryngology-Head and Neck Surgery)
Employment
Source: Self-asserted source
Ching-Feng Lien

Education and qualifications (2)

National Yang Ming Chiao Tung University: Tainan, TW

2016-02-01 to 2020-01-31 | Ph.D. (Institute of Imaging and Biomedical Photonics)
Qualification
Source: Self-asserted source
Ching-Feng Lien

Kaohsiung Medical University: Kaohsiung City, TW

1998-09-01 to 2003-06-30 | MD (School of Medicine)
Education
Source: Self-asserted source
Ching-Feng Lien

Professional activities (4)

Taiwan Society of Otorhinolaryngology Head and Neck Surgery: Taipei, TW

Membership
Source: Self-asserted source
Ching-Feng Lien

Taiwan Society of Internal Medicine: Taipei, TW

Membership
Source: Self-asserted source
Ching-Feng Lien

Taiwan Head and Neck Society: Taipei, TW

Membership
Source: Self-asserted source
Ching-Feng Lien

American Academy of Otolaryngology — Head and Neck Surgery: Alexandria, Virginia, US

Membership
Source: Self-asserted source
Ching-Feng Lien

Works (24)

Chlorophyllides repress gain-of-function p53 mutated HNSCC cell proliferation via activation of p73 and repression of p53 aggregation in vitro and in vivo

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
2025-03 | Journal article
DOI: 10.1016/j.bbadis.2025.167662
Part of ISSN: 0925-4439
Contributors: Bi-He Cai; Yi-Ting Wang; Chia-Chi Chen; Fang-Yu Yeh; Yu-Rou Lin; Ying-Chen Lin; Tze-You Wu; Kuan-Yo Wu; Ching-Feng Lien; Yu-Chen Shih et al.
Source: Self-asserted source
Ching-Feng Lien

Analysis of Prognostic Factors for Internal Carotid Artery Invasion by Nasopharyngeal Carcinoma

Cancers
2025-02-01 | Journal article
DOI: 10.3390/cancers17030488
Part of ISSN: 2072-6694
Contributors: Ching-Feng Lien; Shyh-An Yeh; Chiu-Shih Cheng; Feng-Yu Chiang; Tzer Zen Hwang; Bi-He Cai; Chih-Yi Liu; Hsu-Huei Weng; Chia Chi Chen; Meng-Che Hsieh
Source: Self-asserted source
Ching-Feng Lien

Comparison of EMG amplitudes recorded by ipsilateral and contralateral electrodes placement during using trans-thyroid cartilage recording method in thyroid surgery.

Frontiers in endocrinology
2024-01-16 | Journal article
DOI: 10.3389/fendo.2023.1305629
PMID: 38292768
PMC: PMC10826414
Contributors: Chiang FY; Shih YC; Lien CF; Wang CC; Wang CC; Hwang TZ; Huang YC; Wu CW; Yeh TH; Huang TY
Source: Self-asserted source
Ching-Feng Lien

A Voice-Producing System With Naturalness and Variable Multi-Frequency Vocalization for Patients Who Have Undergone Laryngectomy

IEEE Access
2023 | Journal article | Author
DOI: 10.1109/access.2023.3262122
Part of ISSN: 2169-3536
Contributors: Tzu-Yen Huang; Bor-Shing Lin; Ching-Feng Lien; Wing-Hei Viola Yu; Yun-Yang Peng; Bor-Shyh Lin
Source: Self-asserted source
Ching-Feng Lien

Prognostic impact of cortactin in patients with hypopharyngeal cancer and its role for tegafur-uracil maintenance after adjuvant chemoradiotherapy

American journal of cancer research
2023-11-15 | Journal article
PMID: 38058839
PMC: PMC10695800
Contributors: Lien CF; Hwang TZ; Lin TM; Liu KW; Lin BS; Wang CC; Yang CC; Yeh SA; Hsieh MC
Source: Self-asserted source
Ching-Feng Lien

Proposals for Standardization of Intraoperative Facial Nerve Monitoring during Parotid Surgery.

Diagnostics (Basel, Switzerland)
2022-09-30 | Journal article | Author
DOI: 10.3390/diagnostics12102387
PMID: 36292076
PMC: PMC9600581
Contributors: Chiang FY; Ching-Feng Lien; Wang CC; Wang CC; Tzer Zen Hwang; Shih YC; Tseng HY; Che-Wei Wu; Huang YC; Tzu-Yen Huang
Source: Self-asserted source
Ching-Feng Lien

Platinum Plus Tegafur-Uracil versus Platinum Alone during Concurrent Chemoradiotherapy in Patients with Nonmetastatic Nasopharyngeal Carcinoma: A Propensity-Score-Matching Analysis.

Cancers
2022-09-17 | Journal article
DOI: 10.3390/cancers14184511
PMID: 36139674
PMC: PMC9496885
Contributors: Lien CF; Wang CC; Yang CC; Wang CC; Hwang TZ; Shih YC; Yeh SA; Hsieh MC
Source: Self-asserted source
Ching-Feng Lien

P63 and P73 Activation in Cancers with p53 Mutation

Biomedicines
2022-06 | Journal article | Author
DOI: 10.3390/biomedicines10071490
Contributors: Bi-He Cai; Yun-Chien Hsu; Fang-Yu Yeh; Yu-Rou Lin; Rui-Yu Lu; Si-Jie Yu; Jei-fu Shaw; Ming-Han Wu; Yi-Zhen Tsai; Ying-Chen Lin et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Necessity of Routinely Testing the Proximal and Distal Ends of Exposed Recurrent Laryngeal Nerve During Monitored Thyroidectomy.

Frontiers in endocrinology
2022-06-30 | Journal article
DOI: 10.3389/fendo.2022.923804
PMID: 35846324
PMC: PMC9279689
Contributors: Huang HY; Lien CF; Wang CC; Wang CC; Hwang TZ; Shih YC; Che-Wei Wu; Dionigi G; Huang TY; Chiang FY
Source: Self-asserted source
Ching-Feng Lien

Treatment Sequences in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: Cetuximab Followed by Immunotherapy or Vice Versa.

Cancers
2022-05-10 | Journal article
DOI: 10.3390/cancers14102351
PMID: 35625956
PMC: PMC9139601
Contributors: Yang CC; Lien CF; Hwang TZ; Wang CC; Wang CC; Shih YC; Yeh SA; Hsieh MC
Source: Self-asserted source
Ching-Feng Lien

The Effect of Cortactin Expression on Cervical Nodal Metastasis, Distant Metastasis and Survival-A Cohort Study of 140 Patients with Hypopharyngeal Carcinoma

The Journal of Taiwan Otolaryngology-Head and Neck Surgery
2022-03 | Journal article
Contributors: Ching-Feng Lien
Source: Self-asserted source
Ching-Feng Lien

The role of induction chemotherapy in patients with locally advanced head and neck squamous cell carcinoma: A nationwide population-based matched study.

Oral oncology
2022-03-29 | Journal article
DOI: 10.1016/j.oraloncology.2022.105848
PMID: 35364548
Contributors: Hsieh MC; Wang CC; Yang CC; Lien CF; Wang CC; Shih YC; Yeh SA; Hwang TZ
Source: Self-asserted source
Ching-Feng Lien

NAMPT Inhibitor and P73 Activator Represses P53 R175H Mutated HNSCC Cell Proliferation in a Synergistic Manner.

Biomolecules
2022-03-12 | Journal article
DOI: 10.3390/biom12030438
PMID: 35327630
PMC: PMC8946684
Contributors: Bi-He Cai; Bai ZY; Lien CF; Yu SJ; Lu RY; Wu MH; Wu WC; Chia Chi Chen; Yi-Chiang Hsu
Source: Self-asserted source
Ching-Feng Lien

Impact of Parenteral Glutamine Supplement on Oncologic Outcomes in Patients with Nasopharyngeal Cancer Treated with Concurrent Chemoradiotherapy.

Nutrients
2022-02-26 | Journal article
DOI: 10.3390/nu14050997
PMID: 35267972
PMC: PMC8912271
Contributors: Wang CC; Hwang TZ; Yang CC; Lien CF; Wang CC; Shih YC; Yeh SA; Hsieh MC
Source: Self-asserted source
Ching-Feng Lien

Correlation between Electrophysiological Change and Facial Function in Parotid Surgery Patients

Journal of Clinical Medicine
2021-12 | Journal article | Author
DOI: 10.3390/jcm10245730
Contributors: Feng-Yu Chiang; Chih-Chun Wang; Che-Wei Wu; I Cheng Lu; Pi-Ying Chang; Yi-Chu Lin; Ching-Feng Lien; Chien-Chung Wang; Tzu-Yen Huang; Tzer-Zen Hwang
Source: check_circle
Multidisciplinary Digital Publishing Institute

Tegafur-Uracil versus 5-Fluorouracil in Combination with Cisplatin and Cetuximab in Elderly Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Propensity Score Matching Analysis.

Biology
2021-10-08 | Journal article
DOI: 10.3390/biology10101011
PMID: 34681110
PMC: PMC8533478
Contributors: Hsieh MC; Wang CC; Yang CC; Lien CF; Wang CC; Shih YC; Yeh SA; Hwang TZ
Source: Self-asserted source
Ching-Feng Lien

Outcomes of patients with nasopharyngeal carcinoma treated with intensity-modulated radiotherapy.

Journal of radiation research
2021-05-01 | Journal article
DOI: 10.1093/jrr/rrab008
PMID: 33783535
PMC: PMC8127674
Contributors: Yeh SA; Hwang TZ; Wang CC; Yang CC; Lien CF; Wang CC; Hsu TY; Hsu RF; Shih YC; Huang YC et al.
Source: Self-asserted source
Ching-Feng Lien

Development of a Smart Assistance System for Patients With Blepharoptosis

IEEE Access
2019 | Journal article
DOI: 10.1109/access.2019.2946172
Part of ISSN: 2169-3536
Contributors: Ching-Feng Lien; Pei-Jung Wu; Lu-Xun Liao; Seng-Feng Jeng; Li-Ren Chang; Yen-Chun Lin; Bor-Shyh Lin
Source: Self-asserted source
Ching-Feng Lien

Comparison between open partial laryngectomy with tube-free tracheostomy and total laryngectomy for hypopharyngeal cancer with cartilage invasion.

Oncology letters
2018-08-13 | Journal article
DOI: 10.3892/ol.2018.9298
PMID: 30250561
PMC: PMC6144867
Contributors: Lien CF; Wang CC; Hwang TZ; Liu CF; Bor-Shyh Lin; Hsu-Huei Weng; Liu CY
Source: Self-asserted source
Ching-Feng Lien

Cortactin as a potential predictor of second esophageal neoplasia in hypopharyngeal carcinoma.

Auris, nasus, larynx
2018-08-11 | Journal article
DOI: 10.1016/j.anl.2018.08.002
PMID: 30107961
Contributors: Lien CF; Hwang TZ; Lin TM; Liu KW; Lin BS; Wang CC; Yang CC; Yeh SA
Source: Self-asserted source
Ching-Feng Lien

Development of Novel Lip-Reading Recognition Algorithm

IEEE Access
2017 | Journal article
DOI: 10.1109/access.2017.2649838
Part of ISSN: 2169-3536
Contributors: Bor-Shing Lin; Yu-Hsien Yao; Ching-Feng Liu; Ching-Feng Lien; Bor-Shyh Lin
Source: Self-asserted source
Ching-Feng Lien

Effect of carotid artery aberrancy on the distance between the vessel and nasopharyngeal subsites.

Journal of the Chinese Medical Association : JCMA
2014-03-30 | Journal article
DOI: 10.1016/j.jcma.2014.02.004
PMID: 24694671
Contributors: Lien CF; Hsu-Huei Weng; Lin BS; Liu CF; Wu TC; Lin YS
Source: Self-asserted source
Ching-Feng Lien

Risk factors for internal carotid artery injury in adults during simple nasopharyngeal surgeries.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
2013-08-28 | Journal article
DOI: 10.1007/s00405-013-2668-9
PMID: 23982669
Contributors: Lien CF; Hsu-Huei Weng; Liu CF; Lin BS; Wu TC; Lin YS
Source: Self-asserted source
Ching-Feng Lien

Computed tomographic analysis of frontal recess anatomy and its effect on the development of frontal sinusitis.

The Laryngoscope
2010-12-01 | Journal article
DOI: 10.1002/lary.20977
PMID: 20949581
Contributors: Lien CF; Hsu-Huei Weng; Chang YC; Lin YC; Wang WH
Source: Self-asserted source
Ching-Feng Lien
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